Reposted by Dr. Shaun Sanders, she/her/hers
So happy to share our latest review on how post-translational modifications of SQSTM1, including S-acylation, regulate autophagy in neurodegeneration. www.tandfonline.com/doi/full/10....
tandfonline.com
Molecular switches of SQSTM1: the impact of post-translational modifications on autophagy and neurodegeneration
SQSTM1/p62 (sequestosome 1) is an important receptor protein involved in many cellular signaling processes, including macroautophagy/autophagy. It is a molecular hub for cellular homeostasis and ce...