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Dennis Wu

@denniswu02.bsky.social
10 followers 19 following 2 posts

G1 PhD Student @ Harvard MCO B.S in Biological Engineering @ Cornell 🧬🧪🔬 Prev undergrad researcher @ Feaga Lab 🧫👨‍🔬

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Reposted by Dennis Wu
Connor Tou @connorjtou.bsky.social · 11/03/2026
Today in @nature.com we introduce INSTALL, which bypasses mammalian DNA immune sensing to enable non-viral DNA integration with recombinases—a step toward safe, and mutation-agnostic genome editing. 🧬 🧵 (1/13) www.nature.com/articles/s41... @harvardmed.bsky.social @mgbresearch.bsky.social
nature.com
Immune evasive DNA donors and recombinases license kilobase-scale writing - Nature
INSTALL overcomes fundamental challenges for DNA delivery and integration methods by synergizing immune-stealth nucleic acids with recombinases to enable kilobase-scale integration strategies without ...
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Dennis Wu @denniswu02.bsky.social · 13/04/2025
Thrilled and proud to be part of this exciting discovery with the amazing Feaga Lab team! Grateful for everyone’s unwavering support throughout this journey! ❤️💙
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Reposted by Dennis Wu
Heather Feaga @heatherfeaga.bsky.social · 13/04/2025
Latest work from the lab - we identify a translation factor, YebC2, that reduces ribosome stalling in B. subtilis! Congrats to co-first authors: grad students Hye-Rim Hong & Cassidy Prince & undergrad Dennis Wu @denniswu02.bsky.social journals.plos.org/plosgenetics...
journals.plos.org
YebC2 resolves ribosome stalling and increases fitness of cells lacking EF-P and the ABCF ATPase YfmR
Author summary Polyproline motifs are essential structural features of many proteins but are difficult for the ribosome to synthesize. EF-P reduces ribosome pausing at polyproline motifs. Here, we sho...
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Reposted by Dennis Wu
Heather Feaga @heatherfeaga.bsky.social · 18/03/2025
We are so proud of Dennis Wu @denniswu02.bsky.social who is off to Harvard for grad school this fall! Keep your eyes peeled for a first-author paper from Dennis to be posted soon. Congrats Dennis! 🥳 ⚽️ 🦠
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