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Aksentijevic Lab

@dunjaaks.bsky.social
153 followers 168 following 58 posts

Cardiac metabolism research group 🫀⚡️ William Harvey Research Institute Queen Mary University of London

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Aksentijevic Lab @dunjaaks.bsky.social · 29/09/2026
I couldn’t have thought of a more fitting room to discuss my research on metabolism in heart failure on World Heart Day, in a room with mitochondria literally on the roof! 🫀🧬
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William Harvey Research Institute, QMUL @qmulwhri.bsky.social · 19/08/2026
🫀🔬 New research led by Prof @dunjaaks.bsky.social at @qmul.bsky.social finds excess sodium builds up in heart cells before structural heart disease appears in chronic kidney disease, and that the drug sotagliflozin can rapidly reverse it. 🔗 www.qmul.ac.uk/whri/latest-...
640 Human kidney medical diagram
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Aksentijevic Lab @dunjaaks.bsky.social · 19/08/2026
www.qmul.ac.uk/whri/latest-... Thank you @qmulwhri.bsky.social for highlighting our latest work
qmul.ac.uk
Excess sodium in heart cells may help explain heart damage linked to kidney disease
New research from Queen Mary University of London has identified a potential mechanism linking chronic kidney disease with changes in the heart, pointing towards new ways of understanding and potentia...
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Aksentijevic Lab @dunjaaks.bsky.social · 11/08/2026
New in Cardiovascular Research: 🫀 Na⁺ overload is an early driver of uraemic cardiomyopathy. Dual #SGLT1/2 inhibition normalises Na⁺ and restores cardiac metabolic homeostasis revealing a shared mechanism of cardioprotection across #CKD and #T2D. academic.oup.com/cardiovascre...
academic.oup.com
Dual inhibition of SGLT 1 and 2 by sotagliflozin alleviates intracellular sodium overload and improves cardiometabolic remodelling in uraemic cardiomyopathy
AbstractAims. Chronic kidney disease (CKD) is associated with uraemic cardiomyopathy characterised by early metabolic dysfunction. Elevated myocardial intr
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Aksentijevic Lab @dunjaaks.bsky.social · 05/08/2026
Can AI, omics, and organoids replace animal models in cardiovascular research? In our EU_METAHEART position paper in @Nature Reviews Cardiology we outline why animal models remain essential in cardiovascular research complementing emerging technologies. Read more: www.nature.com/articles/s41...
nature.com
In the era of AI, omics and organoids, animal models are still needed in cardiovascular research - Nature Reviews Cardiology
As artificial intelligence (AI), multiomics and human organoids reshape cardiovascular research, calls to replace animal models are accelerating. We argue that understanding complex, multiorgan cardio...
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Aksentijevic Lab @dunjaaks.bsky.social · 05/08/2026
Excited to share our latest paper🫀 We show that dual SGLT1/2 inhibition with sotagliflozin improves cardiac function and reshapes cardiac metabolism in type 2 diabetes. Read it here 👉🏻 www.nature.com/articles/s44...
nature.com
Dual SGLT1/2 inhibition with sotagliflozin improves cardiac function and metabolism in type 2 diabetic mice - npj Metabolic Health and Disease
npj Metabolic Health and Disease - Dual SGLT1/2 inhibition with sotagliflozin improves cardiac function and metabolism in type 2 diabetic mice
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Aksentijevic Lab @dunjaaks.bsky.social · 02/07/2026
To the world its a game. To all of us its coming together after unimaginable loss ..& still standing. #inat Thank you 🇧🇦🫶⚽️ #proudBosnian #dreambigdreamBiH FIFA World Cup 2026™ - Canada, Mexico and the United States
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Aksentijevic Lab @dunjaaks.bsky.social · 24/06/2026
The ISHR European Section Meeting is currently underway in Birmingham.It is always a pleasure to reconnect with colleagues from across Europe and beyond. A fantastic start to the day watching Mike Murphy deliver the Keith Reimer Distinguished Lecture. @mitoredox.bsky.social
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Aksentijevic Lab @dunjaaks.bsky.social · 12/06/2026
Idemo Bosno! 🇧🇦🫀🫶🍀⚽️ @fifaclubworldcup.bsky.social
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Aksentijevic Lab @dunjaaks.bsky.social · 04/06/2026
Honoured to be invited by the Rector of the University of Sarajevo to speak in my homeland alongside Luke O’Neill.Looking forward to discussions on science, research, and innovation with students and colleagues in🇧🇦
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Aksentijevic Lab @dunjaaks.bsky.social · 02/06/2026
Nature’s extremes can teach us so much about human biology. By studying bats, animals with extraordinary metabolic demands, we can gain new insights into cardiovascular health and disease. Our latest paper is out👉🏻🦇 journals.plos.org/plosone/arti...
journals.plos.org
Metabolomics-constrained modelling reveals dominant oxidative metabolism in the Egyptian fruit bat myocardium
Aim The present study aimed to elucidate which pathways contribute to cardiometabolic adaptation in Egyptian fruit bats. Methods Utilising cardiac tissues from Egyptian fruit bats (Rousettus aegypti...
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Aksentijevic Lab @dunjaaks.bsky.social · 02/06/2026
Two fantastic days in Manchester at #BSCR and #BCS meetings, combining science, networking, and Trustee duties. So proud of my group: Dr Ivana Iveljic (cardiooncology), Sanushe Dambure (CKD HFpEF genetics) Megan Young (NLRP3 inflammasome in HFpEF). Outstanding work from all! 👏🔬❤️
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Aksentijevic Lab @dunjaaks.bsky.social · 18/05/2026
Join us for @EU_METAHEART WG4 Webinar! 🫀 Tomorrow 13.00 London Time, 14.00 Berlin Time Link 👉🏻 ukw-de.zoom.us/j/9107037780...
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Aksentijevic Lab @dunjaaks.bsky.social · 21/04/2026
Join us for the EU_METAHEART WG4 Webinar! “From Omics to Mechanisms: Mechano-Energetic Uncoupling in Heart Failure”📆22 April 🕚12:00 (London) / 13:00 (Berlin) Hear from leading experts in cardiovascular research on proteomics, redox biology & cardiometabolic disease
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Aksentijevic Lab @dunjaaks.bsky.social · 01/04/2026
Some mornings in the lab are just better than others. 💙💛🇧🇦 🥼👩🏻‍🔬🧪
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Aksentijevic Lab @dunjaaks.bsky.social · 09/03/2026
Grateful for the opportunity to contribute to the new scientific statement from the European Society of Cardiology on metabolic dysfunction and cardiovascular disease.A great collaborative effort across ESC Basic Science Council and Working Groups. #ESC academic.oup.com/eurheartj/ad...
academic.oup.com
Novel cardiovascular metabolic risk factor mechanisms and therapeutic opportunities: A scientific statement of the ESC Council on Basic Cardiovascular Science, the ESC Working Group on Atherosclerosis...
Abstract. Metabolic disorders such as obesity, type 2 diabetes, and dyslipidaemia are major drivers of cardiovascular risk and have reached epidemic levels
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Aksentijevic Lab @dunjaaks.bsky.social · 27/02/2026
Thank you @qmulfmd.bsky.social for focus on our #immunometabolism study published earlier this week in @natureportfolio.nature.com Nature Cardiovascular Research 🫀 www.qmul.ac.uk/media/news/2...
qmul.ac.uk
Drug that targets immune cells shows potential as new treatment for diabetic heart disease
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Aksentijevic Lab @dunjaaks.bsky.social · 24/02/2026
Excited to share our latest paper in Nature Cardiovascular Research showing #diabetic #cardiomyopathy is driven by aberrant #immunometabolism Enhancing Treg migratory capacity restores immune balance and improves🫀dysfunction a promising new therapeutic direction in T2D www.nature.com/articles/s44...
nature.com
Targeting immunometabolic pathways with AZD1656 alleviates inflammation and metabolic dysfunction in type 2 diabetic cardiomyopathy - Nature Cardiovascular Research
Anderson et al. demonstrate that the glucokinase activator AZD1656 reduces inflammation and reverses cardiac dysfunction and metabolic remodeling in mice with diabetic cardiomyopathy.
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Mike Murphy @mitoredox.bsky.social · 23/02/2026
Congrats to Dunja on her latest paper just out in Nature Cardiovascular Research! doi.org/10.1038/s441...
doi.org
Targeting immunometabolic pathways with AZD1656 alleviates inflammation and metabolic dysfunction in type 2 diabetic cardiomyopathy - Nature Cardiovascular Research
Anderson et al. demonstrate that the glucokinase activator AZD1656 reduces inflammation and reverses cardiac dysfunction and metabolic remodeling in mice with diabetic cardiomyopathy.
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Aksentijevic Lab @dunjaaks.bsky.social · 23/02/2026
Thank you Mike!
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Aksentijevic Lab @dunjaaks.bsky.social · 22/02/2026
Honoured to be invited by French national TV to discuss our latest discoveries on naked mole rat cardiac metabolic and physiological resilience. Proud to see our published work featured alongside international leaders in the field. www.tf1.fr/tf1/jt-20h/v...
tf1.fr
Jamais malade : les secrets du rat-taupe nu - Journal de 20 heures | TF1+
[VIDÉO] Extrait en streaming sur TF1+ ▶️ 5m38s - Le rat-taupe nu passionne les biologistes. Originaire de la corne de l'Afrique, ce rongeur sans poils est l'un des animaux les plus étrangers au monde....
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Aksentijevic Lab @dunjaaks.bsky.social · 12/02/2026
If we want a more equitable and informed world, we must continue to promote literacy, champion education, and actively support women and girls in science not as an option, but as a responsibility.👩🏻‍🔬 #WomenInScienceDay
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Aksentijevic Lab @dunjaaks.bsky.social · 18/12/2025
An incredible morning at the @bloomberglp.bsky.social HQ in the heart of the City of London with Natasha Davidov Interviewed for the @bloomberglp.bsky.social _adria Leaders Programme-from women in research to naked mole-rat longevity and mending broken hearts.
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Aksentijevic Lab @dunjaaks.bsky.social · 17/12/2025
The best part of being an academic, Director of Education, and Programme Lead? Watching my students and mentees cross the stage and graduate. Their success is the real reward. 🎓
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Aksentijevic Lab @dunjaaks.bsky.social · 17/12/2025
Grateful for the opportunity to contribute to this international study🇦🇺🇬🇧: “Liraglutide-Driven Weight Loss Modulates Placental Remodeling in Obese Pregnancies in Mice”. Despite pre-conception weight loss with liraglutide, controlled diet led to better placental health. www.mdpi.com/3639816
mdpi.com
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Aksentijevic Lab @dunjaaks.bsky.social · 10/12/2025
Huge congratulations, Jan Miljkovic and Mike Murphy @mitoredox.bsky.social on your Nature Communications study out today! @natcomms.nature.com Grateful for the opportunity to collaborate and contribute to the team behind this important work. @qmulwhri.bsky.social www.nature.com/articles/s41...
nature.com
Simultaneous and sensitive quantification of protein and low molecular weight persulfides, polysulfides and H2S in biological samples - Nature Communications
Hydrogen sulfide (H2S) reversibly modifies low molecular weight and protein thiols to form persulfides (RSS−) and polysulfides (RS(S)nS−) for antioxidant defence and regulation of activity. Here, the ...
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Aksentijevic Lab @dunjaaks.bsky.social · 28/11/2025
I’m honoured to share that on Monday I will be inaugurated as an Honorary Professor of Medical Physiology University of Belgrade. My sincere thanks to the leadership of Belgrade Medical Faculty, especially Prof. Dragan Djuric. @qmulwhri.bsky.social med.bg.ac.rs?p=38549
med.bg.ac.rs
Приступно предавање – Проф. др Дуња Аксентијевић, Лондон, УК
Медицински факултет Универзитета у Београду обавештава Вас да ће на позив Катедре за медицинску физиологију, Проф. др Дуња Аксентијевић Professor of Cardiovascular Physiology & Metabolism Wellcome Tr...
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Aksentijevic Lab @dunjaaks.bsky.social · 21/11/2025
Our new study out in @natureportfolio.nature.com Scientific Reports shows #chronickidneydisease triggers systemic metabolic deficits that may drive cardiac dysfunction pointing to new cardio-renal therapeutic targets. Well done Megan! @qmulwhri.bsky.social @qmulfmd.bsky.social rdcu.be/eQ81P
rdcu.be
Altered systemic bioenergetic reserve in chronic kidney disease predisposes hearts to worse functional outcomes
Scientific Reports - Altered systemic bioenergetic reserve in chronic kidney disease predisposes hearts to worse functional outcomes
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Aksentijevic Lab @dunjaaks.bsky.social · 07/11/2025
Thank you so much Mike for coming to London and sharing this big milestone with me.
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Aksentijevic Lab @dunjaaks.bsky.social · 17/10/2025
Thrilled to see the EU METAHEART Family Edition from Nature Reviews Cardiology! 💓 My Science Barbie approves! @qmulwhri.bsky.social @qmulfmd.bsky.social @bartsmetabolism.bsky.social @natureportfolio.nature.com
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Aksentijevic Lab @dunjaaks.bsky.social · 15/10/2025
I have to be in the most epic academic office ever. Absolute legend vibes. 📚🔥Chris Faulkes 🙇🏻‍♀️🙇🏻‍♀️🙇🏻‍♀️
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Aksentijevic Lab @dunjaaks.bsky.social · 11/10/2025
What a privilege to witness courage, brilliance, and perseverance come together. Ivana’s PhD defence was pure inspiration a true hero’s journey. So proud! 🎓✨#proudmentor @qmulwhri.bsky.social
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Aksentijevic Lab @dunjaaks.bsky.social · 04/10/2025
I’m truly grateful to @klixban.bsky.social for sharing my story from Tuzla to London and my path in science. 🌍 This isn’t just about me, but about the mentors, colleagues, friends & family who believed in me. I hope it inspires others to follow their passions. ✨ www.klix.ba/scitech/nauk...
klix.ba
Ovo je priča o inspirativnom životnom putu Dunje Aksentijević: Od rodne Tuzle do uglednog naučnog statusa u Londonu
Brojni ljudi iz BiH koji su se odlučili na odlazak u inostranstvo ostvarili su značajne uspjehe posebno u polju nauke. Jedan od takvih primjera je i profesorica...
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Aksentijevic Lab @dunjaaks.bsky.social · 18/09/2025
Delighted to share our 2 new papers from Dr. Ivana Iveljić’s PhD 🎓 the first study from Bosnia & Herzegovina on long-term cardiac effects of adjuvant fluoropyrimidines in CRC survivors. Local research, global impact. 🌏🫀 👉🏻 medicinskiglasnik.ba/article/2242 👉🏻 www.medrxiv.org/content/10.1...
medicinskiglasnik.ba
Medicinski Glasnik
Medicinski Glasnik
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Aksentijevic Lab @dunjaaks.bsky.social · 18/09/2025
🌍 Delighted to attend #MetaHEART in Riga 🇱🇻 with Bosnian cardiology researchers 🇧🇦 Drs Jelena Jovanic & Ivana Iveljić. Dr Iveljić will give her invited talk on her recently completed PhD in cardiooncology 🧬 a testament to the resilience & talent in our EU_COST research community. 🫀#proudmentor
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Aksentijevic Lab @dunjaaks.bsky.social · 18/09/2025
Honoured to chair the keynote by my friend, collaborator, mentor & brilliant scientist Prof Damian Tyler🎤 at the annual EU METAHEART meeting in Riga, 🇱🇻 An inspiring talk showcasing cutting-edge cardiovascular science! 🧲🫀 #NMR @ox.ac.uk
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Aksentijevic Lab @dunjaaks.bsky.social · 18/09/2025
Hugely proud of Dr Megan Young for being a Young Investigator finalist at EU METAHEART annual meeting in Riga. She presented her Barts Charity funded project on mechano-energetics in diabetic cardiomyopathy-inspiring science with real impact! @qmulwhri.bsky.social @bartscharity.bsky.social
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Aksentijevic Lab @dunjaaks.bsky.social · 05/09/2025
Cardiac Metabolism session sponsored by BartsMetabolism Network at BSCR Autumn Meeting was 🔥! As Prof Heather said, ‘Two thorns (apparently me and Mike!), and a rose 🌹’ Exciting science, brilliant colleagues, and a whole lot of metabolism magic @heatherlab.bsky.social @mitoredox.bsky.social
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Mike Murphy @mitoredox.bsky.social · 26/06/2025
Good day yesterday at the William Harvey Research Institute Research Day where I was honoured to receive the Derek Willoughby Medal and give a lecture. Great hospitality from Dunja Aksentijevic and Sir Mark Caulfield.
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Aksentijevic Lab @dunjaaks.bsky.social · 26/06/2025
Thrilled to see Prof.Mike Murphy @mitoredox.bsky.social recognized at the @qmulwhri.bsky.social Research Day! His groundbreaking work in mitochondrial biology has shaped the field & inspired so many.Grateful for his mentorship over the years.And what a moment seeing these two scientific giants meet!
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Aksentijevic Lab @dunjaaks.bsky.social · 18/06/2025
Registration & abstract submissions are OPEN for #BSCR2025 at William Harvey Research Institute, QMUL! Programme & info: www.bscr.org/meetings/bsc... @qmulwhri.bsky.social
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Thomas Iskratsch @tiskratsch.bsky.social · 10/06/2025
📣Excited to host this year's BSCR Meeting at @qmullibrary.bsky.social QMUL (Sept 3/4), together with @dunjaaks.bsky.social with a stellar line up of invited speakers! Check out the website for more info and programme, as well as links for Registration and Abstract Submission: tinyurl.com/3e7xyjjp
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Aksentijevic Lab @dunjaaks.bsky.social · 09/06/2025
Thank you Mike!
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Aksentijevic Lab @dunjaaks.bsky.social · 04/06/2025
…Starting to feel very real! 🎓🥂
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Aksentijevic Lab @dunjaaks.bsky.social · 03/06/2025
I had the incredible opportunity to meet my scientific hero-someone whose work I've long admired, closely followed, and drawn immense inspiration from. @lukeanthonyoneill.bsky.social 🤩
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Aksentijevic Lab @dunjaaks.bsky.social · 22/04/2025
🦇🦇 New preprint out!🚨 We reveal unique cardiac metabolic adaptations in the Egyptian fruit bat—supporting flight, longevity & life in low oxygen. First cardiac metabolomic map in bats! 👉 www.biorxiv.org/content/10.1... @qmulwhri.bsky.social rossiterlab Fenn Cullen @anjakarlstaedt.bsky.social
biorxiv.org
Bat power-metabolic profiling of the Egyptian fruit bat Rousettus aegyptiacus reveals distinctive cardiac adaptations
The present study aimed to elucidate which pathways contribute to cardiometabolic adaptation in Egyptian fruit bats. Utilising cardiac tissues from Egyptian fruit bats (Rousettus aegyptiacus) and C57B...
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Aksentijevic Lab @dunjaaks.bsky.social · 07/04/2025
Exciting times! 🎉 Longstanding collaborator Prof @anjakarlstaedt.bsky.social visited our lab @qmulwhri.bsky.social today to discuss all things #cardiacmetabolism 🫀 Your insights are always invaluable, and good to explore new avenues for collaboration!
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Aksentijevic Lab @dunjaaks.bsky.social · 07/04/2025
When Mama’s scientific family from #LosAngeles #CedarsSinai come bearing the coolest gifts and become Sofia’s instant #TaylorSwift bffs! @anjakarlstaedt.bsky.social you legend 🙇🏻‍♀️🙏🏻🫶🏻
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Aksentijevic Lab @dunjaaks.bsky.social · 04/04/2025
Looking forward to hosting British Society for Cardiovascular Research Autumn Meeting (Sept 3rd, 4th) at the beautiful and historic Charterhouse Square @qmulwhri.bsky.social @qmulfmd.bsky.social . Exciting line up of speakers confirmed. Save the date! www.bscr.org/meetings/bsc...
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William Harvey Research Institute, QMUL @qmulwhri.bsky.social · 01/04/2025
Today, we celebrate the birth of William Harvey (1578–1657), the English physician who first accurately described how the heart pumps blood throughout the body. (1/3)
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