Sign in

Ray DuBois MD PhD

@duboisrn.bsky.social
416 followers 89 following 291 posts

Director of the Hollings Cancer Center @the Medical University of South Carolina: Charleston, & Executive Chair of the Mark Foundation for Cancer Research. Tweets and opinions are mine

PostsRepliesMedia
Ray DuBois MD PhD @duboisrn.bsky.social · 07/10/2026
It Can Keep #Cancer in Remission. BUT, No One Talking About It? www.nytimes.com/2026/10/06/w...
nytimes.com
It Can Keep Cancer in Remission. Why Is No One Talking About It?
Despite mounting evidence that exercise programs can improve cancer outcomes, access to them remains limited.
000
Ray DuBois MD PhD @duboisrn.bsky.social · 05/10/2026
Nearly 200 people isolated after lab worker in #Russia dies of #plague: www.newscientist.com/article/2592...
newscientist.com
Nearly 200 people isolated after lab worker in Russia dies of plague | New Scientist
A lab accident is said to have led to the death of a woman from pneumonic plague in the Irkutsk region of Siberia, leading to nearly 200 possible contacts being put under observation
000
Ray DuBois MD PhD @duboisrn.bsky.social · 02/10/2026
Ned #Sharpless joins #Hatteras, as Andrew Witty returns to the VC firm as chairman - endpoints.news/ned-sharples...
endpoints.news
Ned Sharpless joins Hatteras, as Andrew Witty returns to the VC firm as chairman
Hatteras Venture Partners names ex-NCI director Ned Sharpless as MD and Andrew Witty as chairman, while raising a $100M second opportunities fund.
000
Ray DuBois MD PhD @duboisrn.bsky.social · 01/10/2026
Clues to Why a Breakthrough #Pancreatic #Cancer Drug Eventually Stops Working: www.nytimes.com/2026/09/30/s...
nytimes.com
Clues to Why a Breakthrough Pancreatic Cancer Drug Eventually Stops Working
Researchers are asking why patients, like former Senator Ben Sasse, inevitably develop resistance to the drug daraxonrasib.
010
Ray DuBois MD PhD @duboisrn.bsky.social · 29/09/2026
Rare Inherited Genetic #Mutation Is One of Strongest Indicators Yet for #LungCancer #Risk: hms.harvard.edu/news/rare-in...
hms.harvard.edu
001
Ray DuBois MD PhD @duboisrn.bsky.social · 29/09/2026
#ctDNA Assay Shows High Specificity for Post-Transplant #LiverCancer Recurrence: www.cancernetwork.com/view/ctdna-a...
cancernetwork.com
ctDNA Assay Shows High Specificity for Post-Transplant Liver Cancer Recurrence | CancerNetwork
A personalized ctDNA assay demonstrated 100% specificity but limited sensitivity for detecting recurrence after liver transplantation in HCC and CCA.
000
Ray DuBois MD PhD @duboisrn.bsky.social · 29/09/2026
Clinical Uses of Common #Genetic Variants Associated with Common #Diseases: #NEJM www.nejm.org/doi/full/10....
nejm.org
Clinical Uses of Common Genetic Variants Associated with Common Diseases | NEJM
Twenty-five years after the draft of the human genome sequence, genomics has revolutionized many areas of biology, the diagnosis of familial and early-onset diseases, and the development of targete...
000
Ray DuBois MD PhD @duboisrn.bsky.social · 25/09/2026
FDA Approves #Lirafugratinib for Previously Treated #FGFR2-Altered #Cholangiocarcinoma: www.pharmacytimes.com/view/fda-app...
pharmacytimes.com
FDA Approves Lirafugratinib for Previously Treated FGFR2-Altered Cholangiocarcinoma | Pharmacy Times
The FDA approved lirafugratinib for adults with previously treated, advanced cholangiocarcinoma harboring an FGFR2 fusion or other rearrangement after the REFOCUS trial showed a 46% ORR.
000
Reposted by Ray DuBois MD PhD
HHMI @hhmi-science.bsky.social · 23/09/2026
ERG, activated by gene fusion in ~50% of prostate cancers in men w/European ancestry, was long considered undruggable. Now #HHMIInvestigator Arul Chinnaiyan & co have developed a molecule probe that binds to ERG, killing cancer cells & preventing tissue invasion in preclinical models bit.ly/46wb7bv
Arul Chinnaiyan in a suite in his office
031
Ray DuBois MD PhD @duboisrn.bsky.social · 23/09/2026
U.S. Cancer Mortality Declined 35% Since 1991, AACR Report Shows: www.aacr.org/about-the-aa...
aacr.org
AACR Releases Annual Cancer Progress Report Highlighting Promising Advances for Patients
This comprehensive report provides current data on cancer incidence, mortality, and survivorship and outlines how federal investments in cancer research are improving and saving lives.
000
Ray DuBois MD PhD @duboisrn.bsky.social · 14/09/2026
Rally for Medical Research: vimeo.com/1226080336/b...
vimeo.com
Rally For Medical Research - Current Version 9/11/26
This is "Rally For Medical Research - Current Version 9/11/26" by AACR Events on Vimeo, the home for high quality videos and the people who love them.
000
Ray DuBois MD PhD @duboisrn.bsky.social · 11/09/2026
Sunrise this morning (September 11, 2026) over Colonial Lake in Charleston, SC. Remembering those lost on 9/11/2001
010
Ray DuBois MD PhD @duboisrn.bsky.social · 11/09/2026
Twenty-five years ago, I was in Seoul, South Korea, participating in an #AACR meeting held in partnership with the Korean Cancer Association (#KCA) on Molecular Mechanisms of Gastrointestinal Cancer Development and Its Clinical Implications. Remembering Countless individuals whose lives were lost.
000
Ray DuBois MD PhD @duboisrn.bsky.social · 10/09/2026
A blood-based test for detection of advanced #adenomas and #colorectalcancer (DENEB): a multicentre diagnostic accuracy study - The Lancet www.thelancet.com/journals/lan...
thelancet.com
A blood-based test for detection of advanced adenomas and colorectal cancer (DENEB): a multicentre diagnostic accuracy study
These findings provide the rationale for advancing this assay into large-scale prospective studies to determine its performance, clinical utility, and potential role within population-based screening ...
000
Ray DuBois MD PhD @duboisrn.bsky.social · 10/09/2026
‘Shocking’ proportion of women #unscreened for #cervical #cancer says @muschollings scientist K. Sonawane: www.healio.com/news/hematol...
healio.com
‘Truly shocking’: Nearly one-third of young women unscreened for cervical cancer
The proportion of U.S. women who have never been screened for cervical cancer increased at a “troubling” rate over the past couple decades, according to researchers.As recently as a few ye...
000
Ray DuBois MD PhD @duboisrn.bsky.social · 04/09/2026
#Alcohol-Attributable #Cancer Mortality Has Increased Significantly in the U.S. www.healthday.com/healthpro-ne...
healthday.com
Alcohol-Attributable Cancer Mortality Has Increased Significantly in the U.S.
THURSDAY, Sept. 3, 2026 (HealthDay News) -- Alcohol-attributable cancer mortality has increased in the United States, with mortality rates higher in men and tho
100
Ray DuBois MD PhD @duboisrn.bsky.social · 01/09/2026
Update regarding advanced #lung #cancer patients and treatment: www.southcarolinapublicradio.org/show/health-...
southcarolinapublicradio.org
Research regarding advanced lung cancer patients and treatment
This week, Bobbi Conner talks with MUSC's Dr. Gerard Silvestri about research indicating that many advanced lung cancer patients never receive treatment.
000
Ray DuBois MD PhD @duboisrn.bsky.social · 14/08/2026
Very interesting survival data in patients with triple negative #breastcancer: jamanetwork.com/journals/jam...
jamanetwork.com
Tissue-Free vs Tumor-Informed Circulating Tumor DNA Assays in Early Triple Negative Breast Cancer
This prognostic study compares tissue-free circulating tumor DNA analysis to tissue-free assay with tumor-informed assay results for estimating recurrence in patients with triple negative breast cance...
000
Ray DuBois MD PhD @duboisrn.bsky.social · 12/08/2026
Scientists Uncover Cellular #Mechanism Driving Both Rare Childhood #Dementia and #Alzheimer’s Disease today.ucsd.edu/story/scient...
today.ucsd.edu
Scientists Uncover Cellular Mechanism Driving Both Rare Childhood Dementia and Alzheimer’s Disease
UC San Diego researchers have found a
010
Ray DuBois MD PhD @duboisrn.bsky.social · 11/08/2026
Great review on #liquid #biopsies for #cancer: jamanetwork.com/journals/jam...
jamanetwork.com
Liquid Biopsies for Cancer
This narrative review examines how liquid biopsy, particularly circulating tumor DNA, can guide treatment decisions by helping clinicians monitor cancer progression, detect minimal residual cancer, an...
000
Ray DuBois MD PhD @duboisrn.bsky.social · 06/08/2026
#Viral #Mimicry by Repeats Mediates Evolutionary Trade-Offs in #Cancer-Immune Coevolution: aacrjournals.org/cancerdiscov...
aacrjournals.org
Viral Mimicry by Repeats Mediates Evolutionary Trade-Offs in Cancer-Immune Coevolution
Summary:. During cancer evolution, derepressed repetitive elements (REs) can trigger innate immune responses via “viral mimicry,” imposing selective immune pressure on emerging tumor cells. We propose...
000
Ray DuBois MD PhD @duboisrn.bsky.social · 04/08/2026
Do #GLP-1 agonists reduce #cancer risk? aacrjournals.org/cancerpreven...
aacrjournals.org
Appetite, Obesity, Metabolism, and Malignancy: Do Incretin-Mimetic Drugs Reduce Cancer Risk?
Abstract. Obesity is associated with increased risk of at least 13 adult cancer types and is the second most common cause of cancer (after tobacco) in many populations. Uncertainty about the extent to...
000
Ray DuBois MD PhD @duboisrn.bsky.social · 29/07/2026
My paternal ancestors' home country, #France, is on #fire:
000
Ray DuBois MD PhD @duboisrn.bsky.social · 23/07/2026
Among participants with muscle-invasive #bladder #cancer eligible for cisplatin-based chemotherapy, perioperative enfortumab vedotin–pembrolizumab led to significantly better overall survival outcomes and much better pathological complete #response: www.nejm.org/doi/full/10....
nejm.org
Enfortumab Vedotin and Pembrolizumab in Cisplatin-Eligible Bladder Cancer | NEJM
Neoadjuvant cisplatin-based chemotherapy is a standard therapy for muscle-invasive bladder cancer. The efficacy and safety of neoadjuvant and adjuvant (perioperative) enfortumab vedotin–pembrolizum...
010
Ray DuBois MD PhD @duboisrn.bsky.social · 15/07/2026
How regulatory cells that #shield against inflammatory #bowel #disease: www.nih.gov/news-events/...
nih.gov
NIH researchers identify regulatory cells that shield against inflammatory bowel disease
Discovery opens the door for improved diagnoses and treatments.
000
Ray DuBois MD PhD @duboisrn.bsky.social · 09/07/2026
#Autonomous biomedical #research with an artificial intelligence (#AI) agent: www.science.org/doi/10.1126/...
science.org
Autonomous biomedical research with an artificial intelligence agent
Biomedical research is increasingly constrained by repetitive, fragmented workflows that slow discovery. We introduce Biomni, a general-purpose biomedical artificial intelligence agent that autonomous...
010
Ray DuBois MD PhD @duboisrn.bsky.social · 09/07/2026
#Aging in not linear, there are 3 waves of aging:
000
Ray DuBois MD PhD @duboisrn.bsky.social · 09/07/2026
#IDH1-mutant vaccine for #astrocytoma launched: www.nature.com/articles/s43...
nature.com
IDH1-mutant vaccine in newly diagnosed astrocytoma: final analysis of the multicenter, single-arm, open-label, first-in-human phase 1 NOA16 trial - Nature Cancer
In the multicenter, single-arm, open-label, first-in-human phase 1 NOA16 trial, Platten and colleagues report the long-term clinical and immunological follow-up outcomes of a vaccine targeting mutant ...
020
Ray DuBois MD PhD @duboisrn.bsky.social · 08/06/2026
The care that carried her through her #cancer journey @muschollings hollingscancercenter.musc.edu/content-hub/...
hollingscancercenter.musc.edu
The care that carried her
Betty Frasier has lived through four cancer diagnoses, but what she thinks of most is the relationships that have carried her through treatment.
000
Ray DuBois MD PhD @duboisrn.bsky.social · 05/06/2026
I want to thank both the Cancer Research UK and the American Cancer Society for this wonderful recognition at their annual #Cancer #Prevention meeting in Atlanta this week: news.cancerresearchuk.org/2026/06/03/p...
news.cancerresearchuk.org
“Preventing a cancer from ever developing is one of the greatest contributions we can make” – Raymond DuBois wins Outstanding Achievement in Cancer Prevention Research Award - Cancer Research UK - Can...
We caught up with Raymond N. DuBois fresh from his presentation at The Cancer Prevention Research Conference…
000
Ray DuBois MD PhD @duboisrn.bsky.social · 04/06/2026
Interesting Ted Talk by a scientist at #MUSC in Charleston, SC: www.youtube.com/watch?app=de...
youtube.com
Curiosity is the cure: what if we could end type 1 diabetes | Dr. Leonardo Ferreira | TEDxCharleston
YouTube video by TEDx Talks
000
Ray DuBois MD PhD @duboisrn.bsky.social · 29/05/2026
NO CANCER RESEARCH=NO NEW CANCER CURES: www.aacr.org/patients-car...
aacr.org
National Cancer Research Month
May is National Cancer Research Month. Thanks to research, more than 18.6 million people in the U.S. are cancer survivors.
000
Ray DuBois MD PhD @duboisrn.bsky.social · 29/05/2026
#Heidelberg University partners with #Harvard! www.uni-heidelberg.de/en/newsroom/...
uni-heidelberg.de
Partnership Between Heidelberg and Harvard: Implementation of Initial Projects Begins - Heidelberg University
010
Ray DuBois MD PhD @duboisrn.bsky.social · 28/05/2026
Great job opportunity at #Hollings #Cancer Center as Co-Director of Cancer #Bioinformatics in the HCC Data Science Shared Resource: lnkd.in/evnk_gmc
lnkd.in
LinkedIn
This link will take you to a page that’s not on LinkedIn
010
Ray DuBois MD PhD @duboisrn.bsky.social · 21/05/2026
CLINICAL TRIALS ARE IMPORTANT because they translate scientific discoveries into better patient care. They determine whether new therapies, prevention strategies, screening approaches, and diagnostic tools are safe and effective in people.
010
Ray DuBois MD PhD @duboisrn.bsky.social · 21/05/2026
hms.harvard.edu/news/new-way...
hms.harvard.edu
A New Way To Think About Age and Cancer Genetics
Study finds only some mutations believed to cause cancer actually do — and age provides a clue
010
Ray DuBois MD PhD @duboisrn.bsky.social · 18/05/2026
#Sean_Parker-backed #cancer institute has a new commercialization plan after CEO change: www.bizjournals.com/sanfrancisco...
bizjournals.com
Sean Parker-backed cancer institute has a new commercialization plan after CEO change - San Francisco Business Times
The Parker Institute for Cancer Immunotherapy is accelerating cancer research and commercialization under new CEO Karen Knudsen. The Sean Parker-backed PCI has cancer vaccines in its targets.
010
Ray DuBois MD PhD @duboisrn.bsky.social · 08/05/2026
Fabricated references: a new threat to editorial integrity: www.thelancet.com/journals/lan...
thelancet.com
Fabricated references: a new threat to editorial integrity
In this issue of The Lancet, Topaz and colleagues1 report the first systematic evaluation of the authenticity of references. The authors initially identified 125 615 773 references from 2 471 758 pape...
010
Ray DuBois MD PhD @duboisrn.bsky.social · 08/05/2026
#Epigenetic Fingerprints Show Link Between #Early-Onset #CRC and #Herbicide Exposure: www.cancertherapyadvisor.com/news/epigene...
cancertherapyadvisor.com
Epigenetic Fingerprints Show Link Between Early-Onset CRC and Herbicide Exposure
Investigators constructed weighted methylation risk scores to pinpoint specific risk factors associated with early-onset CRC versus late-onset CRC.
010
Ray DuBois MD PhD @duboisrn.bsky.social · 07/05/2026
Breakthrough in early #detection of #cancer: x.com/TheLeadCNN/s...
x.com
000
Ray DuBois MD PhD @duboisrn.bsky.social · 07/05/2026
#AI detects #pancreatic #cancer 3 years before diagnosis: #Mayo @muschollings www.beckersoncology.com/oncology/ai-...
beckersoncology.com
AI detects pancreatic cancer 3 years before diagnosis: Mayo Clinic - Becker's Oncology
An AI model developed by researchers at Rochester, Minn.-based Mayo Clinic detected pancreatic cancer on abdominal CT scans taken up to three years before clinical diagnosis, according to a study publ...
000
Ray DuBois MD PhD @duboisrn.bsky.social · 06/05/2026
Non-invasive #profiling of the #tumour #microenvironment (#TME) with spatial ecotypes: www.nature.com/articles/s41...
nature.com
Non-invasive profiling of the tumour microenvironment with spatial ecotypes - Nature
Multimodal machine learning reveals that tumour microenvironments can be decomposed into spatially organized multicellular ecosystems, termed spatial ecotypes, that can be accessed non-invasively via ...
000
Ray DuBois MD PhD @duboisrn.bsky.social · 18/04/2026
Tackling the #complexity of #cancer with #generative AI models: Cell www.cell.com/cell/fulltex...
cell.com
Tackling the complexity of cancer with generative models
This perspective summarizes the ways in which artificial intelligence has already impacted cancer detection, understanding, and intervention, then posits that generative models are a key technology fo...
020
Ray DuBois MD PhD @duboisrn.bsky.social · 09/04/2026
#Genetic predictors of #GLP1 receptor #agonist weight loss and side effects: www.nature.com/articles/s41...
nature.com
Genetic predictors of GLP1 receptor agonist weight loss and side effects - Nature
Identification of genetic variants associated with the efficacy and side effects of GLP1 medications could underpin development of precision medicine approaches in the treatment of obesity.
010
Ray DuBois MD PhD @duboisrn.bsky.social · 26/03/2026
Stunning new images of #Saturn just released:
000
Ray DuBois MD PhD @duboisrn.bsky.social · 26/03/2026
Engineering #NK and #T_cells with #metabolite-sensing receptors to target #solid #tumors: www.nature.com/articles/s41...
nature.com
Engineering NK and T cells with metabolite-sensing receptors to target solid tumors - Nature Immunology
Here the authors use CRISPR activation screens to identify metabolite-sensing receptors that affect lymphocyte targeting and infiltration of tumors and engineer CAR T and CAR NK cells with these recep...
010
Ray DuBois MD PhD @duboisrn.bsky.social · 26/03/2026
A first-in-class #KRAS G12D-targeted protein degrader active in #lung and #pancreatic #cancer patients: pubmed.ncbi.nlm.nih.gov/41879829/
pubmed.ncbi.nlm.nih.gov
Setidegrasib in Advanced Non-Small-Cell Lung Cancer and Pancreatic Cancer - PubMed
Setidegrasib was associated with antitumor activity and a low incidence of treatment discontinuation due to adverse events in patients with previously treated advanced <i>KRAS</i> p.G12D-mutated NSCLC or pancreatic ductal adenocarcinoma. (Funded by Astellas Pharma; ClinicalTrials.gov number, NCT0538 …
000
Reposted by Ray DuBois MD PhD
The Mark Foundation for Cancer Research @themarkfdn.bsky.social · 24/03/2026
🏆This year, we’re thrilled to have Nobel Laureate William Kaelin Jr., MD, delivering our keynote address. Incredible to get insights on the frontiers of research from a true leader in the field! #MarkSymposium
051
Ray DuBois MD PhD @duboisrn.bsky.social · 24/03/2026
#UCLA researchers (Dr. Chen) engineer #CAR_T cells to target hard-to-treat solid #tumors (like brain cancer): stemcell.ucla.edu/news/ucla-re...
stemcell.ucla.edu
UCLA researchers engineer CAR-T cells to target hard-to-treat solid tumors
UCLA scientists have developed a next-generation CAR-T cell therapy that can overcome the immunosuppressive tumor microenvironment, a protective shield that tumors use to weaken immune cells, block th...
000
Ray DuBois MD PhD @duboisrn.bsky.social · 20/03/2026
#FOXCHASE brings on a new leader: www.foxchase.org/news/temple-...
foxchase.org
Temple Health Appoints Robert A. Winn, MD, as Cancer Center Director for Fox Chase Cancer Center
Temple Health today announced the appointment of Robert A. Winn, MD, as the next Cancer Center Director for Fox Chase Cancer Center, marking a defining moment that will shape the future of one of the ...
000