iiinova — where your digital self keeps evolving

Christos Argyropoulos MD PhD @christosargyrop.mastodon.social.ap.brid.gy · 15/10/2026

Life sciences has been hallucinating facts and theories for a while and it is only through experimentation we learn. AI will just connect plausible, probable, factually false and truth statements into a grand hallucination. Live your Myth in Fable

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Christos Argyropoulos MD PhD @christosargyrop.mastodon.social.ap.brid.gy · 11/10/2026

Kimi K3 "bribing the hamster" hits again! (This is the AGI you were promised by the #AI scammers, people)

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Christos Argyropoulos MD PhD @christosargyrop.mastodon.social.ap.brid.gy · 08/10/2026

Group thinking when the group is not thinking, is bad.

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Christos Argyropoulos MD PhD @christosargyrop.mastodon.social.ap.brid.gy · 06/10/2026

I bought these drives 1.5 - 2 years ago, inflation is real

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Christos Argyropoulos MD PhD @christosargyrop.mastodon.social.ap.brid.gy · 06/10/2026

I honestly believe if Intel had not killed the Optane drives in 2022 and we had the equivalent of the 905P over a PCI5.0 we would have had usable 00s B - trillion parameter local models

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Christos Argyropoulos MD PhD @christosargyrop.mastodon.social.ap.brid.gy · 30/09/2026

To see why the AI math are not matching, ask any cheerleading botlicker about what the end game should look like. They will tell you subscriptions (which they value at $100/month). That is ~450B a year if we everyone gets one which is the size of the US home improvement industry.

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Reposted by Christos Argyropoulos MD PhD

petersuber @petersuber.fediscience.org.ap.brid.gy · 29/09/2026

Update. "Dutch Government is the latest to ditch Microsoft — US sanctions push Netherlands towards home-grown NixOS-based software." www.techradar.com/pro/dutch-governm… […]

fediscience.org

Original post on fediscience.org

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Christos Argyropoulos MD PhD @christosargyrop.mastodon.social.ap.brid.gy · 28/09/2026

From an interaction at X. Northern Ireland remoces the requirement for covid19 testing of symptomatic staff working in clinical areas including those with immunocompromised patients […] [Original post on mastodon.social]

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Christos Argyropoulos MD PhD @christosargyrop.mastodon.social.ap.brid.gy · 28/09/2026

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Reposted by Christos Argyropoulos MD PhD

Glyph @glyph.im · 27/09/2026

The software industry's original sin was "no warranty, even the implied warranty of merchantability", even on literal products for sale. Every evil we have visited upon the world — clickwrap licenses, instagram anorexia, AI dystopia — is downstream of the generalized ability for software to […]

mastodon.social

Original post on mastodon.social

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Christos Argyropoulos MD PhD @christosargyrop.mastodon.social.ap.brid.gy · 24/09/2026

There is wisdom in buying 2 Hirsch/yubi keys at the same time. Having FA the purchase part, I have just FO the wisdom

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Christos Argyropoulos MD PhD @christosargyrop.mastodon.social.ap.brid.gy · 23/09/2026

One of the things that still to this day puzzle me is why statisticians don't deconstruct various AI tools to map them to existing constructs/models/methods of their trade. It would have become rather obvious that some (or even all) of the AI are rebranded statistical models, which in turn would […]

mastodon.social

Original post on mastodon.social

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Christos Argyropoulos MD PhD @christosargyrop.mastodon.social.ap.brid.gy · 20/09/2026

This is going to be a long night, the chatbots need to be reminded frequently that #Rstats + #Perl > #Python #Bioinformatics #AI

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Christos Argyropoulos MD PhD @christosargyrop.mastodon.social.ap.brid.gy · 19/09/2026

This is gonna be my response to our family piano teacher (I am the only one who is not taking lessons) when she suggests I take up lessons: let's wait after death.

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Christos Argyropoulos MD PhD @christosargyrop.mastodon.social.ap.brid.gy · 16/09/2026

Topped up last week : 80.15 dollars for 15.875 gallons of the 91 octane gas ie around 5.09 gallons to the dollar. Seems price went up slightly today 🥳😎

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Christos Argyropoulos MD PhD @christosargyrop.mastodon.social.ap.brid.gy · 14/09/2026

In other news, Trump calls out the FUD BS of the AI trio. What are time to be alive! "Trump says 'very negative forces' raising exaggerated concerns over AI" www.reuters.com/world/europe/trump-…

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Christos Argyropoulos MD PhD @christosargyrop.mastodon.social.ap.brid.gy · 13/09/2026

When the time comes, will you defend the right of the people to multiply matrices? #Alignment #AI #scam #regulatorycapture

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Christos Argyropoulos MD PhD @christosargyrop.mastodon.social.ap.brid.gy · 13/09/2026

Time to regulate GEMM and GEMV for safety in the name of #AI alignment. Anyone using #BLAS without a license especially if they are running models locally will go to Gitmo

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Christos Argyropoulos MD PhD @christosargyrop.mastodon.social.ap.brid.gy · 12/09/2026

If I were to be a disruptive and dismissive asshole, I'd point out that the Navier Stokes solution is a gimmick to make the numpties lose $ on the AI IPO since all work in fluid mechanics that matters is done through numerical calculations. Solve cancer or go home

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Christos Argyropoulos MD PhD @christosargyrop.mastodon.social.ap.brid.gy · 10/09/2026

The Venn diagram of Personalized Medicine/multiomica fundamentalists and AI jihadis is a cycle

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Christos Argyropoulos MD PhD @christosargyrop.mastodon.social.ap.brid.gy · 08/09/2026

We should probably do away with HIPAA as is and put the fines and long term imprisonment terms without parole on the people who use data they were not supposed to have.

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Christos Argyropoulos MD PhD @christosargyrop.mastodon.social.ap.brid.gy · 06/09/2026

I was monitoring my #KimiK3 sessions in the morning by looking at the thinking trace, when I saw this unconnected to anything else really: "Bribing the hamster".

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Christos Argyropoulos MD PhD @christosargyrop.mastodon.social.ap.brid.gy · 05/09/2026

Very pleased with Kimi K.3 which I took for a ride today via #GithubCopilot. Good questions, solid plans, efficient, token frugal implementations in a multilanguage project with multiple branches: C, #Python, #Perl, #rstats #make. It handled documentation needs too. #KimiK3 FTW

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Christos Argyropoulos MD PhD @christosargyrop.mastodon.social.ap.brid.gy · 05/09/2026

Simply brilliant (from "The Volatile Mermaid" at Bluesky)

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Christos Argyropoulos MD PhD @christosargyrop.mastodon.social.ap.brid.gy · 05/09/2026

I never followed the genetic data on LP(a) but apparently there is so much moaning that it betrayed us (or rather the cardiologists and 2 pharmas) so I have got to ask: were the genetic data , garbage polygenic risc scores, mendelian randomization, or something equally worthless?

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Christos Argyropoulos MD PhD @christosargyrop.mastodon.social.ap.brid.gy · 02/09/2026

AI slop will never be a match to p-value hacking research slop... until we unleash the AI to automate the p-value hacking in a manner that combines the small p, with massive ego stroking #AI hallucinating text. #stats

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Christos Argyropoulos MD PhD @christosargyrop.mastodon.social.ap.brid.gy · 30/08/2026

I find the #AI clunkers useful when automating performance benchmarks using 3 context markdown files: ✔️#JSON related one about configuration/build/run matrix 🏃‍♂️#Perl to run the benchmarks/collect telemetry 👁#Rstats to visualize/analyze Even cheap/free models work!

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Christos Argyropoulos MD PhD @christosargyrop.mastodon.social.ap.brid.gy · 30/08/2026

This is an awesome paper and why we will likely have to pivot away training the AI clunkers on unvetted content

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Christos Argyropoulos MD PhD @christosargyrop.mastodon.social.ap.brid.gy · 29/08/2026

Milo Yiannopoulos being detained by ICE for residing illegally in the US will break both the MAGA and the woke mind. Perhaps it is time for both to realize that one cannot selectively choose when to apply the law? Or don't complain when it is selectively applied by the other?

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Christos Argyropoulos MD PhD @christosargyrop.mastodon.social.ap.brid.gy · 26/08/2026

I regret asking the clunker (GPT5.6 Terra) to help with syncing the README.md file of my repo with the existing codebase. It now speaks like a lawyer or a drug commercial

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Christos Argyropoulos MD PhD @christosargyrop.mastodon.social.ap.brid.gy · 26/08/2026

💥#AI models now work reasonably well to be useful automations across many domains 😲the <50 TB of memory used to train a frontier LLM is equivalent to < 1 year of Pornhub’s new content. 😥The mere fact there is more porn than knowledge speaks volume about our stalling progress

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Reposted by Christos Argyropoulos MD PhD

Christos Argyropoulos @christosargyrop.mast.hpc.social.ap.brid.gy · 24/08/2026

Why #microbenchmarks require statistical analysis. The screenshots are results from my repo github.com/chrisarg/bench_popcount of alternative computational for the popcounts under different optimization. (-O0, -O3, -O3 -flto). Is it the algorithm, the compiler or noise the driver? #hpc

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Christos Argyropoulos MD PhD @christosargyrop.mastodon.social.ap.brid.gy · 24/08/2026

I am fed up with efficiency cores in desktop and laptop products when deployed in regulated environments.

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Christos Argyropoulos MD PhD @christosargyrop.mastodon.social.ap.brid.gy · 22/08/2026

Winter disease in August, these people are beyond a joke

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Reposted by Christos Argyropoulos MD PhD

Christos Argyropoulos @christosargyrop.mast.hpc.social.ap.brid.gy · 20/08/2026

#Microbenchmarking time😗 Wrote a small benchmark of population counts (github.com/chrisarg/bench_popcount) wrapping the libpopcnt library (github.com/kimwalisch/libpopcnt) and implementations of the Harley Searle algorithm(https://arxiv.org/abs/1611.07612) using portable […]

mast.hpc.social

Original post on mast.hpc.social

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Christos Argyropoulos MD PhD @christosargyrop.mastodon.social.ap.brid.gy · 15/08/2026

This is an interesting paper... Hypothesis : IFN from flu suppresses COVID, but COVID either does not induce as much IFN to suppress flu , and perhaps (as has been inferred for a while) reduces immune competence ➡️ subsequent flu & other infections ⬆️? […]

mastodon.social

Original post on mastodon.social

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Christos Argyropoulos MD PhD @christosargyrop.mastodon.social.ap.brid.gy · 12/08/2026

Weird, I thought covid is the sniffles. I wonder what the incidence of colon cancer, IgA nephropathy and inflammatory bowel disease are like nowadays www.bloomberg.com/news/articles/202…

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Christos Argyropoulos MD PhD @christosargyrop.mastodon.social.ap.brid.gy · 11/08/2026

This #metanalysis of creatine supplementation on kidney function which concluded "Creatine ... was associated with a small but ... increase in serum creatinine (MD: 0.07 µmol/L; 95% CI: 0.01 to 0.12; p = 0.03)" mixed the units in the text & the effect is ⬆️ than the authors think

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