Reposted by David Cagan
In @science.org for chemsky this week, Phil Baran’s group apply sulfonylhydrazides to stereoretentive alkyl-alkyl coupling
www.science.org/doi/10.1126/...
science.org
Stereoretentive radical-based alkyl-alkyl cross-coupling
The construction of stereogenic C(sp3)–C(sp3) bonds through cross-coupling remains a formidable challenge owing to competing β-hydride elimination and homocoupling as well as the poor inherent stereoc...
