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CicinSainLab

@cicin-sainlab.bsky.social
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GfV - Gesellschaft für Virologie @gesvirologie.bsky.social · 22/10/2025
🦠 Abstract submission for the 35th Annual Meeting of the Society for Virology is open! Share your research with the virology community and help shape the scientific dialogue next year in Heidelberg. 🕐 Deadline: Jan 4, 2026 🔗 virology-meeting.de/programme-ab... #GfV2026 #virology #virologymeeting
virology-meeting.de
Abstract submission
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CicinSainLab @cicin-sainlab.bsky.social · 04/09/2025
This is important and needs to be shared everywhere. American Scientific Associations working in the field of Infection and Immunity have said that enough is enough and are calling for RFK Jr. Resignation: www.idsociety.org/news--public... This is an act of civil courage that I strongly support.🧪
idsociety.org
Joint statement calling for Secretary Kennedy resignation
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Dr. Lucky Tran @luckytran.com · 31/08/2025
Governor Jared Polis says on a reddit AMA that Colorado will fix it so that people can access COVID vaccines without a prescription within the next few days.
drubbitz
Have your decisions contributed to Colorado becoming a "prescription-only" state for the covid vaccine?

jaredpolis
We are going to do everything we can to make sure that people can access the vaccine of their choice without a prescription, and I think this will happen soon. I was hoping we could wrap it up on Friday. Hopefully in the next few days we will get this cleared up.
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Dr. Lucky Tran @luckytran.com · 31/08/2025
Source:
nmhealth.org
State health department issues COVID-19 vaccine health order
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CicinSainLab @cicin-sainlab.bsky.social · 28/08/2025
This is so sad, because avoidable. We know much more now than 45 years ago. Vaccine technologies and infection tracing are drastically improved. Yet, fight against infections has become a partisan and ideological issue, slowing real-world deployment of medical knowledge. Politics is failing us.
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CicinSainLab @cicin-sainlab.bsky.social · 28/08/2025
I've been elected as speaker of the Working Group on #Vaccines of the German #Immunological Society (@dgfi-org.bsky.social). I thank all members who voted & look forward to the upcoming mandate. Jan 14-16 '26, is our next #Vaccine #Workshop at @helmholtzhzi.bsky.social in Braunschweig. Stay tuned! 🧪
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CicinSainLab @cicin-sainlab.bsky.social · 25/08/2025
Interesting take. It rings a bell with me. Antivaxers refusing vaccines is not the fault of imperfect communication by scientists. Antivaxer groups have agency and thus responsibility for the growth in vaccine hesitancy. This is not just scientists that fail to reach impossible standards of proof.🧪
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CicinSainLab @cicin-sainlab.bsky.social · 15/08/2025
I was asked by the international office of Deutsche Welle for a comment of the funding cuts for mRNA vaccine development (linke below). My lab is developing a vaccine technology that competes with the mRNA one, and I have no personal incentives to advocate for it. 1/2 🧪 www.dw.com/en/why-us-bu...
dw.com
Why US budget cuts could derail future mRNA vaccine progress – DW – 08/14/2025
US Government cuts to mRNA vaccine research could set back technological advances and reduce access to therapies, while raising their costs.
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CicinSainLab @cicin-sainlab.bsky.social · 26/07/2025
I am at the International #Herpesvirus Workshop (IHW) in Berlin, where the cream of the #herpes science crop gathers this year to share data and ideas (hopefully, not herpes #viruses). I look forward to the talks and may post under #IHW some thoughts on the most interesting talks by my colleagues.🧪
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CicinSainLab @cicin-sainlab.bsky.social · 26/07/2025
Paul Offit has a detailed takedown on the new misguided #vaccine policies of RFK Jr. pauloffit.substack.com/p/rfk-jrs-cr... In brief, it is a combination of arrogance with willful ignorance of scientific #evidence. An entire change in policies is justified by a single outlier paper from 1980. 1/2 🧪
pauloffit.substack.com
RFK Jr.’s Cruelest Cut of All
Robert F. Kennedy Jr. just eliminated U.S. vaccine funding for the world’s children. Why?
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CicinSainLab @cicin-sainlab.bsky.social · 25/07/2025
Filter the microplastic from your blood through a plastic filter! What could possibly go wrong?
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CicinSainLab @cicin-sainlab.bsky.social · 14/07/2025
This is important - there is vaccine derived polio in German sewage water. Please share in your networks these information for MDs and parents (only in German, sorry). bsky.app/profile/rki....
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CicinSainLab @cicin-sainlab.bsky.social · 06/07/2025
We started the Cres conference with a great talk by Tony Hunter, spanning his work over 5+ decades, from early identification of protein kinases as drivers of cell transformation and cancer to his recent work on PIN1 and cholesterol biosynthesis in bladder cancer pubmed.ncbi.nlm.nih.gov/39808064/
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CicinSainLab @cicin-sainlab.bsky.social · 06/07/2025
I am attending the Frontiers in Drug Discovery workshop on the beautiful island of Cres, Croatia in the next few days. Even more beautiful is the lineup of speakers, with big names in cell and molecular biology, immunology and biochemistry. Kudos to @idikic.bsky.social, I. Stagljar and T. Lenac 1/2
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CicinSainLab @cicin-sainlab.bsky.social · 25/06/2025
While LLM are useful and make us much more efficient, thez also make us complacent and kinda lazy. Now there is more evidence on that. time.com/7295195/ai-c... h/t @mjkellner.bsky.social 🧪
time.com
ChatGPT's Impact On Our Brains According to an MIT Study
The study, from MIT Lab scholars, measured the brain activity of subjects writing SAT essays with and without ChatGPT.
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Dan Garisto @dangaristo.bsky.social · 24/06/2025
NEW: NSF will be kicked out of their building. Announcement will be made tomorrow by HUD Sec. and Governor of VA. HUD will take over the NSF building over the next two years. NSF staffer: "There is no planning for NSF, no identified future location, appropriation for a new building or a move."
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Jesse Hawken @jessehawken.bsky.social · 24/06/2025
"You're laughing? Big Balls lost his government job and you're laughing?"
Robert De Niro in JOKER as a talk show host
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CicinSainLab @cicin-sainlab.bsky.social · 20/06/2025
Like every other Friday, today my lab has a journal club. We will discuss a new paper by the @virusesimmunity.bsky.social Iwasaki lab on Ig responses to endogenous retroviruses. I write this to highlight an AI tool for rapid analysis of PDF manuscripts notebooklm.google.com. We tried it and... 1/2🧪
notebooklm.google.com
Sign in - Google Accounts
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CicinSainLab @cicin-sainlab.bsky.social · 20/06/2025
This is a very nice report on the local TV network (German only) on our efforts to develop a #biotech platform that allows modular development of #vaccines eliciting non-waning immunity against an array of potential targets. Our first aims is a vaccine against #RSV. Others will follow. Stay tuned.🙂
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CicinSainLab @cicin-sainlab.bsky.social · 12/06/2025
Very proud of my former student Zeeshan, who has identified a genetic determinant of T-cell memory formation. www.nature.com/articles/s41... He & the team of G. Belz show that GFI1 is critical for the establishment & maintenance of antigen specific T-cell populations. Why does this matter? 1/3🧪
nature.com
GFI1-driven transcriptional and epigenetic programs maintain CD8+ T cell stemness and persistence - Nature Immunology
Belz and colleagues show that GFI1, a transcriptional repressor that recruits histone-modifying enzymes, is necessary for the generation and maintenance of stem cell memory CD8+ T cells.
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CicinSainLab @cicin-sainlab.bsky.social · 06/06/2025
The @gesvirologie.bsky.social has now published g-f-v.org/en/fuenf-jah... addressing among others the merits of Great Barrington Declaration, which advocated for ending COVID-19 lockdowns, focused protection of vulnerable, while allowing low-risk groups to live normally & build natural immunity. 1/5
g-f-v.org
Five years of COVID-19: Comments from the Society of Virology on dealing with the COVID-19 pandemic in Germany | Society of Virology
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CicinSainLab @cicin-sainlab.bsky.social · 04/06/2025
I gave a talk on COVID vaccines yesterday. I combined in my introduction slide two key meta-analyses, with the good and the bad news about COVID vaccines. While mRNA and some protein vaccines outperform infection in terms of antibody responses and protectivity, this does not last that long. 1/2🧪
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CicinSainLab @cicin-sainlab.bsky.social · 03/06/2025
The Virological Society (Gesellschaft für Virologie - GfV), along with the German Society for Infectiology has issued a statement on lessons learned from the last pandemic. While it was originally issued in German, it is now also available in English. You can find it here:🧪 g-f-v.org/en/fuenf-jah...
g-f-v.org
Five years of COVID-19: Comments from the Society of Virology on dealing with the COVID-19 pandemic in Germany | Society of Virology
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The Binder Lab (DKFZ Heidelberg) @thebinderlab.bsky.social · 03/06/2025
Second day of the @www.helmholtz.de #COVIPA Symposium on Pandemic Preparedness. Really excited now to listen to Leif Sander @sanderlab.bsky.social on the role of innate immunity in respiratory viral infections 🤩
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CicinSainLab @cicin-sainlab.bsky.social · 24/05/2025
Really grateful to my host Milena for her hospitality at the Pasteur Institute. Amazing research environment and facilities, and awesome faculty. I look forward to more opportunities for future joint projects.
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CicinSainLab @cicin-sainlab.bsky.social · 15/05/2025
Great success for our team! This provides us another million in funding to develop our vaccine concept in pre-clinical models. The idea is based on a modular CMV vaccine vector that forms a slow-releasing antigenic depot, and thus obviates the need for vaccine boosters. Stay tuned for more.
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Reposted by CicinSainLab
Saganism @sagan.bsky.social · 02/05/2025
Dr. Anthony Fauci urges Americans not to accept "Normalization of Untruths".
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CicinSainLab @cicin-sainlab.bsky.social · 01/05/2025
The #ECV in BEautiful Croatia has come to an end. My highlight was the acceptance speech of Stipan Jonjić, my PhD mentor and friend, who was awarded the Yearly Award of the European Virology Association. Stipan made tremendous advances to our understanding of NK and T cells in virus control, &...1/2
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CicinSainLab @cicin-sainlab.bsky.social · 29/04/2025
🧪 #ECV Another herpesvirus doing a lot of severe & severely unappreciated damage to the brain is the Epstein Barr virus (EBV). E. Puchamer-Stockl from Vienna told us at the virology conference of EBV's effect on multiple sclerosis (MS), where people with many antibodies against EBV developed MS. 1/2
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CicinSainLab @cicin-sainlab.bsky.social · 29/04/2025
🧪 #ECV Ilija Brizic was telling us today about the impact of latent #CMV #infection on #brain function. Congenital CMV infection is the most common infectious cause of malformations and disabilities. 1:1000 newborns will be hindered for life due to such infections, where no vaccine is available. 1/n
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CicinSainLab @cicin-sainlab.bsky.social · 28/04/2025
#ECV 🧪 Olivier Schwartz, the former director of the Pasteur Institute, showed that HKU1, one of the 4 endemic #coronavirus, present among people since centuries, uses #TMPRSS2 as the receptor for entry into cells. TMPRSS2 is a protease critical for processing viral proteins, like spike or HA... 1/2
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CicinSainLab @cicin-sainlab.bsky.social · 28/04/2025
#ECV 🧪 A. Marzi showed us that an rVSV vaccine against Ebola Sudan that was until very recently spreading among peoplein Uganda protects experimentally infected monkeys from this virus. Yet importantly, the vaccine against Ebola-Zaire was not only inefficient, but accelerated disease and death. 1/2
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CicinSainLab @cicin-sainlab.bsky.social · 28/04/2025
#ECV 🧪T. Pietschmann talking about efforts to develop a vaccine against HCV (hepatitis C virus). Just like with HIV, we now have efficient drugs against HCV, but there is no vaccine. This is due to the enormous diversity of circulating HCV strains. To develop a vaccine, we would need antigens... 1/n
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CicinSainLab @cicin-sainlab.bsky.social · 28/04/2025
#ECV The presentation by S. Pöhlmann was a tour de force covering lots of their work on SA-CoV-2 spike, and its role in entering cells. They assessed in detail the alternative receptor TMEM106b for entry, which was shown to mediate entry instead of ACE-2. www.sciencedirect.com/science/arti.... Yet..
sciencedirect.com
TMEM106B is a receptor mediating ACE2-independent SARS-CoV-2 cell entry
SARS-CoV-2 is associated with broad tissue tropism, a characteristic often determined by the availability of entry receptors on host cells. Here, we s…
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CicinSainLab @cicin-sainlab.bsky.social · 26/04/2025
The European Congress of #Virology, ECV, starts soon in Cavtat, Croatia. eusv-congress.eu I look forward to meeting so many old colleagues and friends and hearing about the their new research. I wish to thank the organizers for this fantastic lineup of speakers and the choice of this gorgeous venue.
eusv-congress.eu
ECV: ECV • eusv-congress.eu
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Barack Obama @barackobama.bsky.social · 15/04/2025
Harvard has set an example for other higher-ed institutions - rejecting an unlawful and ham-handed attempt to stifle academic freedom, while taking steps to make sure students can benefit from an environment of intellectual inquiry, rigorous debate and mutual respect. Let’s hope others follow suit.
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Flo Débarre @flodebarre.eurosky.social · 08/04/2025
There have been many lab leak articles in the media recently, but none had actual new data In a new preprint, @zachhensel.bsky.social and I analyze early COVID-19 cases sequence data that have been overlooked so far. These new data continue to point to a natural origin ▫️1/7 doi.org/10.1101/2025...
Entre invention de preuve, faux témoignage, et recherche falsifiée.

Figure 1 from the preprint, showing the distribution of collection dates of the newly uncovered data and comparing it to the distribution of previous sequences collection dates; earliest new one is in early Jan. 

Caption: 
Figure 1. Temporal distribution of initial dataset and newly added sequences (samples collected between 24-Dec-2019 and
15-Feb-2020). Sequences in the initial dataset from market-linked samples and within a single familial cluster are colored green and
purple, respectively. Other sequences in the initial dataset are colored orange. Newly added sequences are colored blue. The arrow
indicates the earliest sequence in added data, which is market-linked.
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GfV - Gesellschaft für Virologie @gesvirologie.bsky.social · 26/03/2025
Es ist ein Meinungs-Artikel, aber diese "Meinung" beruft sich sehr wenig auf Fakten. Wir würden daher gerne ein paar Dinge aufklären: 1) „In den Vereinigten Staaten registrierten Regierungsbehörden" in vier Jahren "mehr als 1100 Laborvorfälle mit Bakterien, Viren und Toxinen“ 1/8
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CicinSainLab @cicin-sainlab.bsky.social · 13/03/2025
Recently, a lot of media gave attention to a report of BND, the main German intelligence agency, about a supposed COVID lab-leak origin. The report is from 2020, & claims that the lab leak is likely to a level of 80-95%. A balanced statement on the matter: www.helmholtz-hzi.de/en/media-cen... 1/3🧪
helmholtz-hzi.de
Fabian Leendertz on the current reporting on the origin of the SARS-CoV-2 virus
Statement by the Director of the Helmholtz Institute for One Health in Greifswald on the origin of the SARS-CoV-2 virus
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CicinSainLab @cicin-sainlab.bsky.social · 13/03/2025
Many thanks to M. Jakobsen who led the team that identified a robust antigen-presenting function of plasmacytoid dendritic cells (pDC). www.cell.com/cell-reports... pDC have been known for interferon responses to infections. The new study shows that they also support adaptive T cell responses. 🧪
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CicinSainLab @cicin-sainlab.bsky.social · 12/03/2025
A measles epidemic that cannot be contained is absolutely unacceptable for a developed country in the 21st century. Words fail me. 😡
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CicinSainLab @cicin-sainlab.bsky.social · 10/03/2025
Both Luka Modric and Luka Cicin-Sain can play football.
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CicinSainLab @cicin-sainlab.bsky.social · 07/03/2025
The 34th annual meeting of the @gesvirologie.bsky.social is coming to an end. It was instructive and fun. We learned a lot about #viruses from colleagues across Germany and the world. We look forward to the next meeting, taking place in Heidelberg next March. I'll be there, hope to see you too.
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CicinSainLab @cicin-sainlab.bsky.social · 06/03/2025
Let me just point here that transGENIC mice are not the same as tranGENDER mice. Transgenic mice are those where we introduce a gene into one of their chromosomes to study mechanisms of disease and find cures. Transgender mice, as described by D. Trump in his recent congress speech, do not exist.🧪
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GfV - Gesellschaft für Virologie @gesvirologie.bsky.social · 06/03/2025
Elisabeth Puchhammer-Stöckl opens the first plenary session of the day with her talk about Herpesviruses as a potential key to neurological diseases. (CR)
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CicinSainLab @cicin-sainlab.bsky.social · 05/03/2025
@gesvirologie.bsky.social 2025: The Löffler-Frosch Medal, a symbol of lifetime achievements in the field of virology, has gone to Thomas Mettenleiter from the Friedrich Löffler Institute. Highly deserved! Thank you Thomas for your decade long comittment to advancing science.
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CicinSainLab @cicin-sainlab.bsky.social · 04/03/2025
@gesvirologie.bsky.social Jahrestagung 2025: E. Neugebauer from the Full lab showed a crucial role for a host cell factor named Dux4 in herpesviral replication. DUX4 is expressed at earliest stages of embryonic developemnt. Or after herpes infection. Read more here: www.nature.com/articles/s41... 🧪
nature.com
Herpesviruses mimic zygotic genome activation to promote viral replication - Nature Communications
Neugebauer et al. show activation of the usually silenced embryonic factor DUX4 by herpesviruses in vitro and in patients, and demonstrate that depletion of DUX4 by nanobody degraders abrogates viral ...
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CicinSainLab @cicin-sainlab.bsky.social · 04/03/2025
We start the 34th Annual meeting of the Virological Society @gesvirologie.bsky.social, this year in Hamburg. Many colleagues from the Swedish Virological Society are joining us. The first plenary is on Zoonoses with Sandra Ciesek (Frankfurt), Eva Haris (UC Berkeley) and Ake Lundqvist (Uppsala).
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GfV - Gesellschaft für Virologie @gesvirologie.bsky.social · 04/03/2025
How can medical virology quickly adapt scientifically and diagnostically to a pandemic caused by a new pathogen? Examples from Covid-19 – Sandra Ciesek recapitulates the work of her institute in the first months of the pandemic.
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Randall Munroe @xkcd.com · 26/02/2025
RNA xkcd.com/3056
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