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Diego A. Pizzagalli, PhD

@diegopizzagalli.bsky.social
189 followers 48 following 32 posts

Founding Director, Noel Drury, M.D. Institute for Translational Depression Discoveries Distinguished Professor & Noel Drury MD Endowed Chair University of California, Irvine

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Diego A. Pizzagalli, PhD @diegopizzagalli.bsky.social · 10/07/2026
New in Nature Mental Health: our SMART-D precision medicine trial tested biomarkers to guide sertraline vs bupropion in MDD (rdcu.be/fsf2V). Biomarker-positive patients had better symptom trajectories than those without biomarkers (71.4% vs. 42.9% response rates). #Depression #PrecisionPsychiatry
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Diego A. Pizzagalli, PhD @diegopizzagalli.bsky.social · 07/07/2026
20 years after the first Probabilistic Reward Task (PRT) paper, this review highlights a cross-species measure of reward learning—linking anhedonia, depression risk, neural circuitry, and treatment-relevant mechanisms. rdcu.be/fsf29 #Anhedonia #Depression
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Diego A. Pizzagalli, PhD @diegopizzagalli.bsky.social · 17/06/2026
2/2: We are seeking outstanding clinician-scientists and basic and/or translational scientists who share our vision of collaborative team science to advance the understanding, prevention, and treatment of depression. For additional information and to apply, please visit: recruit.ap.uci.edu/JPF10128
recruit.ap.uci.edu
Depression Research Cluster Hire - Senate Faculty, Psychiatry Open Ranks
University of California, Irvine is hiring. Apply now!
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Diego A. Pizzagalli, PhD @diegopizzagalli.bsky.social · 17/06/2026
1/2: Dear colleagues: Due to a flurry of applications received on June 15, we are extending the application deadline to June 22 for two open-rank faculty positions within the Noel Drury, M.D. Institute for Translational Depression Discoveries at UC Irvine.
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Diego A. Pizzagalli, PhD @diegopizzagalli.bsky.social · 14/06/2026
7/7: We are deeply grateful to everyone who attended—many of whom traveled from afar—and to all those whose contributions made this memorable event possible.
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Diego A. Pizzagalli, PhD @diegopizzagalli.bsky.social · 14/06/2026
6/7: The event left us energized and firmly focused on our vision: to fundamentally improve the understanding, treatment, and prevention of this prevalent and debilitating disorder.
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Diego A. Pizzagalli, PhD @diegopizzagalli.bsky.social · 14/06/2026
5/7: emerging technologies, and the social determinants of health. The program also included powerful remarks from individuals with lived experience, Dr. Noel Drury—a distinguished psychiatrist and the Institute’s namesake—and other distinguished speakers.
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Diego A. Pizzagalli, PhD @diegopizzagalli.bsky.social · 14/06/2026
4/7: Our Launch Event (tinyurl.com/y99h4ke9) featured a brilliant keynote lecture by Conor Liston (Cornell University), along with presentations by leading UC Irvine researchers on topics ranging from early-life adversity and adolescent mental health to neurobiology, …
tinyurl.com
Launch Event – Depression Institute
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Diego A. Pizzagalli, PhD @diegopizzagalli.bsky.social · 14/06/2026
3/7: information and computer science, and public health), our goal is to foster interdisciplinary collaborations and accelerate the translation of research discoveries into real-world solutions for individuals living with, or at risk for, depression.
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Diego A. Pizzagalli, PhD @diegopizzagalli.bsky.social · 14/06/2026
2/7: multiple academic schools in a coordinated effort to address depression (depressioninstitute.uci.edu). Bringing together laboratories across 13 departments and seven schools (medicine, biological sciences, engineering, social ecology, social sciences, …
depressioninstitute.uci.edu
Depression Institute
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Diego A. Pizzagalli, PhD @diegopizzagalli.bsky.social · 14/06/2026
1/7: On June 9, we marked a major milestone in mental health research with the formal launch of the Noel Drury, M.D. Institute for Translational Depression Discoveries at the University of California, Irvine—the first institute in the nation to formally unite …
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Diego A. Pizzagalli, PhD @diegopizzagalli.bsky.social · 08/06/2026
We are looking for outstanding clinician-scientists, basic and/or translational scientists who share our vision for collaborative team science to tackle depression. See. recruit.ap.uci.edu/JPF10128 Please repost.
recruit.ap.uci.edu
Depression Research Cluster Hire - Senate Faculty, Psychiatry Open Ranks
University of California, Irvine is hiring. Apply now!
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Diego A. Pizzagalli, PhD @diegopizzagalli.bsky.social · 08/06/2026
Dear colleagues: a reminder that the submission deadline for these two faculty openings (open rank) within the Noel Drury, M.D. Institute for Translational Depression Discoveries (UC Irvine) is June 15, 2026.
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Diego A. Pizzagalli, PhD @diegopizzagalli.bsky.social · 05/05/2026
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Diego A. Pizzagalli, PhD @diegopizzagalli.bsky.social · 05/05/2026
6/6: Details, including priority areas and submission information, are available at: recruit.ap.uci.edu/JPF10128.
recruit.ap.uci.edu
Depression Research Cluster Hire - Senate Faculty, Psychiatry Open Ranks
University of California, Irvine is hiring. Apply now!
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Diego A. Pizzagalli, PhD @diegopizzagalli.bsky.social · 05/05/2026
5/6: After successful faculty recruitments focused on depression for the Department of Neurobiology & Behavior as well as the Department of Biomedical Engineering, we are now offering two open rank faculty positions for the Department of Psychiatry & Human Behavior.
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Diego A. Pizzagalli, PhD @diegopizzagalli.bsky.social · 05/05/2026
4/6: (3) improving the life of individuals with lived experiences.
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Diego A. Pizzagalli, PhD @diegopizzagalli.bsky.social · 05/05/2026
3/6: Its mission is to create a vibrant, inclusive, and interdisciplinary community of scientists and clinicians devoted to (1) fundamentally improving our understanding, treatment and prevention of depression, (2) training the next generation of depression scientists and clinicians, and
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Diego A. Pizzagalli, PhD @diegopizzagalli.bsky.social · 05/05/2026
2/6: In January 2025 we launched this new Institute (depressioninstitute.uci.edu), with the vision to transform our understanding of depression’s origins, treatment, and prevention, while enhancing societal-well being.
depressioninstitute.uci.edu
Depression Institute
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Diego A. Pizzagalli, PhD @diegopizzagalli.bsky.social · 05/05/2026
1/6: Two faculty positions at the Noel Drury, M.D. Institute for Translational Depression Discoveries Delighted to announce that we have two faculty openings for the Noel Drury, M.D. Institute for Translational Depression Discoveries at UC Irvine. The submission deadline is June 15, 2026.
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Reposted by Diego A. Pizzagalli, PhD
Genevieve P. Nowicki, M.S. (she/her) @gepnowicki.bsky.social · 26/08/2025
Excited to share this publication from my work as a research assistant in the lab of @diegopizzagalli.bsky.social . Such an honor to train under this all-star team! www.nature.com/articles/s42...
nature.com
Identification of conserved frontal neurophysiological markers of cognitive flexibility in humans and rats - Communications Biology
Integration of a probabilistic reversal learning task aligned between humans and rodents demonstrates concordant behavioral, computational, and neurophysiological measures of cognitive flexibility bet...
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Diego A. Pizzagalli, PhD @diegopizzagalli.bsky.social · 18/07/2025
Progressive BP would certainly be preferred over sucrose preference or forced swim test.
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Diego A. Pizzagalli, PhD @diegopizzagalli.bsky.social · 18/06/2025
So well deserved, Shiba! Well done
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Diego A. Pizzagalli, PhD @diegopizzagalli.bsky.social · 17/04/2025
And to clarify: our search committees are very grateful and rather energized by the many outstanding applications we have already received; this extension is just to provide more time to applicants who might be navigating challenging situations.
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Diego A. Pizzagalli, PhD @diegopizzagalli.bsky.social · 15/04/2025
3/3: Charlie Dunlop School of Biological Sciences (Assistant/Associate Professor): recruit.ap.uci.edu/JPF09508 Henry Samueli School of Engineering (Assistant/Associate Professor): recruit.ap.uci.edu/JPF09510
recruit.ap.uci.edu
Open Rank Cluster Hire in Depression Research
University of California, Irvine is hiring. Apply now!
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Diego A. Pizzagalli, PhD @diegopizzagalli.bsky.social · 15/04/2025
2/3: For more information about the research priorities and submission guidelines, see the following links: School of Medicine Position (Open Rank): recruit.ap.uci.edu/JPF09507
recruit.ap.uci.edu
Open-Rank Faculty Cluster Hire in Depression Research
University of California, Irvine is hiring. Apply now!
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Diego A. Pizzagalli, PhD @diegopizzagalli.bsky.social · 15/04/2025
1/3: in light of recent developments across the US academic landscape, which might have presented challenges to colleagues, we decided to extend the submission deadline for our three faculty openings focused on depression until May 14, 2025.
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Diego A. Pizzagalli, PhD @diegopizzagalli.bsky.social · 09/04/2025
2/2: Most critically, this marker generalized across independent studies (EMBARC and CANBIND) yielding important generalizability. Details at jamanetwork.com/journals/jam...
jamanetwork.com
Generalizability of Treatment Outcome Prediction Across Antidepressant Trials
This prognostic study examines whether neuroimaging and clinical features predict response to sertraline and escitalopram in patients with major depressive disorder across 2 multisite studies using ma...
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Diego A. Pizzagalli, PhD @diegopizzagalli.bsky.social · 09/04/2025
1/2: Important new findings by Peter Zhukovsky, a former postdoc in the lab and now faculty at CAMH, who identified a neural (rsfMRI) marker that predicted SSRI treatment response.
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Diego A. Pizzagalli, PhD @diegopizzagalli.bsky.social · 07/04/2025
2/2: To be considered, applicants should submit their material electronically at: School of Medicine Position: recruit.ap.uci.edu/JPF09507 Charlie Dunlop School of Biological Sciences: recruit.ap.uci.edu/JPF09508 Henry Samueli School of Engineering: recruit.ap.uci.edu/JPF09510
recruit.ap.uci.edu
Open-Rank Faculty Cluster Hire in Depression Research
University of California, Irvine is hiring. Apply now!
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Diego A. Pizzagalli, PhD @diegopizzagalli.bsky.social · 07/04/2025
🧪🧠 1/2: Final reminder that the deadline for the faculty cluster hire (3 faculty positions) within the newly established Noel Drury, M.D. Institute for Translational Depression Discoveries at UC Irvine is April 9, 2025.
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Diego A. Pizzagalli, PhD @diegopizzagalli.bsky.social · 20/03/2025
Dear colleagues & friends: In light of recent announcements, the search committees and I wanted to reassure potential candidates that the faculty search (three faculty openings) for our new UCI Depression Institute continues as planned. Please circulate
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Diego A. Pizzagalli, PhD @diegopizzagalli.bsky.social · 20/03/2025
beautiful and impactful review paper!
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