iiinova — where your digital self keeps evolving

Buchholz Lab @buchholzlab.bsky.social · 09/10/2026

We had our stars on stage, Manavi Jain and Lukas Theo Schmitt, at ZUGEHÖRT! – the Citizens' Forum on Cell and Gene Therapies by SaxoCell Cluster – on Oct 7 at Deutsches Hygiene-Museum! 👏 So good to make science accessible to the public! #CellAndGeneTherapy #ScienceForAll / #WissenschaftVermittelt

Manavi and Lukas talking on stage at DHMD - talking about their research on genome editing and designer recombinases (molecular tools designed to make targeted changes to DNA for future therapeutic applications).

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Buchholz Lab @buchholzlab.bsky.social · 10/09/2026

As part of ONCOnnect Dresden’s contribution to the evaluation of the EKFS Medical Scientist Kollegs in Frankfurt/Main on 7 Sep 2026, Pascal Wang from our lab gave a presentation on ‘Restoring cancer genomes: A base editing platform for precision oncology’. #CGT #medicine #oncology #science

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Buchholz Lab @buchholzlab.bsky.social · 25/08/2026

On August 21, Frank Buchholz joined the Dresden Summer Reception and brought the topic of spin-offs to the stage - sharing insights into the dynamic world of startups that bridge the gap between research and industry. Thank you to everyone who contributed to this inspiring evening! 👏

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Buchholz Lab @buchholzlab.bsky.social · 19/08/2026

Thrilled to have been part of this year’s CRISPR Frontiers meeting at Cold Spring Harbor Laboratory - an inspiring few days of exciting science and great discussions! In memory of Prof. J. Michael Bishop. #CSHL2026 #GenomeEngineering #GeneEditing #MichaelBishopLegacy #InspiringScience

Frank Buchholz takes his picture in front of a black and white poster-size photo showing J. Michael Bishop.

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Buchholz Lab @buchholzlab.bsky.social · 30/06/2026

Read Frank Buchholz's latest Nature Biotechnology article! A must-read for researchers in functional genomics. lnkd.in/d98vhQwN

lnkd.in

This link will take you to a page that’s not on LinkedIn

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Buchholz Lab @buchholzlab.bsky.social · 22/05/2026

An inspiring week at ASGCT2026 in Boston! Haidy Saleh Hassan from our team resented her work on multiplex (epi)gene editing of T cell inhibitory pathways to enhance persistence and function of adoptive T cell therapy in solid tumors, addressing a key challenge in patient relapse. #GenomeEditing

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Buchholz Lab @buchholzlab.bsky.social · 27/03/2026

Dont' miss "you ask WE EXPLAIN" with Frank Buchholz tomorrow at 7 PM at MPI-CBG!

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Buchholz Lab @buchholzlab.bsky.social · 13/03/2026

Looking forward to seeing you at Dennis’s talk on Monday!

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Buchholz Lab @buchholzlab.bsky.social · 03/03/2026

Join us for an exciting seminar by Dennis Kappei (CSI Singapore & NUS) on "Hyperactivation of the ALT Pathway: Persistent Telomeric Bridge Formation" – exploring how ALT hyperactivation could pave the way for new cancer therapies! 📅 16 March, 5 PM 📍 UKD H66, 3rd floor #CancerResearch #Genomics #NUS

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Buchholz Lab @buchholzlab.bsky.social · 24/02/2026

Meet Dr. Shady Sayed, a pioneering translational scientist in the national Translational Tandem Program for Gene- and Cell-based Therapies! Read Shady’s inspiring interview and discover how CRISPR-based technologies are driving innovation in medicine! www.nationale-strategie-gct.de/en/funding/p...

nationale-strategie-gct.de

Fellow-Interview Sayed

Die Nationale Strategie GCT soll durch gezielte Förderung und Vernetzung den Transfer von gen- und zellbasierten Therapien in die Praxis beschleunigen

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Reposted by Buchholz Lab

Buchholz Lab @buchholzlab.bsky.social · 10/02/2026

Ricardo Ruijpers from Helmholtz Institute & TU Munich will be joining us to discuss: "Harnessing HERV Envelopes for targeted RNA delivery". When? Monday, 23 February 2026, at 10:00 AM Where? BIOZ, 5th floor, Rooms 1+2 Hosted by: Prof. Dr. Frank Buchholz #Innovation #RNAResearch #ScienceSeminar

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Reposted by Buchholz Lab

CTGCT (Centre for the Technologies of Gene and Cell Therapy) @ctgct.bsky.social · 12/02/2026

Can we "erase" cancer by fixing a single DNA typo? Dr. Sayed, from @tudresden.bsky.social, is pioneering the use of CRISPR base editors to rewrite mutations in the P53 gene, the "guardian of the genome." Read how this technology is the future of personalized medicine: ctgct.si/en/objave/mo...

ctgct.si

Molecular Surgery: How Base Editors are Rewriting the Future of Cancer Therapy - CTGCT

Imagine being able to open the "instruction manual" of a human cell and fix a single typo that causes a life-threatening disease. This is no longer science fiction; it is the reality of base editors, ...

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Buchholz Lab @buchholzlab.bsky.social · 10/02/2026

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Buchholz Lab @buchholzlab.bsky.social · 02/12/2025

🎉 We’re thrilled to announce that we have been granted a European patent for our groundbreaking work on "Methods and Means for Genetic Alteration of Genomes Utilizing Designer DNA Recombining Enzymes"! A huge thank you to everyone involved in this achievement! #GenomeEditing #Innovation #TUDresden

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Buchholz Lab @buchholzlab.bsky.social · 27/11/2025

Revolutionizing Cancer Research! Dr. Haidy Saleh Hassan wins the 2025 Dissertation Award from Kulturstiftung Dresden of Commerzbank for Innovative Cancer Research for her groundbreaking work on glioblastoma treatment using adaptable immune cells! 🎉👏 #CancerResearch #Innovation #DresdenAward

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Buchholz Lab @buchholzlab.bsky.social · 14/11/2025

Dr. Ludwig Mayerlein (Synovo GmbH) will discuss high-yield platforms for Marburg virus glycoprotein production and purification, addressing both innovation and scale-up challenges. Nov 17, 11:00 AM | CRTD SR3 All are welcome! #Science #Vaccines #MarburgVirus #Dresden #CMCB

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Buchholz Lab @buchholzlab.bsky.social · 12/11/2025

Our #BaseEditing paper is DG-GT’s “Paper of the Quarter”! 🎉 We used precise gene editing to correct cancer mutations in TP53 – and watched as corrected cells nearly vanished. A step toward mRNA therapies for cancer! 💡 Full paper: rdcu.be/exqtH #CancerResearch #GeneEditing #Science #DG_GT

rdcu.be

A base editing platform for the correction of cancer driver mutations unmasks conserved p53 transcription programs

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Buchholz Lab @buchholzlab.bsky.social · 06/11/2025

Our lab shone at EMBO Workshop CRISPR-Cas: From Biology to Therapeutic Applications in Sorrento! Haidy presented her award-winning poster on modulating anti-tumor efficacy & T cell exhaustion! 🏆Frank shared insights on developing a BE platform for cancer research. #CRISPR #EMBO #Science #GeneEditing

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Buchholz Lab @buchholzlab.bsky.social · 04/11/2025

We’re live! The Buchholz Lab’s 'CanCorrect' project has begun, funded by a BMFTR VIP+ grant. This grant will help us take our research to the next level, with the goal of advancing personalized cancer therapy. #CancerResearch #CRISPR #Science #Innovation #BMFTR

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Buchholz Lab @buchholzlab.bsky.social · 30/10/2025

Shaping the future of healthcare! Frank Buchholz was part of the German Federal Ministry of Health’s event in Berlin to discuss ATMP Innovation Centers. Exciting discussions on how advanced therapies can transform patient care. #Innovation #Healthcare #ATMP #FutureOfMedicine #CarstenMüller-Tidow

Carsten Müler-Tidow and Frank Buchholz smiling to the camera in front of the ministry's photo board.

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Buchholz Lab @buchholzlab.bsky.social · 28/08/2025

Rewriting the Code of Life: A “The Scientist Speaks” podcast with Frank Buchholz on programmable recombinases Tune in to hear Frank’s insights and discover how this innovation is shaping the future of medicine and beyond!

podcasts.apple.com

The Future of Gene Editing with Programmable Recombinases

Podcast-Folge · The Scientist Speaks · 27.08.2025 · 16 Min.

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Buchholz Lab @buchholzlab.bsky.social · 31/07/2025

🎉 Buchholz Lab's new study uses base editing to target TP53 mutations in cancer! We fixed mutations in various cell lines, revealing key insights for precision therapies. Big congrats to our team! 👏 Read more here 🔗 kurzlinks.de/p9r6

link.springer.com

A base editing platform for the correction of cancer driver mutations unmasks conserved p53 transcription programs

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Buchholz Lab @buchholzlab.bsky.social · 17/06/2025

Frank Buchholz has been awarded the ERC Advanced Grant for groundbreaking research on genome editing a second time! 🎉 His project titled “DNA-binding domain Conditioned Precision Genome Editing” has been selected for funding!

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