Reposted by CalebiroLab
A new paper proposes an ‘intracrine’ signaling mechanism whereby a G protein-coupled receptor (FFA4) senses locally released fatty acids on intracellular membranes associated with lipid droplets to efficiently regulate lipolysis in adipocytes
www.nature.com/articles/s41...
nature.com
Intracrine FFA4 signaling controls lipolysis at lipid droplets - Nature Chemical Biology
An ‘intracrine’ signaling mechanism is proposed whereby a G-protein-coupled receptor (free fatty acid receptor 4) senses locally released fatty acids on intracellular membranes associated with lipid d...