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Dr Laura Waters

@drlaurajwaters.bsky.social
2.5K followers 26 following 169 posts

Executive Director Global Medical Affairs Gilead | Honorary HIV doc Royal Free London | Honorary Assoc Professor @UCLGlobalHealth | @peoplefirstcharter@bsky.social founder | ex BHIVA chair | ex NSA HIV @NHSEngland | she/her | Campari | Humanism

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Dr Laura Waters @drlaurajwaters.bsky.social · 02/09/2026
I last accessed this platform in July 2025....!! I deleted my X profile & have mainly used LinkedIn but I'm going to give this another go. As a #gileademployee there's some things I cannot post about....but lots that I can!! So for insights on #HIV #Sexualhealth & #language give me a follow 😘
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Dr Laura Waters @drlaurajwaters.bsky.social · 17/07/2025
Linda Gail Bekker highlighted the critical importance of oral loading with lenacapavir. Missing it significantly delays (to 28 days) the time taken to achieve target concentrations which are reached by day 2 with loading #IAS2025 @iasociety.bsky.social
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Dr Laura Waters @drlaurajwaters.bsky.social · 17/07/2025
Next steps for lenacapavir PrEP #IAS2025 @iasociety.bsky.social
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Reposted by Dr Laura Waters
Myles Helfand @myhelfy.bsky.social · 16/07/2025
In our latest episode of The Future of HIV Care on TheBodyPro, @drlaurajwaters.bsky.social and I share what's on our minds about lenacapavir PrEP approval in the U.S., the growing concern about the future of U.S. HIV clinical guidelines, and... goats. www.thebodypro.com/podcast/hiv/...
thebodypro.com
The Future of PrEP—and HIV Guidelines Under Threat
A discussion about what comes next following the U.S. approval of lenacapavir PrEP, and about growing concerns for the future of HIV clinical guidelines within the U.S.
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Dr Laura Waters @drlaurajwaters.bsky.social · 16/07/2025
Impact of PEPFAR cuts on HIV care in Mozambique #IAS2025 with 3rd highest no of PWH & 2nd highest new diagnoses, 67% of funding from PEPFAR in 2022. - 14% reduction in ART initiations - 39% increase in ART interruption - reduced VL testing & viral suppression, esp children @iasociety.bsky.social
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Dr Laura Waters @drlaurajwaters.bsky.social · 16/07/2025
#IAS2025 first ever lenacapavir PrEP implementation study will be in Brazil! Will include a mobile PrEP unit in Sao Paolo to best reach communities who will benefit @iasociety.bsky.social
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Dr Laura Waters @drlaurajwaters.bsky.social · 16/07/2025
At the IAS members meeting with a wondrous panel (see pic). I'm finding the discussions about funding & the struggles people experience trying to fund their attendance really emotive. This will be increasingly challenging in the future & I wish I had a solution #ias2025
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Dr Laura Waters @drlaurajwaters.bsky.social · 15/07/2025
The much anticipated DO-IT trial shows no impact of switch from TAF + INSTI to DOR (with TAF or TDF) on weight in people with obesity. Considering switching ART only to address weight change? DON'T DO-IT..... #IAS2025 @iasociety.bsky.social
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Dr Laura Waters @drlaurajwaters.bsky.social · 15/07/2025
The TECAIN Study (tricholoacetic acid vs electrocautery for AIN treatment in people with HIV) at 24W showed TCA non-inferior to ECA. #IAS2027 @iasociety.bsky.social @tristanjbarber.bsky.social
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Dr Laura Waters @drlaurajwaters.bsky.social · 15/07/2025
IMPALA results at #IAS2025 1 incident HBV infection in the CAB/RPV arm No evidence of HBV reactivation (note people with detectable cAb but sAb <10 were excluded) @iasociety.bsky.social @profchloeorkin.bsky.social @tristanjbarber.bsky.social
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Dr Laura Waters @drlaurajwaters.bsky.social · 14/07/2025
Rosemary Mburu #ias2025 "Science is not just data! It is DIGNITY. Investment in people is not just nice to have, it's creating powerful agents for change. RESILIENCE MUST BE MET WITH RESPECT @iasociety.bsky.social
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Dr Laura Waters @drlaurajwaters.bsky.social · 14/07/2025
Beatriz Grinszetjn Opens #ias2025! While she can't provide a recipe for success in current climate, there are key factors 1. EVIDENCE 2. SOLIDARITY 3. TRUTH Let us make the most of our time together at the conference to "reaffirm, refocus & rebuild!" @iasociety.bsky.social
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Dr Laura Waters @drlaurajwaters.bsky.social · 14/07/2025
New @who.int postnatal prophylaxis guidelines : Infants at ow-risk - preferred: 6W NVP for 6W - alternative: DTG or 3TC for 6W Infants at high-risk - ABC + 3TC + DTG for 6W - plus extended PNP during breastfeeding (nevirapine preferred, DTG or 3TC alternatives) #IAS2025 @iasociety.bsky.social
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Dr Laura Waters @drlaurajwaters.bsky.social · 14/07/2025
New World Health Organization guidelines recommend darunavir as preferred PI and new appearance for LA-CAB/RPV as a switch option for people who are virally suppressed. #IAS2027 @iasociety.bsky.social @who.int @tristanjbarber.bsky.social
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Dr Laura Waters @drlaurajwaters.bsky.social · 14/07/2025
@who.int guidelines launch at #IAS2025 includes the just released guidelines on LEN PrEP including recommendation to use HIV rapid tests, NAAT too slow & expensive.... iris.who.int/bitstream/ha... @tristanjbarber.bsky.social
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Dr Laura Waters @drlaurajwaters.bsky.social · 14/07/2025
Mitchell Warren of AVAC shares data, based on many assumptions, of potential injectable PrEP use in 2026 based on 2024 oral uptake & preference data. And the ways forward.....prioritise, prioritise, prioritise (sorry, I changed the spelling 😘) #IAS2025
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Dr Laura Waters @drlaurajwaters.bsky.social · 12/07/2025
We are at an absolutely critical point in the HIV response which is why the @iasociety.bsky.social conference in Kigali so so very important. And when LISTENING is more important than ever, the live translation feature for the main sessions is particularly welcome....well done IAS #IAS2025
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British Association for Sexual Health and HIV (BASHH) @bashhuk.bsky.social · 09/06/2025
📢 BASHH has today published national clinical guidelines on the use of doxyPEP. This makes the UK one of the first countries globally to offer formal clinical direction on this STI prevention strategy. 🔗 Read our full statement & access the guidelines: bit.ly/4475DDK
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Dr Laura Waters @drlaurajwaters.bsky.social · 10/06/2025
Outstanding presentation on gender affirming care for adults in the UK from Alison Berner #bashh2025 The 2 screenshots provide invaluable advice, & until new NHSE guidance is produced, the 2019 advice applies @bashhuk.bsky.social
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Myles Helfand @myhelfy.bsky.social · 10/04/2025
What happens when you throw @paulsaxmd.bsky.social, @drlaurajwaters.bsky.social, Monica Gandhi, and David Wohl into a (virtual) room together and ask them to talk about anal cancer screening guidelines in HIV care? Weird question to ask, but I've got the answer. www.thebodypro.com/video/hiv/an...
thebodypro.com
Have Anal Cancer Screening Guidelines Gone Too Far?
A panel of expert HIV clinician-researchers discusses the practical challenges of implementing current anal cancer screening guidelines, as well as alternative approaches to identify those at highest ...
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Fast Track Cities LDN @londonftci.bsky.social · 15/04/2025
Fast-Track Cities is a partnership working towards zero new #HIV infections, zero deaths and zero stigma before 2030. For #TeamTuesday meet Dr Laura Waters, HIV National Specialty Advisor and member of our leadership team fasttrackcities.london/team/laura-w… @drlaurajwaters.bsky.social
fasttrackcities.london
Dr Laura Waters - Fast-Track Cities London
Laura Waters is an HIV & Sexual Health consultant at The Mortimer Market Centre, London. She is the National Specialty Advisor for HIV, chairing the group that advises NHS England on HIV treatment and the immediate past chair of the...
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Doctor Steve Taylor @docstevetaylor.bsky.social · 18/04/2025
Volunteers wanted! , Are you a sexually active woman who might benefit from #PrEP ? @profygilleece.bsky.social @profchloeorkin.bsky.social @drlaurajwaters.bsky.social @drrageshri.bsky.social @savinglives.bsky.social www.bbc.co.uk/news/article...
bbc.co.uk
Women offered jabs in HIV prevention trial
Project leaders are looking for participants in Birmingham, Manchester, London and Brighton.
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Saving Lives UK @savinglives.bsky.social · 23/04/2025
The Birmingham AIDS & HIV Memorial Legacy Project 'Cover Up Quilts' are on display at #BHIVA25. Come & meet the Project Lead, Garry Jones and see several quilts made by people living with #HIV. This project was part funded by the @bhiva.bsky.social @drlaurajwaters.bsky.social community fund.
Four quilts, approximately 1 metre wide by 2 metres tall, on display in a wooden room. The one closest to the camera reads "Be positive. Being Positive, No Shame". Another has the U=U slogan on a Union Jack, with a pride flag below.
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Dr Laura Waters @drlaurajwaters.bsky.social · 18/03/2025
Huge congratulations to my dearest friend & colleague @tristanjbarber.bsky.social who will be the new @bhiva.bsky.social chair from November!!!! Wise & stylish shoes to fill but I'm sure @profygilleece.bsky.social is delighted it's your feet next 😘😘😘😘
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Paul Sax @paulsaxmd.bsky.social · 17/03/2025
Totally thrilled to be working with @drlaurajwaters.bsky.social and Dr. Magnus Gisslen again to summarize the top studies from #CROI2025. #IDSky #HIVSky Please sign up to join us! 31 March, 2025 medevents.se/events/ch2-2025
Description of planned progeam.
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Jillian Lau @jillianlau.bsky.social · 12/03/2025
One observation from me during the hot new #HIV therapies session at #CROI2025. Others have been posting abt the data showing options for LA CAB/bNAb, ISL/DOR, and CAB/RPV in Africa but my hot take is: Look at the impressive % of women in these trials! 58% in CARES 21 & 40% in the ISL/DOR studies
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Narad Trabant @borisogon.bsky.social · 13/03/2025
The Gilead press release (scroll down to "landmark"): www.gilead.com/news/news-de...
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Dr Laura Waters @drlaurajwaters.bsky.social · 13/03/2025
@brendacrabtreer.bsky.social makes excellent point in excellent closing session on INSTI resistance. We should talk about 'INSTI resistance' not 'DTG resistance'. Some LMIC have bictegravir too you know....! And much INSTI resistance is due to prior exposure to 1st generation INSTI too.... #CROI2025
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Tristan J Barber @tristanjbarber.bsky.social · 12/03/2025
💯 this. We need to *lead* people! #CROI2025
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Dr Laura Waters @drlaurajwaters.bsky.social · 12/03/2025
FFFS. Maybe I'm just particularly grumpy & tired today but stop saying that PEOPLE FAILED. Their treatment failed. Especially when they are on injectables and had all their injections on time. I'm literally flinching each time I hear it. @peoplefirstcharter.bsky.social #CROI2025
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Dr Laura Waters @drlaurajwaters.bsky.social · 12/03/2025
Sobering talk from an excellent Jeremy Nel on global implications of INSTI resistance. "Nuisance for HIC but profound challenges for LMIC" - so true #CROI2025
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Dr Laura Waters @drlaurajwaters.bsky.social · 12/03/2025
It doesn't take much to make language person-first..... "those failing ART" - is it the person's fault?! "those on failing ART" - 'blames' the regimen not the person Small things, big impact #languagematters #CROI2025 www.peoplefirstcharter.org @peoplefirstcharter.bsky.social
peoplefirstcharter.org
People First Charter
Person first language
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Dr Laura Waters @drlaurajwaters.bsky.social · 12/03/2025
Sorry ViiV but if you believe Q2M CAB as good as QM, why, when combining CAB with the bNAb N6LS, is it more cautious to use QM? We know there are numerically more VF on Q2M CAB/RPV than QM & this study design suggests you have more faith in that QM dose. Unless I missed something? #CROI2025
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Dr Laura Waters @drlaurajwaters.bsky.social · 12/03/2025
More daily DOR/ISL from @profchloeorkin.bsky.social #CROI2025 This time open-label, various ART - efficacy (incl 5 with viraemia on DOR/ISL) in pic. Weight gain on DOR/ISL driven by removal of weight suppressive TDF and/or EFV
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Dr Laura Waters @drlaurajwaters.bsky.social · 12/03/2025
More daily DOR/ISL from @profchloeorkin.bsky.social #CROI2025 This time open-label, various ART - efficacy (incl 5 with viraemia on DOR/ISL) in pic. Weight gain on DOR/ISL driven by removal of weight suppressive TDF and/or EFV
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Dr Laura Waters @drlaurajwaters.bsky.social · 12/03/2025
#CROI2025 continued Biktarvy vs switch to daily ISL/DOR with ISL at safer lower dose of 0.25mg. ISL/DOR non-inferior at W48, 2 CVFs, no RAMs, both resuppressed in Biktarvy, no diff in CD4/TLC. 2 cases acute HBV in cAb- & sAb- people
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Dr Laura Waters @drlaurajwaters.bsky.social · 12/03/2025
Ph2b EMBRACE #CROI2025 Q4M N6LS + QM CAB bNAb SC vs IM vs continued oral in VS ppl. 4CVFs on N6LS/CAB, 1 with CAB RAMs, 3 with N6LS resistance. IV will be going forwards
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Dr Laura Waters @drlaurajwaters.bsky.social · 12/03/2025
96W CARES CAB/RPV. Efficacy remains high and non-inferior vs continued oral ART (97% <50) 4 VFs on LA (0 on PO) 3/4 with dual class RAMs (1 with baseline RPV RMAs) 1/4 not sequenced. Great results.
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Dr Laura Waters @drlaurajwaters.bsky.social · 12/03/2025
ACTG5418: Tecovirimat vs PBO clade 2 mpox n=344 #CROI2025 Study stopped early due to DSMB futility analysis (unbeknownst to study team?!) 25% recruited remotely HR for clinical resolution....0.98 (o.74-1.31) & no diff in subgroup analysis incl symptom duration. No difference in viral clearance/pain
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Dr Laura Waters @drlaurajwaters.bsky.social · 12/03/2025
#CROI2025 19-43% C19 household transmission rates. SCORPIO randomised >2300 contacts to ensitrelvir vs PBO (78% enrolled within 48h of symptom onset in index case, 37% of whom were at high risk of complications. 67% reduction in C19 acquisition 1 at day 10!! 76% if high risk! WOW.
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Dr Laura Waters @drlaurajwaters.bsky.social · 12/03/2025
Letermovir (CMV terminase inhibitor) does some good stugg. Delightfully passionate conclusion!! #CROI2025
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Dr Laura Waters @drlaurajwaters.bsky.social · 12/03/2025
What is it with the facile images representing mortality at #CROI2025?! After the grim reaper earlier today, now we have a gravestone. Do we really need these pictures, especially when they are so starkly associated with the early years of the HIV epidemic. REALLY?!?!?
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Dr Laura Waters @drlaurajwaters.bsky.social · 12/03/2025
#CROI2025 semaglutide stablises biological ageing in people with HIV.
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Dr Laura Waters @drlaurajwaters.bsky.social · 12/03/2025
Can epigenetic clocks predict clinical events? Some so, some don't. GrimAge did best - but what a name! You can do your own for just $325....?! myagingtests.com/product/epig... #CROI2025
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Dr Laura Waters @drlaurajwaters.bsky.social · 12/03/2025
More from REPRIEVE #CROI2025. Frailty prognostic for MACE HR 1.76/2.14 for pre-frail/frail vs non-frail) No impact of frailty on pitavastain effect though event number & sample size in group with frailty small.
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Dr Laura Waters @drlaurajwaters.bsky.social · 12/03/2025
Link to paper Steve Grinspoon mentioned at #CROI2025. Conclusion: PCE risk score underpredicted cardiovascular events in women & Black or African American men in high-income countries and overpredicted cardiovascular events in low-income and &-income countries. www.thelancet.com/journals/lan...
thelancet.com
Performance of the pooled cohort equations and D:A:D risk scores among individuals with HIV in a global cardiovascular disease prevention trial: a cohort study leveraging data from REPRIEVE
Among the global cohort of people with HIV in REPRIEVE, the PCE risk score underpredicted cardiovascular events in women and Black or African American men in high-income countries and overpredicted ca...
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Dr Laura Waters @drlaurajwaters.bsky.social · 12/03/2025
REPRIEVE #CROI2025 - relating entry risk factors to MACE. Some trad (age/ASCVD risk) + non-trad risk factors (hsCRP/IL-6/non-calcified plaque) more common in ppl with MACE. LDL slightly LOWER?! Non-calcified plaque predictive of MACE (8% vs 3% in ppl without plaque).Lower CRP on statin.
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Dr Laura Waters @drlaurajwaters.bsky.social · 12/03/2025
Scant data on CAD in ppl with HIV in Africa. Lower rates of coronary artery disease in Uganda than other cohorts & smaller difference between people with/without HIV #CROI2025 We can't extrapolate US data to other regions - study the populations affected to inform public health interventions
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Dr Laura Waters @drlaurajwaters.bsky.social · 12/03/2025
Remember START?! #CROI2025 CVD with extended FU, rates pre/post unblinding. No difference between groups randomised to immediate vs deferred ART. Caveats: young age, low event rate
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Dr Laura Waters @drlaurajwaters.bsky.social · 12/03/2025
Really?! Maybe it's just me? #CROI2025
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