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Emily Rundlet

@cryoemily.bsky.social

53 followers 89 following 0 posts

JCC fellow and Postdoc in the McLellan Lab at UT Austin

Posts Replies Media

Reposted by Emily Rundlet

David Bartel's Lab @bartellab.bsky.social · 07/11/2025

Check out the latest work from our lab, led by Daniel Lin and Lara Elcavage: www.biorxiv.org/content/10.1... (1/3)

biorxiv.org

mRNA 3′ UTRs direct microRNA degradation to participate in imprinted gene networks and regulate growth

MicroRNAs direct downregulation of target mRNAs. Sometimes, however, this regulatory paradigm inverts, and a target RNA triggers the degradation of a microRNA. This target-directed microRNA degradatio...

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Reposted by Emily Rundlet

Jason McLellan @mclellanlab.bsky.social · 19/08/2025

Our preprint, in collaboration with Rino Rappuoli & Emanuele Andreano, is out! Co-led by colleagues at TLS, my grad student Ling Zhou @lingzhou.bsky.social, and postdoc Emily Rundlet @cryoemily.bsky.social, we identified OPG153 as a poxvirus bnAb target via B cell isolation & AlphaFold3 prediction.

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Reposted by Emily Rundlet

Jason McLellan @mclellanlab.bsky.social · 18/06/2025

Our latest preprint is now available doi.org/10.1101/2025...! Led by my postdoc, Luqiang Guo @luqiang.bsky.social, we determined a ~2.4 A resolution structure of the hantavirus glycoprotein tetramer on the surface of VLPs. Also determined structures of dimers of tetramers and Fab-bound tetramers.

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Reposted by Emily Rundlet

Zunlong Ke @zunlongke.bsky.social · 29/11/2024

A fun journey of full-length EGFR with Dan Leahy and @edwardmarcotte.bsky.social at UT Austin @utaustin.bsky.social. See below: Structure and organization of full-length Epidermal Growth Factor Receptor in extracellular vesicles by cryo-electron tomography www.biorxiv.org/content/10.1...

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Reposted by Emily Rundlet

Jason McLellan @mclellanlab.bsky.social · 20/05/2025

Check out our latest study, led by grad student Ryan McCool @rmccool.bsky.social‬, in collaboration with Vaccine Company. We were able to stabilize EBV gB in the prefusion conformation, determine its cryo-EM structure to 3.1 A, and assess its immunogenicity in mice. www.biorxiv.org/cgi/content/...

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