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Carcinogenesis_Oxford Uni Press Journal

@carcin-oxfunipress.bsky.social
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Highlighting scientific articles published in Carcinogenesis: Integrative Cancer Research - an Oxford University Press journal academic.oup.com/carcin

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Carcinogenesis_Oxford Uni Press Journal @carcin-oxfunipress.bsky.social · 17/08/2026
A new review article discusses the ATP-gated P2X7 receptor; an example where protein structure-function alteration in cancer cells favors cell survival, by conversion of the cytolytic macropore functional form to a macropore-deficient P2X7 form. doi.org/10.1093/carc...
doi.org
The P2X7 Receptor in Cancer: From Functional Receptor to Non-Functional P2X7
Abstract. The ATP-gated P2X7 receptors are abundantly expressed in immune cells, neurons, glial cells, and cancer cells. The P2X7 receptor performs distinc
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Carcinogenesis_Oxford Uni Press Journal @carcin-oxfunipress.bsky.social · 27/07/2026
Wnt/β-catenin Signaling in Hepatocellular Carcinoma: A Major Context-Dependent Contributor to Resistance to Tyrosine Kinase Inhibitors and Immune Checkpoint Inhibitors doi.org/10.1093/carc...
doi.org
Wnt/β-catenin Signaling in Hepatocellular Carcinoma: A Major Context-Dependent Contributor to Resistance to Tyrosine Kinase Inhibitors and Immune Checkpoint Inhibitors
Abstract. Hepatocellular carcinoma (HCC), accounting for nearly 90% of primary liver cancers, remains a major global health challenge due to late diagnosis
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Carcinogenesis_Oxford Uni Press Journal @carcin-oxfunipress.bsky.social · 15/07/2026
Call for Special Issue Proposals Carcinogenesis invites proposals for special issues that highlight emerging areas of cancer research and integrate discoveries across molecular, cellular, translational, and population sciences. academic.oup.com/carcin/pages...
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Call for Special Issue Proposals | Carcinogenesis | Oxford Academic
Carcinogenesis: Integrative Cancer Research Carcinogenesis invites proposals for Special Issues that highlight emerging areas of cancer research and integrate
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Carcinogenesis_Oxford Uni Press Journal @carcin-oxfunipress.bsky.social · 08/07/2026
Children with congenital heart disease undergoing cardiac catheterization show changes in circulating microRNAs linked to cancer-related pathways. These may relate to radiation exposure, but their biological significance and health implications remain unclear. doi.org/10.1093/carc...
doi.org
Exploring potential associations between low-dose cardiac catheterization radiation and blood microRNA changes in children with congenital heart disease
Abstract. The risk of cancer from medical exposure to ionizing radiation (IR) in pediatric patients—particularly those with congenital heart disease (CHD)—
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Carcinogenesis_Oxford Uni Press Journal @carcin-oxfunipress.bsky.social · 24/06/2026
Novel mechanism of carcinogenesis mediated by genome deletions induced by high-LET carbon ions doi.org/10.1093/carc...
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Carcinogenesis_Oxford Uni Press Journal @carcin-oxfunipress.bsky.social · 18/05/2026
Asbestos drives cancer-like traits via mitochondrial outer membrane permeabilization & drug-tolerant persister behaviour doi.org/10.1093/carc...
doi.org
Asbestos Exposure Induces Malignant - Like Phenotypes via Minority MOMP and Displays Characteristics of Drug-Tolerant Persister Cells
Abstract. Pleural mesothelioma (PM) usually occurs many years after asbestos fiber exposure; yet the mechanisms that convert chronic damage into malignancy
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Carcinogenesis_Oxford Uni Press Journal @carcin-oxfunipress.bsky.social · 09/04/2026
The carcinogenicity of e-cigarettes doi.org/10.1093/carc...
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Carcinogenesis_Oxford Uni Press Journal @carcin-oxfunipress.bsky.social · 19/03/2026
CarD-T: an automated pipeline for the nomination and analysis of potential human carcinogens doi.org/10.1093/carc...
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Carcinogenesis_Oxford Uni Press Journal @carcin-oxfunipress.bsky.social · 11/03/2026
In Carcinogenesis: The Tumour Microenvironment in Paediatric Rhabdomyosarcomas doi.org/10.1093/carc...
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The tumour microenvironment in paediatric rhabdomyosarcomas: a systematic review
Abstract. Rhabdomyosarcoma (RMS) is a predominantly paediatric cancer that is classified by the presence or absence of a PAX-FOXO1 fusion gene, which is as
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Carcinogenesis_Oxford Uni Press Journal @carcin-oxfunipress.bsky.social · 09/03/2026
New review article in Carcinogenesis: Functional significance of the aryl hydrocarbon receptor in oncogenic signaling pathways. doi.org/10.1093/carc...
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Carcinogenesis_Oxford Uni Press Journal @carcin-oxfunipress.bsky.social · 06/02/2026
Association between survival of patients with colon cancer and tumour infiltrating immune cell density, linked to smoking but not to alcohol consumption. In Carcinogenesis lnkd.in/gnNc9t4p
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Carcinogenesis_Oxford Uni Press Journal @carcin-oxfunipress.bsky.social · 28/01/2026
Uranium mining and lung cancer: a legacy of the nuclear age: reviews the long and ongoing story of lung cancer among miners of uranium and other ores exposed to radon and its progeny, which come from the decay of uranium. doi.org/10.1093/carc...
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Carcinogenesis_Oxford Uni Press Journal @carcin-oxfunipress.bsky.social · 28/01/2026
Genomic and transcriptomic characterization of gamma ray– and heavy ion–induced precursor B-cell lymphomas doi.org/10.1093/carc...
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Carcinogenesis_Oxford Uni Press Journal @carcin-oxfunipress.bsky.social · 17/12/2025
The passing of Philip Leslie Grover on Sep 1, 2025, aged 91, marks the loss of a foundational figure in carcinogenesis. He was the architect of the diol-epoxide theory, the bedrock of understanding how Polycyclic Aromatic Hydrocarbons bind to DNA, and cause cancer. doi.org/10.1093/carc...
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Carcinogenesis_Oxford Uni Press Journal @carcin-oxfunipress.bsky.social · 17/12/2025
Tumor-associated astrocytes inhibit tumor cell apoptosis through TNF-α-TNF receptor 2-NF-κB pathway in lung cancer brain metastasis doi.org/10.1093/carc...
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Carcinogenesis_Oxford Uni Press Journal @carcin-oxfunipress.bsky.social · 02/12/2025
Eight decades of research on the long-term health effects of radiation in atomic bomb survivors and their offspring doi.org/10.1093/carc...
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Carcinogenesis_Oxford Uni Press Journal @carcin-oxfunipress.bsky.social · 30/11/2025
Summary of radiation effects on incidence of solid cancers in the Life Span Study of atomic bomb survivors: 1958–2009 Carcinogenesis: doi.org/10.1093/carc... #cancer #incidence #atomic #bomb #radiation #Hiroshima #Nagasaki
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Carcinogenesis_Oxford Uni Press Journal @carcin-oxfunipress.bsky.social · 30/11/2025
Genomic landscape of radiation-induced somatic mutations in a normal cell doi.org/10.1093/carc...
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Carcinogenesis_Oxford Uni Press Journal @carcin-oxfunipress.bsky.social · 30/11/2025
Genomic landscape of radiation-induced somatic mutations in a normal cell doi.org/10.1093/carc...
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Carcinogenesis_Oxford Uni Press Journal @carcin-oxfunipress.bsky.social · 30/11/2025
Summary of radiation effects on incidence of solid cancers in the Life Span Study of atomic bomb survivors: 1958–2009 Carcinogenesis: doi.org/10.1093/carc... #cancer #incidence #atomic #bomb #radiation #Hiroshima #Nagasaki
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Carcinogenesis_Oxford Uni Press Journal @carcin-oxfunipress.bsky.social · 11/11/2025
Eighty years of cancer research after the atomic bombings of Hiroshima and Nagasaki doi.org/10.1093/carc...
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Carcinogenesis_Oxford Uni Press Journal @carcin-oxfunipress.bsky.social · 11/11/2025
ONLINE NOW: Special Issue on Radiation, Humanity, and Hope: 80 Years of Cancer Research Post-Hiroshima and Nagasaki academic.oup.com/carcin/issue...
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Carcinogenesis_Oxford Uni Press Journal @carcin-oxfunipress.bsky.social · 17/10/2025
Almonertinib enhances radiosensitivity in EGFR-mutant NSCLC via inhibition of EGFR signaling and DNA damage repair doi.org/10.1093/carc...
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Carcinogenesis_Oxford Uni Press Journal @carcin-oxfunipress.bsky.social · 11/09/2025
The Oncogenic Role of Aurora kinase A in Gastric Cancer: Mechanisms, Pathways and Clinical Relevance doi.org/10.1093/carc...
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Carcinogenesis_Oxford Uni Press Journal @carcin-oxfunipress.bsky.social · 09/09/2025
Epithelial Ikkβ deletion modulates immune responses and the IFNγ/CXCL9 axis during early esophageal carcinogenesis doi.org/10.1093/carc...
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Carcinogenesis_Oxford Uni Press Journal @carcin-oxfunipress.bsky.social · 08/09/2025
Nobel laureate, molecular biologist & cancer researcher, David Baltimore, died at he age of 87. shorturl.at/2t7Ya In 1975, he shared the Nobel Prize in Physiology or Medicine for discovering reverse transcriptase, challenging the view that genetic information was only transferred from DNA to RNA
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Carcinogenesis_Oxford Uni Press Journal @carcin-oxfunipress.bsky.social · 08/09/2025
Δ133-p53 isoform enhances TLR4 function to promote tumour growth doi.org/10.1093/carc...
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Carcinogenesis_Oxford Uni Press Journal @carcin-oxfunipress.bsky.social · 08/09/2025
Mammary Adipose Dysfunction in the Dual Epidemic of Obesity and Breast Cancer doi.org/10.1093/carc...
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Carcinogenesis_Oxford Uni Press Journal @carcin-oxfunipress.bsky.social · 12/08/2025
Radiation, Humanity, and Hope: 80 Years of Cancer Research Post-Hiroshima & Nagasaki In September, Carcinogenesis will publish a special issue to commemorate the 80th anniversary of the atomic bombings in Japan, & our understanding of radiation & its impact on human health academic.oup.com/carcin
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Carcinogenesis_Oxford Uni Press Journal @carcin-oxfunipress.bsky.social · 04/08/2025
Longitudinal single-cell RNA model aids prediction of EGFR-TKI resistance doi.org/10.1093/carc... The article finds that the molecular mechanisms driving EGFR-TKI resistance in lung cancer may also contribute to poorer prognosis, particularly in lung adenocarcinomas with high EGFR mutation rates.
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Carcinogenesis_Oxford Uni Press Journal @carcin-oxfunipress.bsky.social · 14/07/2025
Human papillomavirus (HPV) DNA methylation changes in HPV-associated head and neck cancer doi.org/10.1093/carc...
doi.org
Human papillomavirus (HPV) DNA methylation changes in HPV-associated head and neck cancer
This study indicates that higher levels of DNA methylation in HPV late genes are indicative of HPV-HNC risk, and it is a potential supplementary biomarker
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Carcinogenesis_Oxford Uni Press Journal @carcin-oxfunipress.bsky.social · 30/06/2025
Interplay between inflammasomes and PD-1/PD-L1 and their implications in cancer doi.org/10.1093/carc...
Interplay between inflammasomes and PD-1/PD-L1 and their implications in cancer
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Carcinogenesis_Oxford Uni Press Journal @carcin-oxfunipress.bsky.social · 19/06/2025
Urinary Metabolites in Association with Kidney Cancer Risk academic.oup.com/carcin/advan...
academic.oup.com
Urinary Metabolites in Association with Kidney Cancer Risk
Abstract. Kidney cancer incidence has increased worldwide in recent decades. While metabolomic studies have shown promise in unveiling mechanisms underlyin
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Carcinogenesis_Oxford Uni Press Journal @carcin-oxfunipress.bsky.social · 17/06/2025
The impact of reproductive factors on breast tumor and normal-adjacent tissue immune profile from menarche to menopause doi.org/10.1093/carc...
doi.org
The impact of reproductive factors on breast tumor and normal-adjacent tissue immune profile from menarche to menopause
Abstract. Reproductive factors and sex hormones are tightly linked to systemic immunity. However, no studies have examined whether reproductive factors and
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Carcinogenesis_Oxford Uni Press Journal @carcin-oxfunipress.bsky.social · 17/06/2025
Somatic p53 mutations overrepresented in lung cancer confer resistance to ROS-induced cell death doi.org/10.1093/carc...
doi.org
Somatic p53 mutations that are markedly overrepresented in lung cancer confer resistance to ROS-induced cell death
Abstract. Lung cancer is among the leading causes of cancer-related death in the U.S. Cigarette smoking remains the leading risk factor for lung cancer and
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Carcinogenesis_Oxford Uni Press Journal @carcin-oxfunipress.bsky.social · 15/05/2025
This study investigated race-specific epigenetic differences in endometrial cancer characteristics & identified subtype-associated CpG differences in genes, including genes regulating cytokine signaling, which were associated with race. doi.org/10.1093/carc...
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Carcinogenesis_Oxford Uni Press Journal @carcin-oxfunipress.bsky.social · 07/05/2025
B vitamins and colorectal cancer: exploring research hotspots and frontiers - a bibliometric and visual analysis (1994-2024) doi.org/10.1093/carc...
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Carcinogenesis_Oxford Uni Press Journal @carcin-oxfunipress.bsky.social · 24/04/2025
Genetic determinants & clinical significance of circulating and tumor-specific levels of insulin-like growth factor binding protein 7 in a Swedish breast cancer cohort: doi.org/10.1093/carc... Circulating & genetically predicted IGFBP7 levels are independent prognostic biomarkers in breast cancer.
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Carcinogenesis_Oxford Uni Press Journal @carcin-oxfunipress.bsky.social · 14/04/2025
ECM Remodeling & Malignant progression of Gallbladder Cancer doi.org/10.1093/carc... #ECM #gallbladder #cancer #bioinformatics
doi.org
NUF2 and NEK2 promote malignant progression of gallbladder cancer by remodeling the extracellular matrix
Abstract. Gallbladder cancer (GBC) ranks as the most common malignant tumor of the biliary tract, which has been characterized by late diagnosis, low excis
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Carcinogenesis_Oxford Uni Press Journal @carcin-oxfunipress.bsky.social · 09/04/2025
Genetic Susceptibility in Lung Squamous Cell Carcinoma: Data from 3890 LUSC cases and 13328 controls identified an association between 9q33.2 variants and increased risk of LUSC in smokers: doi.org/10.1093/carc... #lungcancer #LUSC #cancer #genetics #smoking
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Carcinogenesis_Oxford Uni Press Journal @carcin-oxfunipress.bsky.social · 01/04/2025
Multifaceted role of transgelin isoforms in cancer hallmarks Transgelins regulate actin filament stability & are implicated in carcinogenesis and chemoresistance. This review discusses transgelins as potential cancer biomarkers & oncogenic regulators. doi.org/10.1093/carc...
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Carcinogenesis_Oxford Uni Press Journal @carcin-oxfunipress.bsky.social · 26/03/2025
The Influence of Homologous Recombination Repair (HRR) on Temozolomide Chemosensitivity in Glioma. doi.org/10.1093/carc... This review discusses the role of HRR in temozolomide resistance in glioma, focusing on key HRR factors, including RAD51, ATM & ATR.
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Carcinogenesis_Oxford Uni Press Journal @carcin-oxfunipress.bsky.social · 25/03/2025
Amlodipine, an L-type Ca2+ channel inhibitor, regulates release of extracellular vesicles from tumor cells & emerges as a potentially promising drug to enhance immunotherapy by inhibiting the production of tumour-derived immunosuppressive exosomes doi.org/10.1093/carc...
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Carcinogenesis_Oxford Uni Press Journal @carcin-oxfunipress.bsky.social · 13/03/2025
A recent Japanese genome-wide association study identified 5 loci associated with the number of cigarettes smoked per day. This study evaluated whether these loci are associated with lung cancer risk directly or indirectly, through changing smoking behavior: doi.org/10.1093/carc...
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Theo Mantamadiotis @theo-braincan-lab.bsky.social · 16/12/2024
In Carcinogenesis: shorturl.at/6pvy6 Male mice with nestin-targeted PI3K & PTEN mutations develop tumors which resemble an aggressive form of sex cord stromal tumors. We describe the cell-of-origin, the complex histopathology & using #spatialbiology, the immune cell infiltration of this rare cancer
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Carcinogenesis_Oxford Uni Press Journal @carcin-oxfunipress.bsky.social · 12/03/2025
Germline EPHB4R91H mutation as a key player in multiple primary lung tumors doi.org/10.1093/carc...
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Carcinogenesis_Oxford Uni Press Journal @carcin-oxfunipress.bsky.social · 07/03/2025
The current landscape of therapies for hepatocellular carcinoma: doi.org/10.1093/carc... Primary liver cancer is the third leading cause of cancer-related deaths, accounting for 8.3% of deaths among all cancers. This review discusses the current treatments for early, intermediate, and advanced HCC.
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Carcinogenesis_Oxford Uni Press Journal @carcin-oxfunipress.bsky.social · 06/03/2025
Surgical stress induced tumor immune suppressive environment: doi.org/10.1093/carc...
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Carcinogenesis_Oxford Uni Press Journal @carcin-oxfunipress.bsky.social · 06/03/2025
Antibody–drug conjugates (ADCs) in breast cancer: ADCs have made an impact on the treatment of breast cancer. This review summarizes the advances in ADCs in breast cancer patients and explores the challenges and future directions in this field. doi.org/10.1093/carc...
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Anirban Maitra @anirbanmaitra.bsky.social · 23/11/2024
Dear Colleagues The journal Carcinogenesis has released a special issue on #PancreaticCancer research in honor of Perwez Hussain. It contains several open access reviews and Perwez’s last article. Please read and share. He is deeply missed. academic.oup.com/carcin/issue...
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Volume 45 Issue 11 | Carcinogenesis | Oxford Academic
Publishes original contributions on all aspects of cancer research. Subjects covered include biology, genetics and epigenetics, cancer biomarkers and molecular epidemiology, inflammation, microenviron...
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