iiinova — where your digital self keeps evolving

Matthias D'hooghe @dhooghe-group.bsky.social · 14/09/2026

Last week, Fien and Felien presented their PhD work at the International Conference on Green Chemistry in Lisbon (CO2 chemistry, Fien Vanhecke) and the International Symposium on Medicinal Chemistry in Basel (Pemafibrate synthesis, Felien Morlion) @synbioc.bsky.social, @fwovlaanderen.bsky.social

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Matthias D'hooghe @dhooghe-group.bsky.social · 24/08/2026

Congratulations to Dr. Kato Bredael, who successfully defended her PhD thesis on beta-lactams last week 🥳 Thanks to the jury members for their input, and to the team of Prof. Gobec (Ljubljana) for the collaboration! @synbioc.bsky.social @fbwugent.bsky.social @fwovlaanderen.bsky.social #antibiotics

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Matthias D'hooghe @dhooghe-group.bsky.social · 31/07/2026

The first paper of Kato Bredael's PhD work on monocyclic β-lactams is published in 'Chemistry - an Asian Journal': doi.org/10.1002/asia... - in collaboration with Prof. Gobec and Prof. Hrast (University of Ljubljana). @synbioc.bsky.social @fbwugent.bsky.social @wiley.com #antibiotics

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Matthias D'hooghe @dhooghe-group.bsky.social · 02/06/2026

Our PhD student Emma Vandenheede presenting her research on the formation of CO2-based azaheterocycles at the #RRB2026 conference in Leuven, Belgium 🙂 @synbioc.bsky.social; @fbwugent.bsky.social

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Matthias D'hooghe @dhooghe-group.bsky.social · 16/04/2026

Two weeks ago, Alexandre Bringuet – a Master student @chimieparistechpsl.bsky.social – joined our team for a five-month internship. He will study CO2 capture reactions for the construction of new azaheterocycles, supervised by our PhD student Fien Vanhecke. Welcome Alexandre! @synbioc.bsky.social

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Matthias D'hooghe @dhooghe-group.bsky.social · 14/04/2026

Last week, our PhD student Maya Boone presented her work on the preparation of curcuminoid-lanthanide complexes at the 15th Inorganic and Bioinorganic Chemistry Conference in Lisbon 🙂, @synbioc.bsky.social, @fbwugent.bsky.social

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Matthias D'hooghe @dhooghe-group.bsky.social · 26/03/2026

Need Pemafibrate? Check out our new route to this PPARα agonist, allowing for the efficient and low-cost preparation of enantiopure Pema at the multigram scale – developed by our PhD student Felien Morlion: dx.doi.org/10.1002/open.... @synbioc.bsky.social @fbwugent.bsky.social

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Matthias D'hooghe @dhooghe-group.bsky.social · 16/12/2025

Our SynBioC PhD student Ulrike Ronse presenting our work related to HDAC6 inhibitor development at the MedChem 2025 meeting in Ghent (Dec. 15th) 😀 @synbioc.bsky.social @fbwugent.bsky.social @crighent.bsky.social

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Reposted by Matthias D'hooghe

RRB Conference @rrbconference.bsky.social · 31/10/2025

#RRB2026 1-3 June in Leuven Innovating Today for a Sustainable Tomorrow! @chsteven.bsky.social @pedrofardim.bsky.social @fbwugent.bsky.social @synbioc.bsky.social Check our latest newsletter mailchi.mp/7e723ddba897...

Innovating today for a sustainable tomorrow
RRB2026 Conference from 1-3 June 2026 in Leuven, Belgium
Quotes from Prof Chris Stevens and Prof Pedro Fardim.

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Matthias D'hooghe @dhooghe-group.bsky.social · 03/09/2025

New paper alert 📢 Our review article on lanthanide nucleotide coordination polymers for sensing applications is published in Coordination Chemistry Reviews: doi.org/10.1016/j.cc... @synbioc.bsky.social @fbwugent.bsky.social @elsevierconnect.bsky.social

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Matthias D'hooghe @dhooghe-group.bsky.social · 02/09/2025

Our former @synbioc.bsky.social postdoc Goran Poje presenting his research on harmine-curcuminoid hybrids at the EFMC-ASMC 2025 conference in Porto 😀 @fbwugent.bsky.social @fwovlaanderen.bsky.social @euromedchem.bsky.social

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Matthias D'hooghe @dhooghe-group.bsky.social · 02/09/2025

Our @synbioc.bsky.social PhD student Kato Bredael presenting her research on monocyclic β-lactam antibacterials at the EFMC-ASMC 2025 conference in Porto 😀 @fbwugent.bsky.social @fwovlaanderen.bsky.social @euromedchem.bsky.social

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Matthias D'hooghe @dhooghe-group.bsky.social · 26/05/2025

Our review paper on the synthesis and antibacterial properties of C4-functionalized β-lactams is published in @wiley.com: doi.org/10.1002/cmdc... @synbioc.bsky.social @fbwugent.bsky.social @chsteven.bsky.social

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Matthias D'hooghe @dhooghe-group.bsky.social · 15/05/2025

Our PhD student Ulrike Ronse presenting a decade of work on HDAC6 in our group at the Medicinal Chemistry Frontiers conference 2025 in Chicago 😀 @synbioc.bsky.social @fbwugent.bsky.social

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Matthias D'hooghe @dhooghe-group.bsky.social · 07/05/2025

Check out our new paper on 3-imino-β-lactam chemistry, published in J. Org. Chem.: pubs.acs.org/doi/full/10.... @pubs.acs.org @synbioc.bsky.social @chsteven.bsky.social @fbwugent.bsky.social

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Reposted by Matthias D'hooghe

SynBioC @synbioc.bsky.social · 01/04/2025

#SynBioC Proud about our SynBioC team who participated at the Sofico Ghent Half Marathon last Sunday! We love: "Work hard, play hard" @chsteven.bsky.social @dhooghe-group.bsky.social @smangelinckx.bsky.social @thegreenchemlab.bsky.social

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Reposted by Matthias D'hooghe

Ash Jogalekar @ashjogalekar.bsky.social · 25/03/2025

New post: I wrote about a recent PROTAC linker design study that drives home the thoroughness with which you have to experimentally and computationally investigate linker flexibility and properties. It's a great role model for practitioners in the field. medchemash.substack.com/p/the-variet...

medchemash.substack.com

The varieties of VHL linker experience

Or why meticulous experimental and computational characterization are integral to good PROTAC design

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Reposted by Matthias D'hooghe

Universität Bern @unibe.ch · 25/03/2025

Significant progress in sustainable chemistry: researchers from the #unibern and the RIKEN Institute have been able to produce organic #molecules using a chemical reaction based on the sustainable metals #sodium and #iron: mediarelations.unibe.ch/media_releas... @evaheviagroup.bsky.social

mediarelations.unibe.ch

Sustainable chemistry: producing molecules more environmentally friendly

Researchers from the University of Bern and the RIKEN research institute in Japan have made a significant advance in sustainable chemistry. They have succeeded in producing organic molecules through a...

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Matthias D'hooghe @dhooghe-group.bsky.social · 10/02/2025

New paper! Our work on cancer cell cytotoxic benzothiazepanes (part 3), in collaboration with the Rega Institute @kuleuven.bsky.social, is published in J. Heterocyclic Chem.: dx.doi.org/10.1002/jhet... @fbwugent.bsky.social @wiley.com #curcumin

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Matthias D'hooghe @dhooghe-group.bsky.social · 17/01/2025

New Paper Alert! See our joint SynBioC – VIB-CMB work on #HDAC6 ubiquitin-binding domain inhibitors published in Eur. J. Med. Chem. doi.org/10.1016/j.ej... @elsevierconnect.bsky.social, with @rjharding.bsky.social, KU Leuven, @csbugent.bsky.social, K. Van Hecke. @fbwugent.bsky.social

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Reposted by Matthias D'hooghe

Matt Saucier @mattsaucier.bsky.social · 13/01/2025

This #OrgLett cover by Guillermo Correa Otero demonstrates human error in mass spec report checking. Instead use CheckAMM! Editorial by EIC Marisa Kozlowski introducing CheckAMM: pubs.acs.org/doi/10.1021/... What @christmann.bsky.social found checking AMM reports: pubs.acs.org/doi/10.1021/...

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Reposted by Matthias D'hooghe

Arthur Gessler @arthurobuntspecht.bsky.social · 22/12/2024

Researchers spend approximately 45% of their time on administrative activities related to #grants rather than actual #research. The current #competition in research #funding has significant drawbacks; evidence-based improvements of the funding system are required: www.pnas.org/doi/10.1073/...

pnas.org

The costs of competition in distributing scarce research funds | PNAS

Research funding systems fundamentally influence how science operates. This paper aims to analyze the allocation of competitive research funding fr...

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Matthias D'hooghe @dhooghe-group.bsky.social · 11/12/2024

Teambuilding activity at the Christmas market in Ghent 😀

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Matthias D'hooghe @dhooghe-group.bsky.social · 09/12/2024

Congratulations to our new SynBioC doctor Katarina Magdalenic for the excellent work on curcuminoids, and many thanks to Prof. Zrinka Rajic from the University of Zagreb for acting as an external jury member!

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Matthias D'hooghe @dhooghe-group.bsky.social · 25/11/2024

It was a pleasure to host Prof. Annette Bayer from the Artic University of Norway today, who gave a very inspiring lecture about stereoselective CO2 fixation and beta-lactamase inhibitor design

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