iiinova — where your digital self keeps evolving

John Barbieri, MD, MBA @drjohnbarbieri.bsky.social · 26/02/2025

Lately, we've seen a lot of discussion about the potential risk of benzoyl peroxide products breaking down into benzene. In this letter, we discuss some of the limitations with respect to the methodology and framing of the recent Kucera et al. article in the JID: www.jidonline.org/article/S002...

jidonline.org

The need for transparency and careful messaging regarding the potential for benzoyl peroxide products to form benzene

We read with interest the article by Kucera et al. (Kucera et al. 2024) and agree that this topic is of tremendous importance given the ubiquitous use of benzoyl peroxide (BPO) for acne and other skin...

020

John Barbieri, MD, MBA @drjohnbarbieri.bsky.social · 19/02/2025

Minocycline-MR 40mg was recently FDA approved for rosacea. In this video, I will review the clinical trial data and share my thoughts on where it fits among our existing treatment options: #rosacea #minocycline #emrosi youtu.be/103ncqVznGk

How good is the new Minocycline-MR (Emrosi) for rosacea | Dermatologist explains

John Barbieri, MD, MBA @drjohnbarbieri.bsky.social · 12/02/2025

Excited to share work with @labmuffin.com, Courtney Rubin, and James Pham, identifying how formulation characteristics might be associated with benzene levels in benzoyl peroxide products. Some helpful hypotheses to guide future product development. jamanetwork.com/journals/jam...

jamanetwork.com

The Role of Formulation in Benzene Formation in Benzoyl Peroxide Products

This quality improvement study examines the effects of formulation on benzene levels detected in over-the-counter benzoyl peroxide products.

141

John Barbieri, MD, MBA @drjohnbarbieri.bsky.social · 06/02/2025

In this latest video, I review common reasons why isotretinoin is not working and how to address these clinical scenarios: youtu.be/gEc2qxdEH6Q

Why Accutane (isotretinoin) isn’t working | Dermatologist and acne expert explains

John Barbieri, MD, MBA @drjohnbarbieri.bsky.social · 27/01/2025

We often consider GoodRx to reduce out-of-pocket costs. In this @JAADjournals study, we find that @costplusdrugs frequently has lower prices for derm drugs (and the mail order aspect may be more convenient). Another good option to help with affordability. pubmed.ncbi.nlm.nih.gov/39863169/

pubmed.ncbi.nlm.nih.gov

Comparing Prescription Drug Saving Platforms for Dermatology: A Cost Analysis of Mark Cuban Cost Plus Drugs, GoodRx, and Amazon RxPass - PubMed

Comparing Prescription Drug Saving Platforms for Dermatology: A Cost Analysis of Mark Cuban Cost Plus Drugs, GoodRx, and Amazon RxPass

040

John Barbieri, MD, MBA @drjohnbarbieri.bsky.social · 22/01/2025

Just out in @JAMADerm, we describe the psychometric properties of the 1-item ACORN Patient Global Assessment, which correlates well with the CASS IGA and also is highly responsive to change. This can be particularly useful for online surveys/assessments. jamanetwork.com/journals/jam...

jamanetwork.com

Validation of the ACORN Patient Global Assessment

This survey study evaluates the measurement properties for acne severity of the Acne Core Outcome Research Network (ACORN) patient global assessment.

000

John Barbieri, MD, MBA @drjohnbarbieri.bsky.social · 22/01/2025

Should we start with spironolactone or doxycycline for women with acne? Check out my breakdown of the FASCE trial here: youtu.be/zRbPfSCn9Ow

Spironolactone or oral antibiotics? Which is best? | FASCE Trial | Dermatologist explains

John Barbieri, MD, MBA @drjohnbarbieri.bsky.social · 10/01/2025

Do we really need to check frequent labs for isotretinoin? In this video, I go through the evidence about why we likely aren't getting much value from our current approach and even make a case for no monitoring: youtu.be/UpsW1iN9FRw

Does Accutane (isotretinoin) require lab monitoring? | Dermatologist and acne expert explains

Tasha Tolliver @tashat.bsky.social · 23/12/2024

021

Reposted by John Barbieri, MD, MBA

Some of the best evidenced-based info on acne treatment right here! @drjohnbarbieri.bsky.social #DRESSsyndrome #acnetreatment

011

John Barbieri, MD, MBA @drjohnbarbieri.bsky.social · 22/12/2024

Want to learn more about which are the best oral antibiotics for the treatment of acne, including the relative role of doxycycline, minocycline, sarecycline (Seysara), trimethoprim-sulfamethoxazole (Bactrim), amoxicillin, and azithromycin, among others? Check out this video: youtu.be/RgMXi92UjnQ

What are the best antibiotics for acne | Dermatologist and acne expert explains

John Barbieri, MD, MBA @drjohnbarbieri.bsky.social · 19/12/2024

020

Catch up on some of the biggest topics, studies, and new medications for acne in my latest year-in-review video: youtu.be/vxqxzDYGSsg

Catch up on the biggest acne developments of 2024: Year in Review | Dermatologist Explains

John Barbieri, MD, MBA @drjohnbarbieri.bsky.social · 09/12/2024

121

In JAAD, we find evidence that acne may be a risk factor for fractures. This aligns with evidence that acne is associated with low vitamin D levels or might be related to pleiotropy or systemic inflammation www.sciencedirect.com/science/arti...

jaad.org

DEFINE_ME

110

John Barbieri, MD, MBA @drjohnbarbieri.bsky.social · 02/12/2024

Isotretinoin can be highly effective for #acne and is the only prescription treatment that can provide a lasting remission. While we often discuss skin dryness, we don’t often consider the eyes. In this thread, let's explore the effects of #isotretinoin on the eye. #dermsky 1/9

182

John Barbieri, MD, MBA @drjohnbarbieri.bsky.social · 02/12/2024

Pityrosporum folliculitis ("fungal acne") can be easy to miss and needs different treatments than run of the mill acne. In this video, I go over what to look for and how to treat this condition: www.youtube.com/watch?v=n0YH...

youtube.com

Are those pimple breakouts fungal acne? Dermatologist explains Pityrosporum folliculitis

Dr Michelle Wong - Lab Muffin Beauty Science @labmuffin.com · 29/11/2024

Reposted by John Barbieri, MD, MBA

Real world data shows no correlation between benzoyl peroxide use and benzene blood levels, or leukaemia/lymphoma/internal malignancies 👇🏻

0271

John Barbieri, MD, MBA @drjohnbarbieri.bsky.social · 17/11/2024

While isotretinoin can be a great acne treatment for the right person, side effects can often be a challenge. In this video, I discuss how to avoid prevent some of the main side effects of isotretinoin such as dryness: youtu.be/KU3NsjdA50o

How to avoid side effects from Accutane (isotretinoin) – Dermatologist and acne expert explains