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Dr. Shaun Sanders, she/her/hers

@drssfs.bsky.social
585 followers 483 following 2 posts

Assistant Professor @ UofGuelph MCB. Neuroscientist and foodie. She/her.

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Reposted by Dr. Shaun Sanders, she/her/hers
DMartin @drddom.bsky.social · 06/08/2026
So happy to share our latest review on how post-translational modifications of SQSTM1, including S-acylation, regulate autophagy in neurodegeneration. www.tandfonline.com/doi/full/10....
tandfonline.com
Molecular switches of SQSTM1: the impact of post-translational modifications on autophagy and neurodegeneration
SQSTM1/p62 (sequestosome 1) is an important receptor protein involved in many cellular signaling processes, including macroautophagy/autophagy. It is a molecular hub for cellular homeostasis and ce...
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Reposted by Dr. Shaun Sanders, she/her/hers
DMartin @drddom.bsky.social · 06/08/2026
This was led by former MSc Fatima Abrar in my lab. After publishing (after getting scooped) our work on S-acylation of SQSTM1/p62 in Huntington Disease, Fatima wanted to her work into context of all PTMs. FYI, Fatima is looking for a PhD position in Germany. Please DM me to connect you with Fatima.
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DMartin @drddom.bsky.social · 05/07/2026
Excited to share we identified an S-acylation motif & used it to develop a new S-acylation prediction program! @drssfs.bsky.social
biorxiv.org
SAPPTree: Identification of an S-Acylation Motif Drives a Novel S-Acylation Prediction Program
S-acylation, the reversible addition of fatty acids to proteins, has emerged as an abundant post-translational modification that drives protein localization and function. With no known consensus seque...
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Reposted by Dr. Shaun Sanders, she/her/hers
DMartin @drddom.bsky.social · 08/06/2026
What an incredible turnout for @alscanada.bsky.social #WalkToEndALS at @uwaterloo.ca! 250-300 people came to raise funds & awareness for ALS. We hit our target & then some! Thank you to everyone who came out & @waterloosci for all your support! alscanadawalktoendals.als.ca/ontario2026/...
Group photo of the NeurdyPhagy Lab and family standing outside. A goofy looking ginger (me) is taking a selfie with everyone in the background). Everyone is wearing tshirts with the Walk to End ALS logos. Also, my beautiful chunky bulldog Ruby is staring up at me lovingly.
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Reposted by Dr. Shaun Sanders, she/her/hers
DMartin @drddom.bsky.social · 06/06/2026
Today marks the first day for the Walks to End ALS & ours is happening today! Please consider donating here. Or if you're in the Waterloo area come join us! We'll be at the @uwaterloo.ca alscanadawalktoendals.als.ca/ontario2026/...
alscanadawalktoendals.als.ca
2026 Walk to End ALS - Ontario : Kitchener/Waterloo
REGISTER SEARCH Participants & Teams Date: Saturday, June 6thLocation: University of WaterlooAddress: 200 University Ave W, Waterloo, ON N2L 3G1Contact: info@walktoendals.ca Registration Time: 10:00 A...
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Reposted by Dr. Shaun Sanders, she/her/hers
DMartin @drddom.bsky.social · 01/06/2026
Happy to announce (albeit delayed) that @uwaterloo.ca @waterloosci.bsky.social & the NeurdyPhagy Lab are hosting the local #WalkToEndALS this Saturday June 6th. Please join us or consider making a donation here: alscanadawalktoendals.als.ca/ontario2026/...
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Reposted by Dr. Shaun Sanders, she/her/hers
DMartin @drddom.bsky.social · 08/04/2026
Very excited to share our preprint showing S-acylation (aka Palmitoylation) of TDP-43, VCP, SQSTM1, FUS & C9Orf72 in Huntington Disease (HD), Amyotrophic Lateral Sclerosis (ALS), & Multisystem Proteinopathy (MSP). This tour de force was led by @firyalrphd.bsky.social! www.biorxiv.org/content/10.6...
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SfN Journals @sfnjournals.bsky.social · 20/03/2026
#JNeurosci Review | Perry and Martin discuss the links between ALS and Huntington Disease, highlighting two proteins that potentially contribute to the onset and progression of these neurodegenerative diseases. doi.org/10.1523/JNEUROSCI.0263-25.2…
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Reposted by Dr. Shaun Sanders, she/her/hers
DMartin @drddom.bsky.social · 11/03/2026
Thrilled to share our recent review in @sfnjournals.bsky.social ALS and Huntington Disease: Unraveling the Connections between TDP-43 and Huntingtin. Here we discuss links between HD & ALS. Review & cover art come from the multitalented MSc student @cailyncreative.bsky.social tinyurl.com/57y6hjrd
Screenshot from the JNeursci Webpage showing the cover art.

This artwork portrays a fictional person with amyotrophic lateral sclerosis (ALS). Framing their face is a network of neurons that highlights two motor neurons. One neuron extending from the mouth down to the hands symbolizes two of the major motor functions affected by ALS: bulbar and spinal. The second neuron forms from a single tear that represents the fear those with the disease endure. As this neuron extends to the hands, the connection is severed, symbolizing both the disconnect between the brain and muscles caused by neuron death and the determination of those affected not to be defined by their disease. The bound hands emphasize the physical constraints imposed by ALS while the distance between the hands conveys perseverance. Among the wildflowers shown is the blue cornflower, an emblematic symbol of ALS representing hope and resilience. See the review article by Cailyn Perry and Dale Martin for information on mechanistic links between ALS and Huntington's disease. Cover image: Cailyn Perry.
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Reposted by Dr. Shaun Sanders, she/her/hers
DMartin @drddom.bsky.social · 02/02/2026
If you want to see our research promoted like it's a sports event go to the 1h13min mark: www.upliftingathletes.org/young-invest... It was really cool to hear our work described this way.
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DMartin @drddom.bsky.social · 11/09/2025
Save the Date for the next @csmb-scbm.bsky.social meeting: Membrane Proteins in Health & Diseases April 8-12, 2026 in beautiful Banff! Looks like there's something for everyone. event.fourwaves.com/2026csmb/pages
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Joey Bernhardt @joeybernhardt.bsky.social · 08/07/2025
✨ The Bernhardt Lab at the University of Guelph is recruiting graduate students for 2026! Join us! We have several fully funded grad positions available ✨ Please spread the word! www.bernhardtlab.org/join-us #CSEE2025
A blue poster describing opportunities to join the Bernhardt Lab -- for more information please see https://www.bernhardtlab.org/join-us
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Reposted by Dr. Shaun Sanders, she/her/hers
DMartin @drddom.bsky.social · 21/05/2025
Had the privilege to attend the Satellite meeting for Future Leaders In Canadian Brain Research held by @braincanada.bsky.social Got to hear updates from some amazing early career researchers!
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Reposted by Dr. Shaun Sanders, she/her/hers
DMartin @drddom.bsky.social · 25/04/2025
All days should be WFH days according to Ruby. Although she wants more pets and less proofing of manuscripts & grading.
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Reposted by Dr. Shaun Sanders, she/her/hers
DMartin @drddom.bsky.social · 10/04/2025
New science couple unlock. Today @drssfs.bsky.social & I had papers accepted! Shaun happens to also be a co-author on the paper from my lab. So, double congrats to her. Also, my paper is my greatest academic albatross. So, I'm pleased to have this out!
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Reposted by Dr. Shaun Sanders, she/her/hers
Cezar Khursigara @cmkhursigara.bsky.social · 29/03/2025
The Department of Molecular and Cellular Biology at the University of Guelph is at it again! Continuing our cluster hires with tenure-track Assistant Professor positions in Immunology and Virology (1 position each)! careers.uoguelph.ca/job/Guelph-A... careers.uoguelph.ca/job/Guelph-A...
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DMartin @drddom.bsky.social · 11/03/2025
Hey all you lipid freaks, join me & other lipid obsessed people talk about protein lipidation! If you've never attended, first drink is on me or @pjenkinslab.bsky.social Roles and regulation of protein lipidation in health and disease 27-29 August 2025 Exeter College, Oxford @biochemsoc.bsky.social
https://www.eventsforce.net/biochemsoc/frontend/reg/thome.csp?pageID=121401&eventID=227&CSPCHD=001001000000IrVw71GSKcqgqTVkzjZlSk4daZZ3dB6xK_iLWh
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DMartin @drddom.bsky.social · 16/12/2024
Was quite the experience to visit our old postdoc department being on the other side of the lunch table during the career session & having trainees ask us about our career paths. Thanks again to Gareth Thomas for inviting us. @drssfs.bsky.social followed up with an excellent talk of course.
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Reposted by Dr. Shaun Sanders, she/her/hers
DMartin @drddom.bsky.social · 07/12/2024
The NeurdyPhagy Lab is in Montreal talking all about palmitoylation in ALS MND. Stop by our posters & say hi. @jesuisyasmeena.bsky.social @cailyncreative.bsky.social
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Reposted by Dr. Shaun Sanders, she/her/hers
DMartin @drddom.bsky.social · 08/10/2023
Vacation Ruby. It's been a ruff day (we got scooped on a big story), but Ruby always makes it better (for context, we had charcuterie for dinner & two of those pics are of her trying to go under the table).
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