iiinova — where your digital self keeps evolving

Dr Marie Spreckley @drmariespreckley.bsky.social · 01/06/2026

So brilliant to work on this with you! 🙂

Reposted by Dr Marie Spreckley

Cara Ruggiero, PhD, RD, LDN @cararuggiero.bsky.social · 01/06/2026

📣 Incretin-based therapies are changing obesity treatment, but who is able to benefit? Another brilliant and impactful article led by @drmariespreckley.bsky.social ✨ Thank you to Dr Adrian Brown for supporting this work. lnkd.in/ehH8Uw_t @imsepidemiology.bsky.social @ims-mrl.bsky.social

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Reposted by Dr Marie Spreckley

IMS Epidemiology, University of Cambridge @imsepidemiology.bsky.social · 17/05/2026

@imsepidemiology.bsky.social’s @drmariespreckley.bsky.social was a keynote panellist at @sbm.org’s 47th Annual Meeting. She examined evolving definitions of success in obesity treatment with incretin-based therapies, highlighting quality of life, sustainability, & patient-centred outcomes.

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Dr Marie Spreckley @drmariespreckley.bsky.social · 14/05/2026

Delighted to receive this nomination. Thank you! 🙂

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Dr Marie Spreckley @drmariespreckley.bsky.social · 26/04/2026

Fantastic to join the Keynote Panel at the 47th Annual Meeting of the Society of Behavioural Medicine in Chicago ✨ @imsepidemiology.bsky.social

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Dr Marie Spreckley @drmariespreckley.bsky.social · 24/04/2026

If you’re in Chicago, we’d love to see you at the closing keynote. I’ll be speaking on: “New Tools, Old Questions: How Should We Define Success in Weight and Health?” @imsepidemiology.bsky.social

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Reposted by Dr Marie Spreckley

Cara Ruggiero, PhD, RD, LDN @cararuggiero.bsky.social · 20/04/2026

This was such a great collaboration with @drmariespreckley.bsky.social, Dr Adrian Brown, and Dr Nikki Davis, published in @thelancetendo.bsky.social !

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Dr Marie Spreckley @drmariespreckley.bsky.social · 20/04/2026

Delighted to see our latest publication in The Lancet Diabetes & Endocrinology: “Prioritising nutrition alongside paediatric obesity management medications”Congratulations to @cararuggiero.bsky.social for leading this important piece: www.thelancet.com/journals/lan...

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Dr Marie Spreckley @drmariespreckley.bsky.social · 13/04/2026

Delighted to contribute to the latest Financial Times feature on the growing consumerisation of GLP-1 therapies and the future of obesity treatment. It is important to remember that they remain medical interventions requiring appropriate clinical oversight, support, and equitable access.

ft.com

Weight-loss drugs and Mars bars: Novo Nordisk’s comeback bid

The maker of Wegovy and Ozempic wants to learn lessons from consumer groups to crack the US market

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Reposted by Dr Marie Spreckley

IMS Epidemiology, University of Cambridge @imsepidemiology.bsky.social · 09/04/2026

Nipping at the heels of GLP-1 weight-loss drugs is the growing concern the pounds shed will be rapidly regained. "You don't want to have longer-term unintended consequences, like frailty and muscle loss. We don't want to replace one health concern with another." Read – buff.ly/OTpSvPq

buff.ly

What you need to know before taking weight-loss drugs

Weight-loss drugs are not the easy solution that many people believe, especially if you hope to keep the pounds off in the long-term.

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Reposted by Dr Marie Spreckley

IMS Epidemiology, University of Cambridge @imsepidemiology.bsky.social · 09/04/2026

@imsepidemiology.bsky.social’s @drmariespreckley.bsky.social is quoted in a BBC Future’s article, highlighting concerns that a lack of behavioural and lifestyle support for those on weight-loss drugs can lead to further issues. Read the full BBC Future – buff.ly/OTpSvPq

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Dr Marie Spreckley @drmariespreckley.bsky.social · 08/04/2026

Fantastic to see this new study published in JMIR, led by our PhD student Hao Teng. In this qualitative study, we explored how young adults interact with food and nutrition content on social media, and how this can inform the design of effective interventions. www.jmir.org/2026/1/e89344

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Dr Marie Spreckley @drmariespreckley.bsky.social · 02/04/2026

Delighted to contribute to this BBC Future piece out today. Ensuring the right support is in place to optimise outcomes is critical, particularly as use increases. www.bbc.co.uk/future/artic... @bbcstudios.bsky.social @imsepidemiology.bsky.social

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Dr Marie Spreckley @drmariespreckley.bsky.social · 26/03/2026

Wonderful evening presenting on the impact of the cost of living crisis on infant feeding in the first 1,000 days of life. It has been an absolute privilege to work on this important study led by the brilliant @cararuggiero.bsky.social over the past two years. @imsepidemiology.bsky.social

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Reposted by Dr Marie Spreckley

IMS Epidemiology, University of Cambridge @imsepidemiology.bsky.social · 25/03/2026

What are the impacts of food insecurity during the first 1,000 days of life? Join @cararuggiero.bsky.social & @drmariespreckley.bsky.social this Thursday at 6 PM for a free in-person Cambridge Festival talk on insights from the SPROUT study. Register buff.ly/SRMHqfN

Free Cambridge Festival Talk

The cost-of-living crisis and the first 1,000 days of life

With Dr Cara Ruggiero and Dr Marie Spreckley

Thursday 26 March 2026, 6 PM
Old Divinity School, St John's College, Cambridge.

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Dr Marie Spreckley @drmariespreckley.bsky.social · 17/03/2026

GLP-1 therapies work, but how do we balance clinical effectiveness with lived experience, equity, and long-term support? Looking forward to discussing this as a keynote panel member at the Society of Behavioral Medicine Annual Meeting in Chicago on 25 April this year. See you there!

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Dr Marie Spreckley @drmariespreckley.bsky.social · 12/03/2026

Delighted to contribute to this New York Times piece on why weight-loss medications do not work equally well for everyone: www.nytimes.com/2026/03/12/w...

nytimes.com

When Weight-Loss Drugs Don’t Work

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Reposted by Dr Marie Spreckley

IMS Epidemiology, University of Cambridge @imsepidemiology.bsky.social · 04/03/2026

What is the impact of food insecurity during the first 1,000 days of life? Join our free in-person @cambridgefestival.bsky.social talk with @cararuggiero.bsky.social & @drmariespreckley.bsky.social 26 March, 6 PM, Old Divinity School, Cambridge Register buff.ly/HGezP5k

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Reposted by Dr Marie Spreckley

IMS Epidemiology, University of Cambridge @imsepidemiology.bsky.social · 18/02/2026

The researchers are: Dr @cararuggiero.bsky.social - University of Cambridge (@cam.ac.uk) Dr @drmariespreckley.bsky.social - @cam.ac.uk Dr Nikki Davis - @unisouthampton.bsky.social Dr Adrian Brown - University College London (@ucl.ac.uk) Find out more in our blog - buff.ly/LS68rwH

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Reposted by Dr Marie Spreckley

IMS Epidemiology, University of Cambridge @imsepidemiology.bsky.social · 18/02/2026

Researchers from the University of Cambridge, University College London, and the University of Southampton comment on the necessity of keeping nutrition at the heart of management medications for children and adolescents.

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Reposted by Dr Marie Spreckley

IMS Epidemiology, University of Cambridge @imsepidemiology.bsky.social · 18/02/2026

Paediatricians in the UK are prescribing obesity management medications e.g. GLP-1s to children and adolescents for whom lifestyle interventions by themselves are not enough. Find out more in our blog - buff.ly/LS68rwH

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Reposted by Dr Marie Spreckley

IMS Epidemiology, University of Cambridge @imsepidemiology.bsky.social · 17/02/2026

In our free in-person @cambridgefestival.bsky.social talk @cararuggiero.bsky.social & @drmariespreckley.bsky.social will share insights from their research into impacts of food insecurity during the first 1,000 days of life. 26 March, 6 PM, Old Divinity School, Cambridge Register buff.ly/HGezP5k

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Reposted by Dr Marie Spreckley

IMS Epidemiology, University of Cambridge @imsepidemiology.bsky.social · 08/01/2026

Dr Spreckley @drmariespreckley.bsky.social leads the AMPLIFY study that seeks to understand how people experience next-generation weight loss therapies, to help identify the types of information and wrap-around support that are most meaningful and needed in real-world care. buff.ly/835YqxD (4/4)

studies.mrc-epid.cam.ac.uk

AMPLIFY

AMPLIFY explores lived experiences to inform how to support individuals using, or having recently stopped using, incretin-based therapies or weight management.

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Reposted by Dr Marie Spreckley

IMS Epidemiology, University of Cambridge @imsepidemiology.bsky.social · 08/01/2026

Just 12 studies examined nutrition & diet alongside drug treatment, and as trials varied widely in their approaches to dietary advice and nutritional assessment, lacking standardised protocols and reporting, it was difficult to reach robust conclusions to inform the optimal support. (3/4)

Quote from Dr Marie Spreckley of the University of Cambridge "If nutritional care is not integrated alongside treatment, there’s a risk of replacing one set of health problems with another, through preventable nutritional deficiencies and largely avoidable loss of muscle mass. This represents a missed opportunity to support long-term health alongside weight loss."

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Reposted by Dr Marie Spreckley

IMS Epidemiology, University of Cambridge @imsepidemiology.bsky.social · 08/01/2026

In a systematic review published today, Dr Marie Spreckley, Dr Cara Ruggiero, and Dr Adrian Brown found a lack of robust evidence surrounding nutritional advice and support and its impact on calorie intake, body composition, protein adequacy, and patient experiences. buff.ly/Az65PyP (2/4)

Image of Obesity reviews article title "Nutrition strategies for next-generation incretin therapies: a systematic scoping review of the current evidence" bu Marie spreckley, Cara F. Ruggiero and Adrian Brown. Published 07 January 2026.

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Reposted by Dr Marie Spreckley

IMS Epidemiology, University of Cambridge @imsepidemiology.bsky.social · 08/01/2026

New @cam.ac.uk and @ucl.ac.uk research finds people prescribed weight loss drugs such as semaglutide and tirzepatid may not receive sufficient nutritional guidance to support safe and sustainable weight loss, leaving them vulnerable to nutritional deficiencies and muscle loss. 🧵 (1/4)

Image of woman's hands holding semiglutide injection pen over plate of healthy food and cup of tea. Credit: Getty images.

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Dr Marie Spreckley @drmariespreckley.bsky.social · 08/01/2026

We have also launched the AMPLIFY study, which explores people’s lived experiences of using next-generation weight management medications, to help ensure future guidance, support and care pathways are informed by lived experience as well as clinical evidence. studies.mrc-epid.cam.ac.uk/amplify

studies.mrc-epid.cam.ac.uk

AMPLIFY

AMPLIFY explores lived experiences to inform how to support individuals using, or having recently stopped using, incretin-based therapies or weight management.

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Dr Marie Spreckley @drmariespreckley.bsky.social · 08/01/2026

‪We found that nutritional adequacy and nutrition-related support are often not routinely monitored, assessed or reported, even though many studies describe changes in eating patterns and gastrointestinal symptoms that may affect diet quality, lean mass and micronutrient status.‬

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Dr Marie Spreckley @drmariespreckley.bsky.social · 08/01/2026

In this review, we looked across published studies and trials of GLP-1 and GIP/GLP-1 receptor agonist therapies to understand how nutrition is considered alongside their use.

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Dr Marie Spreckley @drmariespreckley.bsky.social · 08/01/2026

In this review, we looked across published studies and trials of GLP-1 and GIP/GLP-1 receptor agonist therapies to understand how nutrition is considered alongside their use.

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Reposted by Dr Marie Spreckley

IMS Epidemiology, University of Cambridge @imsepidemiology.bsky.social · 02/12/2025

Dr Marie Spreckley @cam.ac.uk leads the AMPLIFY study, exploring the lived experiences of people using, or who have recently stopped, incretin-based weight loss therapies, to better understand how to support them with information and wrap-around support. Find out more at buff.ly/AxR0QqR (2/2)

studies.mrc-epid.cam.ac.uk

AMPLIFY

AMPLIFY explores lived experiences to inform how to support individuals using, or having recently stopped using, incretin-based therapies or weight management.

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Reposted by Dr Marie Spreckley

IMS Epidemiology, University of Cambridge @imsepidemiology.bsky.social · 02/12/2025

"A key strength [of the guidance] is the emphasis on combining medication with behavioural support and on the need for equitable access, rather than presenting drugs as a stand-alone solution." @drmariespreckley.bsky.social comments on new WHO guidance on weight loss drugs. buff.ly/BEypph6 (1/2)

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Dr Marie Spreckley @drmariespreckley.bsky.social · 17/11/2025

Delighted to see this out. Thank you! 🙂

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Reposted by Dr Marie Spreckley

IMS Epidemiology, University of Cambridge @imsepidemiology.bsky.social · 17/11/2025

Dr Marie Spreckley is leading the new AMPLIFY study that seeks to understand how people experience next-generation incretin-based therapies, such as semaglutide and tirzepatide, when used for weight management. Read our news post at www.mrc-epid.cam.ac.uk/blog/2025/11... (2/2)

mrc-epid.cam.ac.uk

Exploring lived experiences to help shape future care for next-generation weight management medications - MRC Epidemiology Unit

A new study led by Dr Marie Spreckley is exploring the lived experiences of people using next-generation weight management medications. AMPLIFY (Amplifying Meaningful Perspectives and Lived experience...

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Reposted by Dr Marie Spreckley

IMS Epidemiology, University of Cambridge @imsepidemiology.bsky.social · 17/11/2025

"Nutrition must no longer remain a missing pillar in obesity management medication care." @drmariespreckley.bsky.social @cararuggiero.bsky.social & Adrian Brown on lessons from bariatric interventions on nutritional support needed for GLP-1 receptor agonist assisted weight loss therapy. 🧵(1/2)

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Dr Marie Spreckley @drmariespreckley.bsky.social · 16/11/2025

Fantastic to get to work on this with you! 🙂

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Dr Marie Spreckley @drmariespreckley.bsky.social · 16/11/2025

I am delighted to share our new perspective piece in the International Journal of Obesity: “Bridging the nutrition guidance gap for GLP-1 receptor agonist therapy assisted weight loss: lessons from bariatric surgery.” www.nature.com/articles/s41... @cararuggiero.bsky.social @adrianbrown.bsky.social

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Reposted by Dr Marie Spreckley

IMS Epidemiology, University of Cambridge @imsepidemiology.bsky.social · 12/11/2025

AMPLIFY is a new study led by @drmariespreckley.bsky.social that seeks to understand how people experience next-generation incretin-based therapies, such as semaglutide and tirzepatide, when used for weight management. Read our news post at buff.ly/o6auZ0q 🧵 (1/3)

Image of woman taking part in an online meeting with a diverse group of people.

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Reposted by Dr Marie Spreckley

Cara Ruggiero, PhD, RD, LDN @cararuggiero.bsky.social · 29/09/2025

Congratulations to @drmariespreckley.bsky.social for securing her first independent research grant: Amplifying Meaningful Perspectives and Lived experiences of Incretin therapy use From diverse community voices (AMPLIFY) 🎉Thrilled to be collaborating with you on this!

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Dr Marie Spreckley @drmariespreckley.bsky.social · 29/09/2025

Thanks so much! Can’t wait to get started and see what we discover together 🙂

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