iiinova — where your digital self keeps evolving

Reposted by Daniel Reed

Kristian Pietras lab @kpietraslab.bsky.social · 09/12/2025

New paper alert 🚨 We are delighted to present our latest paper in @natcomms.nature.com through fabulous work from co-first authors Sebastian Braun and Paulina Bolivar! Big thanks to all expert collaborators for taking this long journey with us! Tweetorial in comments 🧵 www.nature.com/articles/s41...

nature.com

Pericytes orchestrate a tumor-restraining microenvironment in glioblastoma - Nature Communications

Improved understanding of the tumor ecosystem in glioblastoma is critical for developing new treatment strategies for the disease. Here, the authors identify pericytes as an active paracrine signaling...

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Reposted by Daniel Reed

Thomas R. Cox @trcox.matrixandmetastasis.com · 04/06/2025

New review paper written by Jess Chitty in the team just out in Trends in Cancer (@cp-trendscancer.bsky.social) (OpenAccess) The extracellular matrix in cancer: from understanding to targeting | → www.sciencedirect.com/science/arti... ← |

sciencedirect.com

The extracellular matrix in cancer: from understanding to targeting

Significant advances in matrix biology research have enhanced our understanding of individual matrix components and extracellular matrix (ECM) signall…

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Reposted by Daniel Reed

MBSANZ @mbsanz.bsky.social · 26/03/2025

Congratulations to @mbsanz.bsky.social MCR Paper of the Year 2024 Recipients, Brooke Pereira & Shona Ritchie, (co-led by @tcox.bsky.social ), for their latest work looking at the role of Nidogen-2 in pancreatic cancer published in Science Advances! www.science.org/doi/10.1126/...

science.org

Temporally resolved proteomics identifies nidogen-2 as a cotarget in pancreatic cancer that modulates fibrosis and therapy response

Temporal mass spectrometry proteomics, advanced microscopy, and in vivo modeling reveal nidogen-2 as a cotarget in PDAC.

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Daniel Reed @daniel-reed.bsky.social · 14/03/2025

Excited to kick off my Bluesky posting by sharing this work by the lab looking at the role of neuropeptideY in #pancreaticcancer metastasis. An amazing piece of work and so thrilled to see it finally out! @garvaninstitute.bsky.social www.science.org/doi/10.1126/...

science.org

Targeting the NPY/NPY1R signaling axis in mutant p53–dependent pancreatic cancer impairs metastasis

Targeting NPY1R reduces mutant p53–dependent pancreatic cancer metastasis.

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