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Cereda Lab

@ceredalab.bsky.social
2.2K followers 284 following 41 posts

R2Nito Lab - RNA Regulatory Networks in Translational Oncology @ifomresearch.bsky.social and @LaStatale + @iigm-turin.bsky.social | RNA oncology www.ceredalab.com

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Reposted by Cereda Lab
Cereda Lab @ceredalab.bsky.social · 05/10/2026
Our paper on RNAmotifs 2.0 is out in @bmcbiol.springernature.com 🌟 How to prioritize which RNA-binding protein is behind the splicing changes in your RNA-seq data? RNAmotifs 2.0 links multivalent RNA motifs to candidate regulators. 🧵 link.springer.com/article/10.1...
link.springer.com
RNAmotifs 2.0: a framework for inferring multivalent RNA motifs and their candidate regulators of splicing - BMC Biology
Background Alternative splicing expands proteomic diversity and is shaped by RNA‑binding proteins (RBPs) that bind to multivalent RNA motifs. Yet connecting cis-acting motifs to their candidate trans-...
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Cereda Lab @ceredalab.bsky.social · 05/10/2026
@matteocereda.bsky.social @mchiaragrieco.bsky.social @tommasobecchi.bsky.social @iigm-turin.bsky.social @ifomresearch.bsky.social @AIRC
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Cereda Lab @ceredalab.bsky.social · 05/10/2026
6/🧵 Motifs matter: you can now move from catalogs of motifs and binding maps to interpretable regulatory models. 🔎 Explore: ceredalab.com/page-rnamotifs .html 📄 Read: doi.org/10.1186/s12915 -026-02745-x 💻 Use: github.com/matteocereda/R
ceredalab.com
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Cereda Lab @ceredalab.bsky.social · 05/10/2026
5/🧵 An independent HNRNPK knockdown in PC3 cells further supported the transferability of inferred motif‑protein relationships across cellular contexts despite minimal overlap between exon sets.
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Cereda Lab @ceredalab.bsky.social · 05/10/2026
4/🧵 Across ENCODE perturbation datasets, RNAmotifs 2.0 consistently prioritized RBPs associated with exon repression and activation.
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Cereda Lab @ceredalab.bsky.social · 05/10/2026
3/🧵 RNAmotifs 2.0 links multivalent cis-regulatory RNA motifs to candidate trans-acting RBPs by integrating sequence enrichment, eCLIP binding profiles and splicing responses to RBP depletion in an interpretable statistical model.
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Cereda Lab @ceredalab.bsky.social · 05/10/2026
2/🧵 Alternative splicing is shaped by RNA-binding proteins that recognize multivalent RNA motifs. But how can we decode RNA regulatory networks shaped by multivalency?
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Cereda Lab @ceredalab.bsky.social · 05/10/2026
Our paper on RNAmotifs 2.0 is out in @bmcbiol.springernature.com 🌟 How to prioritize which RNA-binding protein is behind the splicing changes in your RNA-seq data? RNAmotifs 2.0 links multivalent RNA motifs to candidate regulators. 🧵 link.springer.com/article/10.1...
link.springer.com
RNAmotifs 2.0: a framework for inferring multivalent RNA motifs and their candidate regulators of splicing - BMC Biology
Background Alternative splicing expands proteomic diversity and is shaped by RNA‑binding proteins (RBPs) that bind to multivalent RNA motifs. Yet connecting cis-acting motifs to their candidate trans-...
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Cereda Lab @ceredalab.bsky.social · 01/02/2026
@matteocereda.bsky.social @mchiaragrieco.bsky.social @tommasobecchi.bsky.social @iigm-turin.bsky.social @ifomresearch.bsky.social
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Cereda Lab @ceredalab.bsky.social · 01/02/2026
How to link multivalent #RNAmotifs to their cognate #RBP regulator from #RNA-seq data only? Easy: RNAMaRs!💥 Relying on RBP binding principles and optimized #motif discovery RNAMaRs infers biologically interpretable motif-RBP associations. Check our new preprint here 👉 www.biorxiv.org/content/10.6...
biorxiv.org
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Cereda Lab @ceredalab.bsky.social · 05/12/2025
@iigm-turin.bsky.social @matteocereda.bsky.social @ifomresearch.bsky.social
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Cereda Lab @ceredalab.bsky.social · 05/12/2025
📢 How does #epigenetics fuel #chromosome #instability in #cancer? Together with @IlioVitale and @deadoc80.bsky.social, we highlighted two recent papers from @NatGen and @CD_AACR in our newly published @cp-trendscancer.bsky.social Spotlight! Check it out here 👉 www.sciencedirect.com/science/arti...
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Reposted by Cereda Lab
Mariachiara Grieco @mchiaragrieco.bsky.social · 29/06/2025
Had a blast at the @pezcoller Symposium in Trento! Happy to receive the Travel Grant Award and be awarded by Nobel Laureate William Kaelin🌟 Top-notch speakers, amazing science and connections. Deep thanks to @ceredalab.bsky.social and @IIGMufficiale, and @matteocereda.bsky.social for his mentorship🚀
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Reposted by Cereda Lab
Mariachiara Grieco @mchiaragrieco.bsky.social · 29/06/2025
Amazing days at #EACR2025! Inspiring science, excellent sessions, and such an incredible #cancerResearch community✨ huge thanks to @ceredalab.bsky.social and @matteocereda.bsky.social for the constant support and @IIGM . Also super happy that @AIRC_it stopped by my poster 🌟 @helloeacr.bsky.social
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Cereda Lab @ceredalab.bsky.social · 25/05/2025
@matteocereda.bsky.social
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Cereda Lab @ceredalab.bsky.social · 25/05/2025
How soon is now? Very. Great two-day conference at @fpoirccs @IIGM to embrace the latest advancements in #OvarianCancer research and clinical practice
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Reposted by Cereda Lab
Mariachiara Grieco @mchiaragrieco.bsky.social · 09/05/2025
Had a brilliant morning for a great hands-on session of Lego Serious Play with @ceredalab.bsky.social at #FaciliDay 🌟🌟 exploring how creativity can unlock new spaces of communicating and collaborating
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Reposted by Cereda Lab
Mariachiara Grieco @mchiaragrieco.bsky.social · 09/05/2025
Happy to partecipate in the @embo.org workshop #chromoploidy25 in Stresa! Have been 4 days packed of interesting talks, valuable suggestions and new connections ⭐️ thanks to @matteocereda.bsky.social and the whole @ceredalab.bsky.social
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Cereda Lab @ceredalab.bsky.social · 24/02/2025
Kudos to @raffaella.ergasti for presenting our ongoing work on #transcriptional #signatures underlying high-grade serous #ovariancancer subtypes in collaboration with Gemelli Hospital at @ESGO_society in Rome 🌟🌟🌟 well done 🙌🙌 #esgo2025
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Cereda Lab @ceredalab.bsky.social · 30/01/2025
Celebrating Chinese New Year 🧧🐍✨ Excited for the #YearOfTheSnake symbolizing enthusiasm and energy 🔥 Lily and Stephanie’s homemade dumplings were a hit 🥟🌟
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Reposted by Cereda Lab
Cereda Lab @ceredalab.bsky.social · 18/11/2024
🚨 Thrilled to share also here this exciting and collaborative research on #KRAS G12C adaptive resistance and therapy recently out in @NatureComms W/ @AmbrogioLab @SantamariaLab @BiagioRicciutiMD ➡️ www.nature.com/articles/s41... @oncoalert.bsky.social l @natureportfolio.bsky.social
nature.com
RAS-ON inhibition overcomes clinical resistance to KRAS G12C-OFF covalent blockade - Nature Communications
KRAS G12C mutant selective inhibitors targeting inactive state have been approved for use in non-small cell lung cancer (NSCLC). Here, using models derived from a patient with NSCLC who progressed on ...
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Cereda Lab @ceredalab.bsky.social · 28/11/2024
Sure , added
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Cereda Lab @ceredalab.bsky.social · 28/11/2024
Sure, added!
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Cereda Lab @ceredalab.bsky.social · 26/11/2024
Cool, sure! Added
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Cereda Lab @ceredalab.bsky.social · 26/11/2024
Sure, added!
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Cereda Lab @ceredalab.bsky.social · 25/11/2024
Added, enjoy!
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Cereda Lab @ceredalab.bsky.social · 25/11/2024
Sure , added!
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Cereda Lab @ceredalab.bsky.social · 25/11/2024
Added, thanks!
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Cereda Lab @ceredalab.bsky.social · 25/11/2024
Added, thanks!
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Cereda Lab @ceredalab.bsky.social · 25/11/2024
Sure, added!
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Cereda Lab @ceredalab.bsky.social · 24/11/2024
Added, thanks for your interest!
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Cereda Lab @ceredalab.bsky.social · 24/11/2024
Added! Thanks for your interest in joining it
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Cereda Lab @ceredalab.bsky.social · 23/11/2024
would love to be added, thanks!
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Reposted by Cereda Lab
Mariachiara Grieco @mchiaragrieco.bsky.social · 19/11/2024
Poster session is up at #semmretreat24 ⭐️ presenting ongoing PhD project focused on how #RNAprocessing is altered upon genomic instability in #colorectal cancers Really excited to present it to my PhD peers✨✨ Thanks to @semm_it and @ceredalab.bsky.social
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Cereda Lab @ceredalab.bsky.social · 18/11/2024
🚀🚀🚀🚀🚀
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Cereda Lab @ceredalab.bsky.social · 18/11/2024
🚨 Thrilled to share also here this exciting and collaborative research on #KRAS G12C adaptive resistance and therapy recently out in @NatureComms W/ @AmbrogioLab @SantamariaLab @BiagioRicciutiMD ➡️ www.nature.com/articles/s41... @oncoalert.bsky.social l @natureportfolio.bsky.social
nature.com
RAS-ON inhibition overcomes clinical resistance to KRAS G12C-OFF covalent blockade - Nature Communications
KRAS G12C mutant selective inhibitors targeting inactive state have been approved for use in non-small cell lung cancer (NSCLC). Here, using models derived from a patient with NSCLC who progressed on ...
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Cereda Lab @ceredalab.bsky.social · 17/11/2024
Would love to join this, thanks!
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Reposted by Cereda Lab
Danny IncaRNAto @incarnatolab.bsky.social · 15/11/2024
Fellow #RNA lovers, please repost 🙏: 2 ERC-funded Post-doc positions are available in our lab to investigate #RNA structural ensemble and their dynamics in living cells. Application link: t.co/pYJ3H3j705
t.co
https://www.rug.nl/about-ug/work-with-us/job-opportunities/?details=00347-02S000B06P
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Reposted by Cereda Lab
Johanna Joyce @johannajoyce.bsky.social · 17/11/2024
Here's the #Cancer #Research #2 starter pack 🤩 Researchers, oncologists, patient advocates & more -working across all aspects of cancer research and treatment 🧪🔬⚕️ I also tried to give some exposure to #PhD #students & #postdocs - randomly picked from followers of me or my lab! go.bsky.app/6EcjWNA
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Cereda Lab @ceredalab.bsky.social · 17/11/2024
Join! go.bsky.app/51oKcPM
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Cereda Lab @ceredalab.bsky.social · 17/11/2024
Would love to join the starter pack, thanks!
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Cereda Lab @ceredalab.bsky.social · 17/11/2024
Would love to be added, thanks!
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Cereda Lab @ceredalab.bsky.social · 17/11/2024
Would love to be added, thanks!
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Cereda Lab @ceredalab.bsky.social · 17/11/2024
Would love to be added, thanks!
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Reposted by Cereda Lab
Stephen Turner @stephenturner.us · 16/11/2024
Bluesky for Science Starter packs for genomics, bioinformatics, #Rstats, Nextflow. Moderation lists. Feeds. Let's rebuild the old scitwitter community and keep this place nice blog.stephenturner.us/p/bluesky-fo... 🧬🖥️🧪
blog.stephenturner.us
Bluesky for Science
Bluesky starter packs for genomics, bioinformatics, R, and Nextflow
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Cereda Lab @ceredalab.bsky.social · 17/11/2024
Would love to be added to Bioinformatics+Genomics, thanks!
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Cereda Lab @ceredalab.bsky.social · 17/11/2024
Would love to be added, thanks!
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Cereda Lab @ceredalab.bsky.social · 17/11/2024
Would love to be added, thanks!
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Reposted by Cereda Lab
Andreas Moor @andreasmoor.bsky.social · 16/11/2024
So many nice starter packs.. I couldn't find one related to spatial biology yet, so I started one 🧬🔬! Here's who I’ve included so far—let me know if you'd like to be added or suggest other must-follow accounts! #SpatialBiology go.bsky.app/SU34ELC
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Cereda Lab @ceredalab.bsky.social · 17/11/2024
would love to be added , thanks!
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