iiinova — where your digital self keeps evolving

Reposted by Delahny Deivendran

Hunter Shain @shainlab.bsky.social · 13/12/2025

Thank you to @bishaltandukar.bsky.social and Pedram Gerami (co-first authors) and the many others who contributed. @delahnydeivendran.bsky.social @sharmaharsh.bsky.social among many others not on Blue Sky

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Reposted by Delahny Deivendran

Hunter Shain @shainlab.bsky.social · 13/12/2025

Proud to share our new paper in Science Advances. We show that indoor tanning beds cause widespread mutational damage across the skin to increase melanoma risk, especially in body sites that rarely see sunlight. www.science.org/doi/10.1126/... #Melanoma #SkinCancer

science.org

Molecular effects of indoor tanning

The skin cells of tanning bed users have distinct mutational features as compared to people who only experience natural sunlight.

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Reposted by Delahny Deivendran

Hunter Shain @shainlab.bsky.social · 27/11/2025

Special thanks to @bishaltandukar.bsky.social @delahnydeivendran.bsky.social who led the study. Also thanks for funding from: the Human Tumor Atlas Network (HTAN), NCI, DOD, @melanomaresearch.bsky.social

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Reposted by Delahny Deivendran

Hunter Shain @shainlab.bsky.social · 27/11/2025

I am thrilled to share the latest manuscript from the Shain lab, describing the genetic changes that transform a keratinocyte into cutaneous squamous cell carcinoma (and everything in between). www.nature.com/articles/s41...

nature.com

Genetic evolution of keratinocytes to cutaneous squamous cell carcinoma

Nature Communications - The evolution of cutaneous squamous cell carcinoma (cSCC) remains poorly understood. Here, the authors employ multi-omics and multi-scale analyses to explore the genetic...

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