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Children's Medical Research Institute

@cmri.bsky.social
102 followers 28 following 133 posts

Children's Medical Research Institute (CMRI) is an independent organisation committed to the treatment or prevention of birth defects and childhood disease. Visit our website to learn more: www.cmrijeansforgenes.org.au

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Children's Medical Research Institute @cmri.bsky.social · 02/10/2026
New research published by A/Prof Pengyi Yang and his team in Cell Press Cell Systems introduces a computational framework for helping researchers assess the accuracy of stem-cell-derived models known as blastoids. doi.org/10.1016/j.cels.2026.101738
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Children's Medical Research Institute @cmri.bsky.social · 22/09/2026
CMRI’s Dr Mark Graham, Dr Nader Aryamanesh and Dr Lee Marshall contributed specialist proteomics and bioinformatics expertise to a collaborative study exploring how children with #cysticfibrosis respond to triple therapy. Read the research: doi.org/10.1016/j.isci.2026.117321
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Children's Medical Research Institute @cmri.bsky.social · 16/09/2026
A simple lab change could help speed up the search for treatments for inherited blindness. CMRI researchers found that growing lab-based retinal models in a different culture solution, BrainPhys, could make gene therapy testing faster and cheaper. Read the research: ow.ly/nUnh50ZMpRL
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Children's Medical Research Institute @cmri.bsky.social · 11/09/2026
A child's growing liver has long worked against #genetherapy. #CMRI researchers found a way to repair the faulty gene at its source instead of adding a copy that gets diluted over time. Early results are promising. Full publication here: doi.org/10.1016/j.ymthe.2026.06.044
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Children's Medical Research Institute @cmri.bsky.social · 09/09/2026
Today is MRI Giving Day! CMRI is proud to be part of a national community coming together to support medical research and help create a healthier future. Every gift helps transform what’s possible for children and families. Make your matched gift today: ow.ly/Rg3b50ZL59I
Medical Research Giving Day is live with a scientist using a microscope and a call to donate now.Medical Research Giving Day unites 30+ institutes and donors to fund life-saving breakthroughs on September 9.
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Children's Medical Research Institute @cmri.bsky.social · 26/08/2026
UPDATE: Early Bird registration deadline has now been extended to Friday 25 September.
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Children's Medical Research Institute @cmri.bsky.social · 25/08/2026
They'll join more than 50 international and national experts. Presented in partnership with @sydney.edu.au, @kidscancerinst.bsky.social, Sydney Children's Hospital Network and UNSW the program spans advanced therapeutics, rare diseases, cancer research, genomics, equity and translation.
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Children's Medical Research Institute @cmri.bsky.social · 25/08/2026
Professor Hilda Pickett – Strengthening Sovereign Capability and Commercialisation Professor Robyn Jamieson and Associate Professor Anai Gonzalez-Cordero – Advancing Therapeutics
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Children's Medical Research Institute @cmri.bsky.social · 25/08/2026
Don't miss out on hearing three of our leading researchers at the Luminesce Alliance Conference 2026 – a national conversation on the future of paediatric precision medicine. Early Bird registrations close 1 September. 4–5 November 2026 Register: www.luminesceallianceconference.org.au/register/
luminesceallianceconference.org.au
Register - Luminesce Alliance Conference
Registration Delegate Registration Fees & InclusionsAll prices are quoted in Australian dollars and include GST.Registration fees are based on the date of receipt of payment (not the registration date...
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Children's Medical Research Institute @cmri.bsky.social · 10/08/2026
Well done, Vina!
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Children's Medical Research Institute @cmri.bsky.social · 05/08/2026
It is always fantastic for our scientists to sit down with Dr Karl Kruszelnicki and explain what they do! This time it was CMRI A/Prof Anai Gonzalez Cordero who spoke about her work with stem cells and organoids. Watch the full interview here: youtu.be/kFPZnRj0hVw?si=_aZc-8qgrVx…
Smiling woman in red sweater sitting next to an elderly man wearing colorful glasses and a patterned sweater at a wooden table.
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Children's Medical Research Institute @cmri.bsky.social · 29/07/2026
Congrats to Prof Tony Cesare on being awarded an NHMRC Investigator Grant (L2)! Tony is Head of the Genome Integrity Research Unit at CMRI and his research on how cells protect DNA is driving new approaches to cancer treatment. This grant will support his research over the next 5 years.
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Children's Medical Research Institute @cmri.bsky.social · 28/07/2026
Our scientists shared their work at the recent Westmead Research Showcase. Prof Roger Reddel did the official welcome and researchers Macabe Daley and Daniel De Los Reyes Helices did presentations about their work. Our facilities were also well represented.
Older man in a suit and red striped tie speaking at a podium with a computer monitor in front of him.Man with glasses and beard giving a presentation behind a podium with two monitors and water bottles.Two people smiling and engaging in conversation at a table covered with brochures and informational materials in a casual setting.A group of seven people in business attire stand together for a photo in an empty auditorium with rows of red seats behind them.
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Children's Medical Research Institute @cmri.bsky.social · 24/07/2026
2/2 Read more here: www.cmrijeansforgenes.org.au/news/maddie-...
cmrijeansforgenes.org.au
Maddie Rieworldt's Vision grant winner
New research grant giving hope to children living with telomere-related bone marrow disorders.
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Children's Medical Research Institute @cmri.bsky.social · 24/07/2026
1/2 We are delighted to announced that Dr Ashley Yang has received a three-year fellowship from Maddie Rieworldt’s Vision to offer hope for children living with telomere-related bone marrow disorders. Dr Yang hopes to lay the groundwork for personalised gene therapies for patients.
A researcher in a white lab coat smiles at the camera, standing in a laboratory with blurred shelves and equipment in the background.
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Children's Medical Research Institute @cmri.bsky.social · 03/07/2026
Great to see the work of Professor Hilda Pickett and Dr Madushan Fernando feature in a review article in Trends in Nature Cell Biology. Their review was titled “Telomere heterochromatin-mediated compartmentalization: Where ALT begins’’. Read more here pubmed.ncbi.nlm.nih.gov/42248718
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Children's Medical Research Institute @cmri.bsky.social · 01/07/2026
5/5 A/Prof Gonzalez Cordero says: ‘This award ensures deep engagement with the IRD community remains central to Australia’s research and our translational efforts.'
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Children's Medical Research Institute @cmri.bsky.social · 01/07/2026
4/5 This includes: pubmed.ncbi.nlm.nih.gov/41027690/ onlinelibrary.wiley.com/doi/10.5694/... s3.ap-southeast-2.amazonaws.com/cmri-assets/... www.cmrijeansforgenes.org.au/research/res...
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Children's Medical Research Institute @cmri.bsky.social · 01/07/2026
3/5 Together, Eden and Anai have published several key papers in this space demonstrating their continued leadership in shaping ethical, community centered approaches to stem cell and organoid research in Australia.
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Children's Medical Research Institute @cmri.bsky.social · 01/07/2026
2/5 This award recognises the team’s outstanding work in inherited retinal disease (IRD) community centered research. The grant will strengthen how we support the IRD community to understand emerging stem cell research in ophthalmology and what it means for patients and families.
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Children's Medical Research Institute @cmri.bsky.social · 01/07/2026
1/5 Congratulations to Dr @edenrobertson.bsky.social and Associate Professor Anai Gonzalez-Cordero on receiving a Medical Research Future Fund Stem Cell Therapies Grant.
Two women standing close together outside a building, smiling and posing for a photo in business-casual black outfits.
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Children's Medical Research Institute @cmri.bsky.social · 30/06/2026
An exciting new publication is out revealing new ways to treat drug-resistant #epilepsy. Congratulations to Professor Phil Robinson and his collaborator Professor Adam McClusky for their work published in ACS Publications. Read more here: pubs.acs.org/doi/10.1021/acschembio…
Scientist wearing a light blue shirt standing in a laboratory filled with scientific equipment and chemical bottles.
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Children's Medical Research Institute @cmri.bsky.social · 29/06/2026
3/3 As Prof Jamieson noted, this is a powerful opportunity to apply cutting edge technology to fast track access to sight saving treatments.
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Children's Medical Research Institute @cmri.bsky.social · 29/06/2026
2/3 NSW Health Deputy Secretary, Clinical Innovation and Research, Professor Jean-Frédéric Levesque made the announcement at the NSW Government’s first Non-Animal Technologies Network Vanguard Symposium. This support will help accelerate new therapies for people living with blinding eye conditions.
Five researchers standing in front of exhibition banners at a research showcase, including CMRI and NSW Organoid Innovation Centre displays.
Fluorescence microscopy image of a retinal organoid showing layered cell types in blue, green, red and magenta.
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Children's Medical Research Institute @cmri.bsky.social · 29/06/2026
1/3 Today, Professor Robyn Jamieson received a $200,000 grant to support her innovative use of organoids to better understand retinal disease. @sydney.edu.au Learn more here: www.cmrijeansforgenes.org.au/news/major-w...
Researcher presenting a research program overview slide covering genomics, gene therapy and retinal organoids, with an NSW Government banner visible.
Six researchers posing in a building foyer featuring red marble walls and an Aboriginal artwork, with an NSW Government banner.
Researcher presenting a gene therapy slide for STGD1 treatment at a podium with an NSW Government banner in the background.
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Children's Medical Research Institute @cmri.bsky.social · 11/06/2026
Always great to see our scientists being called upon as experts in the field. This time Prof Hilda Pickett was invited by The Scientist to talk about a recent discovery in the telomere field. Read more: ow.ly/sQkf50Z9L0u
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Children's Medical Research Institute @cmri.bsky.social · 11/06/2026
Here is the updated link to the full story: www.atascientific.com.au/awards/young...
atascientific.com.au
Young Scientist Encouragement Award — May 2026 | ATA Scientific
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Children's Medical Research Institute @cmri.bsky.social · 10/06/2026
Dr Mawj Adam in our GTRU has won an ATA Scientific Encouragement Award for her work in advancing gene therapy strategies for paediatric metabolic liver disorders. Mawj will now present her work at the upcoming Australasian Gene and Cell Therapy Society Biennial Meeting. ow.ly/2OIp50Z9eb2
Confident woman with long dark hair stands with arms crossed in a bright, modern laboratory setting.
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Children's Medical Research Institute @cmri.bsky.social · 05/06/2026
Wonderful to see CMRI’s Prof Hilda Pickett share her world-leading telomere biology research at the European Molecular Biology Organisation conference in Italy. Her advances are shaping our understanding of genome stability and disease—an inspiring moment for Australian science! EMBO
Speaker presenting at EMBL workshop on telomere function and health maintenance, with scientific posters and event details visible.
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Children's Medical Research Institute @cmri.bsky.social · 01/06/2026
Researchers from The Westmead Institute for Medical Research, Westmead Breast Cancer Institute, NSW Health Pathology and CMRI's ProCan® team have published new findings in npj Breast Cancer. Read the publication here: www.nature.com/articles/s41523-026-…
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Children's Medical Research Institute @cmri.bsky.social · 22/05/2026
Congratulations to @lizconnolly.bsky.social on her PhD in Medicine from the @sydney.edu.au. Through her work with the #ProCan team at #CMRI, Liz’s #sarcoma research is helping advance precision #cancer care. We’re proud to help train the next generation of clinician-scientists.
Graduate in black and red academic gown holding a mortarboard, standing on a lawn in front of a historic sandstone university building in bright sunlight.University graduation ceremony inside a grand hall, with a graduate receiving a doctorate on stage as academic staff sit behind and the moment is displayed on a large screen above.
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Children's Medical Research Institute @cmri.bsky.social · 21/05/2026
We’re proud to celebrate Dr Zhaoxiang (Simon) Cai, senior ProCan data scientist, who has been awarded a highly competitive Cancer Institute NSW Fellowship. His groundbreaking AI research is helping transform the future of cancer diagnosis. Read more here: www.cmrijeansforgenes.org.au/news/data-sc...
Man against a light blue background, with on-image text reading “Dr Zhaoxiang Cai” and “Early Career Fellow.” Cancer Institute NSW logo appears in the bottom right corner, with “Cancer Institute NSW” text along the bottom left.
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Children's Medical Research Institute @cmri.bsky.social · 30/04/2026
A team of scientists at CMRI, in collaboration with partners at The Kids Research Institute Australia, has discovered a previously unrecognised lethal genetic neurodevelopmental disorder, with findings published in Acta Neuropathologica. Read more: doi.org/10.1007/s00401-026-03017-2
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Children's Medical Research Institute @cmri.bsky.social · 29/04/2026
3/3 This level of control over retinal cell fate is expected to enhance the precision of retinal disease models and support the development of targeted cell replacement therapies.
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Children's Medical Research Institute @cmri.bsky.social · 29/04/2026
2/3 The study demonstrates that retinoic acid orchestrates cell fate decisions, maturation, and regional patterning, highlighting its central role in establishing retinal identity during human development.
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Children's Medical Research Institute @cmri.bsky.social · 29/04/2026
1/3 In a new publication from CMRI’s Stem Cell Medicine and Computational Biology Units, retinal organoids were used to define the role of retinoic acid (vitamin A) signalling in early human retinal development. Read the full pub: doi.org/10.1038/s414...
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Children's Medical Research Institute @cmri.bsky.social · 24/04/2026
🧬New publication in Clinical Cancer Research: one of the largest tissue proteomic studies in colon cancer! aacrjournals.org/clincancerre... @westmeadinst.bsky.social @sydney.edu.au
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Children's Medical Research Institute @cmri.bsky.social · 24/04/2026
3/3 If you’d like to listen, fast forward to 39.22 minutes in: www.abc.net.au/listen/progr... #ABCRadioEvenings #ChildrensMedicalResearch #CMRI #EyeDisease
abc.net.au
Evenings - ABC listen
Join us for the famous Evenings quiz, a mix of interesting interviews, stories and live music.
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Children's Medical Research Institute @cmri.bsky.social · 24/04/2026
2/3 As a leading clinician-researcher in this space, Professor Jamieson was invited to speak about the breakthroughs transforming patient outcomes and what lies ahead for this cutting-edge area of medicine.
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Children's Medical Research Institute @cmri.bsky.social · 24/04/2026
1/3 We were pleased to hear CMRI Prof Robyn Jamieson featured on ABC Radio’s Evenings program this week, where she shared expert insights on the rapidly advancing field of gene therapy and its impact on restoring vision for Australians living with genetic eye disease.
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Children's Medical Research Institute @cmri.bsky.social · 13/04/2026
The tool can reliably identify common and rare cell populations when analysing complex single-cell data sets and has important potential in disease research and precision medicine.
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Children's Medical Research Institute @cmri.bsky.social · 13/04/2026
Children's Medical Research Institute's Head of Computational Systems Biology, A/Prof Pengyi Yang, has a new publication out today in Molecular Systems Biology which involved developing a new AI method known as Hydra. @springernature.com Full pub here: link.springer.com/article/10.1...
link.springer.com
Interpretable deep generative ensemble learning for single-cell omics with Hydra - Molecular Systems Biology
Single-cell omics enable the dissection of cellular heterogeneity, yet the high dimensionality, inherent noise, and sparsity present significant challenges. These challenges are amplified for rare cel...
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Children's Medical Research Institute @cmri.bsky.social · 24/02/2026
If you'd like to donate to this world-class research you can do so here: www.gofundme.com/f/twentyone-...
gofundme.com
Donate to Support Breakthrough Therapy for Kids with ultrarare Disease, organized by Jens Poessel
Twenty-one children. A rare disease. A real chance. Emil… Jens Poessel needs your support for Support Breakthrough Therapy for Kids with ultrarare Disease
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Children's Medical Research Institute @cmri.bsky.social · 24/02/2026
Thank you to Mira and Charlie Taouk for sharing their heartbreaking story and 10 News + for talking to Professor Leszek Lisowski. You can watch the full story here: 10.com.au/news/nationa...
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Children's Medical Research Institute @cmri.bsky.social · 13/02/2026
Sometimes science and art intersect! Congratulations to Leigh Nicholson from CMRI who won an Early-Mid Career Research award for her poster at the recent Light Microscopy Australia Symposium at the University of Sydney (USYD) for her incredible images highlighting our research.
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Children's Medical Research Institute @cmri.bsky.social · 12/02/2026
or read the story on our website: www.theage.com.au/national/aud...
theage.com.au
Audrey’s rare cancer grows like a frayed shoelace that can’t be tied
Improved treatment for rare and aggressive “ALT cancers” that claim the lives of 5000 to 7000 Australians each year is the focus of $5 million in research funding.
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Children's Medical Research Institute @cmri.bsky.social · 12/02/2026
You can read more here: www.cmrijeansforgenes.org.au/news/synergy...
cmrijeansforgenes.org.au
Synergy Grant to develop first-in-world treatments for…
The project focuses on identifying precision therapies for ALT-dependent cancers.
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Children's Medical Research Institute @cmri.bsky.social · 12/02/2026
We’re very grateful to the National Health and Medical Research Council for awarding CMRI’s Professor Hilda Pickett and a team of cancer researchers $5 million for their work to develop new treatments targeting some of the most aggressive and difficult to treat cancers.
Person seated at a laboratory bench, wearing a dark blazer over a dark top. The background shows shelves with scientific equipment and supplies in a bright, modern lab.
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Children's Medical Research Institute @cmri.bsky.social · 19/01/2026
5/5 Children's Medical Research Institute is leading this project in collaboration with Leicester Mesothelioma Research Programme (UK), NETMESO Research Group (France), and Asbestos and Dust Diseases Research Institute (ADDRI, Australia).
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Children's Medical Research Institute @cmri.bsky.social · 19/01/2026
4/5 The team will also explore why some patients don’t respond to immunotherapy, paving the way for new therapeutic strategies.
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