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David Ochoa

@d0choa.bsky.social
334 followers 352 following 32 posts

Target discovery | Computational Biology | Human Disease Genetics | ML | Cloud computing - @opentargets.org - @ebi.embl.org

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David Ochoa @d0choa.bsky.social · 01/05/2026
🧬 New preprint: "The Human Pleiotropic Map of GWAS Associations and Therapeutic Implications" Why do some genetically supported drug targets succeed in the clinic while others fail? Across 100,526 GWAS, the same evidence flags constrained gene functions rarely safe to modulate.
The Human Pleiotropic Map of GWAS Associations and Therapeutic Implications
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David Ochoa @d0choa.bsky.social · 23/03/2026
The Open Targets Platform spring 🌼 release is out — and this one marks the beginning of something we've been building towards for a while.
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David Ochoa @d0choa.bsky.social · 18/06/2025
🚀 The Summer ☀️ @opentargets.org Platform release is here! If you thought the last update was big… just wait till you see what’s inside. A quick thread on the highlights 👇
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David Ochoa @d0choa.bsky.social · 28/03/2025
Big thanks to the community for the great feedback we are receiving on the spring @opentargets.org Platform release. There are many positive and new ideas for improving our scientific interpretation and products. Feedback is a critical aspect of an open project's lifecycle. Please keep it coming 🧬🖥️
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David Ochoa @d0choa.bsky.social · 17/12/2024
The merged product will bring the best of both worlds in a single web application, covering all journeys from identifying the likely causal signals to the prioritising factors relevant to target progression
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David Ochoa @d0choa.bsky.social · 17/12/2024
This update will power our current target identification coverage, as well as the mechanistic interpretation and biological context
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David Ochoa @d0choa.bsky.social · 17/12/2024
The update will include a refreshed post-GWAS analysis covering state-of-the-art data and methodologies, resulting on 2.5M GWAS and molQTL credible sets, colocalisation analysis and L2G predictions
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David Ochoa @d0choa.bsky.social · 17/12/2024
From next spring, the Open Targets Platform will incorporate the best of Open Targets Genetics into an integrated drug discovery platform 🧵
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David Ochoa @d0choa.bsky.social · 06/12/2024
In the upcoming NAR issue, we summarise the last 2 years of updates in the @opentargets.org Platform. One step at a time... academic.oup.com/nar/advance-...
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David Ochoa @d0choa.bsky.social · 28/11/2024
crispy morning in the genome campus…
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David Ochoa @d0choa.bsky.social · 21/11/2024
Moving day at @opentargets.org It always amazed me the UK ability to appreciate remarkable scientists. The new @ebi.embl.org building couldn’t be named after a more inspirational figure
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