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Brian

@brianmackenna.bsky.social
429 followers 283 following 321 posts

Pharmacist | MPH | Data

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Brian @brianmackenna.bsky.social · 28/09/2026
More from @news.rte.ie on the Irish health service's growing use of opioids. I wrote about this on Linkedin earlier this year www.linkedin.com/pulse/irish-...
linkedin.com
The Irish health service needs to confront its opioid problem
Recent research shows Ireland has amongst the highest over-the-counter codeine sales internationally, and that prescriptions for painkillers, particularly opioids, have risen steadily over the last de...
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Brian @brianmackenna.bsky.social · 28/09/2026
More from @news.rte.ie on the Irish health service's growing use of opioids. I wrote about this on Linkedin earlier this year www.linkedin.com/pulse/irish-...
linkedin.com
The Irish health service needs to confront its opioid problem
Recent research shows Ireland has amongst the highest over-the-counter codeine sales internationally, and that prescriptions for painkillers, particularly opioids, have risen steadily over the last de...
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Reposted by Brian
Brian @brianmackenna.bsky.social · 22/09/2026
Respiratory Folk New AIR/MART inhaler measure to monitor the impact of the changes introduced in the BTS/NICE/SIGN asthma guideline across English general practices and hospitals Audit your organisations progress! www.bennett.ox.ac.uk/blog/2026/09... #medsky #pharmsky
bennett.ox.ac.uk
New AIR/MART inhaler measure launched in OpenPrescribing and OpenPrescribing Hospitals | Bennett Institute for Applied Data Science
New AIR/MART inhaler measure has launched in OpenPrescribing and OpenPrescribing Hospitals
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Brian @brianmackenna.bsky.social · 22/09/2026
Respiratory Folk New AIR/MART inhaler measure to monitor the impact of the changes introduced in the BTS/NICE/SIGN asthma guideline across English general practices and hospitals Audit your organisations progress! www.bennett.ox.ac.uk/blog/2026/09... #medsky #pharmsky
bennett.ox.ac.uk
New AIR/MART inhaler measure launched in OpenPrescribing and OpenPrescribing Hospitals | Bennett Institute for Applied Data Science
New AIR/MART inhaler measure has launched in OpenPrescribing and OpenPrescribing Hospitals
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Bennett Institute for Applied Data Science @bennettoxford.bsky.social · 17/09/2026
For #WorldPatientSafetyDay, we’re highlighting two OpenPrescribing measures that help NHS teams examine the prescribing of oral morphine solution.  🔍Explore the measures: openprescribing.net/measure/morphin… openprescribing.net/measure/morphin…
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Reposted by Brian
Primary Healthcare Specialist Group (British Computer Society) @phcsg.bsky.social · 15/09/2026
🚨 Our speaker line-up is shaping up to be something special! Hear from Prof. Ben Goldacre, Brian MacKenna, Dr Anne-Marie Cunningham, Prof. Tony Avery, Prof. Simon de Lusignan & Dr Neil Paul at the BCS PHCSG Annual Conference & Education Day 2026. 12-13 November - Oxford 🎟️ tinyurl.com/PHCSGConf26
tinyurl.com
45th Annual Conference, Education Day & AGM 2026
The BCS Primary Health Care Specialist Group (PHCSG) is holding its 45th Annual Conference at the voco Oxford Thames hotel, near Oxford. Join us on Thursday 12 November-Friday 13 November 2026 from 9:...
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Reposted by Brian
Brian @brianmackenna.bsky.social · 09/09/2026
🧵 1/6 📢 New on OpenPrescribing-Hospitals: subcutaneous pembrolizumab hospitals.openprescribing.net/measures/pem... We’ve rapidly added a new measure so you can see how every NHS hospital is getting on with the rollout of rapid pembrolizumab injections. #medsky #pharmsky
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Brian @brianmackenna.bsky.social · 09/09/2026
🧵 1/6 📢 New on OpenPrescribing-Hospitals: subcutaneous pembrolizumab hospitals.openprescribing.net/measures/pem... We’ve rapidly added a new measure so you can see how every NHS hospital is getting on with the rollout of rapid pembrolizumab injections. #medsky #pharmsky
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Brian @brianmackenna.bsky.social · 18/08/2026
Teplizumab (Tzield) and the NHS. NICE has recommended teplizumab for delaying the onset of stage 3 type 1 diabetes in people aged 8+ with stage 2 T1D. So..................... How much is the NHS actually using it? #MedSky #PharmaSky #T1D
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Brian @brianmackenna.bsky.social · 18/08/2026
Teplizumab (Tzield) and the NHS. NICE has recommended teplizumab for delaying the onset of stage 3 type 1 diabetes in people aged 8+ with stage 2 T1D. So..................... How much is the NHS actually using it? #MedSky #PharmaSky #T1D
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Reposted by Brian
Brian @brianmackenna.bsky.social · 11/08/2026
What does the NHS actually record most often about us? It’s probably not what you think. We looked at the most frequently recorded clinical codes in NHS GP records 👇 New(ish) blog and quick 🧵 www.bennett.ox.ac.uk/blog/2026/03...
bennett.ox.ac.uk
What Are the Top 10 Most Frequently Recorded Clinical Codes in NHS GP Records | Bennett Institute for Applied Data Science
OpenCodeCounts is an open-access, online interactive tool - we use it to find the 10 most used codes across general practice in England.
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Hayley Wickens @bughayleyw.pharmsky.app · 11/08/2026
Always interesting to see what is going on with data in the NHS... Nice new tool to play with too! 👏
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Brian @brianmackenna.bsky.social · 11/08/2026
What does the NHS actually record most often about us? It’s probably not what you think. We looked at the most frequently recorded clinical codes in NHS GP records 👇 New(ish) blog and quick 🧵 www.bennett.ox.ac.uk/blog/2026/03...
bennett.ox.ac.uk
What Are the Top 10 Most Frequently Recorded Clinical Codes in NHS GP Records | Bennett Institute for Applied Data Science
OpenCodeCounts is an open-access, online interactive tool - we use it to find the 10 most used codes across general practice in England.
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Nick DeVito @ndevito1.bsky.social · 31/07/2026
Good morning! Check this out! Share it with your friends! Think about things to submit! We’d love to see you there!
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Euan Reid @euanreid.pharmsky.app · 30/07/2026
Are tocilizumab & sarilumab equally effective for severe COVID-19? A new @natcomms.nature.com study of 10k+NHS hospital patients in England 🏴󠁧󠁢󠁥󠁮󠁧󠁿 & Scotland 🏴󠁧󠁢󠁳󠁣󠁴󠁿 shows no difference in 28-day mortality or time to discharge. Both IL-6 inhibitors are equally effective options www.nature.com/articles/s41...
nature.com
Tocilizumab versus sarilumab among adults hospitalised with COVID-19: target trial emulation across England and Scotland - Nature Communications
Using electronic health record databases in England and Scotland, this study compared tocilizumab and sarilumab in over 10,000 hospitalised COVID-19 patients and found no meaningful difference in surv...
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Reposted by Brian
Brian @brianmackenna.bsky.social · 30/07/2026
The Bennett conference returns to Oxford! December 8th and 9th Open code in science Read more and register www.bennett.ox.ac.uk/blog/2026/07...
bennett.ox.ac.uk
Coming 8-9 December: The 2026 Bennett Oxford Symposium on Open Code in Science | Bennett Institute for Applied Data Science
Join us for the 2026 Bennett Oxford Symposium on Open Code in Science
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Brian @brianmackenna.bsky.social · 30/07/2026
The Bennett conference returns to Oxford! December 8th and 9th Open code in science Read more and register www.bennett.ox.ac.uk/blog/2026/07...
bennett.ox.ac.uk
Coming 8-9 December: The 2026 Bennett Oxford Symposium on Open Code in Science | Bennett Institute for Applied Data Science
Join us for the 2026 Bennett Oxford Symposium on Open Code in Science
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Brian @brianmackenna.bsky.social · 20/07/2026
Tocilizumab versus sarilumab among adults hospitalised with COVID-19: target trial emulation across England and Scotland New paper from OpenSAFELY and Scotland. doi.org/10.1038/s414... Blog from @lshtm.bsky.social Prof @laurietomlinson.bsky.social communities.springernature.com/posts/when-t...
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Brian @brianmackenna.bsky.social · 16/07/2026
This is a very enjoyable editorial even though its a long time since I worked in a hospital and had to deal with "DIY meds".
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Reposted by Brian
Bennett Institute for Applied Data Science @bennettoxford.bsky.social · 16/07/2026
🏥 Is andexanet alfa use changing in your hospital or region? Our latest blog post reviews the latest safety updates and shows how OpenPrescribing Hospitals can support local audits. Read more 👉 www.bennett.ox.ac.uk/blog/2026/07/a…
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Reposted by Brian
Jamie Cummins @jamiecummins.bsky.social · 14/07/2026
Today we launch the first stable release of RegCheck: v1.0.0. RegCheck makes it easier and quicker to compare study registrations to published papers for consistency - something we know is important in principle, but rarely done in practice. A 🧵 on what's new: regcheck.app
regcheck.app
RegCheck
RegCheck is an AI tool to compare preregistrations with papers instantly.
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Brian @brianmackenna.bsky.social · 13/07/2026
Our poster on this very topic is now up at #ISTH2026 Go and speak to the excellent Vicky Speed about the lovely OpenPrescribing.
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Reposted by Brian
Brian @brianmackenna.bsky.social · 11/07/2026
Andexanet alfa: data and tools to audit your use in England just in time for #ISTH2026 www.bennett.ox.ac.uk/blog/2026/07... #hemesky #medsky #pharmsky short thread 🧵
bennett.ox.ac.uk
Andexanet alfa: a safety audit using OpenPrescribing Hospitals | Bennett Institute for Applied Data Science
An analysis of andexanet alfa issuing in NHS trust in England using OpenPrescribing Hospitals
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Brian @brianmackenna.bsky.social · 11/07/2026
Andexanet alfa: data and tools to audit your use in England just in time for #ISTH2026 www.bennett.ox.ac.uk/blog/2026/07... #hemesky #medsky #pharmsky short thread 🧵
bennett.ox.ac.uk
Andexanet alfa: a safety audit using OpenPrescribing Hospitals | Bennett Institute for Applied Data Science
An analysis of andexanet alfa issuing in NHS trust in England using OpenPrescribing Hospitals
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Reposted by Brian
Ben Goldacre @bengoldacre.bsky.social · 10/07/2026
HISTORIC MOMENT Today at 14:40 Dr Mark Russell from KCL pressed the button to execute the first ever job on the new OpenSAFELY service. Until today, OpenSAFELY was COVID only. Now we are open to critical analyses that improve all patient care, on GP records, securely, at scale. PICS! THREAD!
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Reposted by Brian
The Lancet Rheumatology @thelancetrheum.bsky.social · 03/07/2026
NEW RESEARCH—Trends in autoimmune rheumatic disease diagnoses before and after the COVID-19 pandemic in England: a population-based cohort study using @OpenSAFELY bit.ly/4p6WELY Plus linked Comment by @jeffsparks.bsky.social bit.ly/446onmh
Comparison between observed and expected diagnosis rates of autoimmune rheumatic diseases in England after the onset of the COVID-19 pandemic
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Brian @brianmackenna.bsky.social · 09/06/2026
Would you like to learn a little about how the Irish healthcare service uses painkillers? Me & the great @frankmoriarty.bsky.social Frank will be giving a run down of the magnificent CDRx project which shed new light on prescribing in the HSE. shorturl.at/O01B4 #SpeirGorm #pharmsky #medsky
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Reposted by Brian
Brian @brianmackenna.bsky.social · 03/06/2026
Ireland has amongst the highest over-the-counter codeine sales worldwide. Meanwhile opioid prescribing in Ireland has ↗️, whilst ↙️ in Eng. Me on why the Irish health service should confront its opioid use www.linkedin.com/pulse/irish-... brief🧵 #SpeirGorm #SpéirGhorm #pharmsky #medsky
linkedin.com
The Irish health service needs to confront its opioid problem
Recent research shows Ireland has amongst the highest over-the-counter codeine sales internationally, and that prescriptions for painkillers, particularly opioids, have risen steadily over the last de...
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Brian @brianmackenna.bsky.social · 03/06/2026
Ireland has amongst the highest over-the-counter codeine sales worldwide. Meanwhile opioid prescribing in Ireland has ↗️, whilst ↙️ in Eng. Me on why the Irish health service should confront its opioid use www.linkedin.com/pulse/irish-... brief🧵 #SpeirGorm #SpéirGhorm #pharmsky #medsky
linkedin.com
The Irish health service needs to confront its opioid problem
Recent research shows Ireland has amongst the highest over-the-counter codeine sales internationally, and that prescriptions for painkillers, particularly opioids, have risen steadily over the last de...
211
Reposted by Brian
Brian @brianmackenna.bsky.social · 03/06/2026
Ghost Branded Generics: Why does the cost of generic atorvastatin vary? A long nerdy tale about an issue that cost the NHS £11.6million in 2018 Spoiler: there is a happy end which I will write about later New Linkedin Newsletter out today - an oldie but a goodie! www.linkedin.com/pulse/ghost-...
linkedin.com
Ghost branded generics: Why does the cost of generic atorvastatin vary?
This a very nerdy story about a problem that costs the NHS £11.6m a year.
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Reposted by Brian
Ben Goldacre @bengoldacre.bsky.social · 21/05/2026
Inaugural Lecture Klaxon! Our magnificent CTO Seb Bacon is a hero of the modern age, and now PROFESSOR Seb Bacon... Come to his inaugural lecture in Oxford! OpenSAFELY! OpenPrescribing! TrialsTracker! OpenCorporates! Open Code! Open Everything! www.bennett.ox.ac.uk/blog/2026/05... bacon.boutique
bennett.ox.ac.uk
"On The Record" - Seb Bacon’s Inaugural Lecture | Bennett Institute for Applied Data Science
Come and join Seb for his inaugural lecture as the first-ever Professor of Practice at the Nuffield Department of Primary Care Health Sciences
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Reposted by Brian
Brian @brianmackenna.bsky.social · 13/05/2026
Ireland has amongst the highest over-the-counter codeine sales internationally. Meanwhile opioid prescribing in Ireland has risen, whilst falling in England. I wrote about why the Irish health service needs to confront its opioid problem on Linkedin: www.linkedin.com/pulse/irish-... brief🧵
linkedin.com
The Irish health service needs to confront its opioid problem
Recent research shows Ireland has amongst the highest over-the-counter codeine sales internationally, and that prescriptions for painkillers, particularly opioids, have risen steadily over the last de...
136
Brian @brianmackenna.bsky.social · 13/05/2026
Ireland has amongst the highest over-the-counter codeine sales internationally. Meanwhile opioid prescribing in Ireland has risen, whilst falling in England. I wrote about why the Irish health service needs to confront its opioid problem on Linkedin: www.linkedin.com/pulse/irish-... brief🧵
linkedin.com
The Irish health service needs to confront its opioid problem
Recent research shows Ireland has amongst the highest over-the-counter codeine sales internationally, and that prescriptions for painkillers, particularly opioids, have risen steadily over the last de...
136
Reposted by Brian
Brian @brianmackenna.bsky.social · 12/05/2026
Six editions into my Linkedin Medicines x Data newsletter now 👀 If NHS medicines/data/informatics nerd stuff is your thing, you can sign up here: www.linkedin.com/newsletters/...
linkedin.com
Medicines x Data | LinkedIn
Covering nerdy NHS medicines data topics that have been learnt while building and delivering tools!
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Brian @brianmackenna.bsky.social · 12/05/2026
Six editions into my Linkedin Medicines x Data newsletter now 👀 If NHS medicines/data/informatics nerd stuff is your thing, you can sign up here: www.linkedin.com/newsletters/...
linkedin.com
Medicines x Data | LinkedIn
Covering nerdy NHS medicines data topics that have been learnt while building and delivering tools!
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Trish Greenhalgh @trishgreenhalgh.bsky.social · 01/05/2026
This looks good. Software nerd takes on societal challenges. www.eventbrite.com/e/seb-bacons...
eventbrite.com
Seb Bacon’s Inaugural Lecture
I've been made Prof of Research Software Engineering. Want to listen to me waffle for an hour, and eat canapés, to mark the occasion?
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Brian @brianmackenna.bsky.social · 27/04/2026
Application deadline is Thursday! APPLY #medsky
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Nuffield Department of Primary Care Health Sciences @oxprimarycare.bsky.social · 17/04/2026
We were delighted to welcome alumni, students and academics to our Alumni Retreat 2026 at @hmcoxford.bsky.social Celebrating our global community while exploring AI & digital healthcare, the event showcased the impact, insight and leadership of our alumni network. Read more: bit.ly/4sIUvGr
A collage of images from the Alumni Retreat 2026 featuring alumni, staff, students and speakers
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Bennett Institute for Applied Data Science @bennettoxford.bsky.social · 13/04/2026
🧠📊Bennett’s CTO @bacon.boutique and Resident Pharmacist @brianmackenna.bsky.social joined the Alumni Retreat: AI & Digital Healthcare Systems to discuss how big data is transforming healthcare operations and improving lives. Learn more: www.bennett.ox.ac.uk/about-us/ @oxprimarycare.bsky.social
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Brian @brianmackenna.bsky.social · 03/03/2026
Category H now live on OpenPrescribing Example med openprescribing.net/tariff/?code... #pharmsky
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Ben Goldacre @bengoldacre.bsky.social · 23/02/2026
OpenSAFELY is open from today! Huge thanks to all who supported this vast collaboration: whole population GP data; in a productive platform; innovative privacy protections; unprecedented support from professions, privacy campaigners; &c Now it's over to users! www.bennett.ox.ac.uk/blog/2026/02...
bennett.ox.ac.uk
OpenSAFELY news: you can apply to do non-COVID research, from today! | Bennett Institute for Applied Data Science
We are delighted to announce that - from today - you can submit applications to the OpenSAFELY service for non-COVID-19 studies.
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The BMJ @bmj.com · 27/01/2026
New BMJ Research: Time trends in newly recorded diagnoses of 19 long term conditions before, during, and after the covid-19 pandemic: population based cohort study in England www.bmj.com/content/392/...
Figure
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Brian @brianmackenna.bsky.social · 26/01/2026
🚨 OpenSAFELY Milestone Paper! How did the pandemic affect diagnosis rates for chronic diseases? We analysed rates for 19 long-term conditions in 30m people in England. The results are out this week in @bmj.com 📄 Read here: doi.org/10.1136/bmj-...
doi.org
Time trends in newly recorded diagnoses of 19 long term conditions before, during, and after the covid-19 pandemic: population based cohort study in England using OpenSAFELY
Objective To evaluate temporal changes in rates of newly recorded diagnoses for 19 long term conditions in England in relation to the covid-19 pandemic by disease, age group, sex, socioeconomic status...
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Brian @brianmackenna.bsky.social · 26/01/2026
🚨 OpenSAFELY Milestone Paper! How did the pandemic affect diagnosis rates for chronic diseases? We analysed rates for 19 long-term conditions in 30m people in England. The results are out this week in @bmj.com 📄 Read here: doi.org/10.1136/bmj-...
doi.org
Time trends in newly recorded diagnoses of 19 long term conditions before, during, and after the covid-19 pandemic: population based cohort study in England using OpenSAFELY
Objective To evaluate temporal changes in rates of newly recorded diagnoses for 19 long term conditions in England in relation to the covid-19 pandemic by disease, age group, sex, socioeconomic status...
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BMJ Medicine @bmjmedicine.bsky.social · 19/12/2025
In this study, Rose Higgins and colleagues look at opioid prescribing in patients on orthopaedic waiting lists during the pandemic to understand the impact of longer elective wait times. bmjmedicine.bmj.com/content/4/1/e00…
bmjmedicine.bmj.com
Opioid prescribing to people on orthopaedic waiting lists during the covid-19 pandemic in England: retrospective cohort study using linked electronic health record data in OpenSAFELY-TPP
Objective To quantify the changes in opioid prescribing over time to a population with high rates of opioid use to understand the impact of longer elective wait times during the covid-19 pandemic.Desi...
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Brian @brianmackenna.bsky.social · 23/01/2026
OpenSAFELY 💪
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Darren Dahly @statsepi.bsky.social · 22/01/2026
Disease surveillance capacity is very useful, particularly when integrated with decision making by design. We should build even more. www.bmj.com/content/392/...
bmj.com
We must no longer accept waiting years to understand disease burden
One of the most important advances to emerge from the covid-19 pandemic is the ability to measure population health at unprecedented scale and speed. Our study of time trends for long term conditions,...
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Brian @brianmackenna.bsky.social · 22/01/2026
⏰New OpenSAFELY paper alert ⏰ Time trends in newly recorded diagnoses of 19 long term conditions before, during, and after the covid-19 pandemic: population based cohort study in England using OpenSAFELY www.bmj.com/content/392/... Out today in @bmj.com led by an expert team at Kings! #medsky 🧵
bmj.com
Time trends in newly recorded diagnoses of 19 long term conditions before, during, and after the covid-19 pandemic: population based cohort study in England using OpenSAFELY
Objective To evaluate temporal changes in rates of newly recorded diagnoses for 19 long term conditions in England in relation to the covid-19 pandemic by disease, age group, sex, socioeconomic status...
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Brian @brianmackenna.bsky.social · 16/01/2026
My weekend listening sorted!
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Brian @brianmackenna.bsky.social · 08/01/2026
New paper from our team out over Christmas in BJCP Trends and variation in the use of andexanet alfa for the reversal of direct oral anticoagulants in NHS trusts in England pubmed.ncbi.nlm.nih.gov/41406988/ Sometimes research becomes more relevant after you’ve written it 🧵 #medsky #haematology
pubmed.ncbi.nlm.nih.gov
Trends and variation in the use of andexanet alfa for the reversal of direct oral anticoagulants in NHS trusts in England - PubMed
The use of andexanet alfa varies markedly between NHS regions and between NHS trusts in England. This study is the first analysis of adoption of a new treatment using the OpenPrescribing Hospitals platform, which is expected to provide a generalizable framework for similar analyses in the future.
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