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Deyasini Chakraborty

@deyasinic.bsky.social

Postdoc at the Novartis BR, Switzerland PhD, Thomä lab at the Friedrich Miescher Institute for Biomedical Research, Basel, Switzerland. Interested in chromatin biology.

Posts Replies Media

Deyasini Chakraborty @deyasinic.bsky.social · 07/08/2025

Excited that we got selected for the @cp-molcell.bsky.social cover for the latest issue released today! Congratulations @csandate.bsky.social!

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Deyasini Chakraborty @deyasinic.bsky.social · 04/08/2025

Excited to share that my first-author publication from my PhD on the interplay of p53 with cofactors on chromatin is now online in Molecular Cell @cp-molcell.bsky.social : www.cell.com/molecular-ce... Nucleosomes filter cofactor access to p53 - USP7 can bind whereas E6AP-E6 fails to form a complex.

cell.com

Nucleosomes specify co-factor access to p53

Chakraborty, Sandate, et al. report that chromatin-bound p53 interacts with deubiquitinating enzyme USP7 but not with the E3 ubiquitin ligase E6AP-E6, despite both co-factors being associated with the...

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Reposted by Deyasini Chakraborty

FMI science @fmiscience.bsky.social · 31/07/2025

Our cells pack DNA into tiny bundles that hide important parts. Researchers at the FMI and EPFL found this packing affects how the cancer-fighting protein p53 works, revealing new insights into cancer. www.fmi.ch/news-events/...

fmi.ch

How DNA packaging controls the “genome’s guardian”

Our cells tightly pack DNA into structures called nucleosomes, which protect DNA but also hide important sites. The key cancer-fighting protein p53 can still access these hidden sites, especially at n...

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Reposted by Deyasini Chakraborty

FMI science @fmiscience.bsky.social · 26/02/2025

Congratulations to Dr. Deyasini Chakraborty on defending her PhD thesis this week! 🥳🎓 Her research reveals how nucleosomes—structures of DNA wrapped around proteins—control the access of specific molecules to p53, a protein that helps regulate cell growth and prevent cancer.

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