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Alt NIH Bluesky 🧪 @altnih4science.bsky.social · 01/03/2025

Francis Collins, longtime NIH director with bipartisan bona fides*, retires as of yesterday. He returned to NIH in 2023 to focus on research in his own lab, in the NIH in-house intramural research campus. His letter seems to imply he wasn’t ready to leave. NIH is being torn down. 1/🧪 #academicsky

Statement by Francis Collins, MD. PhD
March 1, 2025 Yesterday I notified NIH Acting Director Matt Memoli, MD of my retirement from the federal government.
effective February 28, 2025. The National Institutes of Health is the world's foremost medical research institution. It has been rightfully called the "crown jewel" of the federal government for decades. It has been the greatest honor of my life to be part of this institution in various roles
over the last four decades. In the 1980s, NIH supported my work at the University of Michigan through a peer-reviewed grant. That led
to the identification of the gene for cystic fibrosis. Thirty years later that has led to an almost miraculous treatment that allows most kids with cystic fibrosis to
look forward to an almost normal life span. I was recruited to NIH in 1993 to lead the Human Genome Project - an extraordinarily bold initiative to read out the three billion letters of the human DNA instruction book. Funded by the U.S. Congress, the project completed its work -- two years ahead of schedule, and $400 million under budget. The success of the project, and the commitment to share all of the data rapidly and freely, has revolutionized every aspect
of human biomedical research and medical practice. Subsequently I was honored to be asked to serve as the Director of the National Institutes of Health. I had the chance to serve three Presidents - Barack Obama, Donald Trump, and Joseph Biden. I also had the opportunity to work regularly
with members of Congress in both parties. I loved those interactions and
relationships.
Throughout that time, investment

relieving
human suffering, and
contributing
substantially to the U.S. economy.
That consistent
support
made
possible
bold
new projects
in regenerative medicine, brain science, precision health, cancer, and solutions for opioid addiction, to name just
a few. When the worst pandemic in more than a century arose in 2020, it was my job as Director of NIH to pull together partnerships with the FDA, academia, and the private sector to produce what only America's unparalleled biomedical sector could have: COVID vaccines in just 11 months, a staggering medical
achievement that saved over three million lives in the
U.S.alone. After a stint in the White House as the President's Acting Science Advisor, where I had the chance to organize a major initiative to eliminate hepatitis C in the United States, i returned to the intramural research program of the National Human Genome Research Institute in 2023. There I have been overseeing a research laboratory of a dozen highly talented and visionary scientists who are providing new insights into the causes and possible means of prevention of type 2 diabetes, as well as seeking a gene therapy cure for one of the world's rarest diseases - progeria, a
premature aging disorder. NIH is the largest supporter of biomedical research in the world. It is the main piston of a biomedical discovery engine that is the envy of the globe. Yet it is not a household name. It should be. NIH supports everything from basic science to clinical trials,
providing the foundation of many breakthroughs. When you hear about patients surviving stage 4 cancer because of immunotherapy, that was based on NIH research over many decades. When you hear about
sickle cell disease being cured because of CRISPR

$gene editing, that was built on many years of research supported by NIH. It has also been the largest supporter of global health research in the world, winning us many friends and colleagues from across the globe. I have loved being employed by this extraordinary, life-giving institution for 32 years. I will continue to devote my life in other ways to seeking knowledge and enhancing health, to healing disease and reducing suffering, and to doing what I can to bring together our fractured communities around the shared values of love, truth, goodness, and faith. As I depart NIH, I want to express my gratitude and love for the men and women with whom I have worked side-by-side for so many years. They are individuals of extraordinary intellect and integrity, selfless and hard-working, generous and compassionate. They personify excellence in every way, and they deserve the utmost respect and support of all Americans.$

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