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Diego A. Pizzagalli, PhD

@diegopizzagalli.bsky.social

Founding Director, Noel Drury, M.D. Institute for Translational Depression Discoveries Distinguished Professor & Noel Drury MD Endowed Chair University of California, Irvine

Posts Replies Media

Diego A. Pizzagalli, PhD @diegopizzagalli.bsky.social · 10/07/2026

New in Nature Mental Health: our SMART-D precision medicine trial tested biomarkers to guide sertraline vs bupropion in MDD (rdcu.be/fsf2V). Biomarker-positive patients had better symptom trajectories than those without biomarkers (71.4% vs. 42.9% response rates). #Depression #PrecisionPsychiatry

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Diego A. Pizzagalli, PhD @diegopizzagalli.bsky.social · 07/07/2026

20 years after the first Probabilistic Reward Task (PRT) paper, this review highlights a cross-species measure of reward learning—linking anhedonia, depression risk, neural circuitry, and treatment-relevant mechanisms. rdcu.be/fsf29 #Anhedonia #Depression

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Diego A. Pizzagalli, PhD @diegopizzagalli.bsky.social · 14/06/2026

7/7: We are deeply grateful to everyone who attended—many of whom traveled from afar—and to all those whose contributions made this memorable event possible.

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Diego A. Pizzagalli, PhD @diegopizzagalli.bsky.social · 05/05/2026

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