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Duncan Brownsey

@duncanbrownsey.bsky.social
127 followers 434 following 2 posts

Organic Chemist in the Buller Group, UniBern 🇨🇭 Formerly Postdoc in Waser Group (LCSO), EPFL 🇨🇭 and PhD from Derksen Group, UCalgary 🇨🇦

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Reposted by Duncan Brownsey
Waser Group @lcsolab.bsky.social · 03/05/2026
The work of @helsoleav.bsky.social @duncanbrownsey.bsky.social and Hugo Senelle, on the alcohol-directed carboamination of enynes is now published in Angewandte Chemie ! doi.org/10.1002/anie...
doi.org
Alcohol‐Directed Carboamination of Conjugated Enynes
The first general three-component intermolecular Pd-catalyzed carboamination of conjugated enynes enables the coupling of anilines and aryl triflates to produce functionalized allenic amines, utilizi...
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Reposted by Duncan Brownsey
Waser Group @lcsolab.bsky.social · 18/03/2026
The work of Josh, Tobias and Matthew on the synthesis of CF3-cycloproprenes using hypervalent iodine reagents and Cu(III) complexes is now published in Org. Lett. doi.org/10.1021/acs....
doi.org
Accessing CF3-Cyclopropenes ─ A Platform for the Synthesis of Trifluoromethylated Building Blocks
Cyclopropenes are the smallest unsaturated carbocycles. They possess exceptionally high ring strain, resulting in unique reactivity, enabling C═C bond functionalization and ring-opening transformation...
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Duncan Brownsey @duncanbrownsey.bsky.social · 11/01/2026
Very happy to share that our Pd-catalyzed method for the functionalization of cyclopropenes is now available to read in @chemicalscience.rsc.org !
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Reposted by Duncan Brownsey
Waser Group @lcsolab.bsky.social · 05/11/2025
We just achieved the first site-selective cysteine functionalization with EBX reagents! @jacs.acspublications.org pubs.acs.org/doi/10.1021/...
pubs.acs.org
Ligand-Directed Site-Selective Cysteine Bioconjugation of the KELCH Domain of KEAP1 with Hypervalent Iodine Reagents
Affinity-driven reactions have allowed chemists to perform site-selective modifications of native proteins. By combining the high cysteine chemoselectivity of hypervalent iodine-based ethynylbenziodox...
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Reposted by Duncan Brownsey
Waser Group @lcsolab.bsky.social · 01/09/2025
The preprint of the work of Josh Wu, Tobias Milzarek and Matthew Wodrich on the trifluoromethylation of Cyclopropenylbenziodoxoles is now available at ChemRxiv. This method gives access to unique fluorinated building blocks. chemrxiv.org/engage/chemr...
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Reposted by Duncan Brownsey
Waser Group @lcsolab.bsky.social · 29/08/2025
From now on until end of September we consider applications to @lcsolab.bsky.social for a regular PhD position starting earliest in September 2026! For general information, see: www.epfl.ch/labs/lcso/gr... For details on the application process, see: www.epfl.ch/labs/lcso/wp...
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