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The Cancer Letter

@cancerletter.com
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The leading independent source for information on the issues that shape oncology since 1973. cancerletter.com

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The Cancer Letter @cancerletter.com · 14h
@cedarssinaicancer.bsky.social, @uazcancercenter.bsky.social study shows how missing pieces of Y chromosome drive cancer in men cancerletter.com/clinical-roundup/2…
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Cedars-Sinai, UA Cancer Center study shows how missing pieces of Y chromosome drive cancer in men - The Cancer Letter
Cancer cells selectively chip away gene-rich sections of the Y chromosome, triggering ripples that regulate tumor growth
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The Cancer Letter @cancerletter.com · 19h
Eric Cantor named president and CEO of PhRMA cancerletter.com/in-brief/20261002_…
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Eric Cantor named president and CEO of PhRMA - The Cancer Letter
Eric Cantor was named the next president and chief executive officer of PhRMA, effective Nov. 9. To access this subscrib
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The Cancer Letter @cancerletter.com · 20h
Nearly two years after FDA issued a final rule requiring radiologists to tell women whether their breasts are “dense” or “not dense” after a mammogram, the notification has become nearly universal. cancerletter.com/regulatory-news/20…
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The Cancer Letter @cancerletter.com · 06/10/2026
"After discussions with my family, I decided that what I wanted to do for the administration was work on cancer policy, because of what I and my family has endured," Caputo said. cancerletter.com/white-house/202610…
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The Cancer Letter @cancerletter.com · 06/10/2026
NIH introduces “Linked Discoveries,” a PubMed tool aimed at strengthening research replication, reproducibility cancerletter.com/cancer-policy/2026…
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The Cancer Letter @cancerletter.com · 06/10/2026
@cityofhope.bsky.social “plug-and-play” CAR T platform lets researchers update cells after infusion cancerletter.com/clinical-roundup/2…
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City of Hope’s “plug-and-play” CAR T platform lets researchers update cells after infusion - The Cancer Letter
Researchers from City of Hope have developed a “plug-and-play” technology that adds engineered molecules to chimeric ant
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The Cancer Letter @cancerletter.com · 06/10/2026
@ascocancer.bsky.social #GU27 remains one of the few spaces where urologic, medical, and radiation oncologists sit at the same table with diagnostic and interventional radiologists to critically evaluate the latest innovations. cancerletter.com/sponsored-article/…
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The Cancer Letter @cancerletter.com · 06/10/2026
Sanya Springfield to receive @theaacr.bsky.social Distinguished Public Service Award cancerletter.com/in-brief/20261002_…
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Sanya Springfield to receive AACR Distinguished Public Service Award - The Cancer Letter
The American Association for Cancer Research will present the 2027 AACR Distinguished Public Service Award to Sanya A. S
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The Cancer Letter @cancerletter.com · 06/10/2026
@mdanderson.bsky.social researchers found that using psilocybin as a prophylactic treatment before each cycle of chemotherapy completely prevented mechanical hypersensitivity in mice. cancerletter.com/clinical/20261002_4
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The Cancer Letter @cancerletter.com · 05/10/2026
Letai: "I hope for my Year Two, that we can really focus on executing on a lot of these initiatives that we’ve started. It does no good to start an initiative if you can’t bring it home." cancerletter.com/conversation-with-…
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The Cancer Letter @cancerletter.com · 05/10/2026
James Yu named associate director for clinical research at Dartmouth Cancer Center cancerletter.com/in-brief/20261002_…
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James Yu named associate director for clinical research at Dartmouth Cancer Center - The Cancer Letter
James B. Yu was named associate director for clinical research at Dartmouth Cancer Center. To access this subscriber-onl
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The Cancer Letter @cancerletter.com · 05/10/2026
“At some high-volume centers, appointments for MRI are booked out months in advance. I know of one breast imaging practice in the Northeast that has a 6-month wait for a screening breast MRI," Mammogen's Elise Berman said. cancerletter.com/regulatory-news/20…
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The Cancer Letter @cancerletter.com · 05/10/2026
Decipher prostate test predicts benefit from adding hormone therapy to radiation, phase III trial shows cancerletter.com/clinical-roundup/2…
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Decipher prostate test predicts benefit from adding hormone therapy to radiation, phase III trial shows - The Cancer Letter
Decipher Prostate Genomic Classifier can predict which patients are more likely to benefit from adding short-term ADT, o
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The Cancer Letter @cancerletter.com · 04/10/2026
FDA approves Ponlimsi, a biosimilar for preventing fractures in prostate and breast cancer patients cancerletter.com/drugs-and-targets/…
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FDA approves Ponlimsi, a biosimilar for preventing fractures in prostate and breast cancer patients - The Cancer Letter
FDA approved Ponlimsi (denosumab-adet) as a biosimilar to Prolia.  To access this subscriber-only content please log in
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The Cancer Letter @cancerletter.com · 04/10/2026
Federal judge blocks Trump’s second attempt at imposing $100,000 fee for H1-B visas cancerletter.com/cancer-policy/2026…
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The Cancer Letter @cancerletter.com · 04/10/2026
FDA approves Degevma, a biosimilar for cancer-related bone complications cancerletter.com/drugs-and-targets/…
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The Cancer Letter @cancerletter.com · 03/10/2026
Michael R. Caputo, a cancer survivor and a Republican political operative, was named to the President’s Cancer Panel. cancerletter.com/white-house/202610…
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The Cancer Letter @cancerletter.com · 03/10/2026
ASCO Genitourinary Cancers Symposium: Pioneering breakthroughs, optimizing patient outcomes. By the @ascocancer.bsky.social cancerletter.com/sponsored-article/…
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The Cancer Letter @cancerletter.com · 03/10/2026
Two years after FDA’s breast density notification rule, there is still no standard for follow-up So far, 38 million patients have received a dense breast notification. Now what? cancerletter.com/regulatory-news/20…
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The Cancer Letter @cancerletter.com · 03/10/2026
Trump targets HHS in $810M appropriations clawback cancerletter.com/cancer-policy/2026…
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The Cancer Letter @cancerletter.com · 03/10/2026
@mdanderson.bsky.social study suggests psilocybin may prevent chemo-induced neuropathy “Because it works in one neural system, you begin to wonder: Well, what about another?” cancerletter.com/clinical/20261002_4
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The Cancer Letter @cancerletter.com · 03/10/2026
"Last year was a year, in my view, of calming things down and starting some things up,” Letai said to The Cancer Letter cancerletter.com/conversation-with-…
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The Cancer Letter @cancerletter.com · 02/10/2026
With Year One metrics in hand, Letai is ready to “bring it home” in Year Two “I hope I don’t see any more reports of NCI cutting funding, because it just is not consistent with the facts” cancerletter.com/conversation-with-…
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The Cancer Letter @cancerletter.com · 02/10/2026
Michael Caputo appointed to President’s Cancer Panel The cancer survivor and political operative says his appointment signals Trump’s interest in cancer, survivorship cancerletter.com/white-house/202610…
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The Cancer Letter @cancerletter.com · 02/10/2026
COA survey finds high bispecific therapy adoption among community oncology practices cancerletter.com/clinical-roundup/2…
cancerletter.com
COA survey finds high bispecific therapy adoption among community oncology practices - The Cancer Letter
The Community Oncology Alliance announced results from a national survey examining how independent community oncology pr
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The Cancer Letter @cancerletter.com · 01/10/2026
Lucio Miele (LSU-LCMC Health): "The goal here is better care and better access to early diagnosis, prevention, and clinical trials for cancer patients. And collaboration is the name of the game." cancerletter.com/podcastc/20260925_1
cancerletter.com
The Directors: Two Gulf Coast cancer center directors on why NCI designation matters—and why they want it Lucio Miele and Raghu Kalluri: Science and technology have changed what an aspiring cancer center must accomplish - The Cancer Letter
What should a cancer center look like in an era of AI, genomics, complex patient populations, rising costs, and declinin
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The Cancer Letter @cancerletter.com · 01/10/2026
"A patient watching a television commercial simply hears two words: Early stage," writes Raja Flores. "Curable does not necessarily mean early. Neither does resectable." cancerletter.com/perspective/202609…
cancerletter.com
When did stage 3B lung cancer become “early stage”? - The Cancer Letter
My recent column about Merck’s television commercial for perioperative Keytruda left me with a question I could not shak
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The Cancer Letter @cancerletter.com · 01/10/2026
Colorectal Cancer Alliance (@ccalliance.bsky.social) appoints four new board members cancerletter.com/in-brief/20260925_…
cancerletter.com
Colorectal Cancer Alliance appoints four new board members - The Cancer Letter
The Colorectal Cancer Alliance has announced the appointment of four members to its board of directors. To access this s
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The Cancer Letter @cancerletter.com · 30/09/2026
Blood test could guide future treatment in Ewing sarcoma, @danafarber.bsky.social study finds cancerletter.com/clinical-roundup/2…
cancerletter.com
Blood test could guide future treatment in Ewing sarcoma, Dana-Farber study finds - The Cancer Letter
A blood test may help doctors identify which patients with Ewing sarcoma are at greater risk of relapse, according to a
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The Cancer Letter @cancerletter.com · 30/09/2026
NCI launches AI tool to help match patients to clinical trials cancerletter.com/cancer-policy/2026…
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The Cancer Letter @cancerletter.com · 30/09/2026
Erin Geddis Cummings, Bradley Zebrack receive Cancer Nation’s 2026 Ellen L. Stovall Award cancerletter.com/in-brief/20260925_…
cancerletter.com
Erin Geddis Cummings, Bradley Zebrack receive Cancer Nation’s 2026 Ellen L. Stovall Award - The Cancer Letter
Cancer Nation has awarded the following honorees with the 2026 Ellen L. Stovall Award To access this subscriber-only con
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The Cancer Letter @cancerletter.com · 30/09/2026
Though the plan has been set aside, its emergence is noteworthy, because it points to fissures between OMB and NIH. cancerletter.com/news-analysis/2026…
cancerletter.com
Trump weighs—and abandons—an executive order that would give OMB veto power over NIH grants - The Cancer Letter
The White House last week considered, but ultimately abandoned, a plan to create a panel that would review NIH grants in
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The Cancer Letter @cancerletter.com · 30/09/2026
FDA grants Priority Review to perioperative IMFINZI + enfortumab vedotin for muscle-invasive bladder cancer cancerletter.com/drugs-and-targets/…
cancerletter.com
FDA grants Priority Review to perioperative IMFINZI + enfortumab vedotin for muscle-invasive bladder cancer - The Cancer Letter
FDA has granted Priority Review for IMFINZI (durvalumab) in combination with enfortumab vedotin for the treatment of pat
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The Cancer Letter @cancerletter.com · 29/09/2026
"We must not lower the bar for approvals and introduction into the population regardless of how desperate we are for solutions,” NCI's Philip Castle said at the meeting. cancerletter.com/news-analysis/2026…
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The Cancer Letter @cancerletter.com · 29/09/2026
HHS issues direct final rule to reduce reliance on animal testing cancerletter.com/cancer-policy/2026…
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HHS issues direct final rule to reduce reliance on animal testing - The Cancer Letter
FDA has issued a direct final rule that changes the language in its regulations so that “animal testing” is no longer de
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The Cancer Letter @cancerletter.com · 29/09/2026
PDS0101 + pembrolizumab in HPV16+ R/M head and neck cancer show anti-tumor activity, VERSATILE-002 phase II study finds cancerletter.com/clinical-roundup/2…
cancerletter.com
PDS0101 + pembrolizumab in HPV16+ R/M head and neck cancer show anti-tumor activity, VERSATILE-002 phase II study finds - The Cancer Letter
PDS0101 plus pembrolizumab showed antitumor activity in ICI-naive HPV16-positive R/M HNSCC, according to the results of
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The Cancer Letter @cancerletter.com · 29/09/2026
"One of the most important advances has been our growing ability to understand the biology of each patient’s cancer and use those insights to guide treatment decisions more precisely," writes @cityofhope.bsky.social's Hope Rugo. cancerletter.com/sponsored-article/…
cancerletter.com
How biology is reshaping breast cancer care - The Cancer Letter
Breast cancer treatment has changed dramatically over the past decade. One of the most important advances has been our g
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The Cancer Letter @cancerletter.com · 29/09/2026
Rutika Mehta named director of upper GI medical oncology at NYU cancerletter.com/in-brief/20260925_…
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Rutika Mehta named director of upper GI medical oncology at NYU - The Cancer Letter
Rutika Mehta has joined NYU Langone Health’s Perlmutter Cancer Center as director of upper GI medical oncology. To acces
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The Cancer Letter @cancerletter.com · 29/09/2026
Raja Flores: "When did cancer that had already spread to lymph nodes become early-stage cancer?" cancerletter.com/perspective/202609…
cancerletter.com
When did stage 3B lung cancer become “early stage”? - The Cancer Letter
My recent column about Merck’s television commercial for perioperative Keytruda left me with a question I could not shak
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The Cancer Letter @cancerletter.com · 28/09/2026
Cancer Grand Challenges, through the Torrey Coast Foundation and Cancer Research UK, commits up to $34M to gastroesophageal cancer research cancerletter.com/funding-opportunit…
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Tagrisso increased OS in early-stage EGFR-mutated lung cancer at eight year follow-up, ADAURA phase III trial finds - The Cancer Letter
Tagrisso (osimertinib) demonstrated a sustained, clinically meaningful overall survival benefit at eight years compared
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The Cancer Letter @cancerletter.com · 28/09/2026
Raghu Kalluri (@utmbhealth.bsky.social): "People have seen how teams that play well together succeed in the end, winning a game—versus having one or two superstars. And I think that’s what comprehensive cancer care is." cancerletter.com/podcastc/20260925_1
cancerletter.com
The Directors: Two Gulf Coast cancer center directors on why NCI designation matters—and why they want it Lucio Miele and Raghu Kalluri: Science and technology have changed what an aspiring cancer center must accomplish - The Cancer Letter
What should a cancer center look like in an era of AI, genomics, complex patient populations, rising costs, and declinin
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The Cancer Letter @cancerletter.com · 28/09/2026
UNM Comprehensive Cancer Center (@unm.edu) earns NCI redesignation cancerletter.com/in-brief/20260925_…
cancerletter.com
UNM Comprehensive Cancer Center earns NCI redesignation - The Cancer Letter
The University of New Mexico Comprehensive Cancer Center has received redesignation as an NCI Comprehensive Cancer Cente
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The Cancer Letter @cancerletter.com · 28/09/2026
The White House considered, but ultimately abandoned, a plan to create a panel that would review NIH grants in an effort to weed out projects the administration regards as “woke.” cancerletter.com/news-analysis/2026…
cancerletter.com
Trump weighs—and abandons—an executive order that would give OMB veto power over NIH grants - The Cancer Letter
The White House last week considered, but ultimately abandoned, a plan to create a panel that would review NIH grants in
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The Cancer Letter @cancerletter.com · 28/09/2026
Tagrisso increased OS in early-stage EGFR-mutated lung cancer at eight year follow-up, ADAURA phase III trial finds cancerletter.com/clinical-roundup/2…
cancerletter.com
FDA approves Lyrfigtu for previously treated, unresectable, locally advanced or metastatic cholangiocarcinoma - The Cancer Letter
FDA granted approval for Lyrfigtu (lirafugratinib) as a treatment option for patients with cholangiocarcinoma with FGFR2
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The Cancer Letter @cancerletter.com · 27/09/2026
FDA approves belzutifan in combination with lenvatinib for advanced RCC with a clear cell component cancerletter.com/drugs-and-targets/…
cancerletter.com
FDA approves belzutifan in combination with lenvatinib for advanced RCC with a clear cell component - The Cancer Letter
FDA has approved belzutifan (Welireg) in combination with lenvatinib (Lenvima) for adults with advanced renal cell carci
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The Cancer Letter @cancerletter.com · 27/09/2026
Trump administration pulls 750,000 people from ACA coverage, claiming fraud cancerletter.com/cancer-policy/2026…
cancerletter.com
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The Cancer Letter @cancerletter.com · 27/09/2026
FDA approves Lyrfigtu for previously treated, unresectable, locally advanced or metastatic cholangiocarcinoma cancerletter.com/drugs-and-targets/…
cancerletter.com
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The Cancer Letter @cancerletter.com · 26/09/2026
In a long-anticipated decision, the FDA Molecular and Clinical Genetics Panel of the Medical Devices Advisory Committee voted in favor of Galleri to become the first multi-cancer detection test to receive regulatory approval. cancerletter.com/news-analysis/2026…
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The Cancer Letter @cancerletter.com · 26/09/2026
How biology is reshaping breast cancer care. @cityofhope.bsky.social's Hope S. Rugo on how our growing understanding is helping make personalized cancer care a reality cancerletter.com/sponsored-article/…
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The Cancer Letter @cancerletter.com · 26/09/2026
When did stage 3B lung cancer become “early stage”? A new Perspective from Raja M. Flores, MD, MPH cancerletter.com/perspective/202609…
cancerletter.com
When did stage 3B lung cancer become “early stage”? - The Cancer Letter
My recent column about Merck’s television commercial for perioperative Keytruda left me with a question I could not shak
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