I’m delighted to announce that my first paper has been published in eLIFE!
In this paper, we explore how B cells alter their metabolism to fuel changes in cell growth and proliferation following stimulation with the toll-like receptor 4 (TLR4) ligand lipopolysaccharide.
elifesciences.org
Lipopolysaccharide stimulates dynamic changes in B cell metabolism to promote proliferation
B cell activation and antibody class switching requires coordinated metabolic rewiring, with essential roles for amino acid transport, cholesterol metabolism, and prenylation in driving proliferation ...