This week, we will discuss why a large registry cohort was needed to move past decades of scattered case reports and clarify the true risk of hydralazine‑associated vasculitis. When rare events hide i...

Next-generation sequencing (NGS) is transforming how we diagnose autosomal dominant polycystic kidney disease (ADPKD), particularly in atypical or unclear cases. While most diagnoses rely on imaging and family history, genetic testing offers critical insights into prognosis, mutation type, and family planning. This evolving tool helps unravel diagnostic uncertainty and supports more precise, personalized care in ADPKD.

Next-generation sequencing (NGS) is transforming how we diagnose autosomal dominant polycystic kidney disease (ADPKD), particularly in atypical or unclear cases. While most diagnoses rely on imaging and family history, genetic testing offers critical insights into prognosis, mutation type, and family planning. This evolving tool helps unravel diagnostic uncertainty and supports more precise, personalized care in ADPKD.

2025 was rich in successful stories. Here are the top 10 that impressed our audience.

In patients with dialysis-dependent acute kidney injury, a conservative dialysis strategy was evaluated in the LIBERATE-D trial. Could less be more? Join the discussion in #NephJC, but first, check ou...

This week, we will discuss whether less is more when it comes to discontinuing dialysis in patients with AKI and a chance to recover.

Bringing concepts of tolerance induction to clinical reality through advanced-phase randomized controlled trials (RCTs) has been an Achilles heel in organ transplantation since Owen1 and Billingham et...

This week, we will discuss the clinical significance of eGFRdiff, the difference in eGFRcys (cystatin C) and eGFRcr (creatinine).

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This week, we will discuss a pediatric nephrology trial: is tacrolimus superior to MMF in FRNS and SDNS?