- A new single-center study from the Netherlands quantifies the devastating outcomes of the diabetic foot attack: only 48.5% wound closure, 46% major amputation by 12 months, 26% one-year mortality, and 12-month amputation-free survival of just 39.7%. Time is tissue. Our colleagues at St Antonius Hospital in Nieuwegein, the Netherlands, led by Olaf Bakker, have just published a sobering paper in the Journal of Plastic, Reconstructive & Aesthetic Surgery that quantifies what many of us have felt in our bones for years: the diabetic foot attack (DFA) is a devastating clinical event with outcomes that A new single-center study from the Netherlands quantifies the devastating outcomes of the diabetic foot attack: only 48.5% wound closure, 46% major amputation by 12 months, 26% one-year mortality, and 12-month amputation-free survival of just 39.7%. Time is tissue. - -

- We’ve known for a long time that a diabetic foot ulcer (DFU) isn’t just a wound on the bottom of a foot—it’s a massive red flare for a patient’s overall health. But a recent nationwide study in Diabetes Care just put some sobering, and ultimately hopeful, numbers behind that reality. The data from this massive We’ve known for a long time that a diabetic foot ulcer (DFU) isn’t just a wound on the bottom of a foot—it’s a massive red flare for a patient’s overall health. But a recent nationwide study in Diabetes Care just put some sobering, and ultimately hopeful, numbers behind that reality. The data from this massive We’ve known for a long time that a diabetic foot ulcer (DFU) isn’t just a wound on the bottom of a foot—it’s a massive red flare for a patient’s overall health. But a recent nationwide study in Diabetes Care just put some sobering, and ultimately hopeful, numbers behind that reality. The data from this massive - -

- In 2009, California hospitals collectively documented 7,973 lower-extremity amputations in diabetic adults. Dr. Carl Stevens at Harbor-UCLA decided to ask a question most people in medicine had quietly avoided: where do these patients live? The answer, published five years later in Health Affairs, was the kind of finding that is simultaneously obvious in retrospect and In 2009, California hospitals collectively documented 7,973 lower-extremity amputations in diabetic adults. Dr. Carl Stevens at Harbor-UCLA decided to ask a question most people in medicine had quietly avoided: where do these patients live? The answer, published five years later in Health Affairs, was the kind of finding that is simultaneously obvious in retrospect and In 2009, California hospitals collectively documented 7,973 lower-extremity amputations in diabetic adults. Dr. Carl Stevens at Harbor-UCLA decided to ask a question most people in medicine had quietly avoided: where do these patients live? The answer, published five years later in Health Affairs, was the kind of finding that is simultaneously obvious in retrospect and - -

- VIA Keck School News The USC Limb Preservation Program has been awarded an 18-month, $1.43 million grant from the Department of Defense to support an innovative wound-healing program. The group will be studying the effects of stimulating the spleen in people with catastrophic tissue loss to promote the release of anti-inflammatory cells and cytokines. The VIA Keck School News The USC Limb Preservation Program has been awarded an 18-month, $1.43 million grant from the Department of Defense to support an innovative wound-healing program. The group will be studying the effects of stimulating the spleen in people with catastrophic tissue loss to promote the release of anti-inflammatory cells and cytokines. The VIA Keck School News The USC Limb Preservation Program has been awarded an 18-month, $1.43 million grant from the Department of Defense to support an innovative wound-healing program. The group will be studying the effects of stimulating the spleen in people with catastrophic tissue loss to promote the release of anti-inflammatory cells and cytokines. The - -

Current and Future Challenges in Systems Engineering of Intelligent System: from hype to practice using examples from medical device development Speaker: Michael Kremliovsky Bio: Michael Kremliovsky started his academic career in astrophysics and continued in computational topology, complex systems

- A new manuscript published in the Journal of Vascular Surgery sheds light on the alarming prevalence of silent, severe coronary ischemia in patients with diabetic foot ulcers (DFU). The study, “High Prevalence of Silent, Severe Coronary Ischemia in Patients with Diabetic Foot Ulcers,” demonstrates that a significant proportion of DFU patients—without overt history of coronary artery A new manuscript published in the Journal of Vascular Surgery sheds light on the alarming prevalence of silent, severe coronary ischemia in patients with diabetic foot ulcers (DFU). The study, “High Prevalence of Silent, Severe Coronary Ischemia in Patients with Diabetic Foot Ulcers,” demonstrates that a significant proportion of DFU patients—without overt history of coronary artery A new manuscript published in the Journal of Vascular Surgery sheds light on the alarming prevalence of silent, severe coronary ischemia in patients with diabetic foot ulcers (DFU). The study, “High Prevalence of Silent, Severe Coronary Ischemia in Patients with Diabetic Foot Ulcers,” demonstrates that a significant proportion of DFU patients—without overt history of coronary artery - -

- A few weeks ago, we launched The ZIP Code Lottery — a data narrative showing how amputation rates in Los Angeles County track almost perfectly with poverty, not clinical severity. It struck a nerve. The response told us something important: people want to see the data, and they want it to be impossible to look A few weeks ago, we launched The ZIP Code Lottery — a data narrative showing how amputation rates in Los Angeles County track almost perfectly with poverty, not clinical severity. It struck a nerve. The response told us something important: people want to see the data, and they want it to be impossible to look A few weeks ago, we launched The ZIP Code Lottery — a data narrative showing how amputation rates in Los Angeles County track almost perfectly with poverty, not clinical severity. It struck a nerve. The response told us something important: people want to see the data, and they want it to be impossible to look - -

- Yet more data to support the contention that different matrices are deleteriously and similarly affected by this silent sinister syndrome Proportion and severity of periodontitis and correlation of periodontal inflamed surface area with glycemic status in type 2 diabetic neuropathy patients with and without diabetic foot Background The association between diabetic neuropathy with and without Yet more data to support the contention that different matrices are deleteriously and similarly affected by this silent sinister syndrome Proportion and severity of periodontitis and correlation of periodontal inflamed surface area with glycemic status in type 2 diabetic neuropathy patients with and without diabetic foot Background The association between diabetic neuropathy with and without Yet more data to support the contention that different matrices are deleteriously and similarly affected by this silent sinister syndrome Proportion and severity of periodontitis and correlation of periodontal inflamed surface area with glycemic status in type 2 diabetic neuropathy patients with and without diabetic foot Background The association between diabetic neuropathy with and without - -

- Inspired by much recent discussion as well as a blog post from 13 years ago, here is a manuscript just published. After further discussion with Prof. Ben Lipsky, he raises the interesting idea of calling some of these "infection in situ" just like cancer in situ. Inspired by much recent discussion as well as a blog post from 13 years ago, here is a manuscript just published. After further discussion with Prof. Ben Lipsky, he raises the interesting idea of calling some of these "infection in situ" just like cancer in situ. Inspired by much recent discussion as well as a blog post from 13 years ago, here is a manuscript just published. After further discussion with Prof. Ben Lipsky, he raises the interesting idea of calling some of these "infection in situ" just like cancer in situ. - -

- Two diabetic foot data engines published the same day on two continents. STEADY (US) is a 5,000-patient, AI-enabled real-world registry; DARE-DiaFoot (Italy) is a deep, multi-instrumental phenotyping protocol that quietly studies remission. One is the census, the other the core sample. Together with EURODIALE, the U.S. Wound Registry, and the National Diabetes Foot Care Audit, they sketch a blueprint for finally measuring what we manage. Two papers landed on the same day, on two continents, and if you squint they are the same paper wearing different lab coats. One is a census. The other is a core sample. Put them side by side and you get a working blueprint for the thing we keep saying we want and rarely build: Two diabetic foot data engines published the same day on two continents. STEADY (US) is a 5,000-patient, AI-enabled real-world registry; DARE-DiaFoot (Italy) is a deep, multi-instrumental phenotyping protocol that quietly studies remission. One is the census, the other the core sample. Together with EURODIALE, the U.S. Wound Registry, and the National Diabetes Foot Care Audit, they sketch a blueprint for finally measuring what we manage. - -

- A key Taiwanese nationwide study suggests that focusing on quality can improve outcomes. See for yourself: A nationwide cohort investigation on pay-for-performance and major adverse limb events in patients with diabetes A nationwide cohort investigation on pay-for-performance and major adverse limb events in patients with diabetes Highlights The nationwide population-base investigation unlinked vascular benefit of A key Taiwanese nationwide study suggests that focusing on quality can improve outcomes. See for yourself: A nationwide cohort investigation on pay-for-performance and major adverse limb events in patients with diabetes A nationwide cohort investigation on pay-for-performance and major adverse limb events in patients with diabetes Highlights The nationwide population-base investigation unlinked vascular benefit of A key Taiwanese nationwide study suggests that focusing on quality can improve outcomes. See for yourself: A nationwide cohort investigation on pay-for-performance and major adverse limb events in patients with diabetes A nationwide cohort investigation on pay-for-performance and major adverse limb events in patients with diabetes Highlights The nationwide population-base investigation unlinked vascular benefit of - -

- Our new paper in Burns and Trauma presents the most comprehensive review yet of spooky action at a distance therapies for diabetic limb preservation — from spinal cord stimulation and splenic ultrasound to remote ischemic conditioning and tibial transport. Five modalities, three mechanistic pathways, one shared destination: tissue repair at a distance. Einstein famously derided quantum entanglement as "spukhafte Fernwirkung" — spooky action at a distance. He could not accept that measuring one particle could instantaneously influence another, no matter how far apart. The idea offended his sense of how the universe should work. We borrowed that phrase — and that productive skepticism — for what may Our new paper in Burns and Trauma presents the most comprehensive review yet of spooky action at a distance therapies for diabetic limb preservation — from spinal cord stimulation and splenic ultrasound to remote ischemic conditioning and tibial transport. Five modalities, three mechanistic pathways, one shared destination: tissue repair at a distance. - -

- This just published in the American Journal of Managed Care (AJMC) detailing our collective experience treating high-risk patients with COVID19 A growing body of research, as well as first-hand accounts from clinicians on the ground, indicate that a significant percentage of patients with chronic wounds have delayed preventative and emergent wound care during the COVID-19 This just published in the American Journal of Managed Care (AJMC) detailing our collective experience treating high-risk patients with COVID19 A growing body of research, as well as first-hand accounts from clinicians on the ground, indicate that a significant percentage of patients with chronic wounds have delayed preventative and emergent wound care during the COVID-19 This just published in the American Journal of Managed Care (AJMC) detailing our collective experience treating high-risk patients with COVID19 A growing body of research, as well as first-hand accounts from clinicians on the ground, indicate that a significant percentage of patients with chronic wounds have delayed preventative and emergent wound care during the COVID-19 - -