Check out this new direct #CHfunctionalization method for fused azines at #ACScentralscience : broad, metal-free and proceeding with exclusive and predictable #regiocontrol! Executed in #parallelmode for its immediate application to #drugdiscovery! 💊
pubs.acs.org/doi/10.1021/...
pubs.acs.org
Predictable C–H Functionalization of Complex <italic toggle="yes">beta</italic>-Fused Azines: A Mechanistically Bound Site-Specific Oxidation
Direct manipulation of C–H bonds enclosed in complex scaffolds persists today as an elusive disconnection when aiming for high and predictable site-selectivity. Its development toward the late-stage d...
