Despite the global burden of hepatitis E virus (HEV) infection, host-virus interactions underlying HEV pathogenesis and progression to chronicity remain incompletely understood. This study aimed to ch...

In Rio de Janeiro treffen sich von heute an Tausende Menschen zur internationalen Aids-Konferenz - dem größten und wichtigsten Forum zum Thema HIV und Aids. Wie steht es um die Forschung? Ein Überblic...

The Paslahepevirus balayani hepatitis E virus (HEV) and the distantly related Rocahepevirus ratti rat HEV pose a risk for zoonotic transmission to humans. Despite the broad host range, including it...

Dennis Otieno likes to improve the understanding of yellow fever virus biology and vaccine development.

Bereits in den ersten Wochen einer Hepatitis-E-Infektion entstehen Veränderungen im Erbgut des Virus. Bochumer Forschende haben die Dynamik dieser Phase untersucht und charakteristische Mutationsmuste...

The hepatitis E virus is the leading cause of acute viral hepatitis globally. While studies of chronic infections have shown that HEV can evolve and adapt in ways that influence antiviral treatment responses, little is known about how the virus changes during the early, acute phase of infection. By analyzing viral populations in asymptomatic blood donors, this study demonstrates that HEV undergoes dynamic evolutionary changes even during short, self-limiting infections. Although overall viral diversity remains restricted, selective pressures still drive the emergence of new variants, including some with impaired replication capacity. These findings provide important mechanistic insight into early intra-host viral evolution and the conditions that allow defective variants to transiently persist. This work establishes a foundation for future studies linking viral genetic variation to disease progression, clinical outcomes, and treatment responsiveness.

Eine Impfung gegen Humane Papillomviren (HPV) kann Krebserkrankungen und Todesfälle effektiv verhindern - das zeigt eine aktuelle, englische Studie. Doch in Deutschland wird sie noch zu wenig genutzt....

Days Hours Minutes Seconds Program Registration Abstracts Organizing Committee Social Events Welcome to HCV-Flavi 2026 We warmly invite you to join the 32nd International Symposium on Hepatitis C Viru...

Effective antiviral drugs remain unavailable for many clinically relevant pathogens, including the hepatitis E virus (HEV). This study aimed to evalua…

Auf einem Kreuzfahrtschiff haben sich mehrere Personen mit dem Virus angesteckt. Handelsübliche Desinfektionsmittel inaktivieren es zuverlässig.

Die Frankfurter Virologin Sandra Ciesek plädiert für Apotheken als niedrigschwellige Zugangsorte für das Impfen. Im Prinzip zähle dabei...

The Max Delbrück Center for Molecular Medicine in the Helmholtz Association aims to transform tomorrow’s medicine through our discoveries of today. At locations in Berlin-Buch, Berlin-Mitte, Heidelber...

Every year, there are about one billion cases of influenza globally, causing hundreds of thousands of deaths.

Die traditionelle Auszeichnung der Studierenden hat dieses Mal im Stadtarchiv den passenden sportlichen Rahmen bekommen.

Ein neuer Influenza-Subtyp breitet sich derzeit in Europa aus. Die sogenannte Subklade K unterscheidet sich deutlich von den Viren, gegen die sich die aktuellen Grippe-Impfstoffe richten. Von F. Bäume...

Background and Aims The second Hepatitis E Symposium was held as an integral part of the International DFG/DZIF Joint Meeting on Viral Infections of the Liver and the Heart in Berlin. The symposium .....

Days Hours Minutes Seconds Welcome to HCV-Flavi 2026 We warmly invite you to join the 32nd International Symposium on Hepatitis C Virus, Flaviviruses and Related Viruses (HCV-Flavi 2026) in Copenhagen...

Author summary Hepatitis E virus (HEV) is an important yet often underestimated pathogen. Depending on the genotype, HEV infections can progress to chronicity, but the underlying mechanisms remain poo...