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This cohort study examines whether receipt of gender-affirming hormone therapy is associated with rates of moderate-to-severe depression in transgender, nonbinary, and gender diverse adults in the US.

Objective Transgender and gender-diverse individuals undergoing estradiol therapy for gender affirmation are typically treated with oral or transdermal estradiol, with transdermal estradiol recommen.....

The mental health of trans, nonbinary and gender-diverse Australians is suffering and getting worse.

AbstractBackground. Increasing numbers of transgender and gender-diverse individuals are seeking initiation of gender-affirming hormone therapy. This align