A novel metaheuristic optimization algorithm, namely the Farthest better or Nearest worse Optimizer (FNO) algorithm, is proposed in this paper. The idea behind the FNO algorithm is derived from the qu...

Single-cell RNA-seq data from clinical samples often suffer from batch effects, but data sharing is limited due to genomic privacy concerns. We present FedscGen, a privacy-preserving communication-eff...

In this Resource, the authors present FedProt, a tool that enables privacy-preserving, federated differential protein abundance analysis across multiple institutions. Its results match the results of ...

Abstract. Despite the significant progress in accuracy and reliability in mass spectrometry technology, as well as the development of strategies based on i

Prognostic models in medicine have garnered significant attention, with established guidelines governing their development. However, there remains a lack of clarity regarding the appropriate circumsta...

Abstract. Defective interfering particles (DIPs) are viral deletion mutants that hamper virus replication and are, thus, potent novel antiviral agents. To

AbstractMotivation. Transcription factors (TFs) are DNA-binding proteins that regulate gene expression. Traditional methods predict a protein as a TF if th

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Nature Biotechnology - A platform for the biomedical application of large language models