iiinova — where your digital self keeps evolving

Brain Case @braincase.bsky.social · 07/07/2026

🧠We are excited to share four recent customer publications 🎉 www.ebraincase.com/support/cust... Interested in exploring viral tools for your next project? 📩 Contact us to discuss your research needs: BD@ebraincase.com #Neuroscience #ResearchTools #AAV #NeuralEngineering #GeneTherapy

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Brain Case @braincase.bsky.social · 07/07/2026

🧬 In Vivo Validation: AAV Sparse Labeling System with mYongHong Fluorescent Protein 📩bd@ebraincase.com 👉https://www.ebraincase.com/ #AAV #Neuroscience #GeneDelivery #InVivoImaging

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Brain Case @braincase.bsky.social · 03/07/2026

🧠Breaking Through the BBB: Next-Gen AAV Mutants for CNS Gene Therapy Excited to share our latest work on engineering AAVhu.32 variants that efficiently cross the blood-brain barrier — without the liver toxicity burden of current AAVs 📩BD@ebraincase.com #GeneTherapy #Neuroscience #BloodBrainBarrier

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Brain Case @braincase.bsky.social · 03/07/2026

Nat. Neurosci.: First Red Fluorescent Acetylcholine Sensor Enables Multiplex In Vivo Imaging of Neurotransmitters We've highlighted the key advances and potential applications in our latest article: 👉 www.ebraincase.com/news/new-pro... #NatureNeuroscience #Neuroscience #BrainResearch #Biosensors

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Brain Case @braincase.bsky.social · 01/07/2026

🧬 AAV Gene Therapy in Bone Diseases: From Serotypes to Delivery Strategies 👉 Find more details in our latest blog post. www.ebraincase.com/support/Blog... For viral packaging services, please contact: bd@ebraincase.com #BoneRegeneration #OrthopedicResearch #BoneBiology #GeneTherapy #AAV

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Brain Case @braincase.bsky.social · 18/06/2026

BuBu is waiting for YOU in Singapore🐱✈️ Plushies✅ Tote bags✅ Mouse pads✅ Notebooks✅ ...... All free. All cute. All at Our Booth. Don't keep BuBu waiting — come get your merch before it's gone! 🏃‍♀️ www.ebraincase.com/news/corpora... #BuBu #BrainCaseBiotech #NEUROConclave2026 #FreeStuff #Neuroscience

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Brain Case @braincase.bsky.social · 17/06/2026

✨See You in Singapore at NEURO Conclave 2026 📍 Village Hotel Changi,Singapore 🌏We have small gifts waiting for you to pick up.🎁 If you are attending NEURO Conclave 2026, we warmly invite you to visit our booth and connect with our team. shorturl.at/aFV0n #NeuroConclave2026 #Singapore #Neuroscience

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Brain Case @braincase.bsky.social · 15/06/2026

🎉From Brain Case to VESSL — a new translational direction in regenerative aesthetics. MSC-derived exosomes, now INCI-named. 👉With VESSL, we are taking a careful first step into this space. ✨Rigor, transparency, responsible claims. www.vesslx.com #Biotechnology #SkinScience #RegenerativeAesthetics

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Brain Case @braincase.bsky.social · 15/05/2026

✨Recent Customer Article Collection✨🧬 At Brain Case Biotech, we're honored to contribute to the exciting advancements in neuroscience by supporting our customers with our viral vectors and tools. 🔗List: www.ebraincase.com/virus-produc... #BrainCaseBiotech #Neuroscience #GeneTherapy #ViralVector

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Brain Case @braincase.bsky.social · 14/05/2026

🧠Whole-Brain Neural Circuits at a Glance–High-Resolution Whole-Brain Transparency Imaging & Analysis from Us ✨ 💠Imaging speed:Whole brain in<2 hours 💠Resolution:0.5×0.5×2.5 μm³ 💠Throughput:1 trillion pixels per hour 💠Lasers:405, 488, 552, 640 nm 🔗 shorturl.at/PehWd #Neuroscience #WholeBrainImaging

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Brain Case @braincase.bsky.social · 09/05/2026

🎉🎉We’re growing! Brain Case Biotech has officially moved to our new standalone building. This upgrade reflects our commitment to advancing viral vector and plasmid research. Excited for the next chapter! 👉 www.ebraincase.com #BrainCaseBiotech #NewOffice #CompanyGrowth #BiotechInnovation

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Brain Case @braincase.bsky.social · 07/05/2026

🧠✨Literature Interpretation|About CaBLAM ✅ Superior single-trial SNR vs GCaMP6s. ✅ Over 5 hours of stable recording. ✅ No excitation light required. Learn more : www.nature.com/articles/s41592-025-02972-0 www.ebraincase.com/support/lite... #CaBLAM #BioluminescentCalciumIndicator #NathanCShanerLab

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Brain Case @braincase.bsky.social · 23/04/2026

✨ The Second Client Article Collection of April is here!🧬 The viral tools used in the above article are available from BrainCase, which also offers a variety of custom services. 📩 bd@ebraincase.com 🔗 www.ebraincase.com/support/cust... #BrainCaseBiotech #Neuroscience #GeneTherapy #ViralVectors

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Brain Case @braincase.bsky.social · 10/04/2026

✨The first Client Article Collection of April is here!🧬 🔬The viral tools used in the above article are available from BrainCase, which also offers a variety of custom services. For more information, please contact bd@ebraincase.com 🔗 www.ebraincase.com/virus-produc... #BrainCase #Neuroscience

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Brain Case @braincase.bsky.social · 02/04/2026

🧠 In vivo testing results of retrograde multi-synaptic tracing virus - Pseudorabies Virus (PRV) 🐁 🔹Product Number: BC-PRV-801-Plus 🔹Product Titer: 9.50E+09 PFU/mL 🔗 Click to view the latest batch Test Report： www.ebraincase.com/news/corpora... #BrainCaseBiotech #PRV801 #PseudorabiesVirus

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Brain Case @braincase.bsky.social · 30/03/2026

🌟 A collection of recent client articles. 🧬 We’re committed to providing the highest quality products and exceptional service🔬✨ If you have any product inquiries or research needs, feel free to reach out to us at bd@ebraincase.com 🔗 www.ebraincase.com #BrainCaseBiotech #Neuroscience #GeneTherapy

A midbrain–cortical circuit mediated by claustrum neuronal ensemble orchestrates drug-paired context memory processing
👉 https://doi.org/10.1172/jci196944

Sex-specific Effects of Acute Stress on Emergence from Isoflurane Anesthesia via Brainstem Circuitry in Mice
👉 https://doi.org/10.1097/aln.0000000000005826

Prefrontal cortex-to-hypothalamic outputs orchestrate cuepotentiated palatable food consumption via AMPKβ2 signaling
👉 https://www.nature.com/articles/s41421-025-00857-2

A bone-derived hormone permits rapid visual escape via GPR37 receptor in a subpopulation of VTA GABAergic neurons
👉 https://www.cell.com/neuron/abstract/S0896-6273(25)01004-9

The axon initial segment-associated microglia regulate neuronal activity and visual perception
👉 https://doi.org/10.1038/s41422-026-01218-8

Glioblastoma-secreted C1QL1 orchestrates tumor microtube expansion and neural synaptic pruning to drive malignant synapse formation and recurrence
👉 https://doi.org/10.1158/2159-8290.cd-25-1123

Sleep disturbance triggers aberrant activation of vagus circuitry and induces intestinal stem cell dysfunction
👉 https://www.cell.com/cell-stem-cell/fulltext/S1934-5909(26)00025-1

Hypothalamic clock governs circadian pain
👉 https://www.science.org/doi/10.1126/science.ady6455

A sympathetic-eosinophil axis orchestrates psychological stress to exacerbate skin inflammation
👉 https://www.science.org/doi/10.1126/science.adv5974

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Brain Case @braincase.bsky.social · 17/03/2026

🧠 AAV11: Precision Tool for Microglia Research 🔬 Efficient, microglia-specific gene delivery across brain & spinal cord. Perfect for detailed microglia labeling. 🌟 Collab? kz.lin@siat.ac.cn | BD@ebraincase.com www.ebraincase.com/support/lite... #AAV11 #Microglia #Neuroscience #GeneDelivery

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Brain Case @braincase.bsky.social · 06/03/2026

Saluting every woman for your strength and courage. Wishing you a joyful and radiant Women’s Day! 🌟💐

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Brain Case @braincase.bsky.social · 25/02/2026

🤩Teamwork, Talent, and Tons of Laughter: Our Annual Event Recap! ✨ Here’s to good times, great performances, and even better colleagues! www.ebraincase.com #TeamCelebration #WorkHardPlayHard #OfficeFun #TeamBonding #AnnualEventFun

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Brain Case @braincase.bsky.social · 16/01/2026

💥Brain Case Biotech – Most Popular Product Series | Episode 1 1️⃣ Red-shifted Ca2+indicator（SomaFRCaMPi&Red-shifted K+ indicator(RGEPO1/2) 2️⃣ GRAB Neurotransmitter Sensors 3️⃣ Ultra-stable Monomeric Red Fluorescent Protein 4️⃣ rAAV-miniBEND System for Brain Vasculature 📍 www.ebraincase.com/news/corpora...

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Brain Case @braincase.bsky.social · 25/12/2025

🐱✨ Dr. Bu Goodies Showcase | Episode 4 Meet the next little companions in our Dr. Bu themed goodies showcase — the BuBu notebook, fridge magnets, and Lidong keychain 💙💚 www.ebraincase.com #DrBu #BuBu #BrainCaseBiotech #BrandCulture #ScienceMascot #LabLife #BiotechCommunity #BuBuShowcase

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Brain Case @braincase.bsky.social · 25/12/2025

🐱✨ Dr. Bu Goodies Showcase | Episode 3 Meet the next cozy companions in our Dr. Bu themed goodies showcase — the BuBu mug & glass cup, along with a canvas bag and eye mask 💙💚 www.ebraincase.com #DrBu #BuBu #BrainCaseBiotech #BrandCulture #ScienceMascot #LabLife #BiotechCommunity #BuBuShowcase

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Brain Case @braincase.bsky.social · 25/12/2025

🐱✨ Dr. Bu Goodies Showcase | Episode 2 Meet the next essentials in our Dr. Bu themed goodies showcase — the BuBu phone stand & stickers, mouse pad, and mini timer 💙💚 BuBu is always by your side in the lab. 🐾 Stay tuned for more Dr. Bu surprises! www.ebraincase.com #BrandCulture #ScienceMascot

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Brain Case @braincase.bsky.social · 23/12/2025

🐱✨ Dr. Bu Goodies Showcase | Episode 1 Meet the first stars of our Dr. Bu themed goodies showcase — the BuBu plush toy and pillow 💙💚 This is just the beginning.🧬 Welcome to BuBu’s world — stay tuned for more Dr. Bu surprises! 🐾 www.ebraincase.com #BrainCaseBiotech #BrandCulture #ScienceMascot

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Brain Case @braincase.bsky.social · 19/12/2025

🐱🧬 Meet Dr. Bu! Say hello to Dr. Bu — the official mascot of Brain Case Biotech 💙💚 Also known as BuBu, I’m your friendly lab cat, born from every case worth exploring. Cute in the lab, serious about science.🔬✨ Nice to meet you! 🐾 www.ebraincase.com #BrainCaseBiotech #mascot #LabCat #Neuroscience

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Brain Case @braincase.bsky.social · 18/12/2025

🎄2025 Research Impact Snapshot✨ 🧬From vector design to in vivo validation, we support neuroscience research across the full early research pipeline. 🔗 www.ebraincase.com We’re grateful to be part of this journey—and look forward to advancing science together in the year ahead. #Neuroscience #Virus

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Brain Case @braincase.bsky.social · 20/11/2025

🧬Tongji University developed thoracic spinal cord organoids (enTsOrg) using iPSCs, LDH, and Matrigel, enabling motor function recovery in an SCI mouse model. Brain Case Biotech is honored to have provided the viral vector tools. www.ebraincase.com/support/cust... #Neuroscience #Organoids #BrainCase

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Brain Case @braincase.bsky.social · 26/09/2025

🎉 LIVE at CNS 2025 Xi’an! Visit Booth T9 to play our fun game, win exclusive Brain Case gifts 🐱✨, and grab the 2025 Neuroscience Frontier Handbook! 📅 Sept 25–28 | Xi’an International Convention & Exhibition Center www.ebraincase.com/news/corpora... #CNS2025 #CNSXiAn #Neuroscience #BrainScience

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Brain Case @braincase.bsky.social · 10/09/2025

🎗️World Suicide Prevention Day💙 Today, we stand together for understanding, prevention & hope. To anyone struggling: you are not alone. Please reach out for help, and remember—hope is always on the horizon 🌹🌹 www.ebraincase.com #WorldSuicidePreventionDay #HopeOnTheHorizon #MentalHealth

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Brain Case @braincase.bsky.social · 18/08/2025

🧬 Power your research with Brain Case! Ready-to-use viral vectors for neuroscience & tumor immunology: RABV • PRV • HSV • VSV. Reliable tools. Broad applications. Faster discoveries. 👉Explore our full Product Library: www.ebraincase.com/virus-produc... #Neuroscience #NeuroResearch #ViralVectors

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Brain Case @braincase.bsky.social · 22/07/2025

🔬Explore our cutting-edge service combining neural circuit tracing, spatial transcriptomics, and neuronal subtype analysis—empowering researchers to decode brain connectivity and cell identity with precision. 🧠 📍 www.ebraincase.com/news/corpora... #Neuroscience #SpatialOmics #AAV #BrainResearch

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Brain Case @braincase.bsky.social · 17/07/2025

🧠Customer article Sharing ✨ New study reveals how social status and sex shape #METH addiction via distinct dopamine pathways. Females show high vulnerability regardless of rank. Viral tools used are available from Brain Case Biotech. 📍 www.ebraincase.com/support/cust... #Neuroscience #Addiction

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Brain Case @braincase.bsky.social · 11/07/2025

New Cell study reveals that the meningeal lymphatics–microglia axis regulates synaptic balance and cognition via IL-6. Enhancing lymphatic function in aged mice restores memory and inhibitory signaling—offering a new target for #neurodegenerative therapy. www.ebraincase.com/support/lite...

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Brain Case @braincase.bsky.social · 09/07/2025

🎉Customer article~ Fudan University researchers identify two distinct #neuron subtypes—CB⁺and PV⁺—in the medial mammillary body (MM).These neurons form parallel,non-overlapping #circuits and play differential roles in behavior,such as motor regulation and aversion. www.ebraincase.com/support/cust...

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Brain Case @braincase.bsky.social · 07/07/2025

🚨 New Arrival Alert! Introducing PRV803 – a high-brightness red PRV virus optimized for peripheral nervous system tracing. Enhanced fluorescence, no need for amplification. Fast, clear, and reliable. 👉 Learn more: www.ebraincase.com/news/new-pro... #PRV803 #Neuroscience #NeuralTracing #BrianCase

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Brain Case @braincase.bsky.social · 04/07/2025

📢Client #Publication Spotlight This study reveals how microglia-derived IL-6 induces astrocyte apoptosis in the hippocampus, driving anxiety- and #depression- like behaviors in a CSDS model. 🔗 www.ebraincase.com/support/cust... #Neuroscience #DepressionResearch #Microglia #Astrocyte #IL6 #P2X7R

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Brain Case @braincase.bsky.social · 02/07/2025

🧠Customer article sharing|Why do some animals keep running,while others quickly adapt? A new #Neuron study from Liping Wang & Xuemei Liu’s team at SIAT uncovers two distinct #neural pathways behind fear response habituation to repeated looming stimuli. 📖Read more: www.ebraincase.com/support/cust...

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Brain Case @braincase.bsky.social · 01/07/2025

🔬 SUMMER PROMOTION 2025 | Brain Case Biotech Unlock Exclusive Savings on #ViralVectors & Custom Services — Limited Time Only! ✨ Get 15% OFF #AAV serotypes (AAV5, AAV8, AAV9, Retro, PHP.eB) ✅ 10% OFF #RV, #HSV & #PRV 🎁 Up to 30% OFF custom AAV packaging fees www.ebraincase.com/news/corpora...

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Brain Case @braincase.bsky.social · 26/06/2025

🧠 Customer Article Spotlight | #ScienceAdvances! Siyu Zhang and Min Xu systematically reveal for the first time the whole-brain connectivity maps of two #BFCN subtypes: BFCN→ACA (anterior cingulate cortex) and BFCN→BLA (basolateral amygdala). www.ebraincase.com/support/cust... #Neuroscience #AAV

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Brain Case @braincase.bsky.social · 23/06/2025

🚀 Curious about the science behind AAV vectors in gene therapy? From vector design and clinical breakthroughs to immune barriers and future innovations—this Nature review unpacks it all. 👉 www.ebraincase.com/support/lite... #GeneTherapy #AAV #GeneticEngineering #CellAndGeneTherapy #ViralVectors

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Brain Case @braincase.bsky.social · 20/06/2025

🔬 New from Science: The far-red dopamine sensor HaloDA1.0 enables real-time, multiplex imaging of neurochemical signals (DA, ACh, cAMP) across brain systems—from cultured neurons to freely moving mice. Now available at Brain Case. 📖: www.ebraincase.com/support/lite... #Neuroscience #ImagingTools

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Brain Case @braincase.bsky.social · 17/06/2025

Introducing ATLAS—a modular, activity-dependent tool for forward monosynaptic transsynaptic tracing. No toxicity, no viral replication. Ideal for mapping behaviorally relevant circuits across species. A true breakthrough in connectomics. www.ebraincase.com/support/lite... #Neuroscience #ATLAS

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Brain Case @braincase.bsky.social · 11/06/2025

🧬 How does the brain know when it needs sleep? 📖🧠New findings reveal that cytosolic H₂O₂ in SNr neurons tracks sleep pressure and drives sleep onset—until it goes too far. A balance of oxidative signals may be key to restful sleep. www.ebraincase.com/support/cust... #Neuroscience #SleepResearch

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Brain Case @braincase.bsky.social · 06/06/2025

🧠 Glia aren’t just supporting actors—they’re sculptors. A new Nature paper shows astrocytes in the adult hippocampus actively phagocytose excitatory synapses using AAV-based reporters. Quiet pruning, powerful impact. www.ebraincase.com/support/lite... #Astrocytes #Neuroscience #SynapsePhagocytosis

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Brain Case @braincase.bsky.social · 04/06/2025

🧬 The Allen Institute unveils 15 driver and 2 reporter transgenic mouse lines for precise cortical cell targeting. Paired with 1000+ enhancer AAVs, these tools offer powerful access to fine neuronal subtypes. 🔗 Explore more: www.cell.com/cell/fulltex... #Neuroscience #GeneticTools #AAV

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Brain Case @braincase.bsky.social · 30/05/2025

🎉 It’s Dragon Boat Festival time! From racing dragons to the rich aroma of zongzi, this season calls us to remember ancient wisdom and enduring spirit. 🐉📜 #DragonBoatFestival #ZongziSeason #CulturalHeritage

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Brain Case @braincase.bsky.social · 30/05/2025

🧠🎉 Customer article spotlight: In male mice, testosterone-activated Glu-mPOA neurons trigger GABA-vlPAG circuits, driving sex-specific conditioned pain hypersensitivity. Read more: www.ebraincase.com/sup.../custo... #Neuroscience #PainResearch #SexDifferences #AndrogenReceptor #Neurocircuits

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Brain Case @braincase.bsky.social · 29/05/2025

☀️🧠💥Smiles, sunshine, and team spirit! Here’s a glimpse into our fun day out at Brain Case — celebrating collaboration, connection, and a whole lot of laughs. 💙 www.ebraincase.com #TeamFun #CompanyCulture #SmilesAllAround

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Brain Case @braincase.bsky.social · 27/05/2025

Introducing HypnoS—A high-performance fluorescent sensor spatiotemporally reveals cell-type specific regulation of intracellular adenosine in vivo 🔗 Insight into the Nature Communications article： www.ebraincase.com/support/lite... #Neuroscience #Adenosine #LiveImaging #Sleep #Seizure #HypnoS

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