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Clinical Trials Transformation Initiative (CTTI) @ctti-trials.bsky.social · 31/08/2026

As clinical development efficiency continues to evolve, understanding how expedited programs are used in practice is increasingly important. CTTI’s EEP booklet provides a foundation for considering lessons learned from these pathways. Explore the booklet: ow.ly/yBB650ZHiW6

Project title Enabling Expedited Pathways

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Clinical Trials Transformation Initiative (CTTI) @ctti-trials.bsky.social · 06/08/2026

Read now in the Journal of Clinical & Translational Science: #CTTI provides recommendations to support the broader use of disease progression modeling (DPM) in medical product development. 🔗https://ow.ly/kRU450Zx3ch

Title slide of a presentation on empowering clinical development using disease progression modeling by the Clinical Trials Transformation Initiative.

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Clinical Trials Transformation Initiative (CTTI) @ctti-trials.bsky.social · 14/07/2026

AI is already being used across drug and biological product development — but what will it take to ensure its use is responsible, transparent, and fit for purpose? 🔗 Explore key insights from the most recent FDA/CTTI Public Workshop: ow.ly/LHFb50Znow0

AI in Drug Development: Use Cases, Challenges, and Future Considerations

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Clinical Trials Transformation Initiative (CTTI) @ctti-trials.bsky.social · 17/06/2026

A new executive summary from CTTI’s Patient Summit highlights perspectives from #patients, caregivers, and advocates on key topics shaping clinical research. Read the summary and watch session recordings to learn more: ctti-clinicaltrials.org/by-topic/pat...

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CTTI Releases Executive Summary from Patient Summit - CTTI

On April 28, 2026, patients, caregivers, and advocates gathered for the CTTI Patient Summit to discuss perspectives on the use of AI in clinical trials, the reuse of patient data, and opportunities to...

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Clinical Trials Transformation Initiative (CTTI) @ctti-trials.bsky.social · 26/05/2026

Join Dr. Leonor Corsino and CTTI's Sabrena Mervin-Blake today at the Duke CTSI Trustworthy Translation Symposium for the workshop “Building Trust and Partnerships in Clinical Research.” 📅 May 26, 2026 🕑 2:15–3:00 PM 📍 Duke Trent Semans Conference Center, Room 3025

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Clinical Trials Transformation Initiative (CTTI) @ctti-trials.bsky.social · 12/03/2026

Patients, caregivers, and patient advocates: Join the CTTI Patient Summit on April 28 (1:00–3:00 p.m. EDT) to share perspectives on privacy boundaries, participant data access, and AI in clinical trials. 🔗 Register now: duke.zoom.us/meeting/regi...

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Clinical Trials Transformation Initiative (CTTI) @ctti-trials.bsky.social · 11/12/2025

What should we measure to advance clinical trials? Ed Ramos, former CTTI Executive Committee member, expounds on how CTTI is measuring data reuse and why it matters in reducing participant burden. Watch the video interview now: bit.ly/MTTMetricsFr....

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Metrics for Measuring Trials Transformation: An Interview with Ed Ramos

This is "Metrics for Measuring Trials Transformation: An Interview with Ed Ramos" by CTTI on Vimeo, the home for high quality videos and the people who…

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Clinical Trials Transformation Initiative (CTTI) @ctti-trials.bsky.social · 06/10/2025

TOMORROW: Join #FDA & #CTTI for a free hybrid workshop to discuss real-world #AI applications & future opportunities in drug and biological product development. Register now: bit.ly/3JuOhZQ

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Clinical Trials Transformation Initiative (CTTI) @ctti-trials.bsky.social · 03/10/2025

Just a few days left to register for #FDA & #CTTI’s 10/7 hybrid public workshop. Join us to explore innovative, responsible & impactful uses of #AI in drug & biological product development. bit.ly/3JuOhZQ

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Clinical Trials Transformation Initiative (CTTI) @ctti-trials.bsky.social · 03/10/2025

Next week at #FierceBiotech Week 2025, CTTI’s Lindsay Kehoe will share bold strategies to overcome barriers in clinical research and chart a path toward a more inclusive, efficient, and patient-centered trials ecosystem. 📅 Oct 7 | 9:00 AM | Boston

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Clinical Trials Transformation Initiative (CTTI) @ctti-trials.bsky.social · 30/09/2025

Final days to register: On 10/7, #FDA & #CTTI will host a hybrid public workshop on how real-world AI use is advancing transparency, quality, safety, and efficacy in product development. bit.ly/3JuOhZQ

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Clinical Trials Transformation Initiative (CTTI) @ctti-trials.bsky.social · 25/09/2025

Explore cross-disciplinary collaborations & practical steps for using #AI responsibly in medical product development. Join #FDA & #CTTI’s hybrid workshop on 10/7: bit.ly/3JuOhZQ

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Clinical Trials Transformation Initiative (CTTI) @ctti-trials.bsky.social · 09/09/2025

Join #FDA & #CTTI on 10/7 for a free hybrid workshop exploring how #AI is reshaping drug & biological development. Hear from experts on real-world breakthroughs, data challenges, and what’s next. Register now: bit.ly/3JuOhZQ

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Clinical Trials Transformation Initiative (CTTI) @ctti-trials.bsky.social · 04/09/2025

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Clinical Trials Transformation Initiative (CTTI) @ctti-trials.bsky.social · 25/08/2025

FDA & #CTTI will host a hybrid public workshop on 10/7 to explore the evolving role of #AI in drug & biological product development. Registration is now open: bit.ly/3JuOhZQ

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Clinical Trials Transformation Initiative (CTTI) @ctti-trials.bsky.social · 06/08/2025

🎥 Why Now, Why Us: Answering the Call to Transform #ClinicalTrials What inspired leaders from across the research ecosystem to attend the #StateOfClinicalTrials? Hear their “why” in this powerful new video from #CTTI. ▶️ Watch now: bit.ly/3HlK1uU

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Why Now, Why Us: Answering the Call to Transform Clinical Trials

May 22, 2025

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Clinical Trials Transformation Initiative (CTTI) @ctti-trials.bsky.social · 23/07/2025

Today #CTTI honors the life of Phil Green, who turned his #ALS diagnosis into a mission to improve #clinicaltrials for all. His leadership, empathy & work with CTTI helped drive more patient-centered, accessible research. His legacy lives on. 🧡 bit.ly/green-phil

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Clinical Trials Transformation Initiative (CTTI) @ctti-trials.bsky.social · 17/07/2025

How can disease progression modeling support better trial design and decision making? Watch #CTTI’s webinar and explore the recommendations and considerations framework for practical guidance. #DPM bit.ly/460j361

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Clinical Trials Transformation Initiative (CTTI) @ctti-trials.bsky.social · 15/07/2025

The recording of #CTTI’s webinar on disease progression modeling is now available. Hear expert insights and explore the recommendations & considerations framework to guide thoughtful use of #DPM in clinical development. bit.ly/460j361

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Clinical Trials Transformation Initiative (CTTI) @ctti-trials.bsky.social · 01/07/2025

🎬 Missed the inaugural State of Clinical Trials meeting? Watch the highlight video to see how 150 leaders are shaping the future of research—together. From patient-centricity to policy shifts, the momentum is real. bit.ly/SOCThighlights

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Highlights from CTTI's Inaugural State of Clinical Trials Meeting

May 22, 2025

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Clinical Trials Transformation Initiative (CTTI) @ctti-trials.bsky.social · 25/06/2025

#CTTI’s Watchtower project is developing tools to assess and enhance U.S. #clinicaltrial site capacity—supporting a faster, more unified research response when the next public health emergency strikes. Learn more: bit.ly/44kvet1

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Clinical Trials Transformation Initiative (CTTI) @ctti-trials.bsky.social · 23/06/2025

From expert meetings to reviewing infrastructure mapping projects, #CTTI’s Watchtower project is gathering the data needed to improve trial site readiness nationwide. Learn how: bit.ly/44kvet1

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Clinical Trials Transformation Initiative (CTTI) @ctti-trials.bsky.social · 23/06/2025

How do we define trustworthy pharma in 2025? Tomorrow #CTTI’s Morgan Hanger will moderate a small group at the 2025 Ethics & Pharma Roundtable—driving bold ideas on metrics for transparency, trust & patient-first R&D. Don’t miss it!

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Clinical Trials Transformation Initiative (CTTI) @ctti-trials.bsky.social · 20/06/2025

#CTTI’s Watchtower project is creating a framework to evaluate U.S. #clinicaltrial site readiness— helping to support faster, more coordinated research during future public health emergencies. Learn more: bit.ly/44kvet1

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Clinical Trials Transformation Initiative (CTTI) @ctti-trials.bsky.social · 17/06/2025

🚨 Join us on 6/24 at the 2025 Roundtable on Ethics, Trust + Patient Centricity in Pharma, hosted by Bioethics International, EY, Yale, & Scientific American! #CTTI's Morgan Hanger speaks on transparency & ethics in #clinicaltrials.

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Clinical Trials Transformation Initiative (CTTI) @ctti-trials.bsky.social · 17/06/2025

#CTTI’s Watchtower project is assessing #clinicaltrial site readiness in the U.S. to better respond to public health emergencies. Learn how we’re working to rapidly expand research capacity in times of urgent need: bit.ly/44kvet1

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Clinical Trials Transformation Initiative (CTTI) @ctti-trials.bsky.social · 17/06/2025

#Decentralized #clinicaltrials. Embedded research. Adjusted settings. What do they really mean for data quality? Find out tomorrow at #DIA2025 with #CTTI’s Lindsay Kehoe + experts from FDA, NIH & Florence Healthcare.

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Clinical Trials Transformation Initiative (CTTI) @ctti-trials.bsky.social · 16/06/2025

Still hitting roadblocks with #QbD and Risk-Based Monitoring? Hear fresh case studies and solutions from CTTI’s Morgan Hanger & experts at #DIA2025 this Wednesday!

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Clinical Trials Transformation Initiative (CTTI) @ctti-trials.bsky.social · 13/06/2025

Can flexible trials still deliver high-quality data? 🤔 Join us at #DIA2025 on June 18 for, “Do Flexible Trial Approaches Impede Data Quality?” #CTTI’s Lindsay Kehoe leads the convo with @US_FDA, @NIH & @FlorenceHCare. Let’s bust some myths. 💥

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Clinical Trials Transformation Initiative (CTTI) @ctti-trials.bsky.social · 12/06/2025

Heading to #DIA2025? Join #CTTI’s Morgan Hanger on 6/18 for “Building Upon Quality by Design and Risk-Based Monitoring Implementation Momentum.” New case studies. Real solutions. Practical tools to drive adoption + impact. #clinicaltrials #QbD

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Clinical Trials Transformation Initiative (CTTI) @ctti-trials.bsky.social · 12/06/2025

Today is the last day to complete the survey for #CTTI’s workshop on #AI in Drug and Biological Product Development. Your input will help shape this year’s agenda: bit.ly/4jCWiIu

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Clinical Trials Transformation Initiative (CTTI) @ctti-trials.bsky.social · 10/06/2025

DYK that disease progression modeling (DPM) can improve trial efficiency, clarify uncertainty & support precision medicine? Join #CTTI on 7/8 @ noon EDT for a free webinar launching new recs on using DPM in medical product development. bit.ly/3ZoQFGy

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Clinical Trials Transformation Initiative (CTTI) @ctti-trials.bsky.social · 10/06/2025

There’s still time to share your input for #CTTI’s workshop on #AI in Drug and Biological Product Development. Take the short survey to help guide the discussion: bit.ly/4jCWiIu

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Clinical Trials Transformation Initiative (CTTI) @ctti-trials.bsky.social · 09/06/2025

150+ leaders. 1 big goal: transform #clinicaltrials. #CTTI’s inaugural #StateOfClinicalTrials meeting tackled the toughest barriers to change—and sparked bold, actionable ideas. 🔗 Dive into the recap: Inside the State of Clinical Trials bit.ly/SOCT

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Clinical Trials Transformation Initiative (CTTI) @ctti-trials.bsky.social · 06/06/2025

#CTTI is currently planning a future hybrid public workshop on #AI in Drug and Biological Product Development. Help shape the agenda by completing a brief survey: bit.ly/4jCWiIu

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Clinical Trials Transformation Initiative (CTTI) @ctti-trials.bsky.social · 20/05/2025

Today #CTTI celebrates #ClinicalTrialsDay by recognizing participants, researchers & healthcare heroes advancing medical progress every day. We're proud to work toward faster, more inclusive & patient-centered trials. Let’s keep transforming research—together. #CTD2025 #TT2030

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Clinical Trials Transformation Initiative (CTTI) @ctti-trials.bsky.social · 19/05/2025

In 2023, over 7,600 U.S. interventional trials were launched—but most remain small, regardless of sponsor. New #SCT2025 research—featuring contributions from #CTTI’s Sara Bristol Calvert—breaks down trial size, focus, and funder differences. Don’t miss it tomorrow!

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Clinical Trials Transformation Initiative (CTTI) @ctti-trials.bsky.social · 16/05/2025

How do funders shape #clinicalresearch? #CTTI’s Sara Bristol Calvert contributed to new analysis revealing that most U.S. trials are small – and funder type drives the use of behavioral vs drug interventions. Check it out at #SCT2025!

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Clinical Trials Transformation Initiative (CTTI) @ctti-trials.bsky.social · 14/05/2025

Heading to #SCT2025? Don’t miss new research on U.S. #clinicaltrials launched in 2023, revealing how trial size and focus vary by funding source. #CTTI’s Sara Bristol Calvert contributed to this important work. @sarabc35.bsky.social

ClinicalTrials.gov presentation at Society for Clinical Trials Annual Meeting

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