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Daniel R. Cuesta-Aguirre

@dani96ra.bsky.social
74 followers 135 following 9 posts

PhD student in ancient populations genomics at the Universitat Autònoma de Barcelona

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Daniel R. Cuesta-Aguirre @dani96ra.bsky.social · 13/06/2026
"The genetic landscape of northeastern Iberian communities from the early to late Iron Age"
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Daniel R. Cuesta-Aguirre @dani96ra.bsky.social · 13/06/2026
Very happy to share our latest paper, published in @cp-iscience.bsky.social! 🎉 This work, led by @cmpereirasantos.bsky.social at the @uabbiociencies.bsky.social, was made possible by an amazing international team of collaborators. Thanks to everyone who contributed! doi.org/10.1016/j.is...
doi.org
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Reposted by Daniel R. Cuesta-Aguirre
Diari ARA @ara.cat · 26/03/2026
El juliol de 1348 hi va haver una matança terrible al call de Tàrrega. En coneixem l'abast per la documentació de la Cancelleria Reial, el relat de Josef ha-Kohen, L...
ara.cat
L'ADN revela la història i l'origen dels jueus assassinats a Tàrrega al segle XIV
La UAB fa el primer estudi genètic d'una comunitat jueva medieval a la península Ibèrica
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Daniel R. Cuesta-Aguirre @dani96ra.bsky.social · 06/02/2026
Happy to share our new open-access article on mitochondrial DNA heteroplasmy across different tissues in European populations 🧬 Read it here 👉 kwnsfk27.r.eu-west-1.awstrack.me/L0/https:%2F... Thanks to @GREAB_UAB @uabbiociencies.bsky.social @UABBarcelona #Mitochondrion
kwnsfk27.r.eu-west-1.awstrack.me
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Daniel R. Cuesta-Aguirre @dani96ra.bsky.social · 08/10/2025
Exciting news! Our new paper on ancient mtDNA from Iron Age NE Iberians is now published in #JournalOfArchaeologicalScience! 🧬 Huge thanks to co-authors & @GREAB_UAB, @uabbiociencies, and @UABBarcelona 🙏 Read it here 👉 doi.org/10.1016/j.ja...
doi.org
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Daniel R. Cuesta-Aguirre @dani96ra.bsky.social · 10/01/2025
5/ We hope this tool will help the aDNA community tackle challenges in analyzing degraded mtDNA samples and push the field forward! 👉 Read the full article here: doi.org/10.1111/1755... #AncientDNA #MolecularEcology #OpenScience
doi.org
A Post‐Mortem Molecular Damage Profile in the Ancient Human Mitochondrial DNA
Mitochondrial DNA (mtDNA) analysis is crucial for understanding human population structure and genetic diversity. However, post-mortem DNA damage poses challenges, that make analysis difficult. DNA p...
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Daniel R. Cuesta-Aguirre @dani96ra.bsky.social · 10/01/2025
4/ A huge thank you to my co-authors @crisamorjimenez.bsky.social, and @cmpereirasantos.bsky.social! 🙌
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Daniel R. Cuesta-Aguirre @dani96ra.bsky.social · 10/01/2025
3/ We compared the damage profile with mutational hotspots and heteroplasmic positions and found that 2,781 positions had not been previously reported in any of those profiles.
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Daniel R. Cuesta-Aguirre @dani96ra.bsky.social · 10/01/2025
2/ Using 427 non-UDG-treated ancient samples from NGS data, we created a comprehensive molecular damage profile for ancient mtDNA, identifying 2,933 damage hotspots across the human mitogenome (out of 11,735 evaluated positions).
Distribution of the 2933 hotspots identified in the present study. These hotspots exhibit a percentage exceeding 23.8% and collectively represent the top 25% of the positions with the highest values. The non-coding region is highlighted in red, while an orange line denotes the origin of replication. Region of the mitogenome with < 30 reads covering them in at least 75% (321 samples) of those analysed are shaded in blue to indicate their absence in our profile.
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Daniel R. Cuesta-Aguirre @dani96ra.bsky.social · 10/01/2025
1/ 🎉 Thrilled to announce our new paper, "A Post-Mortem Molecular Damage Profile in the Ancient Human Mitochondrial DNA," is now published in Molecular Ecology Resources! Check it out here: doi.org/10.1111/1755... #aDNA #genomics #mtDNA
doi.org
A Post‐Mortem Molecular Damage Profile in the Ancient Human Mitochondrial DNA
Mitochondrial DNA (mtDNA) analysis is crucial for understanding human population structure and genetic diversity. However, post-mortem DNA damage poses challenges, that make analysis difficult. DNA p...
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