Leonardo Ferreira @drleoferreira.bsky.social · 16/08/2025A new engineered regulatory T cell is born. Chimeric anti-HLA receptor regulatory T cells (CHAR Tregs) inhibit antibody production by B cells from HLA sensitized transplant patients, offering a precise approach to tackle antibody-mediated organ rejection. www.frontiersin.org/journals/imm... 093
Leonardo Ferreira @drleoferreira.bsky.social · 13/05/2025First co-edited special issue completed! Nutrition and Gut Microbiota–Immune System Interplay in Chronic Diseases @Nutrients_MDPI. Six research articles and two reviews. Read our editorial here: www.mdpi.com/2072-6643/17... #immunologymatters 110
Leonardo Ferreira @drleoferreira.bsky.social · 30/04/2025Ten years of Human Islet Research Network (HIRN) & 75 years of NIDDK! Super proud to be part of the HIRN family and this historical perspective & review article. We’re at a turning point in type 1 diabetes understanding & therapy development! #immunologymatters diabetesjournals.org/diabetes/art... 010
Leonardo Ferreira @drleoferreira.bsky.social · 15/04/2025Human stem cell derived heart organoids (almost) invisible to the immune system. Exciting @biorxivpreprint.bsky.social with Dr. Ying Mei @cupress.bsky.social and Dr. Lance Lian @pennstateuniv.bsky.social!!! #immunologymatters #changingwhatspossible www.biorxiv.org/content/10.1... 010
Reposted by Leonardo FerreirabioRxiv Bioengineering @biorxiv-bioeng.bsky.social · 10/04/2025Hypoimmunogenic hPSC-derived cardiac organoids for immune evasion and heart repair www.biorxiv.org/content/10.1101/202… 021
Reposted by Leonardo FerreirabioRxivpreprint @biorxivpreprint.bsky.social · 10/04/2025Hypoimmunogenic hPSC-derived cardiac organoids for immune evasion and heart repair www.biorxiv.org/content/10.1101/202… 021
Leonardo Ferreira @drleoferreira.bsky.social · 02/04/2025The lab’s first @biorxivpreprint.bsky.social of 2025 is out! Jaime Quiroga turned the CAR Treg concept on its head and engineered Tregs that recognize and suppress allo-reactive B cells in HLA sensitized patients! #immunologymatters #changingwhatspossible #CHARTreg www.biorxiv.org/content/10.1... 010
Reposted by Leonardo FerreirabioRxiv Immunology @biorxiv-immuno.bsky.social · 02/04/2025Chimeric anti-HLA antibody receptor engineered human regulatory T cells suppress alloantigen-specific B cells from pre-sensitized transplant recipients www.biorxiv.org/content/10.1101/202… 032
Reposted by Leonardo FerreirabioRxivpreprint @biorxivpreprint.bsky.social · 02/04/2025Chimeric anti-HLA antibody receptor engineered human regulatory T cells suppress alloantigen-specific B cells from pre-sensitized transplant recipients www.biorxiv.org/content/10.1101/202… 011
Leonardo Ferreira @drleoferreira.bsky.social · 27/03/2025We’re presenting at American Association of Immunologists (AAI) 2025! In 2012, my PhD advisor Jack Strominger sponsored my AAI membership. In 2025, I gave my first talk at AAI. In 2022, I sponsored my PhD student Russell Cochrane’s membership. In 2025, he’s been selected for a talk at AAI! #tenyears 030
Leonardo Ferreira @drleoferreira.bsky.social · 21/03/2025Our work on co-engineering stem cells and regulatory T cells to treat type 1 diabetes got a Research Excellence Award by the College of Medicine at the Medical University of South Carolina!!! @leoferreiralab @TheRussLab #immunologymatters #wallofscience www.cell.com/cell-reports... 020
Leonardo Ferreira @drleoferreira.bsky.social · 07/03/2025Outstanding time representing Torpedo Bio as a panelist at SCBio 2025! The future looks bright for innovation and entrepreneurship in South Carolina! #immunologymatters 010
Leonardo Ferreira @drleoferreira.bsky.social · 01/03/2025Starting the month on a great note! Thank you Madalena Pires the Lima for the Great Interview in Descendencias magazine! #immunologymatters #changingwhatspossible descendencias.pt/leonardo-fer... 000
Leonardo Ferreira @drleoferreira.bsky.social · 01/03/2025Expanding the engineered Treg universe! A treat to write this Commentary in Molecular Therapy with Russell Cochrane and Eva Allen on T cell receptor fusion construct (TRuC) Tregs! Congratulations Dimitrios Wagner on the exciting development! www.cell.com/molecular-th... www.cell.com/molecular-th... 000
Leonardo Ferreira @drleoferreira.bsky.social · 19/02/2025How do we make CAR Tregs? Take a peek behind the curtain of the Ferreira Lab at the Medical University of South Carolina and MUSC Hollings Cancer Center! #immunologymatters #changingwhatspossible #CARTregs app.jove.com/v/67200/gene... 000
Leonardo Ferreira @drleoferreira.bsky.social · 19/02/2025Scaling up! Half a billion human T cells gently genetically modified using hydroporation with great yield, cytokine profile, and tumor killing activity in vivo! #immunologymatters #changingwhatspossible www.nature.com/articles/s41... 000
Leonardo Ferreira @drleoferreira.bsky.social · 08/02/2025Outstanding time in Infinita City, Prospera immersing myself in the latest technologies and strategies for maximum life extension! Thank you Max Unfried for the kind invitation. #immunologymatters #changingwhatspossible www.infinita.city/forever-2025... 000
Leonardo Ferreira @drleoferreira.bsky.social · 06/02/2025Thank you RDP Internacional – Radio Portugal (@rtppt) for featuring our work on developing genetically modified stem cells and immune cells to treat type 1 diabetes! #immunologymatters #changingwhatspossible #endT1D rdpinternacional.rtp.pt/estados-unid... www.cell.com/cell-reports... 000
Leonardo Ferreira @drleoferreira.bsky.social · 04/02/2025Changing the course in type 1 diabetes! Energized after co-chairing, speaking, and being a panelist at the 10-Year Anniversary Symposium Organized by The Human Islet Research Network at the NIH! All lectures available online. #immunologymatters videocast.nih.gov/watch=56591 000
Leonardo Ferreira @drleoferreira.bsky.social · 30/01/2025I am the Director of the Immunobiology graduate course at the Medical University of South Carolina! Co-Director Dr. Radhika Gudi and I are excited to take first-year Ph.D. students on this journey through immunoland! #immunologymatters #cgs790 010