It's out now in Nature Metabolism 💉 Most obesity meds hit 1-2 hormone receptors (GLP-1R ± GIPR), and they're quite effective, but doses a being pushed to achieve greater weight loss = more side effects.
We combined retatrutide (GLP-1R/GIPR/GCGR) with cagrilintide (AMLNR/CALCR) in obese rats.
nature.com
Cagrilintide and retatrutide combination therapy enhances weight loss and metabolic outcomes in obese male rats - Nature Metabolism
Combination therapy with retatrutide and cagrilintide lowers body weight and improves markers of metabolic health in obese, male rats more efficiently than equimolar monotherapies and matched-dose com...
