David Griffin 🦠🧫💉 @drdavidwjg.bsky.social · 17/01/20263/ The study highlights a need to improve awareness and address misconceptions about organ transplantation for PWH, suggesting potential for better education and policy changes. 000
David Griffin 🦠🧫💉 @drdavidwjg.bsky.social · 17/01/20262/ #PWH were less likely to believe they could receive or donate organs compared to #PWoH. Despite this, PWH showed a higher willingness to be deceased donors. Concerns varied, with PWH worried about HIV superinfection and PWoH concerned about HIV acquisition from organ transplants. 100
David Griffin 🦠🧫💉 @drdavidwjg.bsky.social · 17/01/20261/ 🚨Recent #PhD publication🚨 Knowledge and Attitudes about Solid Organ #Transplantation for People with HIV in Australia: A Cross-sectional Survey of People with and without #HIV #SOT #TxID #IDSky #TxIDSky #healthequity journals.lww.com/jaids/abstra...journals.lww.com 120
David Griffin 🦠🧫💉 @drdavidwjg.bsky.social · 16/01/2026Our recent correspondence in #lancet: “We must improve awareness among people with #HIV and health-care providers of their eligibility to receive and donate organs…we must ensure that equity is a non-negotiable standard.” www.thelancet.com/journals/lan...thelancet.comA call for equity in organ transplantation for people with HIVThe Lancet Series on solid organ transplantation is a timely call to advance global equity and highlights the importance of ensuring those who might benefit from solid organ transplantation have fair ... 000
David Griffin 🦠🧫💉 @drdavidwjg.bsky.social · 16/12/2025🚨New Publication🚨 Great to see this #PhD publication out. Knowledge and attitudes about #SOT for people with #HIV among Australian healthcare providers: a cross‐sectional survey onlinelibrary.wiley.com/doi/10.1111/... Thanks to the participants and collaborators for #IDSky #HIVsky #TxIDSkyonlinelibrary.wiley.comKnowledge and attitudes about solid organ transplantation for people with human immunodeficiency virus among Australian healthcare providers: a cross‐sectional surveyBackground People with human immunodeficiency virus (HIV) (PWH) are experiencing a normalisation in life expectancy, but with an increasing burden of chronic comorbidities and end-stage organ diseas..... 010
David Griffin 🦠🧫💉 @drdavidwjg.bsky.social · 15/09/20252/ #HIV has minimal influence on organ allocation in respondents, but is a significant barrier to the selection of a potential donor, even an appropriate recipient. Organ quality was the most influential factor in selection of a prospective donor. 000
David Griffin 🦠🧫💉 @drdavidwjg.bsky.social · 15/09/2025Pleased to share results of our discrete choice experiment of the influence of HIV on organ procurement and allocation in Australia #HIVAIDS2025 #healthequity #IDsky #HIVsky #TxIDsky #PhD 161
David Griffin 🦠🧫💉 @drdavidwjg.bsky.social · 15/08/2025🚨Review just out in @hivmedicine.bsky.social 🚨 “Solid organ transplantation in people with #HIV: Outcomes, obstacles and opportunities” #IDSky #HIVSky #TxIDSky ft. David Ruschena, Prof. James McMahon, Prof. Jenny Hoy doi.org/10.1111/hiv....doi.orgSolid organ transplantation in people with HIV: Outcomes, obstacles and opportunitiesObjective People with HIV experience disparate access to solid organ transplantation (SOT), despite mounting evidence for comparable outcomes. This review aims to understand the outcomes following S... 080
David Griffin 🦠🧫💉 @drdavidwjg.bsky.social · 12/03/2025Important #latebreaker study at #CROI2025 SCORPIO-PEP phase III RCT showed ensitrelvir (Day 1: 375mg, Day 2-5: 125mg) reduced PCR positive, symptomatic #COVID19 in HHC if started w/in 72 hrs of index case symptomatic C19 by 67%. Including in those with high risk progression. Need ICH and RACF data! 020
David Griffin 🦠🧫💉 @drdavidwjg.bsky.social · 11/03/2025#CROI2025 Published today: #Pharmacokinetics and safety of once-yearly lenacapavir: a phase 1, open-label study www.thelancet.com/journals/lan... Great to see truly “long acting” therapies for HIV and PrEP emerging. the bar for #HIV #vaccines is ever higher!thelancet.comPharmacokinetics and safety of once-yearly lenacapavir: a phase 1, open-label studyFollowing administration of once-yearly intramuscular lenacapavir, median plasma concentrations exceeded those associated with efficacy in phase 3 studies of twice-yearly subcutaneous lenacapavir for ... 0132
Reposted by David Griffin 🦠🧫💉Juan Michael Porter II @juanmichaelii.bsky.social · 10/12/2024Calling Our Patients “High Risk” Hurts Them "Being called risky or associated w risk b/c of your sexual health decisions makes most people feel ashamed. And that shame is nothing more than another barrier to care. " A banger op-ed by @jncherabiemd.bsky.social www.thebodypro.com/hiv/calling-...thebodypro.com 392
Reposted by David Griffin 🦠🧫💉JAMA @jama.com · 28/11/2024Cervical cancer mortality in US women younger than 25 years significantly declined between 2016 and 2021, likely due to the widespread adoption of HPV vaccination. ja.ma/4i9ghPC 322052612
David Griffin 🦠🧫💉 @drdavidwjg.bsky.social · 24/11/2024100% There was some really interesting data presented at #CROI2024 which explored racial disparities in the lifetime risk of acquiring HIV and highlighted some of those issues of intersectionality. www.aidsmap.com/news/mar-202... #HIVsky #IDskyaidsmap.comProgress in reducing new HIV diagnoses much slower for Black men in the USLifetime risk of acquiring HIV has decreased for Black gay and bisexual men in the US, from 1 in 2 from 2010 to 2014 to 1 in 3 from 2017 to 2021, according to data presented to the Conference on Retro... 110
David Griffin 🦠🧫💉 @drdavidwjg.bsky.social · 23/11/2024Ten Americas: a systematic analysis of life expectancy disparities in the USA - @thelancet.bsky.social Somber update on the 8 Americas study; highlights growing inequities in life expectancy, impact of structural racism and disproportionate impact of #COVID19 www.thelancet.com/journals/lan... 174
David Griffin 🦠🧫💉 @drdavidwjg.bsky.social · 23/11/2024Dr Eloise Williams gave an important update confirmatory testing for #HIV in Australia. #MicroSky #HIVsky #IDsky #HIVinFocus - Use of accredited NAAT in diagnostics (cf monitoring) on separate sample to initial serology - p24 Ag immunoassay (no longer available) - (traditional) western blot 001
David Griffin 🦠🧫💉 @drdavidwjg.bsky.social · 23/11/2024Vikas Parwani from HIV/AIDS Legal Center shares a brief insight into immigration to Aus for #PWH. Immigration exempt from discrimination laws that protect #PWH. #HIV can be barrier due to perceived cost, but opportunities for ‘health waiver’ exist. HIV not the only barrier #PWH face. #HIVinFocus 000
David Griffin 🦠🧫💉 @drdavidwjg.bsky.social · 23/11/2024None, though I don’t have many people on injectables at this stage. I think more will be inclined to switch, once LAI are Q6M, or can be self administered. (LEN + ? 👀) Frequent clinical attendance and frequent injections seem major deterrents. Cab-LA not yet funded as PrEP here either. 010
David Griffin 🦠🧫💉 @drdavidwjg.bsky.social · 23/11/2024A/Prof. Mina John from Royal Perth Hospital, presents Western Australian data on implementation LAI ART in hard to reach populations, mirroring #UCSF data; improved retention in care and virological suppression. Multiple other benefits. #HIVsky #IDsky 120
David Griffin 🦠🧫💉 @drdavidwjg.bsky.social · 23/11/2024👍🏼 Same! (Plus Simva-, and Pravastatin, thou not sure why anyone would use these preferentially…) We have: Rosuvastatin 5-40mg Atorvastatin 10-80mg I typically start with rosuvastatin 10mg, unless pt on boosted PI (then typically half) 010
David Griffin 🦠🧫💉 @drdavidwjg.bsky.social · 23/11/2024Interesting! We use www.cvdcheck.org.au/calculator which is based on the NZ PREDICT-1° equation. I mostly use it in conversations about risk and impact of risk factor modification (eg smoking cessation). None of our calculators incorporate HIV, ART, etc, and likely underestimate risk.cvdcheck.org.auAustralian cardiovascular disease risk calculator | AusCVDRisk 010
David Griffin 🦠🧫💉 @drdavidwjg.bsky.social · 22/11/20243/ #HIVinFocus International guidelines recommend implementing the #Reprievestudy findings with different thresholds of #CVD risk statin therapy. Australian guidance most closely aligns with the EACS recommendation. 100
David Griffin 🦠🧫💉 @drdavidwjg.bsky.social · 22/11/20242/ Australian CVD risk calculators typically assign a lower risk to #PWH than AHA/ACC score. International guidelines recommend implementing this evidence differently. 100
David Griffin 🦠🧫💉 @drdavidwjg.bsky.social · 22/11/2024A/Prof Janine Trevillyan from #AustinHealth describes the challenges of applying the #REPRIEVEstudy in Australia; we don’t have pitavastatin and use different risk calculators. #IDsky #HIVsky Atorva- and rosuvastatin reduce surrogates of CVD risk, though choosing ideal biomarker can be challenging. 110
David Griffin 🦠🧫💉 @drdavidwjg.bsky.social · 22/11/20246/ #REPRIEVEstudy also highlighted that #CVD risk calculators tend to overestimate CVD risk in developing countries, but underestimate risk in women. 000
David Griffin 🦠🧫💉 @drdavidwjg.bsky.social · 22/11/20245/ #REPRIEVEstudy showed that statins were safe (pitavastatin was chosen because it doesn’t interact with PIs), with a non-sig trend towards incident #diabetes, though glycaemic control was curiously unchanged. 100
David Griffin 🦠🧫💉 @drdavidwjg.bsky.social · 22/11/20244/ #REPRIEVEstudy demonstrated definitively that statins reduce CVD risk in people with #HIV 35% with low to moderate #ASCVD risk at baseline. 100
David Griffin 🦠🧫💉 @drdavidwjg.bsky.social · 22/11/20243/ mechanistically statins reduce CVD risk through several mechanisms; LDL lowering, plaque stabilization, dampening inflammation. Interestingly #REPRIEVEstudy proteomic analysis suggested PCOLCE may be important in pitavastatin impact on collagen deposition. 100
David Griffin 🦠🧫💉 @drdavidwjg.bsky.social · 22/11/20242/ importance of identifying and addressing lifestyle factors, social and psychological determinants of health to reduce #CVD risk 100
David Griffin 🦠🧫💉 @drdavidwjg.bsky.social · 22/11/2024Day 2 #HIVinFocus Prof. Currier from #UCLA offering insights into CVD risk in #PWH. First, association between clonal hematopoiesis and #CVD risk in #HIV demonstrated in several cohorts. 100
David Griffin 🦠🧫💉 @drdavidwjg.bsky.social · 22/11/2024#HIVsky #IDsky Remember cystatin C as an alternative to creatinine for estimating renal function in people with HIV with elevated creatinine on INSTI and/or cobicistat. - nephrologist, Dr Nichita GAVRILESCU #HIVinFocus 0144
David Griffin 🦠🧫💉 @drdavidwjg.bsky.social · 22/11/2024Great talk by Endocrinologist A/Prof. Priya Sumithran at #HIVinFocus symposium. - weight loss is an uphill battle - pharmacological management available with additional health benefits - questions remain about functional impact of muscle loss - meds only work while taking them! #IDsky #HIVsky 010
David Griffin 🦠🧫💉 @drdavidwjg.bsky.social · 22/11/2024Prof. Jenny Hoy, summarises ART and weight gain at #HIVinFocus symposium at Alfred Health. #HIVSky 050
David Griffin 🦠🧫💉 @drdavidwjg.bsky.social · 20/11/2024As a Melburnian, I had no idea VIDRL performed this assay. Not surprised though, they seem to have PCRs for everything! 000
Reposted by David Griffin 🦠🧫💉Todd Gleeson, MD, MPH @toddgleeson.bsky.social · 20/11/2024Lower-cost versions of the #HIV prevention drug lenacapavir to be made available in 120 low- & middle-income countries. #IDSky #GlobalHealth #PublicHealth #PrEP www.theguardian.com/global-devel...theguardian.com‘Gamechanger’ HIV prevention drug to be made available cheaply in 120 countriesGilead Sciences announces deal to manufacture generic versions of lenacapavir, but critics say it excludes many countries where incidence is highest 292
David Griffin 🦠🧫💉 @drdavidwjg.bsky.social · 18/11/2024One can try to slice the data however they will, but the ⬇️ in morbidity, mortality and incidence of several infectious diseases due to #vaccination is irrefutable. We’ve seen time and again, the consequences of disruption of immunisation programs (e.g. MMR in Samoa), and ⬇️ in herd immunity #IDsky 0110
Reposted by David Griffin 🦠🧫💉Allen Cheng @peripatetical.bsky.social · 16/11/2024Allen Yung's Golden Rules of ID. Copied over from the Other Place for @kottonnelson.bsky.social #IDSky 43511
David Griffin 🦠🧫💉 @drdavidwjg.bsky.social · 17/11/2024Similar to @paulsaxmd.bsky.social, I recall a pt with documented negative serology 18 months prior to first ADI. Rapidity of progression is associated with virologic set point, the immune response to HIV, and a list of host and viral factors. 110
David Griffin 🦠🧫💉 @drdavidwjg.bsky.social · 16/11/2024Agreed. With #CMV, do we think the risk of #IFI is a direct effect of the virus (eg through IL-10 homolog, etc), a reflection of the net state of immunosuppression, or both? #IDsky #TxIDSkymedia.tenor.coma little girl is asking why not both while standing in a kitchen .ALT: a little girl is asking why not both while standing in a kitchen . 210
David Griffin 🦠🧫💉 @drdavidwjg.bsky.social · 16/11/2024Great point! We often advocate for a unifying diagnosis (Occam’s razor), but in people with immunocompromise, it’s important not to disregard Hickam’s dictum; “Patients can have as many diseases as they damn well please!” #Medsky #IDSky #TxIDSky 3161
David Griffin 🦠🧫💉 @drdavidwjg.bsky.social · 15/11/2024Interesting take in @nytimes.com Most of us know that the individual and #publichealth benefits of #vaccines are irrefutable, but we must take the opportunity to communicate differently about vaccines; listen, learn, and leverage #RFKs skepticism for good. www.nytimes.com/2024/11/15/o...nytimes.comOpinion | Can America’s Health Survive Robert F. Kennedy Jr.?What Kennedy gets right. 010
David Griffin 🦠🧫💉 @drdavidwjg.bsky.social · 15/11/2024Welcome! Come one, come all.media.tenor.coma 3d model of the statue of liberty is shown on a websiteALT: a 3d model of the statue of liberty is shown on a website 020
David Griffin 🦠🧫💉 @drdavidwjg.bsky.social · 15/11/2024Super pleased to receive an award for our research on barriers to #SOT for people with #HIV among clinicians and consumers in Australia. #IDSky #HIVSky #HealthEquity 2340
Reposted by David Griffin 🦠🧫💉Ilan Schwartz @germhuntermd.bsky.social · 15/11/2024Y’all are going to need some infectious diseases experts #IDSky Starter Packs IDSky 1 go.bsky.app/LnAQjdq IDSky 2 go.bsky.app/JNfSvQT IDSky 3 go.bsky.app/FeogT7o IDSky 4 go.bsky.app/D1zxj4E IDSky 5 go.bsky.app/NgGSPeF IDSky 6 go.bsky.app/22VBL8z #MedSkymedia.tenor.coma man in a lab coat says no reason in front of a wall of cardsAlt: a man in a lab coat says “no reason” 42346121
David Griffin 🦠🧫💉 @drdavidwjg.bsky.social · 15/11/2024Yeah, I’d rather not have billion/trillionaires trying to exert unbridled influence over what I and others think. Hi Friend! 🫶🏼 020
David Griffin 🦠🧫💉 @drdavidwjg.bsky.social · 14/11/2024Thanks! That’s a great resource. 👍🏼 Glad to be included 🥳 010
David Griffin 🦠🧫💉 @drdavidwjg.bsky.social · 14/11/2024Rolling out the Quebecois red carpet! Merci! 010