Beneficial gut bacteria help newborns activate antimicrobial defenses, offering new insight into early-life immunity.

Researchers uncovered key signals linked to graft rejection, offering a path toward earlier detection and intervention.

Cincinnati Children's research leader Tina Cheng co-authors child health policy editorial published in STAT.

Moderate-to-severe chorioamnionitis and cerebellar abnormalities were independently associated with higher autism risk in infants born before 32 weeks' gestation, according to new research led by experts at Cincinnati Children's.

Earlier stem cell transplants may improve survival for youth with Shwachman-Diamond syndrome when high-risk features emerge, according to a study led by an expert at Cincinnati Children's and publishe...

Researchers identify how glutamine shapes inflammatory T cell activity and liver inflammation during MASLD progression.

The AAP honor recognizes Cheng’s decades of service to pediatrics and work to improve health outcomes for children and families.

Cradle Cincinnati’s community-led collaboration helped Hamilton County cut infant deaths and move below the national infant mortality average.

Researchers discovered how a common lupus risk variant may boost antiviral defenses while increasing autoimmunity risk.

Anatool, a new clinical support tool developed by FARE in collaboration with Cincinnati Children’s emergency medicine expert Tim Dribin, MD, helps healthcare professionals recognize and treat anaphylaxis using international consensus guidance.

In recognition of Childhood Cancer Awareness Month, Cincinnati Children’s highlights several research advances led by cancer experts here, including work to develop FLASH proton therapy, evaluate safer CAR T-cell therapy, and investments to expand gene and cell therapies.

An intervention designed to enhance executive functioning skills and self-management care for adolescents with type 1 diabetes reduced stress and burnout while increasing quality of life, according to a study in The Journal of Pediatrics. Avani C. Modi, PhD, pediatric psychologist at Cincinnati Children’s Hospital, and colleagues conducted a pilot randomized controlled trial to evaluate

Cincinnati Children’s researchers report that KRAS inhibitors may offer a promising new strategy for shrinking NF1-related nerve tumors, based on preclinical mouse-model findings.

Scientists have learned a great deal about the specialized T cells that emerge after activation, including effector, memory and exhausted populations. Yet a fundamental question has remained: how much of a T cell’s future success is determined before it ever encounters a virus, tumor or vaccine?

Study finds clinicians often disagree on common physical exam findings used to diagnose pneumonia in children, underscoring the need for more reliable diagnostic tools.

Researchers uncovered a pathway linking vitamin A signaling to tuft cell development and type 2 immune responses.

Abstract was not provided for this article.

Learn why Cincinnati Children’s has remained the ideal place to pursue both research and medicine for this pulmonary pathologist.

Indigo-enriched indoor lighting may help prevent childhood myopia by restoring wavelengths missing from standard lighting.

Researchers identified a pathway linking inflammation to barrier dysfunction in EoE, supporting current and future therapies.

New genomic approach reveals how genetic risk influences genes in rare immune cells through long‑distance DNA interactions.

Over 1 million people a year die from diarrheal disease. Nearly half are kids under age 5. A new vaccine in trials offers great hope.

Analysis of nearly 16,000 infections reveals distinct symptom patterns and outcomes across common respiratory viruses.

Cincinnati Children’s receives a $38.4 million NIH grant renewal to expand Bench to Bassinet, a national congenital heart disease genomics program.

Cincinnati Children’s researchers developed an address-level model that links housing, crime, eviction, birth, and neighborhood data to pediatric hospitalization risk, offering a more precise framework for place-based child health interventions.

A model can predict which children/adolescents who received an epinephrine dose for anaphylaxis before ED arrival are at risk for receiving it again after ED arrival using prehospital data, according ...

A new Cincinnati Children’s study shows BRACHA-S can help predict agitation risk in pediatric psychiatric emergency visits.

One of the nation's top leukemia researchers will guide Cincinnati Children's cancer and blood disease research and scientific collaboration with UC Cancer Center.

A Cincinnati Children’s-led study finds that NICU-based mental health support can reduce anxiety, stress and depression among parents, suggesting these services should become part of standard neonatal care.

Gene therapy restored key fragile X syndrome traits in mice, supporting future work on FMR1 replacement as a potential disease-modifying treatment.

Multi-model study shows host-directed therapies reduce inflammation and outperform anti-inflammatory care in TB meningitis.

Learn about our Rheumatology division's first female faculty, whose research in juvenile arthritis helped shaped pediatric autoimmune research worldwide.

Cincinnati Children’s researchers will help lead the BOND trial, a multicenter study testing ways to support parent well-being, breastfeeding and infant development after congenital heart disease diagnosis.

Researchers map how Epstein-Barr virus interacts with human DNA, offering new insight into gene regulation and disease risk.

Study finds critically ill children are rarely seen in most EDs and few can be redirected, highlighting need for targeted pediatric readiness.

A phase 2 clinical trial involving Cincinnati Children’s researchers found an oral Shigella vaccine candidate provided 89% protection, supporting further studies to combat a major global cause of diarrheal disease.

A large study finds antibiotics do not improve preschool wheezing, supporting evidence‑based care without routine antibiotic use.