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Matt Saucier

@mattsaucier.bsky.social
160 followers 176 following 149 posts

Managing Editor at ACS for JOC/OrgLett/OPR&D/ACS Catalysis. I also handle @JOC_OL on X/Twitter account ( x.com/JOC_OL )--what you are used to seeing there, you can find here! Views are my own. www.linkedin.com/in/mattsaucier15

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Matt Saucier @mattsaucier.bsky.social · 12/03/2026
Next week!! The JACS Symposium: CSJ Spring Meeting is an inspiring full-day, in-person symposium spotlighting cutting-edge research in organic, inorganic, polymer, and materials chemistry. pubs.acs.org/JACS-Symposi...
pubs.acs.org
ACS150 JACS Symposium Series: CSJ Spring Meeting
Join leading chemists, researchers, and journal editors in Funabashi, Japan, as we celebrate 150 years of the American Chemical Society, chemical discovery, and explore the future of scientific collab...
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Matt Saucier @mattsaucier.bsky.social · 12/03/2026
Join leading chemists, a Nobel Laureate, researchers, and journal editors in Jeju Island, Republic of Korea, as we celebrate 150 years of ACS, chemical discovery, and explore the future of scientific collaboration pubs.acs.org/JACS-Symposi...
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Matt Saucier @mattsaucier.bsky.social · 17/02/2026
Congratulations to #OrgLett Executive Editor Margaret Brimble on being named Honorary Fellow of the RSC! We are honored to have you and several other 2026 Honorary Fellows on our teams at ACS www.rsc.org/news/2026-ho...
rsc.org
Seven world-class scientists awarded Honorary Fellowships
The Royal Society of Chemistry is proud to announce that seven of the world's most influential scientists have been awarded Honorary Fellowships.
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Matt Saucier @mattsaucier.bsky.social · 02/02/2026
ACS Industry Insider and OPR&D have teamed up to bring some Lessons Learned in Organic Process Chemistry to the forefront of discussion. Our webinar with Yuhei Yamamoto showcased how even elevation of a CDMO can affect route optimization! axial.acs.org/chemical-eng...
axial.acs.org
Hard-Won Lessons from Industrial Chemistry Failures | ACS Publications Chemistry Blog
A collection of candid case studies reveals how industrial chemists diagnose failures and redesign processes with clarity and purpose.
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Matt Saucier @mattsaucier.bsky.social · 13/01/2026
Truly never out of style! #JOrgChem celebrates the latest physical organic chemistry research with nearly 100 articles in this Special Issue. From quantum tunneling to catalyst design revealing how structure, energy, and environment drive reactivity! pubs.acs.org/page/joceah/...
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Matt Saucier @mattsaucier.bsky.social · 13/01/2026
🚨 Call for Short Papers – Communications & Technical Notes Have a breakthrough that doesn’t fit a full-length article? #OPRD is now accepting Communications and Technical Notes—short, focused papers designed to move ideas forward faster. 👉 axial.acs.org/organic-chem...
axial.acs.org
Call For Papers: Communications & Technical Notes in OPR&D | ACS Publications Chemistry Blog
Have a short story to share, or a new protocol that doesn’t fit into a standard full Article? OPR&D is putting out this open Call for Short Papers, welcoming submissions as Communications or Technical...
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Matt Saucier @mattsaucier.bsky.social · 13/01/2026
Submit your Lunar New Year themed covers celebrating the Year of the Horse! 🎆 Submissions in process until February 10 will be considered. Only a few will publish on the front cover an an issue of #OrgLett! Check out last year's covers featured here ➡️ axial.acs.org/organic-chem...
axial.acs.org
Highlighting Chinese Chemists in Organic Letters: Chinese New Year Cover Series, 2025 China Collection, and All-Star Academy Webinar | ACS Publications Chemistry Blog
Join ACS Publications in celebrating China’s leading researchers, cultural heritage, and impactful work published in the journal.
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Matt Saucier @mattsaucier.bsky.social · 30/12/2025
This special collection showcases impactful work supported by the ACS Petroleum Research Fund (PRF) over the past 25 years, highlighting advances in catalysis, energy, and sustainability that span inorganic, organic, and organometallic chemistry. pubs.acs.org/page/vi/cele...
pubs.acs.org
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Matt Saucier @mattsaucier.bsky.social · 05/12/2025
Sign up for our ACS Publications Industry Webinar where we will have #OPRD author Yuhei Yamamoto describe a real-world case study on scale-up of Suzuki-Miyaura couplings. December 11, 2025 at 9 AM Japan Standard Time (December 10, 2025 at 7 PM ET / 4 PM PT) access.acspubs.org/SuzukiMiyaur...
access.acspubs.org
ACS Publications Industry Webinar: Behind the Failures of Suzuki–Miyaura Coupling Scale-Up: A Real-World Case Study
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Matt Saucier @mattsaucier.bsky.social · 05/12/2025
Safety First in Organic Chemistry! ⚠️ #OrgLett published its first "Safety Letter" by Garg, Zhao, and co-workers, spotlighting IBX—a widely used oxidant with explosive potential. Read the Safety Letter and Editorial in this week's issue: pubs.acs.org/toc/orlef7/2...
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Matt Saucier @mattsaucier.bsky.social · 04/12/2025
Submit your nominations today for the Organic and Inorganic Lectureship Awards! Winners will receive an honorarium, plaque, and travel to ACS Fall 2026 in Chicago, IL, to present their outstanding work. axial.acs.org/organic-chem...
axial.acs.org
Organic and Inorganic Chemistry Lectureships and Awards | ACS Publications Chemistry Blog
Explore both current and past journal lectureships and awards from ACS Publications' Organic and Inorganic portfolio.
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Matt Saucier @mattsaucier.bsky.social · 04/12/2025
Time is running out! ⏲️ Submit your manuscript by Dec 31 to #JOrgChem or #Biochemistry for this joint Special Issue featuring the chemistry and biology of peptides. Learn more and submit here 👉 axial.acs.org/biology-and-...
axial.acs.org
Call For Papers: Chemistry and Biology of Peptides | ACS Publications Chemistry Blog
This Special Issue will celebrate the chemistry and biology of peptides, from synthesis, to structure and modifications, to biology and applications, and finally to degradation. Submit your manuscript...
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Matt Saucier @mattsaucier.bsky.social · 01/12/2025
Unlocking the secrets of GH161 enzymes! 🧬 Using cryo-EM, Moulis, Cioci, & co-workers reveal how β-glucan phosphorylases reshape during catalysis—shedding light on the molecular choreography of GH-Q clan enzymes #Biocatalysis #ACSCatalysis @cathleencrudden.bsky.social pubs.acs.org/doi/10.1021/...
pubs.acs.org
Structural and Functional Dissection of GH161 β-Glucan Phosphorylases: Molecular Specificities and Dynamics of Catalysis of Dimeric GH-Q Enzymes
In the CAZy classification of carbohydrate-active enzymes, the GH-Q clan regroups three distantly related glycoside hydrolase (GH) families: GH94, GH149, and GH161. These families contain glycoside ph...
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Matt Saucier @mattsaucier.bsky.social · 01/12/2025
The ACS GCI PR Industry Awards spotlight the best in sustainable/green chemistry innovation across the pharma industry and allied industrial partners. Submit your nomination by Dec. 8! ➡️ acsgcipr.org/funding-awar...
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Matt Saucier @mattsaucier.bsky.social · 01/12/2025
Copper–Iron catalysis unlocks efficient cross-coupling of sterically hindered sulfonamides with (hetero)aryl chlorides & alkyl halides in #OrgLett #EditorsChoice ✅ Diverse substrate scope ✅ Gram-scale ✅ 10 sulfonamide drugs synthesized Read more 👉 pubs.acs.org/doi/10.1021/...
pubs.acs.org
Copper–Iron-Catalyzed Cross-Coupling of ortho-Substituted Sulfonamides with Sterically Hindered (Hetero)aryl Chlorides and Alkyl Halides: Synthesis of Sulfonamide Drugs
We describe for the first time an effective copper–iron-catalyzed cross-coupling strategy that enables the reaction for a diverse array of ortho-substituted primary (hetero)aryl and aliphatic sulfonam...
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Matt Saucier @mattsaucier.bsky.social · 12/11/2025
🚨 Call for Papers! Ready to reshape the future of organic synthesis? Submit to our Special Issue: “Skeletal Editing, Molecular Metamorphosis & Structural Reprogramming” jointly hosted by #OrgLett & #JOrgChem 📅 Deadline: June 1, 2026 axial.acs.org/organic-chem...
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Matt Saucier @mattsaucier.bsky.social · 11/11/2025
In situ TEM doesn't get the full picture. Atomic-resolution imaging is powerful, but sub-nanosecond catalyst dynamics remains difficult. This #EditorsChoice #ACSCatalysis Viewpoint shows why we need more than TEM by Tibor Szilvási pubs.acs.org/doi/10.1021/...
pubs.acs.org
Temporal Resolution of In Situ TEM Limits the Characterization of Catalyst Site Dynamics
In situ transmission electron microscopy (TEM) provides a means for capturing atomic-resolution micrographs under reactive environments and has been widely employed to identify active site candidates ...
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Matt Saucier @mattsaucier.bsky.social · 07/11/2025
Nominate work for the #JOrgChem 2026 Outstanding Paper of the Year Award by Dec 31! The award winner will receive: - $2000 USD prize - Complimentary travel and registration to ACS Fall 2026 in Chicago to deliver the award lecture - Award plaque americanchemical.co1.qualtrics.com/jfe/form/SV_...
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Matt Saucier @mattsaucier.bsky.social · 07/11/2025
Sign up for our ACS Publications Industry Webinar where we will have Amanda Stahl (Amgen) describe the fascinating process development of a key Sotorasib intermediate. Nov 11, 2025 at 12:00 noon (EST) access.acspubs.org/Rac4Process
access.acspubs.org
ACS Publications Industry Webinar: Lessons in Rac-4 Process Enhancement for Sotorasib
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Matt Saucier @mattsaucier.bsky.social · 03/11/2025
Check out this CF2 synthon enabled by dual Rh-Zn catalysis in #ACSCatalysis #EditorsChoice pubs.acs.org/doi/10.1021/...
pubs.acs.org
Asymmetric Diamination of the In Situ Generated Difluoroenol Species Using Azocarboxamides as an N Source
The Rh2(esp)2 and Zn(II)-bisoxazoline (BOX) complex-cocatalyzed asymmetric diamination of in situ generated difluoroenol species with azocarboxamides has been disclosed. This reaction features a formal [3 + 2]-cycloaddition reaction using difluoroenol intermediate as a C2 synthon, providing an efficient and robust approach for the synthesis of difluorinated imidazolidin-2-ones in good yields with high to excellent stereoselectivity (up to 95% ee). This method offers a complementary approach for the direct assembly of chiral difluoromethylene incorporated heterocycles by introducing in situ formed difluoroenol species as a practical C2 synthon rather than using presynthesized gem-difluoroalkenes. With this protocol, further synthetic applications in fluorine chemistry could be envisioned through the strategic interception of difluoroenol via cycloaddition reactions with appropriate partners.
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Matt Saucier @mattsaucier.bsky.social · 31/10/2025
Submit your nominations for the ACS Catalysis Lectureship Award by Dec 31! The award winner will receive: - $1000 USD prize - Complimentary travel and registration to ACS Fall 2026 in Chicago to deliver the award lecture - Award plaque americanchemical.co1.qualtrics.com/jfe/form/SV_...
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Matt Saucier @mattsaucier.bsky.social · 31/10/2025
Nominate Articles for the #OPRD 2026 Outstanding Paper of the Year Award by Dec 31! The award winner will receive: - $2000 USD prize - Complimentary travel and registration to ACS Fall 2026 in Chicago to deliver the award lecture - Award plaque americanchemical.co1.qualtrics.com/jfe/form/SV_...
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Matt Saucier @mattsaucier.bsky.social · 31/10/2025
Nominate Letters for the #OrgLett 2026 Outstanding Paper of the Year Award by Dec 31! The award winner will receive: - $2000 USD prize - Complimentary travel and registration to ACS Fall 2026 in Chicago to deliver the award lecture - Award plaque americanchemical.co1.qualtrics.com/jfe/form/SV_...
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Matt Saucier @mattsaucier.bsky.social · 24/10/2025
🚨Special Issue Alert🚨 π-Conjugated Molecules & Materials in #OrgLett Honoring August Kekulé and Eric Clar, this Special Issue showcases everything from CPL and optoelectronics, to nonbenzenoid aromatic compounds and nanohoops. pubs.acs.org/page/orlef7/...
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Reposted by Matt Saucier
ACS Publications @pubs.acs.org · 23/10/2025
Upcoming: ACS150 JACS Symposium: Expanding Horizons of Nanoscience & Energy Celebrating 150 years of ACS and chemical discovery with two days of cutting-edge science in nanoscience and energy. 📍 @ethz.ch, Switzerland 📅 12-13 January 2026 Apply to attend: buff.ly/wwbZ5c6
Apply to attend ACS150 JACS Symposium Series: ETH Zürich - Expanding Horizons of Nanoscience & Energy

ETH Zurich, Switzerland  
12-13 January 2026
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Matt Saucier @mattsaucier.bsky.social · 20/10/2025
Another #EditorsChoice article published in #JOrgChem! Learn more about cyclopropane annulation to form elusive iminodihydrothiophene derivatives from Maity and co-workers pubs.acs.org/doi/10.1021/...
pubs.acs.org
[3 + 2] Annulation of Donor–Acceptor Cyclopropanes with Ammonium Thiocyanate: Interrupted Cascade Leads to Elusive Iminodihydrothiophene Derivatives
A zinc iodide-mediated [3 + 2] cyclization between donor–acceptor cyclopropanes and ammonium thiocyanate has been developed to afford 2-imino-tetrahydrothiophene derivatives under mild conditions. Sub...
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Matt Saucier @mattsaucier.bsky.social · 13/10/2025
Editors' Choice alert! Plunkett, et al. in #OrgLett: A Simplified, One-Pot, Procedure for the Deoxygenative Alkylation of Aryl Bromides pubs.acs.org/doi/10.1021/...
pubs.acs.org
A Simplified, One-Pot, Procedure for the Deoxygenative Alkylation of Aryl Bromides
Advancements in the field of C(sp2)–C(sp3) cross-coupling using alcohols as feedstocks have resulted in widespread adoption in analogue synthesis. Using high-throughput experimentation, an in situ alc...
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Matt Saucier @mattsaucier.bsky.social · 10/10/2025
Congrats and thanks to Neil Garg, Ralph Zhao, and co-workers for publishing #OrgLett 's first Safety Letter: Evaluation of the Popular Oxidant 2-Iodobenzoic Acid (IBX) pubs.acs.org/doi/10.1021/...
pubs.acs.org
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Matt Saucier @mattsaucier.bsky.social · 09/10/2025
Conducting impactful research for the betterment of the world and our society ought not to be overshadowed by the dangers and risks its practitioners take on. -- Read about our Safety Letter initiative at #OrgLett pubs.acs.org/doi/10.1021/...
pubs.acs.org
Emphasizing Safety in Publications at Organic Letters: The Safety Letter
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Matt Saucier @mattsaucier.bsky.social · 03/10/2025
"Failure is the mother of success" -- Read case studies highlighting the knowledge gained from failures and unexpected results in this Lessons Learned in Organic Process Chemistry Special Issue in #OPRD @pubs.acs.org pubs.acs.org/page/oprdfk/...
pubs.acs.org
Lessons Learned in Organic Process Chemistry
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Matt Saucier @mattsaucier.bsky.social · 30/09/2025
Read about this new photocatalyzed cyclization and HAT reaction published in #JOrgChem by Ghosh/Konig and coworkers. Selected for #EditorsChoice pubs.acs.org/doi/10.1021/...
pubs.acs.org
Photo-Catalyzed Synthesis of Indanones from Aromatic Aldehydes and Terminal Alkynes
Indanones are key structural motifs in pharmaceuticals and bioactive natural products, making their efficient synthesis a subject of continued interest. Conventional methods typically rely on transiti...
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Matt Saucier @mattsaucier.bsky.social · 30/09/2025
NSF-funded reproducibility in homogeneous catalysis workshop coming Jan 2026. Check out the webinars coming up on Oct 22 and 29 with ACS Catalysis EIC Cathleen Crudden speaking at the Oct 22 session. www.acs-catalysis.org/post/input-n...
acs-catalysis.org
Input needed in homogenous catalysis
A team is organizing the Workshop on Reproducibility in Homogeneous Catalysis in January 2026. By bring together community members, the workshop aims to identify challenges and opportunities in homoge...
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Reposted by Matt Saucier
Matt Saucier @mattsaucier.bsky.social · 13/01/2025
Wait, we (@S_Yoshida_Lab) made thioxanthones?! Double aryne insertion into thioureas + simple hydrolysis = super functionalized thioxanthones. Who saw that coming? #AryneChemistry #OpenAccess #OrgLett #ChemSky pubs.acs.org/doi/10.1021/...
pubs.acs.org
Thioxanthone Synthesis from Thioureas through Double Aryne Insertion into a Carbon-Sulfur Double Bond
Thioxanthone synthesis from o-silylaryl triflates and thioureas is disclosed. Double aryne insertion into the C═S double bond of thioureas and subsequent hydrolysis realized the facile preparation of ...
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Matt Saucier @mattsaucier.bsky.social · 26/08/2025
🆕 Catalyst free reductive amination with non toxic, cheap NaH₂PO₂!♻️ 16 amine–carbonyl combos covered, tunable conditions & kinetic insights. Check out the #JOrgChem guide to substrates📘 👉 doi.org/10.1021/acs.... @ChusovGroup @pubs.acs.org
doi.org
Reductive Amination Reactions Using Sodium Hypophosphite: a Guide to Substrates
The reactions of reductive amination are of paramount importance as tools of synthetic organic chemistry. Recently, the applicability of sodium hypophosphite as a promising reductant for such reaction...
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Matt Saucier @mattsaucier.bsky.social · 22/08/2025
Do you work at the interface of chemistry and biology in the field of peptides? #JOrgChem and #Biochemistry have put out a Call for Papers related to all things peptides! Submission deadline: Dec 31, 2025 axial.acs.org/biology-and-...
axial.acs.org
Call For Papers: Chemistry and Biology of Peptides | ACS Publications Chemistry Blog
This Special Issue will celebrate the chemistry and biology of peptides, from synthesis, to structure and modifications, to biology and applications, and finally to degradation. Submit your manuscript...
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Matt Saucier @mattsaucier.bsky.social · 22/08/2025
This month's #OPRD Items of Interest is out! pubs.acs.org/doi/10.1021/...
pubs.acs.org
Some Items of Interest to Process R&D Chemists and Engineers
You have not visited any articles yet, Please visit some articles to see contents here.
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Matt Saucier @mattsaucier.bsky.social · 22/08/2025
Congrats to the organic lectureship award winners! Hsiao-Wu Hsieh - axial.acs.org/organic-chem... Rui Shang - axial.acs.org/catalysis/me... Gabriel Schaefer - axial.acs.org/organic-chem... (lecture by Michael Willis) Jacquelyne Read - axial.acs.org/organic-chem...
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Reposted by Matt Saucier
Hirohisa Ohmiya @hirohisaohmiya.bsky.social · 28/05/2025
Just published in #OrgLett ! We report an NHC/organic photoredox cocatalyzed acyl azolation of styrenes using acyl azoles. Congratulations Kanata and Yamato! doi.org/10.1021/acs....
doi.org
N-Heterocyclic Carbene/Organic Photoredox-Cocatalyzed Acyl Azolation of Alkenes with Acyl Azoles
We have developed the N-heterocyclic carbene/organic photoredox-cocatalyzed acyl azolation of styrenes using acyl azoles. The cooperative action of organic photoredox catalysis and NHC catalysis enabl...
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Matt Saucier @mattsaucier.bsky.social · 02/05/2025
Check out our latest initiatives to celebrate Chinese researchers publishing in #OrgLett! Learn about our Chinese New Year Covers Series, 2025 Collection of 36 Letters from China, ACS All-Star Academy, and more! axial.acs.org/organic-chem...
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Matt Saucier @mattsaucier.bsky.social · 02/05/2025
A very big congrats to the #OPRD winners of the Outstanding Publication of the Year Award, co-sponsored by the ACS Division of Organic Chemistry: Dr. Hsiao-Wu Hsieh and colleagues! axial.acs.org/organic-chem...
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Matt Saucier @mattsaucier.bsky.social · 02/05/2025
A very big congrats to the #JOrgChem winners of the Outstanding Publication of the Year Award, co-sponsored by the ACS Division of Organic Chemistry: Prof. Jacquelyne A. Read and colleagues! axial.acs.org/organic-chem...
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Matt Saucier @mattsaucier.bsky.social · 01/05/2025
A very big congrats to the #OrgLett winner of the Outstanding Publication of the Year Award, co-sponsored by the ACS Division of Organic Chemistry: Dr. Gabriel Schäfer and colleagues! axial.acs.org/organic-chem...
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Matt Saucier @mattsaucier.bsky.social · 30/04/2025
Check out our latest joint Special Issue between #JOrgChem and #OPRD: Excellence in Industrial Organic Synthesis! This is the third edition of this special issue highlighting the industrially relevant work in organic synthesis today. pubs.acs.org/page/vsi/exc...
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Matt Saucier @mattsaucier.bsky.social · 21/03/2025
Submit your abstracts for Pacifichem 2025! pacifichem.org #OrgLett Executive Editor Margaret Brimble sends this call for abstracts for the Symposium on Peptide Therapeutics and Peptidomimetic. Margaret is one of the organizers along with Severin T. Schneebeli, Rotimi Aluko, and Hidehito Mukai
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Matt Saucier @mattsaucier.bsky.social · 10/03/2025
Recently, #OrgLett has published a series of Chinese New Year-themed covers to celebrate the Year of the Snake, a symbol of wisdom, transformation and renewal in Chinese culture--reflecting both cultural heritage and the vibrant synergy driving the frontiers in org chem of China
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Matt Saucier @mattsaucier.bsky.social · 07/03/2025
Want to learn more about catalytic dehydrogenative polymerization or single-atom-alloy catalysts? Check out these reviews and perspectives recently published in #ACSCatalysis! #chemsky pubs.acs.org/doi/10.1021/... pubs.acs.org/doi/10.1021/...
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Matt Saucier @mattsaucier.bsky.social · 07/03/2025
This #ACSCatalysis cover features nitrogen-directed C(sp3)–H and C(sp2)–H borylation with pinacolborane (HBpin) at near-room temperature using an Ir(cod) catalyst with a spiro-fluorene-indenoindenyl (SFI) ligand [ pubs.acs.org/doi/10.1021/... ]
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Matt Saucier @mattsaucier.bsky.social · 07/03/2025
Reminder! The deadline for submissions to the Physical Organic Chemistry special issue at #JOrgChem is coming up soon: April 1, 2025 axial.acs.org/organic-chem...
axial.acs.org
Call For Papers: Physical Organic Chemistry: Never Out of Style | ACS Publications Chemistry Blog
This Special Issue will showcase the breadth of modern Physical Organic Chemistry and will set the stage for future innovation. Submit your manuscript by April 1, 2025.
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Matt Saucier @mattsaucier.bsky.social · 07/03/2025
Find out more about polymer-supported selenium and organoselenium catalyst design in this recently published #JOrgChem JOCSynopsis! #Chemsky pubs.acs.org/doi/10.1021/...
pubs.acs.org
Polymer-Supported Selenium Affording Opportunities in Catalyst Design
Polymer-supported selenium has been reported as a heterogeneous catalyst that is easily separated from the reaction system, thereby making the recovery and reuse of the catalyst more convenient. However, the utilization of polymer-supported selenium in the preparation of catalysts is not restricted to the aforementioned technical advantages. Recent studies have shown that polymer-supported selenium and small-molecule organoselenium catalysts have significant performance differences, leading to distinct reaction mechanisms, which offer more opportunities for the development of new organic reactions.
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Matt Saucier @mattsaucier.bsky.social · 07/03/2025
This #JOrgChem cover art illustrates the rational protein engineering of the DERA enzyme from Geobacillus sp., resulting in two enantiocomplementary variants: (R)-selective DERAGeo-S185G and (S)-selective DERAGeo-T12I/S185A [ pubs.acs.org/doi/10.1021/... ] #Chemsky
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