The voltage-gated sodium channel NaV1.7, encoded by the SCN9A gene, is integral to nociceptor excitability and pain sensation. Multiple gain-of-function SCN9A variants have been reported to cause auto...

Spatial variations in dopamine function are linked to cognition and substance use disorders but are challenging to characterize with current methods. Because dopamine influences blood vessel dilation,...

Computational modeling reveals how uncertainty transforms harmless stimuli into perceptions of pain.

Our experiences contain countless details that may be important in the future, yet we rarely know which will matter and which won't. This uncertainty poses a difficult challenge for adaptive decision ...

In the olfactory literature there is considerable debate about how differences in olfactory receptors across different species map onto variations in perceptual acuity and performance. Although humans...