🚨 New preprint 🚨
In cirrhosis, oral👄 microbes (Veillonella, Streptococcus) translocate ↘️ gut, carry a collagenase-like enzyme (prtC), disrupt⛓️💥 the intestinal barrier & ⬆️ hepatic fibrosis 🧬
www.biorxiv.org/content/10.1...
biorxiv.org
Microbial oral-gut translocation in advanced chronic liver disease is linked to exacerbation of intestinal barrier dysfunction and hepatic fibrosis
While microbiome perturbations are associated with advanced chronic liver disease (ACLD), microbial disease mechanisms are poorly understood. Using multi-omics analyses of paired saliva and faecal sam...