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Cortical Bionics Research Group

@corticalbionics.bsky.social
256 followers 32 following 19 posts

Collaboration between University of Pittsburgh, University of Chicago and Northwestern researchers to develop a brain-computer interface for prosthetic arm and hand control with sensory feedback.

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Reposted by Cortical Bionics Research Group
Giacomo Valle @giacomovalle.bsky.social · 04/09/2026
🎉I’m grateful that my project #BionicDexterity has been awarded a 2.5M € ERC Starting Grant! 🧠🦾 Over 5 years, we’ll investigate at #Chalmers how to create a multimodal #iBCI capable of restoring dexterity after paralysis @erc.europa.eu
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Science Magazine @science.org · 20/07/2026
Intracortical microstimulation electrodes are safe and produce consistent sensations for as long as a decade in patients with spinal cord injury, supporting their utility in #BrainComputer interface interventions. Learn more in #ScienceTranslationalMedicine: scim.ag/4fmHddQ
scim.ag
Long-term safety and efficacy of intracortical microstimulation in humans
Intracortical microstimulation in humans is safe and efficacious for up to 10 years.
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Giacomo Valle @giacomovalle.bsky.social · 02/06/2026
After more than 5 decades of parallel development, #corticalstimulation for artificial #vision & artificial #touch is beginning to converge rdcu.be/flRzh Our new @natrevbioeng.nature.com review brings together shared principles and modality-specific strategies across both fields
rdcu.be
Restoring vision and touch with cortical microstimulation
Nature Reviews Bioengineering - Cortical sensory prostheses aim to restore vision and touch by stimulating primary visual and somatosensory cortices. This Review examines shared challenges and...
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Giacomo Valle @giacomovalle.bsky.social · 13/05/2026
NEW PREPRINT OUT! Happy to share that our #preprint on how the human #brain encodes #touch: biorxiv.org/content/10.6... We investigate how touch is encoded in the human #somatosensory and #motor cortices recorded via #microelectrode arrays across different tactile conditions
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Cortical Bionics Research Group @corticalbionics.bsky.social · 09/03/2026
Once we identified error in real-time, we automatically slowed the cursor movement. This step improved trial accuracy and speed, and lowered the perceived difficulty of the task. A quick, accurate and easy-to-use device will be a boon for people with motor disabilities who benefit from BCI.
Comparison of movement trajectories without error recognition (blue) and with it (yellow). The yellow trajectories are much more direct.
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Cortical Bionics Research Group @corticalbionics.bsky.social · 09/03/2026
We first identified times of erroneous movements during unassisted cursor control (red). We then added the pre-error window (yellow, 0.2 seconds before error begins). We found that we could reliably classify these time windows from electrodes in motor cortex of 4 study participants.
Example BCI-controlled cursor trajectory, with erroneous movements in red, and pre-error movements in yellow.
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Cortical Bionics Research Group @corticalbionics.bsky.social · 09/03/2026
Our latest preprint uses the brain's own recognition, and prediction, of movement errors to improve Brain-Computer Interface control. This work, led by @camillegontier.bsky.social and @jenpitt.bsky.social, sets the stage for more accurate and easy-to-use BCIs. www.biorxiv.org/content/10.6...
biorxiv.org
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John Downey @johndowney.bsky.social · 02/03/2026
We are excited to share the preprint for a new project, "Finding the groove in neural space". www.medrxiv.org/content/10.6... 1/4
medrxiv.org
Finding the groove in neural space
The neural signature of rhythm and tempo remains difficult to study in both humans and non-human primates. Here we recorded from the motor cortex of human participants implanted with intracortical mic...
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Reposted by Cortical Bionics Research Group
BCI Society @bcisociety.bsky.social · 21/08/2025
Huge thanks to our generous sponsors — Blackrock Neurotech, Cleveland FES Center, Brain Products / Brain Vision, and CorTec — for supporting the BCI Society’s SfN Social 2025! Your partnership makes this special event possible. Learn more: bcisociety.org/bci-social-a... #BCISocial #SfN2025
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BCI Society @bcisociety.bsky.social · 19/08/2025
The BCI Society is excited to introduce a new, discounted membership for BCI users and their family members or caregivers. See bcisociety.org/membership/ for details.
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Cortical Bionics Research Group @corticalbionics.bsky.social · 13/08/2025
This work was led by Charles Greenspon, Taylor Hobbs and Rob Gaunt with help from many other CBRG researchers including, on Bluesky: @jenpitt.bsky.social @johndowney.bsky.social @giacomovalle.bsky.social @jeffweiss.bsky.social @joelye.bsky.social
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Cortical Bionics Research Group @corticalbionics.bsky.social · 13/08/2025
We saw zero serious adverse events. Moreover, delivering millions of pulses had no effect on electrode health or changes in neural excitability. This is the first long term study of ICMS in humans and shows that it can be safe to use for clinical devices.
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Cortical Bionics Research Group @corticalbionics.bsky.social · 13/08/2025
The most recent CBRG preprint on intracortical microstimulation is now available! Over 24 combined years across 5 participants, we delivered 168 million!!! pulses of stimulation and recorded everything that happened. www.medrxiv.org/content/10.1...
medrxiv.org
Intracortical microstimulation in humans: a decade of safety and efficacy
Background Intracortical microstimulation (ICMS) of somatosensory cortex can restore a sense of touch to people with spinal cord injury (SCI). In this early-feasibility clinical trial, we evaluate the...
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Cortical Bionics Research Group @corticalbionics.bsky.social · 09/06/2025
We had a great time at the @bcisociety.bsky.social meeting in Banff, Canada. We gathered almost all (@hunterschone.bsky.social?) the CBRG attendees (current and former) for the official photo. @jenpitt.bsky.social @giacomovalle.bsky.social @johndowney.bsky.social @miskarous.bsky.social
The current and former CBRG members who attended the BCI Society Meeting, gathered together in front of a spectacular mountain view.
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Cortical Bionics Research Group @corticalbionics.bsky.social · 07/05/2025
These results are an important step towards invoking accurate sensation of touch on a person’s paralyzed hand and creating an artificial limb that seamlessly integrates into a person’s unique sensory world. Great work by the whole CBRG team, and a big thank you to our dedicated participants.
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Cortical Bionics Research Group @corticalbionics.bsky.social · 07/05/2025
The sensations were then replayed, without seeing the object, and they could still identify the object, albeit with mistakes. They often mistakenly selected objects with similar properties (cats and towels are both soft), suggesting that the sensations contained intuitive object features.
The screen presented during the object identification task. Participants could "touch" the blank box, then identify which object it is from the silhouettes presented at the bottom.
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Cortical Bionics Research Group @corticalbionics.bsky.social · 07/05/2025
Participants saw an object and edited parameters of their artificially created sense of touch to match. Participants described, e.g., the warm fur of a purring cat, or the smooth rigid surface of a door key.
An image of the test setup. When participants could move the red dots in 2 2D planes to change 4 stimulation parameters to which they were blinded. Then they, or an assistant, could touch the digital object and trigger stimulation with the selected parameters on the electrodes to feel if it matched their expectations of the object.
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Cortical Bionics Research Group @corticalbionics.bsky.social · 07/05/2025
Here’s our latest publication, from Ceci Verbaarschot and colleagues. In this study, participants controlled their own implanted BCI brain stimulation patterns to create customized sensations. www.nature.com/articles/s41...
nature.com
Conveying tactile object characteristics through customized intracortical microstimulation of the human somatosensory cortex - Nature Communications
In this study, three individuals with tetraplegia designed vivid, reliable and object-appropriate sensations with a variety of tactile characteristics using self-selected stimulus parameters that stim...
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Giacomo Valle @giacomovalle.bsky.social · 24/01/2025
Our work featured in: @thetimes.com by Tom Whipple www.thetimes.com/uk/science/a...
thetimes.com
The paralysed people moving robotic arms with their minds
A Swedish study aims to restore their ability to feel and handle objects — and gain independence
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Cortical Bionics Research Group @corticalbionics.bsky.social · 17/01/2025
Check out @giacomovalle.bsky.social's summary of our new paper showing the details that we can convey to BCI users through spatio-temporally patterned stimulation in somatosensory cortex. This is a great step towards restoring natural sensation from future prosthetic hands.
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Giacomo Valle @giacomovalle.bsky.social · 10/01/2025
Our paper examining the #ethical and #technical requirements in clinical trials for implantable neural prostheses is out in #LancetDigitalHealth today. www.thelancet.com/journals/lan... Neural Bionics Lab Chalmers University of Technology @corticalbionics.bsky.social #neuroprosthetics
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John Downey @johndowney.bsky.social · 30/12/2024
Our new publication in Human Brain Mapping is a roadmap to implanting stimulation electrodes to evoke tactile sensations on the fingers of Brain-Computer Interface (BCI) users. We share the plan and results for 5 study participants across a decade at 2 sites. onlinelibrary.wiley.com/doi/10.1002/...
Progression of implant plan from placement map, to surgical image, to stimulation results.
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Cortical Bionics Research Group @corticalbionics.bsky.social · 19/12/2024
Marc Schieber has published his insightful thoughts on the below paper and where it fits in the broader efforts towards dexterous neuroprosthetic hands in Nature BME: www.nature.com/articles/s41...
nature.com
Stimulating localizable sensations - Nature Biomedical Engineering
Overlapping projected fields from multiple intracortical electrodes produce sensations on the hand that are more easily localizable, as shown in three participants with cervical spinal cord injury.
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Cortical Bionics Research Group @corticalbionics.bsky.social · 09/12/2024
This was a big team effort by the labs, and especially the study participants, across three universities (UChicago, Pitt, and a guest appearance from Case Western). These results a big step forward as we continue to improve the capabilities of ICMS to restore tactile sensations post-injury.
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Cortical Bionics Research Group @corticalbionics.bsky.social · 09/12/2024
These interactions allowed us to improve the ability of participants to both locate which finger an object was contacting as well as how much force was being applied to it.
Figure showing how the above findings improve the utility of sensors on a robotic hand by increasing sensation clarity on the fingers and enabling detection of object softness when grasping.
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Cortical Bionics Research Group @corticalbionics.bsky.social · 09/12/2024
Given that some electrodes overlapped, we examined the interaction and found that they generally summed together making more intense sensations.
Figure showing that stimulating two electrodes at once evokes a sensation that approximates the sum of the sensations when each electrode is stimulated independently.
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Cortical Bionics Research Group @corticalbionics.bsky.social · 09/12/2024
We compared the percept locations with receptive field locations (area on the hand that when touched evokes neural activity near an electrode) when possible and found that the vast majority of percepts fell within the matched receptive fields.
Figure showing that electrodes that record activity when a part of the hand is touched, evoke a sensation in the same area of the hand when stimulated.
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Cortical Bionics Research Group @corticalbionics.bsky.social · 09/12/2024
We first looked to see if ICMS-evoked percepts (a sensation caused by stimulation on an electrode) were in consistent locations across the duration of the study and found that across 2-7 years they were.
A figure from the linked paper, showing where participants feel sensations during electrical stimulation, and that the locations are stable over time.
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Cortical Bionics Research Group @corticalbionics.bsky.social · 09/12/2024
Our group has a new paper out now in Nature BME, led by Charles Greenspon. It covers a number of updates on how we can restore tactile sensation from the hand using intracortical microstimulation (ICMS). www.nature.com/articles/s41...
nature.com
Evoking stable and precise tactile sensations via multi-electrode intracortical microstimulation of the somatosensory cortex - Nature Biomedical Engineering
An analysis of the localization and intensity of intracortical microstimulation in three participants with cervical spinal cord injury shows that overlapping projected fields from multiple electrodes ...
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John Downey @johndowney.bsky.social · 12/11/2024
There's a great new story out today in Nature about the state of sensory neuroprosthetic research. It features one of our participants from the University of Chicago and glimpses of exciting research from around the world. www.nature.com/articles/d41...
nature.com
The quest to build bionic limbs that feel like the real thing
Through brain implants, neural interfaces and skin grafts, researchers are starting to restore sensation for paralysed or amputated limbs.
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John Downey @johndowney.bsky.social · 29/02/2024
We are seeking a postdoc to work in sensorimotor neuroscience with brain-computer interfaces (BCI). The projects will focus on dexterous hand control through neural recordings and restoration of sensation to neural stimulation.
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John Downey @johndowney.bsky.social · 10/11/2023
Check out our first paper, out today, from the Cortical Bionics Research Group's (@corticalbionics.bsky.social) multisite brain-computer interface (BCI) clinical trial for people with upper-limb paralysis at UChicago and @pitt.bsky.social . 1/9 www.nature.com/articles/s41...
nature.com
Microstimulation of human somatosensory cortex evokes task-dependent, spatially patterned responses ...
Here the authors record the responses evoked in the hand and arm representations of M1 during intracortical microstimulation in the hand representation of S1, and show somatotopically organized connec...
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