iiinova — where your digital self keeps evolving

Bruno Sarmento @brunocsarmento.bsky.social · 30/09/2026

We came together to say “see you soon” to Catarina Pacheco and José das Neves. Their time with us is intertwined with the history of our group and so many of our achievements, joyful moments and milestones. Thank you for everything and see you soon!

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Bruno Sarmento @brunocsarmento.bsky.social · 26/09/2026

Meet our group member Carolina Avelãs! Carolina is a MSc student working on Targeted Dermal Delivery via Nanoparticle-Loaded Microneedles. You can find more about her work at www.i3s.up.pt/personal-inf... #dissolvingmicroneedles #melanoma #transdermaldrugdelivery @i3suporto.bsky.social

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Bruno Sarmento @brunocsarmento.bsky.social · 16/09/2026

Meet our group member Camino Garcia-Blasco. Camino is a visiting PhD Student from @ehu.eus working on development of MSC-based therapies for IBD. You can find more about her work at i3s.up.pt/personal-inf... @i3suporto.bsky.social

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Bruno Sarmento @brunocsarmento.bsky.social · 12/09/2026

Meet our group member Virgilio Piccolo! Virgilio is a PhD Student at Univerisity of Naples Federico II. He is currently working on cancer nanomedicines for RNA delivery. Find more about work at lnkd.in/eAaBDj2h In free time, Virgilio likes to listen music, watch films and drink beer with friends.

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Bruno Sarmento @brunocsarmento.bsky.social · 10/09/2026

Honored to participate as Plenary Speaker at #IPTS2026 in Ankara, discuss biologics formulation and interface between nanobiotechnology and advanced drug delivery. Thanks to organizers, particularly Prof. Erem Bilensoy, for the invitation and a stimulating meeting. ipts-hacettepe.org

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Bruno Sarmento @brunocsarmento.bsky.social · 04/09/2026

Honoured to receive an Honorary Doctorate from the University of Buenos Aires. This distinction reflects a journey built on collaboration, outstanding colleagues, dedicated team members and the support of institutions that made our scientific ambitions possible. www.ffyb.uba.ar/bruno-sarmen...

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Bruno Sarmento @brunocsarmento.bsky.social · 07/08/2026

Intersection of gene therapy and nanomedicine for intestinal fibrosis, a major unmet challenge in #IBD @J Control Release doi.org/10.1016/j.jc... Moving beyond controlling inflammation towards molecular reprogramming of fibrotic pathways with RNA therapeutics and targeted nanodelivery.

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Bruno Sarmento @brunocsarmento.bsky.social · 27/07/2026

A demanding year tough, rewarding, full of ups & downs, but a positive one overall. Our NTDD group @i3suporto.bsky.social took a day out in nature to relax, recharge & bond before a new, equally challenging year begins. Vacation days coming soon too!

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i3S - Institute for Research and Innovation in Health | UPorto @i3suporto.bsky.social · 23/07/2026

GlioBrain-Plate, an i3S-led project, aims to develop a pre-clinical platform to test new therapies targeting solid brain tumors. Now that the team has finished HiTech 2026, the project is ready for the next step toward reaching the market. 📰👀👇 #i3Sresearch #i3Sinnovation

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i3S acelera valorização de terapias para tumores cerebrais

Investigadoras do instituto concluíram um dos principais programas nacionais de transferência de tecnologia para projetos de investigação.

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Bruno Sarmento @brunocsarmento.bsky.social · 10/07/2026

It is a great honor to officially begin my term as President of the Controlled Release Society. It was especially meaningful to be inducted in Portugal during #CRS2026. I look forward to work closely with the CRS community, the Board of Directors, and our members to advance the Society’s mission.

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Bruno Sarmento @brunocsarmento.bsky.social · 10/07/2026

Great @CRSScience #CRS2026. Proud to share our work @i3S_UPorto and engage with drug delivery community as Tanja Weil, Chunying Chen, Paula Hammond, @NPeppas, Michael Bevilacqua and many others. Thanks to AMPC, led by Helena Florindo, and everyone who made this meeting a success.

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Bruno Sarmento @brunocsarmento.bsky.social · 04/07/2026

The #CRS2026 Annual Meeting is almost here! Our group will contribute with multiple oral presentations, posters and chaired sessions. Privilege to welcome the global delivery science community in #Lisbon and a great honour to begin my term as President @CRSScience. See you there!

crs2026annualmeeting.eventscribe.net

CRS 2026 Annual Meeting & Exposition

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Bruno Sarmento @brunocsarmento.bsky.social · 19/06/2026

Honored to be the Opening Keynote Speaker at the #CRAFT2026 Research Symposium in #Toronto. Excited to share our latest advances in microengineered 3D multicompartmental platforms for drug screening across complex tissue and disease models. #Nanomedicine #BiomedicalEngineering

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Bruno Sarmento @brunocsarmento.bsky.social · 14/06/2026

Lovely 2026 NTDD Retreat! Hosted at Pharmacy Museum, we had a testimonial from Dr José Brito da Silva @IPOPorto on treating colorectal cancer patients, inspiring roundtable with NTDD alumni on life during and after PhD, team-building fun, and Santo António “sardinhada” at sunset

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Bruno Sarmento @brunocsarmento.bsky.social · 06/06/2026

Our latest study, led by Sofia Dias, establishes a 3D multicellular intestinal model with capillary-like flow that better predicts drug permeability compared with conventional 2D systems and represent a promising #NAMs for early-stage drug development. lnkd.in/etPU2wi2

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Bruno Sarmento @brunocsarmento.bsky.social · 02/06/2026

Meet our group member Maria João! Maria João is Junior Researcher working on anisotropic nanoparticles, mucus transport, diabetes, biopharmaceuticals, oral delivery. You can find more about her work at www.i3s.up.pt/personal-inf... #nanomedicine #drugdelivery #mucosalsurfaces @i3suporto.bsky.social

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Bruno Sarmento @brunocsarmento.bsky.social · 29/05/2026

Almost closing 3 inspiring days at the @eufeps Annual Meeting in beautifull #Naples with my invited talk on our work on FcRn-targeted nanoplatforms for oral delivery of biologics. Thanks Erem Bilensoy for the invitation and organizing the BABP session! annualmeeting.eufeps.org

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Bruno Sarmento @brunocsarmento.bsky.social · 17/05/2026

Honored to open the 22nd European Drug Absorption Network meeting tonight as Plenary Speaker at @universitysofia on “Shuttles, Shortcuts & Functional Nanocarriers for Oral Protein Delivery.” Thanks Zahari Vinarov for invitation and excellent organization. #Nanomedicine #EDAN

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Bruno Sarmento @brunocsarmento.bsky.social · 13/05/2026

SUPERATE project is working to change that. Our main goal is to develop mucodiffusive anisotropic nanoparticles for the oral delivery of antidiabetic peptides, improving their oral bioavailability and paving the way for more patient-friendly therapies.

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Bruno Sarmento @brunocsarmento.bsky.social · 07/05/2026

Honored to attend #CRSBrazil2026 in #Goiania and participate in round table discussions on rational design and translational in drug delivery, with excellent line-up of international speakers. Thanks to @brazilcrs and Eliana Lima for outstanding organization. www.even3.com.br/e/crs-brazil...

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Bruno Sarmento @brunocsarmento.bsky.social · 04/05/2026

Congratulations to Ana Baião on successfully defending her PhD! Her work on the development of a novel combination therapy for colorectal cancer, combining CD44v6-targeted chemotherapy with immunotherapy, is truly remarkable. Well-done! @i3suporto.bsky.social ICBAS #nanomedicines

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Bruno Sarmento @brunocsarmento.bsky.social · 26/04/2026

Two recent collaborative publications on advancing nanomedicine! Original work on drug delivery across the BBB through post-insertion functionalization of lipid nanocapsules with cannabidiol using click chemistry doi.org/10.1016/j.co...

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Bruno Sarmento @brunocsarmento.bsky.social · 13/04/2026

Honored to be inducted @aimbe-official.bsky.social College of Fellows. Recognition highlights my outstanding group in advancing bioengineered nanomedicines and biomimetic 3D multicompartmental tissue models. Looking forward to advocating for AIMBE! aimbe.org/press/sarmen... @i3suporto.bsky.social

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Bruno Sarmento @brunocsarmento.bsky.social · 24/03/2026

These days in #Prague actively participating in the PBP World Meeting. This is a valuable opportunity to showcase our work within the #Genegut project and to explore collaborations around other 3D models we have developed. #worldmeeting worldmeeting.org

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Bruno Sarmento @brunocsarmento.bsky.social · 13/03/2026

Congratulations to Helena Almeida for brilliantly defend her PhD on Engineering anisotropic nanoparticles as carriers for the oral administration of therapeutic peptides, Well-done! @i3suporto.bsky.social @ICBAS #nanomedicines

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Bruno Sarmento @brunocsarmento.bsky.social · 10/03/2026

Latest paper led by Rui Moura, collab with @AnnedesRieux @UCLouvain_be now @JCRnEDITORS. Lipid nanocapsules with retinoic acid significantly reduced disease severity and attenuated demyelination in encephalomyelitis model. doi.org/10.1016/j.jc... #MultipleSclerosis #i3SPapers

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Bruno Sarmento @brunocsarmento.bsky.social · 06/03/2026

A truly emotional and professional pleasure to return to #Saarbrücken 20 years later to share our latest research on 3D intestinal models for drug screening. Great discussions at CRS DeChAt Local Chapter meets BioBarriers, an inspiring event bringing together fantastic science and people.

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Bruno Sarmento @brunocsarmento.bsky.social · 02/03/2026

Excited to present our ongoing project SUPERATE. We’re engineering self‑propulsive #nanoparticles that move through intestinal mucus with super‑diffusive transport to enable oral delivery of insulin and improve type 1 diabetes management. #nanomedicine @FCT @i3suporto.bsky.social

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Bruno Sarmento @brunocsarmento.bsky.social · 20/02/2026

In #Stockholm these days for #ECCO2026, following recent advances in Crohn’s and Colitis treatment, presenting our work at @i3suporto.bsky.social on targeted drug delivery for #IBD and pleased to congratulate Sofia Barros on her well-deserved ECCO Research Grant. #DrugDelivery @GENEGUT_EU

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Bruno Sarmento @brunocsarmento.bsky.social · 07/02/2026

Congratulations to Ana Baião and Paulo Faria on being awarded a scholarship from Liga Portuguesa Contra o Cancro - Núcleo Regional Norte! This support allow to expand their important work on nanomedicines to treat colorectal and brain tumors. #CancerNanomedicines @i3suporto.bsky.social

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Bruno Sarmento @brunocsarmento.bsky.social · 15/01/2026

We’re proud to actively participate in the XVI SPLC-CRS Conference SPLC-CRS (Spanish Portuguese Local Chapter)! Sharing another round of recent, cutting-edge research results with a strong @i3suporto.bsky.social team representing us in #Albacete. #SPLC2026

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Bruno Sarmento @brunocsarmento.bsky.social · 12/01/2026

NTDD @i3suporto.bsky.social turns 9! Celebrating 9 years of science, innovation, and teamwork, and marking the occasion with a get-together at @CaféPiolho. Thank you to our amazing group and collaborators! #Anniversary #DrugDelivery

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Bruno Sarmento @brunocsarmento.bsky.social · 06/01/2026

First paper published in 2026 is out and is a blast! We show that CD44v6-targeted irinotecan nanoparticles + anti-PD-L1 immunotherapy considerably enhance tumor suppression in vivo. Work led by @AnaBaião, now online in @JCRnEDITORS doi.org/10.1016/j.jc... #i3SPapers #Nanomedicine @CRS_FG_NANO

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Bruno Sarmento @brunocsarmento.bsky.social · 16/12/2025

Using our 3D intestinal inflamed model, we validated a new therapeutic strategy of mesalazine-loaded chitosan/alginate nanoparticles to effectively reduced the pro-inflammatory state. Collaboration with @Unesp now online in @CarbohydratePolymers doi.org/10.1016/j.ca... #Genegut #i3Spapers

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Bruno Sarmento @brunocsarmento.bsky.social · 25/11/2025

Take a look on our recent paper at @JCREditors and learn how IBD-specific stimuli can be used to design smarter and more precise nanotherapies. Discover how disease hallmarks can guide drug delivery. #i3SPapers #nanomedicines #IBD doi.org/10.1016/j.jc...

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Bruno Sarmento @brunocsarmento.bsky.social · 21/11/2025

While receiving the @caixaresearch.bsky.social Award in #Barcelona to support our project on nanomedicines to treat glioblastoma, our latest results presented at IV ASPI–ASEICA Meeting in #Compostela by Catarina Pacheco. Proud of the work of this team @i3suporto.bsky.social ! shorturl.at/ucCVz

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caixaresearch.bsky.social @caixaresearch.bsky.social · 20/11/2025

19/ 🔚We have reached the end of the event! Thank you for joining us and for your commitment to the future of health. Congratulations to all the selected projects!🎉👏 Stay tuned, we’ll be sharing more highlights and details from the ceremony soon!👀

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i3S - Institute for Research and Innovation in Health | UPorto @i3suporto.bsky.social · 20/11/2025

Our community is celebrating once again: three projects led by #i3S researchers Diogo Castro, Ana Paula Pêgo, and Bruno Sarmento were awarded today by the @caixaresearch.bsky.social, totaling three million euros in funding. Congratulations! 👏 📰 tinyurl.com/y3ehbkp7

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caixaresearch.bsky.social @caixaresearch.bsky.social · 20/11/2025

1/ 🧠 Therapies for glioblastoma, the most lethal brain cancer, often fail due to the tumour’s difficult accessibility. With a #HealthResearch grant, @brunocsarmento.bsky.social is developing an implant that releases drugs directly into the brain. 👇 tinyurl.com/yrfpjd3n

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Bruno Sarmento @brunocsarmento.bsky.social · 14/11/2025

Happy to be invited again to talk at @RICIFA2025, ricifa.com.ar in Buenos Aires and share our work on functional #nanomedicines for Inflammatory Bowel Disease.

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Bruno Sarmento @brunocsarmento.bsky.social · 04/11/2025

Congratulations to João Almeida for successfully defend his MSc thesis in Metabolism – Biopathology and Experimental “Nanomedicines targeting intestinal Fc receptor to enhance the oral delivery of antidiabetic peptides” at @FMUPorto. Well-done!

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Bruno Sarmento @brunocsarmento.bsky.social · 30/10/2025

It was a pleasure to return to #CIFARP2025 in Ribeirão Preto, meet so may friends and present our work developed at @i3suporto.bsky.social on innovative 3D multicompartmental models for drug screening. Excited to contribute to the launch of INCT Nanofarma, and I am looking forward to what’s ahead!

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Bruno Sarmento @brunocsarmento.bsky.social · 24/10/2025

Meet our group member Diana Ribeiro! Diana is a PhD Student working on psoriasis-like skin models for pre-clinical testing of therapies under a fellowship from FCT. Find more about her work at www.i3s.up.pt/personal-inf... #psoriasisvulgaris #skinmodels #pre-clinicaltesting @i3suporto.bsky.social

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Bruno Sarmento @brunocsarmento.bsky.social · 16/10/2025

Attending the @mpsnova.bsky.social INTERIM Meeting @Nova Medical School and present our work on multicompartimental /multicomponent 3D immunospheroid models for drug screening. Learn more about this exiting Twinning Project: mpsnova.itqb.unl.pt

mpsnova.itqb.unl.pt

Home - MPS NOVA

By bringing together leading European institutions in Microphysiological Systems and stem cell research, MPS_NOVA will expand expertise and methodologies in

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