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Carthera

@carthera.bsky.social
95 followers 149 following 104 posts

#MedTech #startup developing innovative therapeutic ultrasound-based medical devices to treat brain disorders 🧠 🖥️ Website: carthera.eu 🥼 Glioblastoma trial: sonobird.eu #Oncology #Neurology #Glioblastoma #Alzheimers #SonoCloud

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Carthera @carthera.bsky.social · 02/10/2025
📢 Update: this account will no longer be active. Thank you for following our journey here. Moving forward, we’ll continue to share all corporate and clinical news on our LinkedIn page 👉 www.linkedin.com/company/carthera/ We look forward to staying connected with you there!
linkedin.com
Carthera | LinkedIn
Carthera | 6,995 followers on LinkedIn. Advanced Brain Therapy | Carthera® is a clinical-stage medtech company focused on developing innovative ultrasound-based medical devices to treat a wide range o...
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Carthera @carthera.bsky.social · 26/09/2025
Breaking Barriers: How Carthera’s SonoCloud Offers New Perspectives to Brain Cancer Patients 🧠 The American Brain Tumor Association has published an informative article for patients about our SonoCloud technology and how it's being used to treat glioblastoma. www.abta.org/mindmatters/...
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Carthera @carthera.bsky.social · 24/09/2025
🗓️ Meet the Carthera team from next week for the latest insights into our Phase III study evaluating SonoCloud 9 for #glioblastoma 🇦🇹 #EANS2025 Vienna, 5-9 [Booth 8] 🇺🇸 #CNS2025 LA, 11-15 [Booth 588] 🇨🇿 #EANO2025 Prague, 16-19 [Booth 9] 💬 Drop by our booths or send us a DM to arrange a meeting
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Carthera @carthera.bsky.social · 18/09/2025
Finding a #braintumor clinical trial can be overwhelming. That’s why Carthera is proud to sponsor Ancora.ai’s Brain Tumor Trial Finder — a tool that helps patients and families quickly navigate options and access clinical trials worldwide 🌍www.ancora.ai/en?condition...ai
ancora.ai
Ancora - Find Cancer Clinical Trials
Ancora is a search tool that enables cancer patients to find relevant clinical trials in minutes. Radiopharmaceutical trial finder, nuclear medicine.
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Carthera @carthera.bsky.social · 09/09/2025
🗓️ Meet the Carthera team in October for the latest insights into our Phase III study evaluating SonoCloud‑9 for #glioblastoma 🇦🇹 #EANS2025 Vienna, 5-9 [Booth 8] 🇺🇸 #CNS2025 LA, 11-15 [Booth 588] 🇨🇿 #EANO2025 Prague, 16-19 💬 Drop by our booths or send us a DM to arrange a meeting
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Carthera @carthera.bsky.social · 05/09/2025
GLIOBLASTOMA TRIAL UPDATE 📣 Sonobird is now active in Denmark! 🇩🇰 Two weeks ago, the team at University of Copenhagen included the first Danish patient. To learn more about the trial including active recruitment centres 👇 sonobird.eu #Glioblastoma #ClinicalTrial #NeuroOncology
sonobird.eu
SONOBIRD: a pivotal trial in recurrent glioblastoma
SONOBIRD is a randomized, open-label, multicentric, two-arm pivotal trial comparing treatment with SonoCloud-9 combined with carboplatin versus standard of care lomustine or temozolomide in patients u...
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Carthera @carthera.bsky.social · 02/09/2025
🎙️ Our CSO Michael Canney was recently featured on the Med Tech Gurus podcast, where he dives into how our SonoCloud technology works and its potential to revolutionize glioblastoma care www.youtube.com/watch?v=3kUF... #NeuroOncology #ClinicalTrials #Glioblastoma #MedTech
youtube.com
Breaking Barriers
YouTube video by Med Tech Gurus
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Carthera @carthera.bsky.social · 28/08/2025
Summer Review: Transforming Glioblastoma Treatment 🧠 🙏 Thank you to our hardworking team, supportive partners, dedicated researchers and brave patients for supporting our mission of providing a new treatment for #glioblastoma Interviews & Podcast access 👉 linktr.ee/carthera
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Carthera @carthera.bsky.social · 20/08/2025
📣 Our CSO Michael Canney discussed our innovative approach to treating recurrent #glioblastoma on the Brain Wellness podcast. He explains how we use therapeutic ultrasound to enhance chemotherapy delivery to the brain. www.youtube.com/watch?v=KcUu... #MedTech #BrainCancer #ClinicalTrials
youtube.com
Brain Wellness - episode 145: Using ultrasound to treat glioblastoma with Michael Canney
YouTube video by Brain Wellness NP
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Carthera @carthera.bsky.social · 13/08/2025
📣 Our CSO, Michael Canney talks all things Sonobird on the Bindwaves podcast. Learn about SonoCloud-9, our ultrasound implant that disrupts the blood-brain barrier to enhance the delivery of therapeutic drugs. www.youtube.com/watch?v=B2_D... #Glioblastoma #BrainCancer #Oncology #ClinicalTrials
youtube.com
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Carthera @carthera.bsky.social · 06/08/2025
This trial involves 40+ clinical sites in the EU & US, evaluating our SonoCloud device to temporarily open the blood-brain barrier and enhance chemotherapy delivery for recurrent #glioblastoma patients Learn more about the trial and clinical sites in Italy👇 sonobird.eu #clinicaltrials #medtech
sonobird.eu
SONOBIRD: a pivotal trial in recurrent glioblastoma
SONOBIRD is a randomized, open-label, multicentric, two-arm pivotal trial comparing treatment with SonoCloud-9 combined with carboplatin versus standard of care lomustine or temozolomide in patients u...
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Carthera @carthera.bsky.social · 06/08/2025
📣 We’re thrilled to announce that our phase 3 trial for recurrent #glioblastoma has launched in Italy with the first patient enrolled in Bologna 🇮🇹 Prof. Giuseppe Lombardi, Italy’s referring investigator and site lead in Padua recently spoke about the trial. Watch the interview👇 bit.ly/4msq3gX
bit.ly
Padova, un "device" a ultrasuoni per combattere il glioblastoma
Affidato allo Iov il coordinamento di un innovativo progetto internazionale per rendere molto più efficaci le terapie per contrastare questo aggressivo tumore cerebrale
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Carthera @carthera.bsky.social · 01/08/2025
A new study has identified genes responsible for the spread of #glioblastoma, opening up new avenues for treatment. This breakthrough could pave the way for more effective therapies and improved patient outcomes. Learn more👇 www.insideprecisionmedicine.com/topics/oncol... #BrainTumor #Oncology
insideprecisionmedicine.com
Genes Causing Spread of Glioblastoma Open Treatment Avenues
New research shows how glioblastoma cells infiltrate the brain and which key genes drive the invasion, paving the way to new treatments.
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Carthera @carthera.bsky.social · 24/07/2025
🧠 Purdue University Researchers Develop a Novel Human Brain Model to Study Alzheimer’s Disease vet.purdue.edu/news/purdue-... #Alzheimers
vet.purdue.edu
Purdue Researchers Develop a Novel Human Brain Model to Study Alzheimer's Disease
Purdue University College of Veterinary Medicine researchers are taking an innovative approach to studying Alzheimer’s disease. Dr. Ranjie Xu, an assistant professor in the Department of Basic Medical...
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Carthera @carthera.bsky.social · 16/07/2025
🧠 On #GlioblastomaDay, we stand with the global call for better awareness, research & treatments. Only four FDA-approved drugs & one device exist, we are working to change this through our SonoCloud system. Read Lynn's story - a patient in our Sonobird trial👇 www.med.unc.edu/neurosurgery...
med.unc.edu
Glioblastoma Patient Joins the Sonobird Clinical Trial at UNC Health | Department of Neurosurgery
Lynn lives an active lifestyle as an owner of her own luxury traveling tours business. But when she got back from a corporate cruise in November of 2023, she started to feel sick every day. Lynn was q...
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Carthera @carthera.bsky.social · 09/07/2025
🔊 New podcast! Our CSO Dr. Michael Canney joins “Michael and Mom” to talk about the BBB, glioblastoma, and how SonoCloud is changing drug delivery to the brain. Listen here: www.youtube.com/watch?v=lvRU... #Glioblastoma #Oncology #ClinicalTrial
youtube.com
Michael & Mom Talk Glioblastoma Trial: Episode 63, Using Ultrasound to Break the Blood Brain Barrier
YouTube video by Michael and Mom Inspire
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Carthera @carthera.bsky.social · 01/07/2025
Exciting news! Our SonoCloud is among the first devices to receive a positive opinion from the EMA expert panel for Orphan Medical Device status, targeting recurrent glioblastoma. A big step toward CE marking! ala.associates/regulatory/c... #Glioblastoma #Oncology #MedTech #NeuroOncology
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Carthera @carthera.bsky.social · 26/06/2025
Our CSO was recently featured on The Childhood Cancer Perspective Tune in to learn more about our vision and the impactful work being done at Carthera www.youtube.com/watch?v=VsCq... #BrainCancerResearch #Glioblastoma #MedicalBreakthroughs
youtube.com
S5:E78 Interview with Dr. Michael Canney
YouTube video by Battlecorn Care Packages
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Carthera @carthera.bsky.social · 13/06/2025
Our CSO was recently featured on the PsyDactic podcast! 📲 Want to gain insights into the future of ultrasound technology and the work being done at Carthera? Listen to the full episode here: psydactic.buzzsprout.com/1909786/epis... #Ultrasound #Research #Podcast
psydactic.buzzsprout.com
Therapeutic Ultrasound with Dr. Michael Canney PhD - PsyDactic
This episode includes a fascinating interview with a researcher in ultrasound, Dr. Michael Canney who is an acoustics researcher the chief scientific officer at a French company named Carthera (https:...
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Carthera @carthera.bsky.social · 05/06/2025
Le Pr. Olivier Chinot de @aphm-chu-marseille.bsky.social était ce matin sur @bfmmarseille.bsky.social 📽️ Découvrez comment notre technologie innovante est en train de changer la donne dans la lutte contre le cancer du cerveau www.bfmtv.com/marseille/re... #glioblastome #Santé #RechercheMédicale
bfmtv.com
Marseille: une solution pour traiter le cancer du cerveau
VIDÉO - Le professeur Olivier Chinot, neuro-oncologue à l'APHM, présente un essai clinique innovant pour traiter le glioblastome, un cancer du cerveau.
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Carthera @carthera.bsky.social · 04/06/2025
Our CSO will be onsite to present a poster about the Sonobird trial for rGBM during the International Society for Therapeutic Ultrasound event in Banff, Alberta, Canada from 21-24 June, 2025! Find out more about the event and how you can register here👇 istu.org #ISTU2025 #focusedultrasound
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Carthera @carthera.bsky.social · 29/05/2025
🎧 LISTEN IN: Sound waves meet brain science. In this podcast, Carthera shares how we use ultrasound to tackle brain tumors and neurodegenerative diseases. Learn about our SONOBIRD pivotal clinical trial; changing how we fight #glioblastoma 👉 sonobird.eu podcasts.apple.com/us/podcast/e...
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Carthera @carthera.bsky.social · 27/05/2025
How do we overcome the blood-brain barrier ? 🧠 Despite advancements in #glioblastoma treatment, the BBB remains a critical obstacle. In this Cureus article, part of Springer Nature, the authors suggest that one of the most promising uses of FUS is BBB disruption. www.cureus.com/articles/353...
cureus.com
Overcoming the Blood-Brain Barrier: Focused Ultrasound in Glioblastoma Treatment
Despite recent advancements in neuro-oncology, glioblastoma remains one of the cancers with the poorest prognosis. Tumor recurrence and progression are driven by tumor stem cells and a high mutational...
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Carthera @carthera.bsky.social · 20/05/2025
It's #ClinicalTrialsDay! Clinical trials are essential to prove the safety and efficacy of our SonoCloud system in order to improve the treatment of brain diseases such as #Glioblastoma and neurodegenerative diseases.
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Carthera @carthera.bsky.social · 12/05/2025
Don't miss this article from NewYork-Presbyterian and @columbiacancer.bsky.social spotlighting our SONOBIRD trial Huge thanks to Dr. Brian Gill and the team of researchers and clinicians driving this innovation www.nyp.org/advances/art... #Glioblastoma #BrainTumor #ClinicalTrials
nyp.org
Disrupting the Blood-Brain Barrier to Improve Glioblastoma Treatment | Spotlight | Advances in Neurology and Oncology | NewYork-Presbyterian
NewYork-Presbyterian neurosurgeon Dr. Brian Gill describes the SONOBIRD trial, which tests a new implantable ultrasound device that may improve drug delivery to the brain to treat glioblastoma.
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Carthera @carthera.bsky.social · 05/05/2025
This weekend, our Chief Scientific Officer spoke with @foxnews.com.web.brid.gy to break down what people should know about glioblastoma following Michael Bolton's diagnosis, and how Carthera is advancing progress toward new breakthroughs in treatment delivery. Full article: bit.ly/42ZTdM9
bit.ly
Michael Bolton had strange symptoms before brain cancer diagnosis: ‘Something’s wrong’
A Grammy-winning singer who was diagnosed in December 2023 with glioblastoma—the most aggressive and rapidly progressing type of brain cancer—began showing signs that something was wrong the previous ...
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Carthera @carthera.bsky.social · 29/04/2025
Our innovative SonoCloud technology has been used to treat the first glioblastoma patient in Florida! A huge thank you to @moffittnews.bsky.social for their dedication and expertise in making this possible. Want to learn more ? www.moffitt.org/endeavor/arc... #Glioblastoma #ClinicalTrials
moffitt.org
Moffitt Treats First Glioblastoma Patient in Florida Using New Technology
Carthera’s Sonocloud-9 could eliminate challenges presented by the blood-brain barrier
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Carthera @carthera.bsky.social · 24/04/2025
📢 Tomorrow our team will be at the American Association of Neurological Surgeons' Annual Meeting! Visit us at Booth 1352 to learn about Sonobird, our pivotal trial in recurrent #glioblastoma🧠 annualmeeting.aans.org #AANS2025 #glioblastoma #neurosurgery
annualmeeting.aans.org
Home - AANS Annual Meeting 2025
Save the Date: ANNS Annual Meeting! The premier event for neurosurgeons and neurosurgical medical professionals in Boston, April 25-28, 2025.
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Carthera @carthera.bsky.social · 22/04/2025
📣 CLINICAL TRIAL MILESTONE We are thrilled to share that we have recruited 100 patients to our SONOBIRD pivotal trial across the EU and US in the world's largest ever trial performed on glioblastoma patients using ultrasound-based blood-brain barrier opening 🧠 ala.associates/clinical/car...
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Carthera @carthera.bsky.social · 17/04/2025
🥼University of Minnesota researchers are developing a cell therapy that would combat Alzheimer’s disease using strategies used in blood cancer treatment 👉https://bit.ly/42IJb2a #Alzheimers #Neurology #CellTherapy
mndaily.com
UMN researchers developing cell therapy to combat Alzheimer’s disease
Researchers from the University of Minnesota are developing a cell therapy that would combat Alzheimer’s disease using strategies used in blood cancer treatment, according to a press release. The cell...
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Carthera @carthera.bsky.social · 09/04/2025
📢 In 2 weeks our clinical team will be in Boston for the American Association of Neurological Surgeons' Annual Meeting! Drop by Booth 1352 to learn insights into Sonobird, our pivotal trial in recurrent glioblastoma 🧠 Event details👇 annualmeeting.aans.org #AANS2025 #glioblastoma #neurosurgery
annualmeeting.aans.org
Home - AANS Annual Meeting 2025
Save the Date: ANNS Annual Meeting! The premier event for neurosurgeons and neurosurgical medical professionals in Boston, April 25-28, 2025.
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Carthera @carthera.bsky.social · 03/04/2025
📺 Learn how our SonoCloud system works to disrupt the blood-brain barrier to enhance the delivery of therapeutic agents to brain tissues 🧠 www.youtube.com/watch?v=HhcO... #SonoCloud #BBB #neurology #medtech #therapeuticultrasound
youtube.com
Carthera's SonoCloud-9 System
YouTube video by Carthera
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Carthera @carthera.bsky.social · 01/04/2025
The Oxford Drug Discovery Institute is using artificial intelligence and ‘knowledge graphs’ to sift through vast amounts of biomedical data, potentially leading to faster treatments - @wsj.com www.wsj.com/articles/ai-... #Alzheimers #AI #Neurology
wsj.com
AI-Powered Databases Boost the Alzheimer’s Drug Discovery Process
Researchers studying Alzheimer’s disease are using artificial intelligence-powered databases to accelerate the drug discovery process by making it easier to sift through vast amounts of biomedical dat...
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Carthera @carthera.bsky.social · 28/03/2025
📢 Next month our clinical team will be in Boston for the American Association of Neurological Surgeons' Annual Meeting! Come at Booth 1352 to learn insights into Sonobird, our pivotal trial in recurrent glioblastoma🧠 Event details👇 annualmeeting.aans.org #AANS2025 #glioblastoma #neurosurgery
annualmeeting.aans.org
Home - AANS Annual Meeting 2025
Save the Date: ANNS Annual Meeting! The premier event for neurosurgeons and neurosurgical medical professionals in Boston, April 25-28, 2025.
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Carthera @carthera.bsky.social · 19/03/2025
@cambridgeuni.bsky.social PhD student Sarah Nicholls talks about her research on the protein tau and the role it might play in #Alzheimers Disease www.gatescambridge.org/about/news/e... #tau #neurology #neurodegenerative
gatescambridge.org
Exploring the role of tau in Alzheimer’s - Gates Cambridge
Scholar-Elect Sarah Nicholls talks about her research on the protein tau and the role it might play in Alzheimer's Disease
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Carthera @carthera.bsky.social · 13/03/2025
🥼 Researchers at UT Southwestern have found that transcranial direct current stimulation temporarily improved some patients’ cognitive skills in a preliminary trial www.utsouthwestern.edu/newsroom/art... #Alzheimers #Neurostimulation #Neurology
utsouthwestern.edu
Neurostimulation shows promise as potential Alzheimer’s treatment
Repeated sessions of electrical stimulation to brain networks associated with memory improved verbal learning in some Alzheimer’s disease patients for up to eight weeks in a preliminary trial led by U...
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Carthera @carthera.bsky.social · 11/03/2025
🗞️ Accelerating the search for new #glioblastoma treatments Interesting read on @cancerresearchuk.org by @oh-henry.bsky.social news.cancerresearchuk.org/2025/03/04/a...
news.cancerresearchuk.org
Accelerating the search for new glioblastoma treatments - Cancer Research UK - Cancer News
Henry Scowcroft looks at a pioneering new clinical platform trial set to offer more options to UK glioblastoma patients and kick-start progress
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Carthera @carthera.bsky.social · 05/03/2025
Want to learn more about our Sonobird trial? Watch this webinar with Principal Investigator, Dr Adam Sonabend where he talks about how our SonoCloud device is being used to treat #glioblastoma👇 🔗 www.youtube.com/watch?v=P66x... #oncology #medtech
youtube.com
Using Ultrasound Technology To Open The Blood Brain Barrier
YouTube video by Al Musella
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Carthera @carthera.bsky.social · 27/02/2025
🧠 Researchers have uncovered how microbubbles open the blood-brain barrier Read the full article👇 www.technologynetworks.com/tn/news/how-... #BBB #DrugDelivery
technologynetworks.com
How Microbubbles Enable Targeted Drug Delivery
ETH Zurich researchers have revealed how ultrasound-activated microbubbles create liquid jets that pierce blood vessel walls, allowing drugs to enter the brain. Their findings clarify the mechanisms b...
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Carthera @carthera.bsky.social · 26/02/2025
📣GLIOBLASTOMA TRIAL ALERT! Our SONOBIRD trial is now open in the US & Europe! Today’s spotlight: Dallas🇺🇸 Dr Toral Patel and her team will be supporting patients at University of Texas Southwestern Medical Center🏥 Trial details👇 sonobird.eu #glioblastoma #oncology #clinicaltrial #medtech
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Carthera @carthera.bsky.social · 26/02/2025
🗞️According to an article published in @nature.com repurposed drugs provide a rich source of potential therapies for Alzheimer’s disease (AD) and other neurodegenerative disorders (NDD) Read the full article👇 www.nature.com/articles/s41... #Alzheimers #Neurodegenerative #Neurology
nature.com
Drug repurposing for Alzheimer’s disease and other neurodegenerative disorders - Nature Communications
Repurposed drugs provide a rich source of potential therapies for Alzheimer’s disease (AD) and other neurodegenerative disorders (NDD). In this review, the authors discuss the advantages and challenge...
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Carthera @carthera.bsky.social · 25/02/2025
@neurosurgerynm.bsky.social investigators have discovered unique genetic and structural changes in endothelial cells in the brain after disrupting the blood-brain barrier in patients with recurrent #glioblastoma news.feinberg.northwestern.edu/2025/02/24/b... #Neurology #BBB
news.feinberg.northwestern.edu
Blood-Brain Barrier Disruption Reveals Genetic and Structural Changes in Neurological Diseases - News Center
Northwestern Medicine investigators have discovered unique genetic and structural changes in endothelial cells in the brain after disrupting the blood-brain barrier, which may inform new therapeutic t...
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Reposted by Carthera
Carthera @carthera.bsky.social · 11/02/2025
Want to know more about our Sonobird trial? Check out this Q&A with our CCO Carole Desseaux, CSO Michael Canney, and PI Adam Sonabend on therapeutic ultrasound for recurrent #glioblastoma 👉 www.fusfoundation.org/posts/therap...
fusfoundation.org
Therapeutic Ultrasound for Recurrent Glioblastoma: A Q&A on Carthera’s Comparative Clinical Trial
Key Points Almost a year ago in February 2024, Carthera launched its large comparative SonoCloud® Blood-Brain Barrier Opening for Recurrent Disease (SONOBIRD*) clinical trial (NCT 05902169) in Europe ...
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Reposted by Carthera
Carthera @carthera.bsky.social · 24/02/2025
📑 Our CSO Michael Canney worked with the @fusfoundation.bsky.social to produce a meeting report for EANO 2024 (@eanoassociation.bsky.social) During the event, we hosted a meeting for investigators involved in our SONOBIRD trial🥼 Read the full report👇 www.fusfoundation.org/posts/meetin...
fusfoundation.org
Meeting Report: European Association of Neuro-Oncology (EANO 2024)
Focused ultrasound presentations included both clinical and preclinical efforts to improve the treatment of brain tumors.
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Carthera @carthera.bsky.social · 24/02/2025
📣GLIOBLASTOMA TRIAL ALERT! Our SONOBIRD trial is now open in the US & Europe! Today’s spotlight: Liége🇧🇪 Pr. Pierre Frères and his team will be supporting patients at CHU de Liège🏥 Trial details👇 sonobird.eu #glioblastoma #oncology #clinicaltrial #medtech
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Carthera @carthera.bsky.social · 24/02/2025
📑 Our CSO Michael Canney worked with the @fusfoundation.bsky.social to produce a meeting report for EANO 2024 (@eanoassociation.bsky.social) During the event, we hosted a meeting for investigators involved in our SONOBIRD trial🥼 Read the full report👇 www.fusfoundation.org/posts/meetin...
fusfoundation.org
Meeting Report: European Association of Neuro-Oncology (EANO 2024)
Focused ultrasound presentations included both clinical and preclinical efforts to improve the treatment of brain tumors.
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Carthera @carthera.bsky.social · 21/02/2025
📣GLIOBLASTOMA TRIAL ALERT! Our SONOBIRD trial is now open in the US & Europe! Today’s spotlight: Denver🇺🇸 Dr Kevin Lillehei and his team will be supporting patients at University of Colorado Cancer Center🏥 Trial details👇 sonobird.eu #glioblastoma #oncology #clinicaltrial #medtech
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Carthera @carthera.bsky.social · 21/02/2025
🗞️ New research sheds light on brain inflammation in Alzheimer's www.news-medical.net/news/2025021... #Alzheimers #Research #Inflammation
news-medical.net
New research sheds light on brain inflammation in Alzheimer's
Brain inflammation, while a crucial part of the body's immune response, takes on a detrimental role in Alzheimer's disease.
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Carthera @carthera.bsky.social · 20/02/2025
📣GLIOBLASTOMA TRIAL ALERT Our SONOBIRD trial is now open in the US & Europe. Today’s spotlight: Baltimore🇺🇸 Dr. Chetan Bettegowda and his team will be supporting patients at Johns Hopkins University🏥 Trial details👇 sonobird.eu #glioblastoma #oncology #clinicaltrial #medtech
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Carthera @carthera.bsky.social · 20/02/2025
🗞️ Novel method for generating antibodies could revolutionize Alzheimer's and Parkinson's research www.news-medical.net/news/2025021... #Parkinsons #Alzheimers #research #antibodies
news-medical.net
Novel method for generating antibodies could revolutionize Alzheimer's and Parkinson's research
In diseases like Parkinson's and Alzheimer's, specific proteins misfold and clump together, forming toxic aggregates that damage brain cells.
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