iiinova — where your digital self keeps evolving

Reposted by Chengchen Li (Cherry)

Hutlab @hutlab.bsky.social · 18/06/2026

Thank you @ihmc2026seoul.bsky.social for organizing IHMC this year at Seoul and inviting Curtis to speak. Also pictured are Cherry and Yan who are lab alumni and also attended the conference!

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Reposted by Chengchen Li (Cherry)

Niranjan Nagarajan @niranjantw.bsky.social · 28/04/2025

Many exciting results to follow-up on! 1. The skin microbiome has unique “types” in every site - we call them dermotypes. The underarm has as many as 5 distinct ones defined by diverse microbes. We built ML classifiers to predict them w/ near-perfect accuracy with 5 species!

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Reposted by Chengchen Li (Cherry)

Niranjan Nagarajan @niranjantw.bsky.social · 28/04/2025

2. Dermotypes are highly coordinated across sites. For some sites, we can predict the dermotype just by knowing dermotype of another site. Left and right sides of the body are also highly correlated, suggesting that individual intrinsic factors strongly shape the skin microbiome.

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Reposted by Chengchen Li (Cherry)

Niranjan Nagarajan @niranjantw.bsky.social · 28/04/2025

3. Microbes behave very differently across dermotypes in terms of who they co-occur with! We can confirm this with culture-based experiments that show that oxygen gradients and nutrient availability likely shape why we see distinct dermotypes in various individuals. @atVidu

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Reposted by Chengchen Li (Cherry)

Niranjan Nagarajan @niranjantw.bsky.social · 28/04/2025

4. Dermotypes exhibit distinct associations w/ host, where ethnicity and gender play a role in some cases, while others are linked to skincare behaviors. Skin sensitivity, itch and eczema may be affected by dermotype function, highlighting utility for patient stratification & therapeutics

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Reposted by Chengchen Li (Cherry)

Niranjan Nagarajan @niranjantw.bsky.social · 28/04/2025

5. Exciting days ahead as we try to decipher the contributions of diverse factors that shape skin microbiome dermotypes, and in turn their influence on skin health! @cherrychengchenli.bsky.social

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Chengchen Li (Cherry) @cherrychengchenli.bsky.social · 28/04/2025

Which skin microbiome type do you have 🤔 Check out our exciting work from the Asian Skin Microbiome Program offering new insights of skin microbiome population heterogeneity👇 #skinmicrobiome #microbiomescience

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