Tractor-Mix is a GWAS method for admixed cohorts with high relatedness, improving ancestry-specific effect estimation, controlling false positives and boosting power to detect ancestry-enriched loci a...

Polygenic scores (PGS) are widely used for estimating genetic predisposition to complex traits by aggregating the effects of common variants into a single measure. They hold promise in identifying ind...

Standard genome-wide association studies (GWAS) and rare variant burden tests are essential tools for identifying trait-relevant genes. Although these methods are conceptually similar, we show by anal...