Reposted by Charlotte Kirchhelle
Plants balance iron and immunity at the cell surface. Our new paper reveals how ubiquitin reorganizes the receptor SRF3 to coordinate both, and how this co-ordination works. Huge shoutout to Matt Platre who spearheaded and drove this tour de force! www.science.org/doi/10.1126/...
science.org
SRF3 couples cellular iron homeostasis and defense responses through ubiquitin-dependent nano-organization
Iron homeostasis is a central component of host defense responses. In mammals, iron availability is rapidly adjusted through receptor mediated pathways, whereas it remains unclear how plants regulate iron homeostasis during the earliest stages of immune ...